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GMTVQPPADEVRLIEADAAPTRFARGWHCLGLIRDFGDGTPHQVNAFGQKLVVFRAEDGSINVLDSYCRH MGGDLSQGTVKGNEIACPFHDWRWGGDGRCKQVPYAKRVPRLARTQTWPTLEQDGMLFVWNDPQRKPPPD DVTIPRIEGATSDEWTDWHWYTTVVHTNCREIIDNVVDMAHFFYIHGSLPTQFKNIFEGHTATQFMSSGG RPDLGQAEGGVKLLGTTSLAAYHGPSFMIDDLTYHYEHGDTKTVLINCHYPIDANSFVLQYGIVVQKSAD LPEDLAVQTAVALGDFVKMGFEQDVQIWRNKARIDNPLLVEEDGPVYQLRRWYEQFYVDVEDVTPDMVDR FEFEIDTTRPRESWMKEVEDNIAAGRIPKLASGTT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4566 | - | - | 100% (386) | Rieske (2Fe-2S) domain-containing protein |
| M. gilvum PYR-GCK | Mflv_1533 | - | e-129 | 56.96% (381) | Rieske (2Fe-2S) domain-containing protein |
| M. gilvum PYR-GCK | Mflv_1546 | - | e-117 | 55.19% (366) | Rieske (2Fe-2S) domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3556 | - | 1e-131 | 58.22% (371) | oxidoreductase |
| M. tuberculosis H37Rv | Rv3526 | - | 1e-131 | 58.22% (371) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0080c | - | 1e-174 | 75.62% (365) | putative oxygenase |
| M. marinum M | MMAR_5015 | - | 1e-130 | 57.68% (371) | oxidoreductase |
| M. avium 104 | MAV_3037 | - | 0.0 | 81.97% (366) | oxygenase KshA |
| M. smegmatis MC2 155 | MSMEG_2870 | - | 0.0 | 81.77% (373) | oxygenase KshA |
| M. thermoresistible (build 8) | TH_0323 | - | 0.0 | 81.67% (371) | POSSIBLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_4089 | - | 1e-130 | 57.41% (371) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_2869 | - | 0.0 | 79.05% (377) | Rieske (2Fe-2S) domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2870|M.smegmatis_MC2_155 ---MTSLQPDGGAGEVRQIEAQAAPTRFARGWHCLGLIRELGDGKPHAIN
TH_0323|M.thermoresistible__bu MAGMTSLQSDRDTGEVRQIEAQAVPTRFARGWHCLGLIDDLGDGKPHAIN
Mvan_2869|M.vanbaalenii_PYR-1 ---MTSLQSD-GAADVRQIEAQAAPTRFARGWHCLGLTSDLGDGQPHAIN
Mflv_4566|M.gilvum_PYR-GCK ----MGMTVQPPADEVRLIEADAAPTRFARGWHCLGLIRDFGDGTPHQVN
MAV_3037|M.avium_104 ---------MHDTDEVRLIEAQAVPTRFARGWHCLGLIRDFGDGKPHPIN
MAB_0080c|M.abscessus_ATCC_199 -MTTAQSATEFDPATVRSIEADAAPARFARGWYCLGLIKDFGDGKPHAVN
Mb3556|M.bovis_AF2122/97 ------MSTDTSGVGVREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVE
Rv3526|M.tuberculosis_H37Rv ------MSTDTSGVGVREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVE
MMAR_5015|M.marinum_M ------MSTDTTAVGVREIDAGILPNRYARGWHCLGVAKDFMDGKPHGVE
MUL_4089|M.ulcerans_Agy99 ------MSTDTTAVGVREIDAGILPNRYARGWHCLGVAKDFMDGKPHGVE
** *:* * *:****:***: : :* ** ::
MSMEG_2870|M.smegmatis_MC2_155 AFGGKLVVFRGEDGKINVLDSYCRHMGGDLSDGEVKGNEIACPFHDWRWG
TH_0323|M.thermoresistible__bu AFGGKLVVFRGGDGKINVLDAYCRHMGGDLSDGEVKGNEIACPFHDWRWG
Mvan_2869|M.vanbaalenii_PYR-1 AFGGKLVVFRGEDGKINVLDAYCRHMGGDLSDGEVKGNEIACPFHDWRWG
Mflv_4566|M.gilvum_PYR-GCK AFGQKLVVFRAEDGSINVLDSYCRHMGGDLSQGTVKGNEIACPFHDWRWG
MAV_3037|M.avium_104 AFGQKLVVFRGGDGAINVLDGYCRHMGGDLSRGEVKGNEIACPFHDWRWG
MAB_0080c|M.abscessus_ATCC_199 AFGQKLVVFRPAGGKVSVLDAYCRHMGGDLSQGEVKGDEIACPFHDWRWG
Mb3556|M.bovis_AF2122/97 AFGTKLVVFADSHGDLKVLDGYCRHMGGDLSEGTVKGDEVACPFHDWRWG
Rv3526|M.tuberculosis_H37Rv AFGTKLVVFADSHGDLKVLDGYCRHMGGDLSEGTVKGDEVACPFHDWRWG
MMAR_5015|M.marinum_M AFGTKLVVFTDSHGDLKILDSYCRHMGGDLSEGTIKGDEVACPFHDWRWG
MUL_4089|M.ulcerans_Agy99 AFGTKLVVFTDSHGDLKILDSYCRHMGGDLSEGTIKGDEVACPFHDWRWG
*** ***** * :.:**.********** * :**:*:**********
MSMEG_2870|M.smegmatis_MC2_155 GDGRCKQIPYSRRVPKLARTATWPTLEQDGMLFVWNDPEKNPPPPEVTIP
TH_0323|M.thermoresistible__bu GDGRCKKVPYSRRVPKLARTATWPTLEQDGMLFVWNDPENNPPPPDVTIP
Mvan_2869|M.vanbaalenii_PYR-1 GDGRCKQIPYSRRVPKLARTATWPTLDQDGMLFVWNDPEKKAPPAEVTIP
Mflv_4566|M.gilvum_PYR-GCK GDGRCKQVPYAKRVPRLARTQTWPTLEQDGMLFVWNDPQRKPPPDDVTIP
MAV_3037|M.avium_104 GDGRCKQVPYSRRTPRLARTRAWTTLQQDGMLFVWNDPEGNPPPPEVTIP
MAB_0080c|M.abscessus_ATCC_199 GDGRCKKVPYSRRTPKLARTATWITLEQDGMLFIWHDPQGNPPPEDVAIP
Mb3556|M.bovis_AF2122/97 GDGRCKLVPYARRTPRMARTRSWTTDVRSGLLFVWHDHEGNPPDPAVRIP
Rv3526|M.tuberculosis_H37Rv GDGRCKLVPYARRTPRMARTRSWTTDVRSGLLFVWHDHEGNPPDPAVRIP
MMAR_5015|M.marinum_M GDGRCKLVPYAKRTPRMARTRSWTTDVRGGLLFVWHDHEGNPPDPAVRIP
MUL_4089|M.ulcerans_Agy99 GDGRCKLVPYAKRTPRMARTRSWTTDVRGGLFFVWHDHEGNPPDPAVRIP
****** :**::*.*::*** :* * :.*::*:*:* : :.* * **
MSMEG_2870|M.smegmatis_MC2_155 RIEGVGTDRWTDWHWYTTVVH-TNCREIIDNVVDMAHFFYIHGGLPTGFK
TH_0323|M.thermoresistible__bu RIEGVGTDRWTDWHWYSTVVH-TNCREIIDNIVDMAHFFYIHGGLPTEFK
Mvan_2869|M.vanbaalenii_PYR-1 HIEGVGSDTWTDWHWYTTVVD-INCREIIDNVVDMAHFFYIHGGLPTGFK
Mflv_4566|M.gilvum_PYR-GCK RIEGATSDEWTDWHWYTTVVH-TNCREIIDNVVDMAHFFYIHGSLPTQFK
MAV_3037|M.avium_104 RIEGAGSDEWTDWHWYSTVVQ-SNCREIIDNVVDMAHFFYIHGSLPKQFK
MAB_0080c|M.abscessus_ATCC_199 RIEGATSPEWTDWHWYTTVVN-TNCREIIDNVVDMAHFFYVHGAVPTYFK
Mb3556|M.bovis_AF2122/97 EIPEAASDEWTDWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFK
Rv3526|M.tuberculosis_H37Rv EIPEAASDEWTDWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFK
MMAR_5015|M.marinum_M EIPEAASDDWTQWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFK
MUL_4089|M.ulcerans_Agy99 EIPEAASDDWTQWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFK
.* . : **:*:* ::. ***:****:.*******:* .:*. **
MSMEG_2870|M.smegmatis_MC2_155 NVFEGHIATQYYKS-EARPDLGSGEG-AKILGTTSVASYYGPSFMIDDLT
TH_0323|M.thermoresistible__bu NVFEGHVATQYYKS-EARPDLGSGEG-AKILGTTSVASYYGPSFMIDDLT
Mvan_2869|M.vanbaalenii_PYR-1 NVFEGHVATQYYKS-DARPDLGKGEG-AQILGTTSVASYYGPSFMIDELT
Mflv_4566|M.gilvum_PYR-GCK NIFEGHTATQFMSS-GGRPDLGQAEGGVKLLGTTSLAAYHGPSFMIDDLT
MAV_3037|M.avium_104 NIFEGHVATQYMNS-AGRPDIG-GQG-ARMLGTTSVASYWGPSFMIDDLT
MAB_0080c|M.abscessus_ATCC_199 NIFEGHIATQYMNTGEPRADLPIPEG-VQMTGQTSVASYYGPSFMIDDLT
Mb3556|M.bovis_AF2122/97 NVFEGHIASQYLHN-VGRPDVDDLGTSYGEAHLDSEASYFGPSFMINWLH
Rv3526|M.tuberculosis_H37Rv NVFEGHIASQYLHN-VGRPDVDDLGTSYGEAHLDSEASYFGPSFMINWLH
MMAR_5015|M.marinum_M NVFEGHIASQYLHN-VGRPDVDDLGTAYGEAHLDSEASYFGPSFMINWLH
MUL_4089|M.ulcerans_Agy99 NVFEGHIASQYLHN-VGRPDVDDLGTAYGEAHLDSEASYFGPSFMINWLH
*:**** *:*: . *.*: * *:* ******: *
MSMEG_2870|M.smegmatis_MC2_155 YHYEHGDQRTVLLNCHYPIDANSFVLQYGITVEMSDAVPHDVATQMAVAL
TH_0323|M.thermoresistible__bu YHYEHGDQRTVLINCHYPIDANSFVLQYGITVEISDTAPRDIAMQMAVAL
Mvan_2869|M.vanbaalenii_PYR-1 YHYQHGDQRTVLLNCHYPIDANSFVLQYGIIVEKSDALPAEAATQMAVAL
Mflv_4566|M.gilvum_PYR-GCK YHYEHGDTKTVLINCHYPIDANSFVLQYGIVVQKSADLPEDLAVQTAVAL
MAV_3037|M.avium_104 YHYEDADHQTVLINCHYPIDANSFVLQYGIIVKKSDALPDDLAMQTAIAL
MAB_0080c|M.abscessus_ATCC_199 YHFVGYDSNSILINCHYPIDANSFVLQYGIIVKKSAGLSDDDALAAAITL
Mb3556|M.bovis_AF2122/97 NRYGNYKSESILINCHYPVTQNSFVLQWGVIVEKPKGMSEEMTDKLSRVF
Rv3526|M.tuberculosis_H37Rv NRYGNYKSESILINCHYPVTQNSFVLQWGVIVEKPKGMSEEMTDKLSRVF
MMAR_5015|M.marinum_M NSYGGYKSESILINCHYPVTQDSFVLQWGVIVEKPKGMDEKMTDKLSRVF
MUL_4089|M.ulcerans_Agy99 NSYGGYKSESILINCHYPVTQDSFVLQWGVIVEKPKGMDEKMTDKLSRVF
: . .::*:*****: :*****:*: *: . . : : .:
MSMEG_2870|M.smegmatis_MC2_155 GDFVKMGFEQDVAIWKRKARIDNPLLCEEDGPVYQLRRWYEQFYVDVADV
TH_0323|M.thermoresistible__bu GDFVKMGFEQDVAIWKRKARIDNPLLCEEDGPVYQVRRWYEQFYVDVADV
Mvan_2869|M.vanbaalenii_PYR-1 GDFVKMGFEQDVAIWRRKARIDNPLLCEEDGPVYQLRRWYEQFYVDIADV
Mflv_4566|M.gilvum_PYR-GCK GDFVKMGFEQDVQIWRNKARIDNPLLVEEDGPVYQLRRWYEQFYVDVEDV
MAV_3037|M.avium_104 GDFVKLGFEQDVEIWRHKARIDNPLLVEEDGPVYQLRRWYQQFYVDVADV
MAB_0080c|M.abscessus_ATCC_199 GDWIKAGFEQDVQIWKNKARIDNPLLCEEDGPVYQLRRWYEQFYVDVADV
Mb3556|M.bovis_AF2122/97 TEGVSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQLRRWYEQFYVDVADI
Rv3526|M.tuberculosis_H37Rv TEGVSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQLRRWYEQFYVDVADI
MMAR_5015|M.marinum_M TEGVSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYEQFYVDAADV
MUL_4089|M.ulcerans_Agy99 TEGVSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYEQFYVDAADV
: :. ** *** **:.*:******* ****.***:****:***** *:
MSMEG_2870|M.smegmatis_MC2_155 TPDMVDRFEFEIDTTRPREAWLKEVQDNLAAG--------RLPRLVGVNK
TH_0323|M.thermoresistible__bu TPDMVDRFEFEIDTTRPREAWMKEVEDNIAAG--------RLPRLVGVNK
Mvan_2869|M.vanbaalenii_PYR-1 TPDMVNRFEFEIDTARPREAWMKEVEANLAAG--------RLPKLVGLTK
Mflv_4566|M.gilvum_PYR-GCK TPDMVDRFEFEIDTTRPRESWMKEVEDNIAAG--------RIPKLASGTT
MAV_3037|M.avium_104 QPDMVDRFEFELDTTRPYAAWMKEVEANLAAR--------A---------
MAB_0080c|M.abscessus_ATCC_199 TAEMTDRFEYEVDTTRPGEAWKAQVEENLAAM--------AGGAPS----
Mb3556|M.bovis_AF2122/97 KPEMVERFEIEVDTKRANEFWNAEVEKNLKSR--------EVSDDVPAEQ
Rv3526|M.tuberculosis_H37Rv KPEMVERFEIEVDTKRANEFWNAEVEKNLKSR--------EVSDDVPAEQ
MMAR_5015|M.marinum_M TPEMVERFEMEVDTTRANEFWRAEVQQNLETKKLQEQQAESVPDDVPAEQ
MUL_4089|M.ulcerans_Agy99 TPEMVERFEMEVDTTRANEFWRAEVQQNLETKKLQEQQAESVPDDVPAEQ
.:*.:*** *:** *. * :*: *: :
MSMEG_2870|M.smegmatis_MC2_155 -
TH_0323|M.thermoresistible__bu -
Mvan_2869|M.vanbaalenii_PYR-1 -
Mflv_4566|M.gilvum_PYR-GCK -
MAV_3037|M.avium_104 -
MAB_0080c|M.abscessus_ATCC_199 -
Mb3556|M.bovis_AF2122/97 H
Rv3526|M.tuberculosis_H37Rv H
MMAR_5015|M.marinum_M H
MUL_4089|M.ulcerans_Agy99 H