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M. smegmatis MC2 155 MSMEG_4309 (-)

annotation: low molecular weight protein-tyrosine-phosphatase
coordinates: 4399258 - 4399749
length: 163

VSELHVTFVCSGNICRSPMAEKMFAHQIAERGLRDVVRVTSAGTGSWHAGDGADERACLVLADRGYPTAH
RAAVVDDDHLSADLVVAMGRNHARILADLGVEPDRLRMLRSFDPRAGAHTPDVEDPYYGTRDDFEAVFEV
IEAALPGLHDWVDEALAARGIVA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4309--100% (163)low molecular weight protein-tyrosine-phosphatase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2258ptpA8e-6371.97% (157) phosphotyrosine protein phosphatase PTPA
M. gilvum PYR-GCKMflv_2888-3e-6573.25% (157) protein tyrosine phosphatase
M. tuberculosis H37RvRv2234ptpA8e-6371.97% (157) phosphotyrosine protein phosphatase PTPA
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1900c-3e-6571.70% (159) putative low molecular weight protein tyrosine phosphatase
M. marinum MMMAR_3309ptpA2e-6473.91% (161) phosphotyrosine protein phosphatase PtpA
M. avium 104MAV_2206-5e-6472.67% (161) low molecular weight protein-tyrosine-phosphatase
M. thermoresistible (build 8)TH_1463ptpA4e-6976.25% (160) PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPA
M. ulcerans Agy99MUL_1319ptpA1e-6473.91% (161) phosphotyrosine protein phosphatase PtpA
M. vanbaalenii PYR-1Mvan_3622-1e-6574.38% (160) protein tyrosine phosphatase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_4309|M.smegmatis_MC2_155      MSEL--HVTFVCSGNICRSPMAEKMFAHQIAERGLRDVVRVTSAGTGSWH
MAB_1900c|M.abscessus_ATCC_199      MSEL--HVTFVCTGNICRSPIAEKMLAHQLAERGLADRVRVTSAGTGDWH
Mb2258|M.bovis_AF2122/97            MSDP-LHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDAVRVTSAGTGNWH
Rv2234|M.tuberculosis_H37Rv         MSDP-LHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDAVRVTSAGTGNWH
MAV_2206|M.avium_104                MSEP-LHVTFVCTGNICRSVMAEKMFADQLRRRGMADAVRVSSAGTGNWH
MMAR_3309|M.marinum_M               MSDSTLHVTFVCTGNICRSPMAEKMFAHQLRERGLGEAVRVTSAGTGNWH
MUL_1319|M.ulcerans_Agy99           MSDSTLHVTFVCTGNICRSPMAEKMFAHQLRERGLGEAVRVTSAGTGNWH
Mflv_2888|M.gilvum_PYR-GCK          MSEE-LHVTFVCSGNICRSPMAEKMFAHQIDGRGLAGVVRVTSAGTGHWH
Mvan_3622|M.vanbaalenii_PYR-1       MSEL-LHVTFICSGNICRSPMAEKMFAHQIGERGLAHVVRVTSAGTGHWH
TH_1463|M.thermoresistible__bu      VSDL-LHVTFVCSGNICRSPMAEKMFAHQIAQRGLADAMRVTSAGTGGWH
                                    :*:   ****:*:****** :****:*.*:  **:   :**:***** **

MSMEG_4309|M.smegmatis_MC2_155      AGDGADERACLVLADRGYPTAHRAAVVDDDHLSADLVVAMGRNHARILAD
MAB_1900c|M.abscessus_ATCC_199      AGQPADERASSVLAEYGYPTAHRAAQVDEDHLSADLIIALARNHSRMLLH
Mb2258|M.bovis_AF2122/97            VGSCADERAAGVLRAHGYPTDHRAAQVGTEHLAADLLVALDRNHARLLRQ
Rv2234|M.tuberculosis_H37Rv         VGSCADERAAGVLRAHGYPTDHRAAQVGTEHLAADLLVALDRNHARLLRQ
MAV_2206|M.avium_104                VGECADERAAGVLRAHGYPTEHRAAQVGAEHLSADLVVALDRNHARMLRH
MMAR_3309|M.marinum_M               VGNRADERARQVLHSHGYPTDHCAAQVGTDHLEADLVIALGRNHARQLRQ
MUL_1319|M.ulcerans_Agy99           VGNRADERARQVLYSHGYPTDHCAAQVGTDHLEADLVIALGRNHARQLRQ
Mflv_2888|M.gilvum_PYR-GCK          EGEPADRRASHTLREHGYPTTHRAAQITDEHLAADLVVALGRNHLRMLQH
Mvan_3622|M.vanbaalenii_PYR-1       EGEPADRRAGHVLRAHGYPSSHRATQINDDHLAADLVVALGRNHQRMLQH
TH_1463|M.thermoresistible__bu      VGAPADERARRTLRANGYPTDHRAAQLDDDHLSADLVVPMGRNHQRILVD
                                     *  **.**  .*   ***: * *: :  :** ***::.: *** * * .

MSMEG_4309|M.smegmatis_MC2_155      LGVEPDRLRMLRSFDPRAGAHTPDVEDPYYGTRDDFEAVFEVIEAALPGL
MAB_1900c|M.abscessus_ATCC_199      LGADPERVRLLRSFDPRASRAAMDVEDPYYGNRKDFVEVLAVIEAALPGV
Mb2258|M.bovis_AF2122/97            LGVEAARVRMLRSFDPRSGTHALDVEDPYYGDHSDFEEVFAVIESALPGL
Rv2234|M.tuberculosis_H37Rv         LGVEAARVRMLRSFDPRSGTHALDVEDPYYGDHSDFEEVFAVIESALPGL
MAV_2206|M.avium_104                LGVDEDRIRMLRSFDPRTGAHTPDVDDPYYGDSKDFERVYTVIEAALPGL
MMAR_3309|M.marinum_M               LGVEESRLRMLRSFDPRSGAYVLDVEDPYYGGHDDFEEVLVVIEAALPGL
MUL_1319|M.ulcerans_Agy99           LGVEESRLRMLRSFDPRSGAYVLDVEDPYYGGHDDFEEVLVVIEAALPGL
Mflv_2888|M.gilvum_PYR-GCK          MGVPAERLRMLRSFDPRSGAHVLDVEDPYYGTQDDFEETFAVIDASLPGL
Mvan_3622|M.vanbaalenii_PYR-1       MGVPAERLRMLRSFDPRSGAHVLDVEDPYYGTHDDFEDVFTVIDAALPGL
TH_1463|M.thermoresistible__bu      LGVPHDRLRMLRSFDPRSGAHALDVEDPYYGTQSDFDEVFRVIDASLPGL
                                    :*.   *:*:*******:.  . **:*****  .**  .  **:::***:

MSMEG_4309|M.smegmatis_MC2_155      HDWVDEALAARGIVA
MAB_1900c|M.abscessus_ATCC_199      HEWVDKTLAERENS-
Mb2258|M.bovis_AF2122/97            HDWVDERLARNGPS-
Rv2234|M.tuberculosis_H37Rv         HDWVDERLARNGPS-
MAV_2206|M.avium_104                HDWVDERLAQNGSS-
MMAR_3309|M.marinum_M               HDWVDEQLAQDGKV-
MUL_1319|M.ulcerans_Agy99           HDWVDEQLAQDGKV-
Mflv_2888|M.gilvum_PYR-GCK          HSWVDERLAGREQAG
Mvan_3622|M.vanbaalenii_PYR-1       HGWVDERLADREQVG
TH_1463|M.thermoresistible__bu      HEWVDEQLDARGLAS
                                    * ***: *