For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
GPPGRDRRRRSGWADQRGIRGPAQAAPGERRTQAGQRDFEGGVGFLRCRARPAVSVVVEFISAHQHMRVG ADGLKWGVESMCAVLSEFGVVIAPSTYYAHRARRGPSKADWTDAQVIDAIWRLRRSNKLFAVLGARKTWI VLRTNGLDVSRCVVERVMREMGWRGACKRRRVRTTIADPAATRAPDRVARHFVAGAPDRLWVADFTYCRT RAGWAYTAFVTDVYARKIVGWKVATEMTQKLVTDAINHAIDTRKRSGAKFLDDLIHHSDAGSQYTAVAFT EHLAAEGILPSVGSVGDCLLTG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4646 | - | - | 100% (303) | hypothetical protein Mflv_4646 |
| M. gilvum PYR-GCK | Mflv_3221 | - | e-175 | 99.66% (298) | integrase catalytic subunit |
| M. gilvum PYR-GCK | Mflv_2788 | - | e-139 | 99.58% (240) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2838c | - | 9e-55 | 51.69% (207) | transposase |
| M. tuberculosis H37Rv | Rv3475 | - | 1e-76 | 52.77% (271) | transposase IS6110 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2088 | - | 4e-12 | 26.42% (212) | transposase |
| M. marinum M | MMAR_2548 | - | 3e-54 | 51.87% (214) | transposase, ISMyma03_aa2 |
| M. avium 104 | MAV_5093 | - | 7e-46 | 44.10% (229) | transposase |
| M. smegmatis MC2 155 | MSMEG_1721 | - | 1e-129 | 91.67% (240) | IS1137, transposase orfB |
| M. thermoresistible (build 8) | TH_3317 | - | 4e-39 | 40.91% (242) | PUTATIVE Integrase, catalytic region |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5973 | - | 1e-38 | 44.17% (206) | integrase catalytic subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2838c|M.bovis_AF2122/97 --------------------------------------------------
Rv3475|M.tuberculosis_H37Rv ----------------------AEALAAGQRRIAKGERDFKDRVGFLRGR
Mflv_4646|M.gilvum_PYR-GCK MGPPGRDRRRRSGWADQRGIRGPAQAAPGERRTQAGQRDFEGGVGFLRCR
MSMEG_1721|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2548|M.marinum_M --------------------------------------------------
MAV_5093|M.avium_104 --------------------------------------------------
Mvan_5973|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3317|M.thermoresistible__bu --------------------------------------------------
MAB_2088|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2838c|M.bovis_AF2122/97 ----------------------------------------MPIAPSTYYD
Rv3475|M.tuberculosis_H37Rv ARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYD
Mflv_4646|M.gilvum_PYR-GCK ARPAVSVVVEFISAHQHMRVGADGLKWGVESMCAVLSEFGVVIAPSTYYA
MSMEG_1721|M.smegmatis_MC2_155 --------MEFISAHQHMRVGVDGLKWGVESMCAVLSEYGVTIAPSTYYA
MMAR_2548|M.marinum_M ----------------------------------MLTEHGIKISPSTYYE
MAV_5093|M.avium_104 --------MAFIDANRDE--------FGVEPICTVLRSAGLQVAPST-YY
Mvan_5973|M.vanbaalenii_PYR-1 ------------------------------------------MAPST-YY
TH_3317|M.thermoresistible__bu -------MIAFIDAHRDQ--------FGVELICRVLRAAIAGFLTSRGYR
MAB_2088|M.abscessus_ATCC_1997 -----------------------------------MTRRVLKLARQPYYR
. . *
Mb2838c|M.bovis_AF2122/97 HINRE-PSRRELRDGELKEHISRVHAAN--YGVYGARKVWLTLNREGIEV
Rv3475|M.tuberculosis_H37Rv HINRE-PSRRELRDGELKEHISRVHAAN--YGVYGARKVWLTLNREGIEV
Mflv_4646|M.gilvum_PYR-GCK HRARRGPSKADWTDAQVIDAIWRLRRSNKLFAVLGARKTWIVLRTNGLDV
MSMEG_1721|M.smegmatis_MC2_155 HRARQGPSKADWADAQVIDAIWQLRQSQSLYRVLGARKTWIVLRTNGIDV
MMAR_2548|M.marinum_M WMKRT-PSKQQLRDEAVTASIKEFRERNPLNKTLGSRKVWIKLRGDGMDV
MAV_5093|M.avium_104 ANKTRTPSARAQRDAVMRPVITQLWEDN--YRVYGARKLWKAARRAGHDI
Mvan_5973|M.vanbaalenii_PYR-1 DVKSRCPSARARRDAELGPALRVIWEDN--YRVYGAVKLWKAARRGGHDV
TH_3317|M.thermoresistible__bu AAKARPPSERAMRDELLIAELRTVHEQN--FSVYGVKKMHHAMKRRGWRV
MAB_2088|M.abscessus_ATCC_1997 WRANP-ITDAELVEAYRANALFDAHGED---PEFGYRYLVEEAREAGEPM
: : : : * . * :
Mb2838c|M.bovis_AF2122/97 ARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNR
Rv3475|M.tuberculosis_H37Rv ARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNR
Mflv_4646|M.gilvum_PYR-GCK SRCVVERVMREMGWRGACKRRRVRTTIADPAATRAPDRVARHFVAGAPDR
MSMEG_1721|M.smegmatis_MC2_155 SRCVVERVMREMGWRGACKRRRVRTTVADPAATRAPDRVRRNFVAGAPDR
MMAR_2548|M.marinum_M ARCTVERLMQANRWQGARYGGAPKTTIQDEKAQRATDLVDRVFAAPAPNR
MAV_5093|M.avium_104 GRDQIARLMREAGIAGVRRGKRVRTTKPGPGAPRHPDLVGRDFTASAPNQ
Mvan_5973|M.vanbaalenii_PYR-1 GRDQVARLMRSLGIEGVRRGKRVTTTRADPAAPRHPDLVKRQFTATAPNQ
TH_3317|M.thermoresistible__bu GREQTRRLMRKAGLRGVQRGKPVFTTISDPAHCRPADLVNRQFSAEAPDR
MAB_2088|M.abscessus_ATCC_1997 AERTAWRICSQQQLWSVFGKKRGKNGKPGP--PVHDDLVQRDFTAETPNM
.. *: .. . . * * * * . :*:
Mb2838c|M.bovis_AF2122/97 LWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATS-MVLDAIEQ
Rv3475|M.tuberculosis_H37Rv LWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATS-MVLDAIEQ
Mflv_4646|M.gilvum_PYR-GCK LWVADFTYCRTRAGWAYTAFVTDVYARKIVGWKVATEMTQK-LVTDAINH
MSMEG_1721|M.smegmatis_MC2_155 LWVADFTYCRTRAGWAYTAFVTDVYARKIVGWKVATEMTQK-LVTDAIDH
MMAR_2548|M.marinum_M LWVADFTYCPTWAGMVYVAFVIDAFARRVIGWRAATSMKTA-LVIDALEH
MAV_5093|M.avium_104 LWVTDLTFVPTWAGVAYVCFLTDAFSRMIIGWRVASHMRTT-VVLDTIEM
Mvan_5973|M.vanbaalenii_PYR-1 LWVTDLTFVPTWVGVAYVCFIVDAFSRLIVGWRAASNMRTT-MVLDALEM
TH_3317|M.thermoresistible__bu LWVADITFVRTWQGFCYTAFVTDACTKAIKGWAVAASMRTEDLPLEAFNH
MAB_2088|M.abscessus_ATCC_1997 LWLSDITEHYTGDGKLYLCAIKDAFSNRIVGYSIDSRMKSR-LATAALRN
**::*:* * * * . : *. :. : *: : * : ::
Mb2838c|M.bovis_AF2122/97 AIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSS
Rv3475|M.tuberculosis_H37Rv AIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSS
Mflv_4646|M.gilvum_PYR-GCK AIDTRKRSGAKFLDDLIHHSDAGSQYTAVAFTEHLAAEGILPSVGSVGDC
MSMEG_1721|M.smegmatis_MC2_155 AIDTRKRSGAASLDSLIHHSDAGSQYTAVAFTERLAAEGILPSVGSVGDS
MMAR_2548|M.marinum_M AFFTRAQEGFTDLSGLVAHSDAGSQYTSIAFTTRLIDAGIDASVGSVADA
MAV_5093|M.avium_104 ARWSRGKM----LAGLRCHSDAGSQFTSIRYSERLAEIGAVPSIGTVGDS
Mvan_5973|M.vanbaalenii_PYR-1 ARWSRGNT----LSGLRCHSDAGSQFTSIRYGERLAELGAVPSIGSVGDS
TH_3317|M.thermoresistible__bu AVWHSDSD----LSELIHHSDRGSQYLSLTYTDRLAELGIAPSVGSRGDS
MAB_2088|M.abscessus_ATCC_1997 AVGRRGVV-----AGCVVHTDRGSQFRSRKFVQALHHHGMVGSMGRVGAA
* *:* ***: : : * * *:* . .
Mb2838c|M.bovis_AF2122/97 YDNALAETINGLYKTELIKPGK---PWRSIEDVELATARWVD-WFNHRRL
Rv3475|M.tuberculosis_H37Rv YDNALAETINGLYKTELIKPGK---PWRSIEDVELATARWVD-WFNHRRL
Mflv_4646|M.gilvum_PYR-GCK LLTG----------------------------------------------
MSMEG_1721|M.smegmatis_MC2_155 FDNALAESVNSSYKTELIDRQP---LYPGATELALGTAEWVA-FYNRQRP
MMAR_2548|M.marinum_M YDNALAETTVGSFKNELIRRQG---PWRDVDHVEIGTLNWVD-WFNNERP
MAV_5093|M.avium_104 FDNALAETVNGYYKAELIYGPARPGPWKTVEDVELATLSWVH-WHNTSRL
Mvan_5973|M.vanbaalenii_PYR-1 FDNALAERA---CLIDCVSG------WA----------------------
TH_3317|M.thermoresistible__bu YDNALAEAVNAAYKTELINRGK---PWRSVDDVELATAGWVA-WYNQERL
MAB_2088|M.abscessus_ATCC_1997 GDNAAMESFFSLLQKNVLDRRR----WATREELRIAIVTWIERTYHRRRR
..
Mb2838c|M.bovis_AF2122/97 YQYCGDVPPVELEAAYYAQRQRPAAG-------
Rv3475|M.tuberculosis_H37Rv YQYCGDVPPVELEAAYYAQRQRPAAG-------
Mflv_4646|M.gilvum_PYR-GCK ---------------------------------
MSMEG_1721|M.smegmatis_MC2_155 NGYCQDLTPDRAEALYYHRQRHPHAEEALR---
MMAR_2548|M.marinum_M HEYLADLTPTQAEALHYRHKSSLAAAG------
MAV_5093|M.avium_104 HGYLNDVPPAEFEAAFYATKR-TDHPLVEIQ--
Mvan_5973|M.vanbaalenii_PYR-1 ---------------------------------
TH_3317|M.thermoresistible__bu HEALGYVPPAEYEAALTGTSHPASQPTPALATN
MAB_2088|M.abscessus_ATCC_1997 QGALGRLTPVEYEAIMTTTASQAA---------