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VAPSTYYDVKSRCPSARARRDAELGPALRVIWEDNYRVYGAVKLWKAARRGGHDVGRDQVARLMRSLGIE GVRRGKRVTTTRADPAAPRHPDLVKRQFTATAPNQLWVTDLTFVPTWVGVAYVCFIVDAFSRLIVGWRAA SNMRTTMVLDALEMARWSRGNTLSGLRCHSDAGSQFTSIRYGERLAELGAVPSIGSVGDSFDNALAERAC LIDCVSGWA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5973 | - | - | 100% (219) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_3741 | - | 3e-35 | 41.51% (212) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_0583 | - | 3e-35 | 41.51% (212) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2838c | - | 6e-58 | 54.03% (211) | transposase |
| M. gilvum PYR-GCK | Mflv_0599 | - | 1e-68 | 81.21% (149) | integrase, catalytic region |
| M. tuberculosis H37Rv | Rv3475 | - | 6e-58 | 54.03% (211) | transposase IS6110 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2088 | - | 2e-21 | 37.21% (172) | transposase |
| M. marinum M | MMAR_2548 | - | 5e-48 | 46.48% (213) | transposase, ISMyma03_aa2 |
| M. avium 104 | MAV_1454 | - | 1e-100 | 84.54% (207) | transposase |
| M. smegmatis MC2 155 | MSMEG_2818 | - | 5e-48 | 46.55% (232) | ISMsm1, transposase orfB |
| M. thermoresistible (build 8) | TH_3317 | - | 3e-52 | 52.22% (203) | PUTATIVE Integrase, catalytic region |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2838c|M.bovis_AF2122/97 --------------------------------------------------
Rv3475|M.tuberculosis_H37Rv AEALAAGQRRIAKGERDFKDRVGFLRGRARPASTLITRFIADHQGHREGP
Mflv_0599|M.gilvum_PYR-GCK --------------------------------------------------
MAV_1454|M.avium_104 --------------------------------------------------
Mvan_5973|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3317|M.thermoresistible__bu -----------------------------------MIAFIDAHR------
MMAR_2548|M.marinum_M --------------------------------------------------
MSMEG_2818|M.smegmatis_MC2_155 ----------------------------------MIVDYIDAYR------
MAB_2088|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2838c|M.bovis_AF2122/97 -------------------MPIAPSTYYDHINR-EPSRRELRDGELKEHI
Rv3475|M.tuberculosis_H37Rv DGLRWGVESICTQLT-ELGVPIAPSTYYDHINR-EPSRRELRDGELKEHI
Mflv_0599|M.gilvum_PYR-GCK ---------------------MAPSTYYDAKTR-PPSARAQRDAVLGPAL
MAV_1454|M.avium_104 ---------------------MALSTYYDTKAR-VPSARALRDAVLGPAL
Mvan_5973|M.vanbaalenii_PYR-1 ---------------------MAPSTYYDVKSR-CPSARARRDAELGPAL
TH_3317|M.thermoresistible__bu --DQFGVELICRVLRAAIAGFLTSRGYRAAKAR-PPSERAMRDELLIAEL
MMAR_2548|M.marinum_M -------------MLTEHGIKISPSTYYEWMKR-TPSKQQLRDEAVTASI
MSMEG_2818|M.smegmatis_MC2_155 --HRFGVDPIC-AVLSEHDMPIAPSTYYAAKARGPVSDAAWAEAHAANAV
MAB_2088|M.abscessus_ATCC_1997 --------------MTRRVLKLARQPYYRWRAN-PITDAELVEAYRANAL
:: * . : : :
Mb2838c|M.bovis_AF2122/97 SRVHAAN--YGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGK
Rv3475|M.tuberculosis_H37Rv SRVHAAN--YGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGK
Mflv_0599|M.gilvum_PYR-GCK RQLWKDN--YCVYGAHKLWKTARRAGYDVGRDQVARLMRAAGIQGVRRGK
MAV_1454|M.avium_104 CQLWKDN--YCVYGARKLWKTARREGHDVGRDQVARLMRAAGIEGVRRGK
Mvan_5973|M.vanbaalenii_PYR-1 RVIWEDN--YRVYGAVKLWKAARRGGHDVGRDQVARLMRSLGIEGVRRGK
TH_3317|M.thermoresistible__bu RTVHEQN--FSVYGVKKMHHAMKRRGWRVGREQTRRLMRKAGLRGVQRGK
MMAR_2548|M.marinum_M KEFRERNPLNKTLGSRKVWIKLRGDGMDVARCTVERLMQANRWQGARYGG
MSMEG_2818|M.smegmatis_MC2_155 HTVFWAN--RGLYGVRKMWHAMRHAGHDMGRDQVARLMRICGISGAVRGK
MAB_2088|M.abscessus_ATCC_1997 FDAHGED---PEFGYRYLVEEAREAGEPMAERTAWRICSQQQLWSVFGKK
: * : . * :.. . *: ..
Mb2838c|M.bovis_AF2122/97 A-RRTTIADPATARPADLVQRRFGPPA-PNRLWVADLTYVSTWAGFAYVA
Rv3475|M.tuberculosis_H37Rv A-RRTTIADPATARPADLVQRRFGPPA-PNRLWVADLTYVSTWAGFAYVA
Mflv_0599|M.gilvum_PYR-GCK R-VRTTKPDPVAARHPDLVKRKFTATA-PNQLWVTDLTFVPTWAGVAYVC
MAV_1454|M.avium_104 R-VRTTKPDPAAARHPDLVKRNFTATA-PNQLWVTDLTFVPTWAGVAYVC
Mvan_5973|M.vanbaalenii_PYR-1 R-VTTTRADPAAPRHPDLVKRQFTATA-PNQLWVTDLTFVPTWVGVAYVC
TH_3317|M.thermoresistible__bu P-VFTTISDPAHCRPADLVNRQFSAEA-PDRLWVADITFVRTWQGFCYTA
MMAR_2548|M.marinum_M A-PKTTIQDEKAQRATDLVDRVFAAPA-PNRLWVADFTYCPTWAGMVYVA
MSMEG_2818|M.smegmatis_MC2_155 RRTITTASEQGAPRHPDLIERKWGLPVRPDQWWVADFTYTWTLAGFVYTA
MAB_2088|M.abscessus_ATCC_1997 R---GKNGKPGPPVHDDLVQRDFTAET-PNMLWLSDITEHYTGDGKLYLC
. . **:.* : . *: *::*:* * * * .
Mb2838c|M.bovis_AF2122/97 FVTDAYARRILGWRVASTMATS-MVLDAIEQAIWTRQQEGV-LDLKDVIH
Rv3475|M.tuberculosis_H37Rv FVTDAYARRILGWRVASTMATS-MVLDAIEQAIWTRQQEGV-LDLKDVIH
Mflv_0599|M.gilvum_PYR-GCK FIVDAHSRMIVGWRVASHMRTS-MVL-----AQIFRG------LLLVTAC
MAV_1454|M.avium_104 FIIDAYSRMIVGWRVASHMRTS-MVLDALEMARWSRGN-----MLPGLRC
Mvan_5973|M.vanbaalenii_PYR-1 FIVDAFSRLIVGWRAASNMRTT-MVLDALEMARWSRGN-----TLSGLRC
TH_3317|M.thermoresistible__bu FVTDACTKAIKGWAVAASMRTEDLPLEAFNHAVWHSDS-----DLSELIH
MMAR_2548|M.marinum_M FVIDAFARRVIGWRAATSMKTA-LVIDALEHAFFTRAQEGF-TDLSGLVA
MSMEG_2818|M.smegmatis_MC2_155 FCVDVFSRRILGWRVMSTKATP-LVTSVLEQAVFTRRRTDFRFTTTGLVH
MAB_2088|M.abscessus_ATCC_1997 AIKDAFSNRIVGYSIDSRMKSR-LATAALRNAVGRRG------VVAGCVV
*. :. : *: : : : *
Mb2838c|M.bovis_AF2122/97 HTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELI
Rv3475|M.tuberculosis_H37Rv HTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELI
Mflv_0599|M.gilvum_PYR-GCK R-------------------------------------------------
MAV_1454|M.avium_104 HSDAGSQFTSIRYGERLAEIGAVPSIGTVGDSFDNALAETVNGYYKAELI
Mvan_5973|M.vanbaalenii_PYR-1 HSDAGSQFTSIRYGERLAELGAVPSIGSVGDSFDNALAERA---CLIDCV
TH_3317|M.thermoresistible__bu HSDRGSQYLSLTYTDRLAELGIAPSVGSRGDSYDNALAEAVNAAYKTELI
MMAR_2548|M.marinum_M HSDAGSQYTSIAFTTRLIDAGIDASVGSVADAYDNALAETTVGSFKNELI
MSMEG_2818|M.smegmatis_MC2_155 HSDAGSQYTSLAFTDALRDSGIAGSIGSVGDALDNALMESAIGLYKTELI
MAB_2088|M.abscessus_ATCC_1997 HTDRGSQFRSRKFVQALHHHGMVGSMGRVGAAGDNAAMESFFSLLQKNVL
:
Mb2838c|M.bovis_AF2122/97 KPGK---PWRSIEDVELATARWVD-WFNHRRLYQYCGDVPPVELEAAYYA
Rv3475|M.tuberculosis_H37Rv KPGK---PWRSIEDVELATARWVD-WFNHRRLYQYCGDVPPVELEAAYYA
Mflv_0599|M.gilvum_PYR-GCK --------------------------------------------------
MAV_1454|M.avium_104 YGPARTGPWKTVEDVELATLSWVY-WHNTSRLHSYLGDIPPAEFEAAFY-
Mvan_5973|M.vanbaalenii_PYR-1 SGWA----------------------------------------------
TH_3317|M.thermoresistible__bu NRGK---PWRSVDDVELATAGWVA-WYNQERLHEALGYVPPAEYEAALTG
MMAR_2548|M.marinum_M RRQG---PWRDVDHVEIGTLNWVD-WFNNERPHEYLADLTPTQAEALHYR
MSMEG_2818|M.smegmatis_MC2_155 DRHQ---SWTGRAEVERETAAWVH-WYNTDRLHSSLSYQSPIDYEAQYRN
MAB_2088|M.abscessus_ATCC_1997 DRRR----WATREELRIAIVTWIERTYHRRRRQGALGRLTPVEYEAIMTT
Mb2838c|M.bovis_AF2122/97 QRQRPAAG-------
Rv3475|M.tuberculosis_H37Rv QRQRPAAG-------
Mflv_0599|M.gilvum_PYR-GCK ---------------
MAV_1454|M.avium_104 DAYRTDQPLIGIQ--
Mvan_5973|M.vanbaalenii_PYR-1 ---------------
TH_3317|M.thermoresistible__bu TSHPASQPTPALATN
MMAR_2548|M.marinum_M HKSSLAAAG------
MSMEG_2818|M.smegmatis_MC2_155 DAASTPEVA------
MAB_2088|M.abscessus_ATCC_1997 TASQAA---------