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EFISAHQHMRVGADGLKWGVESMCAVLSEFGVVIAPSTYYAHRARRGPSKADWTDAQVIDAIWRLRRSNK LFAVLGARKTWIVLRTNGLDVSRCVVERVMREMGWRGACKRRRVRTTIADPAATRAPDRVARHFVAGAPD RLWVADFTYCRTRAGWAYTAFVTDVYARKIVGWKVATEMTQKLVTDAINHAIDTRKRSGATFLDDLIHHS DAGSQYTAVAFTEHLAAEGILPSVGSVGDSFDNALAESVNSSYKTELIDHQPPYPGAAELSLATAEWVAF YNRQRPNGYCQDLTPDRAEALYYHRQRHPHTEEALR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2788 | - | - | 100% (317) | integrase catalytic subunit |
| M. gilvum PYR-GCK | Mflv_3221 | - | 0.0 | 100.00% (317) | integrase catalytic subunit |
| M. gilvum PYR-GCK | Mflv_4646 | - | e-139 | 99.58% (240) | hypothetical protein Mflv_4646 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2838c | - | 2e-74 | 50.00% (278) | transposase |
| M. tuberculosis H37Rv | Rv3475 | - | 1e-85 | 50.97% (308) | transposase IS6110 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2088 | - | 7e-19 | 27.54% (276) | transposase |
| M. marinum M | MMAR_2548 | - | 3e-73 | 50.18% (281) | transposase, ISMyma03_aa2 |
| M. avium 104 | MAV_5093 | - | 3e-62 | 44.08% (304) | transposase |
| M. smegmatis MC2 155 | MSMEG_1721 | - | 1e-173 | 91.80% (317) | IS1137, transposase orfB |
| M. thermoresistible (build 8) | TH_3317 | - | 2e-55 | 43.55% (287) | PUTATIVE Integrase, catalytic region |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5973 | - | 3e-43 | 46.26% (214) | integrase catalytic subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2788|M.gilvum_PYR-GCK ------------------------------------MEFISAHQHMRVGA
MSMEG_1721|M.smegmatis_MC2_155 ------------------------------------MEFISAHQHMRVGV
MMAR_2548|M.marinum_M --------------------------------------------------
Mb2838c|M.bovis_AF2122/97 --------------------------------------------------
Rv3475|M.tuberculosis_H37Rv AEALAAGQRRIAKGERDFKDRVGFLRGRARPASTLITRFIADHQGHREGP
MAV_5093|M.avium_104 ------------------------------------MAFIDANRDE----
Mvan_5973|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3317|M.thermoresistible__bu -----------------------------------MIAFIDAHRDQ----
MAB_2088|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2788|M.gilvum_PYR-GCK DGLKWGVESMCAVLSEFGVVIAPSTYYAHRARRGPSKADWTDAQVIDAIW
MSMEG_1721|M.smegmatis_MC2_155 DGLKWGVESMCAVLSEYGVTIAPSTYYAHRARQGPSKADWADAQVIDAIW
MMAR_2548|M.marinum_M ------------MLTEHGIKISPSTYYEWMKRT-PSKQQLRDEAVTASIK
Mb2838c|M.bovis_AF2122/97 ------------------MPIAPSTYYDHINRE-PSRRELRDGELKEHIS
Rv3475|M.tuberculosis_H37Rv DGLRWGVESICTQLTELGVPIAPSTYYDHINRE-PSRRELRDGELKEHIS
MAV_5093|M.avium_104 ----FGVEPICTVLRSAGLQVAPST-YYANKTRTPSARAQRDAVMRPVIT
Mvan_5973|M.vanbaalenii_PYR-1 --------------------MAPST-YYDVKSRCPSARARRDAELGPALR
TH_3317|M.thermoresistible__bu ----FGVELICRVLRAAIAGFLTSRGYRAAKARPPSERAMRDELLIAELR
MAB_2088|M.abscessus_ATCC_1997 -------------MTRRVLKLARQPYYRWRANP-ITDAELVEAYRANALF
. . * : : :
Mflv_2788|M.gilvum_PYR-GCK RLRRSNKLFAVLGARKTWIVLRTNGLDVSRCVVERVMREMGWRGACKRRR
MSMEG_1721|M.smegmatis_MC2_155 QLRQSQSLYRVLGARKTWIVLRTNGIDVSRCVVERVMREMGWRGACKRRR
MMAR_2548|M.marinum_M EFRERNPLNKTLGSRKVWIKLRGDGMDVARCTVERLMQANRWQGARYGGA
Mb2838c|M.bovis_AF2122/97 RVHAAN--YGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKA
Rv3475|M.tuberculosis_H37Rv RVHAAN--YGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKA
MAV_5093|M.avium_104 QLWEDN--YRVYGARKLWKAARRAGHDIGRDQIARLMREAGIAGVRRGKR
Mvan_5973|M.vanbaalenii_PYR-1 VIWEDN--YRVYGAVKLWKAARRGGHDVGRDQVARLMRSLGIEGVRRGKR
TH_3317|M.thermoresistible__bu TVHEQN--FSVYGVKKMHHAMKRRGWRVGREQTRRLMRKAGLRGVQRGKP
MAB_2088|M.abscessus_ATCC_1997 DAHGED---PEFGYRYLVEEAREAGEPMAERTAWRICSQQQLWSVFGKKR
: * . * :.. *: ..
Mflv_2788|M.gilvum_PYR-GCK VRTTIADPAATRAPDRVARHFVAGAPDRLWVADFTYCRTRAGWAYTAFVT
MSMEG_1721|M.smegmatis_MC2_155 VRTTVADPAATRAPDRVRRNFVAGAPDRLWVADFTYCRTRAGWAYTAFVT
MMAR_2548|M.marinum_M PKTTIQDEKAQRATDLVDRVFAAPAPNRLWVADFTYCPTWAGMVYVAFVI
Mb2838c|M.bovis_AF2122/97 RRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVT
Rv3475|M.tuberculosis_H37Rv RRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVT
MAV_5093|M.avium_104 VRTTKPGPGAPRHPDLVGRDFTASAPNQLWVTDLTFVPTWAGVAYVCFLT
Mvan_5973|M.vanbaalenii_PYR-1 VTTTRADPAAPRHPDLVKRQFTATAPNQLWVTDLTFVPTWVGVAYVCFIV
TH_3317|M.thermoresistible__bu VFTTISDPAHCRPADLVNRQFSAEAPDRLWVADITFVRTWQGFCYTAFVT
MAB_2088|M.abscessus_ATCC_1997 GKNGKPGP--PVHDDLVQRDFTAETPNMLWLSDITEHYTGDGKLYLCAIK
. . * * * * . :*: **::*:* * * * . :
Mflv_2788|M.gilvum_PYR-GCK DVYARKIVGWKVATEMTQK-LVTDAINHAIDTRKRSGATFLDDLIHHSDA
MSMEG_1721|M.smegmatis_MC2_155 DVYARKIVGWKVATEMTQK-LVTDAIDHAIDTRKRSGAASLDSLIHHSDA
MMAR_2548|M.marinum_M DAFARRVIGWRAATSMKTA-LVIDALEHAFFTRAQEGFTDLSGLVAHSDA
Mb2838c|M.bovis_AF2122/97 DAYARRILGWRVASTMATS-MVLDAIEQAIWTRQQEGVLDLKDVIHHTDR
Rv3475|M.tuberculosis_H37Rv DAYARRILGWRVASTMATS-MVLDAIEQAIWTRQQEGVLDLKDVIHHTDR
MAV_5093|M.avium_104 DAFSRMIIGWRVASHMRTT-VVLDTIEMARWSRGK----MLAGLRCHSDA
Mvan_5973|M.vanbaalenii_PYR-1 DAFSRLIVGWRAASNMRTT-MVLDALEMARWSRGN----TLSGLRCHSDA
TH_3317|M.thermoresistible__bu DACTKAIKGWAVAASMRTEDLPLEAFNHAVWHSDS----DLSELIHHSDR
MAB_2088|M.abscessus_ATCC_1997 DAFSNRIVGYSIDSRMKSR-LATAALRNAVGRRGV-----VAGCVVHTDR
*. :. : *: : * : :: * : *:*
Mflv_2788|M.gilvum_PYR-GCK GSQYTAVAFTEHLAAEGILPSVGSVGDSFDNALAESVNSSYKTELIDHQP
MSMEG_1721|M.smegmatis_MC2_155 GSQYTAVAFTERLAAEGILPSVGSVGDSFDNALAESVNSSYKTELIDRQP
MMAR_2548|M.marinum_M GSQYTSIAFTTRLIDAGIDASVGSVADAYDNALAETTVGSFKNELIRRQG
Mb2838c|M.bovis_AF2122/97 GSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGK
Rv3475|M.tuberculosis_H37Rv GSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGK
MAV_5093|M.avium_104 GSQFTSIRYSERLAEIGAVPSIGTVGDSFDNALAETVNGYYKAELIYGPA
Mvan_5973|M.vanbaalenii_PYR-1 GSQFTSIRYGERLAELGAVPSIGSVGDSFDNALAERA---CLIDCVSG--
TH_3317|M.thermoresistible__bu GSQYLSLTYTDRLAELGIAPSVGSRGDSYDNALAEAVNAAYKTELINRGK
MAB_2088|M.abscessus_ATCC_1997 GSQFRSRKFVQALHHHGMVGSMGRVGAAGDNAAMESFFSLLQKNVLDRRR
***: : : * * *:* . : *** * : :
Mflv_2788|M.gilvum_PYR-GCK ---PYPGAAELSLATAEWVA-FYNRQRPNGYCQDLTPDRAEALYYHRQRH
MSMEG_1721|M.smegmatis_MC2_155 ---LYPGATELALGTAEWVA-FYNRQRPNGYCQDLTPDRAEALYYHRQRH
MMAR_2548|M.marinum_M ---PWRDVDHVEIGTLNWVD-WFNNERPHEYLADLTPTQAEALHYRHKSS
Mb2838c|M.bovis_AF2122/97 ---PWRSIEDVELATARWVD-WFNHRRLYQYCGDVPPVELEAAYYAQRQR
Rv3475|M.tuberculosis_H37Rv ---PWRSIEDVELATARWVD-WFNHRRLYQYCGDVPPVELEAAYYAQRQR
MAV_5093|M.avium_104 RPGPWKTVEDVELATLSWVH-WHNTSRLHGYLNDVPPAEFEAAFYATKR-
Mvan_5973|M.vanbaalenii_PYR-1 ----WA--------------------------------------------
TH_3317|M.thermoresistible__bu ---PWRSVDDVELATAGWVA-WYNQERLHEALGYVPPAEYEAALTGTSHP
MAB_2088|M.abscessus_ATCC_1997 ----WATREELRIAIVTWIERTYHRRRRQGALGRLTPVEYEAIMTTTASQ
:
Mflv_2788|M.gilvum_PYR-GCK PHTEEALR---
MSMEG_1721|M.smegmatis_MC2_155 PHAEEALR---
MMAR_2548|M.marinum_M LAAAG------
Mb2838c|M.bovis_AF2122/97 PAAG-------
Rv3475|M.tuberculosis_H37Rv PAAG-------
MAV_5093|M.avium_104 TDHPLVEIQ--
Mvan_5973|M.vanbaalenii_PYR-1 -----------
TH_3317|M.thermoresistible__bu ASQPTPALATN
MAB_2088|M.abscessus_ATCC_1997 AA---------