For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VSDPLHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDAVRVTSAGTGNWHVGSCADERAAGVLRAHGYPTD HRAAQVGTEHLAADLLVALDRNHARLLRQLGVEAARVRMLRSFDPRSGTHALDVEDPYYGDHSDFEEVFA VIESALPGLHDWVDERLARNGPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2234 | ptpA | - | 100% (163) | PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPA (PROTEIN-TYROSINE-PHOSPHATASE) (PTPase) (LMW PHOSPHATASE) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2258 | ptpA | 3e-94 | 100.00% (163) | phosphotyrosine protein phosphatase PTPA |
| M. gilvum PYR-GCK | Mflv_2888 | - | 2e-65 | 72.78% (158) | protein tyrosine phosphatase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1900c | - | 3e-60 | 68.83% (154) | putative low molecular weight protein tyrosine phosphatase |
| M. marinum M | MMAR_3309 | ptpA | 3e-73 | 80.25% (162) | phosphotyrosine protein phosphatase PtpA |
| M. avium 104 | MAV_2206 | - | 8e-78 | 80.98% (163) | low molecular weight protein-tyrosine-phosphatase |
| M. smegmatis MC2 155 | MSMEG_4309 | - | 1e-62 | 71.97% (157) | low molecular weight protein-tyrosine-phosphatase |
| M. thermoresistible (build 8) | TH_1463 | ptpA | 5e-66 | 72.05% (161) | PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPA |
| M. ulcerans Agy99 | MUL_1319 | ptpA | 4e-73 | 80.25% (162) | phosphotyrosine protein phosphatase PtpA |
| M. vanbaalenii PYR-1 | Mvan_3622 | - | 5e-66 | 72.15% (158) | protein tyrosine phosphatase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_1900c|M.abscessus_ATCC_199 MSEL--HVTFVCTGNICRSPIAEKMLAHQLAERGLADRVRVTSAGTGDWH
MSMEG_4309|M.smegmatis_MC2_155 MSEL--HVTFVCSGNICRSPMAEKMFAHQIAERGLRDVVRVTSAGTGSWH
Rv2234|M.tuberculosis_H37Rv MSDP-LHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDAVRVTSAGTGNWH
Mb2258|M.bovis_AF2122/97 MSDP-LHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDAVRVTSAGTGNWH
MAV_2206|M.avium_104 MSEP-LHVTFVCTGNICRSVMAEKMFADQLRRRGMADAVRVSSAGTGNWH
MMAR_3309|M.marinum_M MSDSTLHVTFVCTGNICRSPMAEKMFAHQLRERGLGEAVRVTSAGTGNWH
MUL_1319|M.ulcerans_Agy99 MSDSTLHVTFVCTGNICRSPMAEKMFAHQLRERGLGEAVRVTSAGTGNWH
Mflv_2888|M.gilvum_PYR-GCK MSEE-LHVTFVCSGNICRSPMAEKMFAHQIDGRGLAGVVRVTSAGTGHWH
Mvan_3622|M.vanbaalenii_PYR-1 MSEL-LHVTFICSGNICRSPMAEKMFAHQIGERGLAHVVRVTSAGTGHWH
TH_1463|M.thermoresistible__bu VSDL-LHVTFVCSGNICRSPMAEKMFAHQIAQRGLADAMRVTSAGTGGWH
:*: ****:*:****** :****:*.*: **: :**:***** **
MAB_1900c|M.abscessus_ATCC_199 AGQPADERASSVLAEYGYPTAHRAAQVDEDHLSADLIIALARNHSRMLLH
MSMEG_4309|M.smegmatis_MC2_155 AGDGADERACLVLADRGYPTAHRAAVVDDDHLSADLVVAMGRNHARILAD
Rv2234|M.tuberculosis_H37Rv VGSCADERAAGVLRAHGYPTDHRAAQVGTEHLAADLLVALDRNHARLLRQ
Mb2258|M.bovis_AF2122/97 VGSCADERAAGVLRAHGYPTDHRAAQVGTEHLAADLLVALDRNHARLLRQ
MAV_2206|M.avium_104 VGECADERAAGVLRAHGYPTEHRAAQVGAEHLSADLVVALDRNHARMLRH
MMAR_3309|M.marinum_M VGNRADERARQVLHSHGYPTDHCAAQVGTDHLEADLVIALGRNHARQLRQ
MUL_1319|M.ulcerans_Agy99 VGNRADERARQVLYSHGYPTDHCAAQVGTDHLEADLVIALGRNHARQLRQ
Mflv_2888|M.gilvum_PYR-GCK EGEPADRRASHTLREHGYPTTHRAAQITDEHLAADLVVALGRNHLRMLQH
Mvan_3622|M.vanbaalenii_PYR-1 EGEPADRRAGHVLRAHGYPSSHRATQINDDHLAADLVVALGRNHQRMLQH
TH_1463|M.thermoresistible__bu VGAPADERARRTLRANGYPTDHRAAQLDDDHLSADLVVPMGRNHQRILVD
* **.** .* ***: * *: : :** ***::.: *** * * .
MAB_1900c|M.abscessus_ATCC_199 LGADPERVRLLRSFDPRASRAAMDVEDPYYGNRKDFVEVLAVIEAALPGV
MSMEG_4309|M.smegmatis_MC2_155 LGVEPDRLRMLRSFDPRAGAHTPDVEDPYYGTRDDFEAVFEVIEAALPGL
Rv2234|M.tuberculosis_H37Rv LGVEAARVRMLRSFDPRSGTHALDVEDPYYGDHSDFEEVFAVIESALPGL
Mb2258|M.bovis_AF2122/97 LGVEAARVRMLRSFDPRSGTHALDVEDPYYGDHSDFEEVFAVIESALPGL
MAV_2206|M.avium_104 LGVDEDRIRMLRSFDPRTGAHTPDVDDPYYGDSKDFERVYTVIEAALPGL
MMAR_3309|M.marinum_M LGVEESRLRMLRSFDPRSGAYVLDVEDPYYGGHDDFEEVLVVIEAALPGL
MUL_1319|M.ulcerans_Agy99 LGVEESRLRMLRSFDPRSGAYVLDVEDPYYGGHDDFEEVLVVIEAALPGL
Mflv_2888|M.gilvum_PYR-GCK MGVPAERLRMLRSFDPRSGAHVLDVEDPYYGTQDDFEETFAVIDASLPGL
Mvan_3622|M.vanbaalenii_PYR-1 MGVPAERLRMLRSFDPRSGAHVLDVEDPYYGTHDDFEDVFTVIDAALPGL
TH_1463|M.thermoresistible__bu LGVPHDRLRMLRSFDPRSGAHALDVEDPYYGTQSDFDEVFRVIDASLPGL
:*. *:*:*******:. . **:***** .** . **:::***:
MAB_1900c|M.abscessus_ATCC_199 HEWVDKTLAERENS-
MSMEG_4309|M.smegmatis_MC2_155 HDWVDEALAARGIVA
Rv2234|M.tuberculosis_H37Rv HDWVDERLARNGPS-
Mb2258|M.bovis_AF2122/97 HDWVDERLARNGPS-
MAV_2206|M.avium_104 HDWVDERLAQNGSS-
MMAR_3309|M.marinum_M HDWVDEQLAQDGKV-
MUL_1319|M.ulcerans_Agy99 HDWVDEQLAQDGKV-
Mflv_2888|M.gilvum_PYR-GCK HSWVDERLAGREQAG
Mvan_3622|M.vanbaalenii_PYR-1 HGWVDERLADREQVG
TH_1463|M.thermoresistible__bu HEWVDEQLDARGLAS
* ***: *