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STDTAGIREIDTGALPDRYARGWHCLGPVKNFTDGEPHGIEIFGTMLVVFADSQGELKVLDGYCRHMGGN LAQGTIKGDEVACPFHDWRWGGDGKCKLVPYAKRTPRLARTRAWHTDVRGGLLFVWHDHEGNPPQPEVRI PEIPQWSSGEWTDWKWNTMLIEGSNCREIIDNVTDMAHFFYIHFGLPTYFKNVFEGHVASQYLHNVGRPD INDMGTAYGDASLDSEASYFGPSFMINWLHNTYGDFKAESILINCHYPVSQDSFVLQWGVIVEKPQGLDD KTTEKLADAFTDGVSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYQQFYVDVADVTPEMTDRFEM EVDTTVANQKWNVEVEENLKAREAEKTEQPAT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1533 | - | - | 100% (383) | Rieske (2Fe-2S) domain-containing protein |
| M. gilvum PYR-GCK | Mflv_1546 | - | e-140 | 64.15% (357) | Rieske (2Fe-2S) domain-containing protein |
| M. gilvum PYR-GCK | Mflv_4566 | - | e-129 | 56.96% (381) | Rieske (2Fe-2S) domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3556 | - | 0.0 | 79.79% (376) | oxidoreductase |
| M. tuberculosis H37Rv | Rv3526 | - | 0.0 | 79.79% (376) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4173 | - | 1e-180 | 75.00% (388) | oxidoreductase |
| M. marinum M | MMAR_5015 | - | 0.0 | 79.27% (381) | oxidoreductase |
| M. avium 104 | MAV_0633 | - | 0.0 | 81.22% (378) | Rieske (2Fe-2S) domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_5925 | - | 0.0 | 89.24% (381) | Rieske (2Fe-2S) domain-containing protein |
| M. thermoresistible (build 8) | TH_0377 | - | 0.0 | 85.45% (385) | POSSIBLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_4089 | - | 0.0 | 79.00% (381) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5225 | - | 0.0 | 94.40% (375) | Rieske (2Fe-2S) domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3556|M.bovis_AF2122/97 MSTDTSGVG--VREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVEAFGT
Rv3526|M.tuberculosis_H37Rv MSTDTSGVG--VREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVEAFGT
MMAR_5015|M.marinum_M MSTDTTAVG--VREIDAGILPNRYARGWHCLGVAKDFMDGKPHGVEAFGT
MUL_4089|M.ulcerans_Agy99 MSTDTTAVG--VREIDAGILPNRYARGWHCLGVAKDFMDGKPHGVEAFGT
MAV_0633|M.avium_104 MATDTKPVG--IREIDPGALPTRYARGWHCLGVAKDFQDGKPHSIEAFGT
Mflv_1533|M.gilvum_PYR-GCK MSTDTAG----IREIDTGALPDRYARGWHCLGPVKNFTDGEPHGIEIFGT
Mvan_5225|M.vanbaalenii_PYR-1 MSTEASAGTAHIREIDTGALPDRYARGWHCLGPVKNFLDGKPHGIEIFGT
MSMEG_5925|M.smegmatis_MC2_155 MATETVG----IREIDTGALPDRYARGWHCLGPVKNFSDGKPHSVNIFGT
TH_0377|M.thermoresistible__bu VSTHTAGSSG-IREIDTGTLPDRYARGWHCLGPVENFLDGKPHGIRAFGT
MAB_4173|M.abscessus_ATCC_1997 MSTDTAGIG--VREIDVGELPTRYARGWHCLGVAESFRDGEPHAIDAFGT
::*.: :**** * ** ********** .:.: :*:**.: ***
Mb3556|M.bovis_AF2122/97 KLVVFADSHGDLKVLDGYCRHMGGDLSEGTVKGDEVACPFHDWRWGGDGR
Rv3526|M.tuberculosis_H37Rv KLVVFADSHGDLKVLDGYCRHMGGDLSEGTVKGDEVACPFHDWRWGGDGR
MMAR_5015|M.marinum_M KLVVFTDSHGDLKILDSYCRHMGGDLSEGTIKGDEVACPFHDWRWGGDGR
MUL_4089|M.ulcerans_Agy99 KLVVFTDSHGDLKILDSYCRHMGGDLSEGTIKGDEVACPFHDWRWGGDGR
MAV_0633|M.avium_104 KLVVFADSHGDIHVLDGYCRHMGGDLSEGTIKGDEVACPFHDWRWGGDGR
Mflv_1533|M.gilvum_PYR-GCK MLVVFADSQGELKVLDGYCRHMGGNLAQGTIKGDEVACPFHDWRWGGDGK
Mvan_5225|M.vanbaalenii_PYR-1 MLVVFADSQGELNVLDGYCRHMGGNLAQGEIKGDEVACPFHDWRWGGDGK
MSMEG_5925|M.smegmatis_MC2_155 KLVVFADSKGELNVLDAYCRHMGGDLSKGTVKGDEVACPFHDWRWGGDGK
TH_0377|M.thermoresistible__bu KLVVFADSSGELKILDAYCRHMGGDLSQGTIKGDEVACPFHDWRWGGDGK
MAB_4173|M.abscessus_ATCC_1997 KLVVFADTQGDIKVLDGYCRHMGGDLSQGSIKGDNVACPFHDWRWGGDGK
****:*: *::::**.*******:*::* :***:**************:
Mb3556|M.bovis_AF2122/97 CKLVPYARRTPRMARTRSWTTDVRSGLLFVWHDHEGNPPDPAVRIPEIPE
Rv3526|M.tuberculosis_H37Rv CKLVPYARRTPRMARTRSWTTDVRSGLLFVWHDHEGNPPDPAVRIPEIPE
MMAR_5015|M.marinum_M CKLVPYAKRTPRMARTRSWTTDVRGGLLFVWHDHEGNPPDPAVRIPEIPE
MUL_4089|M.ulcerans_Agy99 CKLVPYAKRTPRMARTRSWTTDVRGGLFFVWHDHEGNPPDPAVRIPEIPE
MAV_0633|M.avium_104 CKLVPYAKRTPKTARTRSWTTDVRGGLLFVWHDHENNPPDPAVRIPEIPE
Mflv_1533|M.gilvum_PYR-GCK CKLVPYAKRTPRLARTRAWHTDVRGGLLFVWHDHEGNPPQPEVRIPEIPQ
Mvan_5225|M.vanbaalenii_PYR-1 CKLVPYAKRTPRLARTRAWHTDVRGGLLFVWHDHEGNPPQPEVRIPEIPE
MSMEG_5925|M.smegmatis_MC2_155 CKLVPYAKRTPRLARTRSWHTDVRGGLLFVWHDHEGNPPQPEVRIPEIPE
TH_0377|M.thermoresistible__bu CKLVPYAKRTPRLARTRAWHTDVRGGLLFVWHDHEGNPPQPEVRIPEIPE
MAB_4173|M.abscessus_ATCC_1997 CKLVPYAKRTPKLARTRSWITDVKSGLLFVWHDAEGNGPTDDVEIPEIPE
*******:***: ****:* ***:.**:***** *.* * *.*****:
Mb3556|M.bovis_AF2122/97 AASDEWTDWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFE
Rv3526|M.tuberculosis_H37Rv AASDEWTDWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFE
MMAR_5015|M.marinum_M AASDDWTQWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFE
MUL_4089|M.ulcerans_Agy99 AASDDWTQWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFE
MAV_0633|M.avium_104 AHSDEWTDWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFE
Mflv_1533|M.gilvum_PYR-GCK WSSGEWTDWKWNTMLIEGSNCREIIDNVTDMAHFFYIHFGLPTYFKNVFE
Mvan_5225|M.vanbaalenii_PYR-1 WSSGEWTDWKWNTLLIEGSNCREIIDNVTDMAHFFYIHFGLPTYFKNVFE
MSMEG_5925|M.smegmatis_MC2_155 WHSGEWTDWKWNSMLIEGSNCREIIDNVTDMAHFFYIHFGLPTYFKNVFE
TH_0377|M.thermoresistible__bu AHSDEWTDWRWNSILIEGANCREIIDNVTDMAHFFYIHFGMPTYFKNVFE
MAB_4173|M.abscessus_ATCC_1997 YSDDGWTTWDWNTIVIEGSNCREIVDNVTDMAHFYYIHFGFPTYFKNVFE
.. ** * ** ::***:***:*:*********:*****:*********
Mb3556|M.bovis_AF2122/97 GHIASQYLHNVGRPDVDDLGTS--YGEAHLDSEASYFGPSFMINWLHNRY
Rv3526|M.tuberculosis_H37Rv GHIASQYLHNVGRPDVDDLGTS--YGEAHLDSEASYFGPSFMINWLHNRY
MMAR_5015|M.marinum_M GHIASQYLHNVGRPDVDDLGTA--YGEAHLDSEASYFGPSFMINWLHNSY
MUL_4089|M.ulcerans_Agy99 GHIASQYLHNVGRPDVDDLGTA--YGEAHLDSEASYFGPSFMINWLHNSY
MAV_0633|M.avium_104 GHIASQYLHNVGRPDVNDLGTS--YGEAHLDSEASYFGPSFMINWLHNSY
Mflv_1533|M.gilvum_PYR-GCK GHVASQYLHNVGRPDINDMGTA--YGDASLDSEASYFGPSFMINWLHNTY
Mvan_5225|M.vanbaalenii_PYR-1 GHIASQYLHNVGRPDVNDMGTA--YGEASLDSEASYFGPSFMINWLHNKY
MSMEG_5925|M.smegmatis_MC2_155 GHIASQYLHNVGRPDVNDLGTA--YGEAKLDSEASYFGPSFMINWLHNTY
TH_0377|M.thermoresistible__bu GHIASQYLHNVGRPDVGDLGTA--YGESHLDSEASYFGPSFMINWLHNTY
MAB_4173|M.abscessus_ATCC_1997 GHIASQYLRTVGRPDVQLGGSSQYTGEQILDSEASYFGPSFMINWLHNNY
**:*****:.*****: *:: *: ******************* *
Mb3556|M.bovis_AF2122/97 GNYKSESILINCHYPVTQNSFVLQWGVIVEKPKGMSEEMTDKLSRVFTEG
Rv3526|M.tuberculosis_H37Rv GNYKSESILINCHYPVTQNSFVLQWGVIVEKPKGMSEEMTDKLSRVFTEG
MMAR_5015|M.marinum_M GGYKSESILINCHYPVTQDSFVLQWGVIVEKPKGMDEKMTDKLSRVFTEG
MUL_4089|M.ulcerans_Agy99 GGYKSESILINCHYPVTQDSFVLQWGVIVEKPKGMDEKMTDKLSRVFTEG
MAV_0633|M.avium_104 GDYKAESILINCHYPVTQNSFVLQWGVIVEKPKGMDEEMTDKLSRVFTEG
Mflv_1533|M.gilvum_PYR-GCK GDFKAESILINCHYPVSQDSFVLQWGVIVEKPQGLDDKTTEKLADAFTDG
Mvan_5225|M.vanbaalenii_PYR-1 GDFKAESILINCHYPVTQDSFVLQWGVIVEKPKGLDDGTTQKLADAFTDG
MSMEG_5925|M.smegmatis_MC2_155 GEFKAESILINCHYPVTQDSFVLQWGVIVEKPKGLDDATTEKLADAFTEG
TH_0377|M.thermoresistible__bu GEFKAESILINCHYPVTQDSFVLQWGVIVEKPKGLDDETTQKLADAFTDG
MAB_4173|M.abscessus_ATCC_1997 GGYKAESILINCHYPIDQNSFVLQYGVIVQKPAGMDEKMTGKLSRAMTKG
* :*:**********: *:*****:****:** *:.: * **: .:*.*
Mb3556|M.bovis_AF2122/97 VSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQLRRWYEQFYVDVADIKPE
Rv3526|M.tuberculosis_H37Rv VSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQLRRWYEQFYVDVADIKPE
MMAR_5015|M.marinum_M VSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYEQFYVDAADVTPE
MUL_4089|M.ulcerans_Agy99 VSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYEQFYVDAADVTPE
MAV_0633|M.avium_104 VSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQLRRWYQQFYVDVADIEPE
Mflv_1533|M.gilvum_PYR-GCK VSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYQQFYVDVADVTPE
Mvan_5225|M.vanbaalenii_PYR-1 VSKGFMQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYQQFYVDVADVTPE
MSMEG_5925|M.smegmatis_MC2_155 VSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYQQFYVDVADITPD
TH_0377|M.thermoresistible__bu VSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYQQFYVDVADITPD
MAB_4173|M.abscessus_ATCC_1997 VGQGFLQDVEIWKNKTRIDNPLLVEEDGAVYQMRRWYSQFYVDKADVTPE
*.:**:*******:******************:****.***** **: *:
Mb3556|M.bovis_AF2122/97 MVERFEIEVDTKRANEFWNAEVEKNLKSR--------EVSDDVPAEQH--
Rv3526|M.tuberculosis_H37Rv MVERFEIEVDTKRANEFWNAEVEKNLKSR--------EVSDDVPAEQH--
MMAR_5015|M.marinum_M MVERFEMEVDTTRANEFWRAEVQQNLETKKLQEQQAESVPDDVPAEQH--
MUL_4089|M.ulcerans_Agy99 MVERFEMEVDTTRANEFWRAEVQQNLETKKLQEQQAESVPDDVPAEQH--
MAV_0633|M.avium_104 MVERFEIEVDTTRANEYWNAEVAQNLKAK---------ESEDVPAEQH--
Mflv_1533|M.gilvum_PYR-GCK MTDRFEMEVDTTVANQKWNVEVEENLKAR----------EAEKTEQPAT-
Mvan_5225|M.vanbaalenii_PYR-1 MTDRFEMEVDTTAAVQKWNVEVEENLKAR----------ETETQST----
MSMEG_5925|M.smegmatis_MC2_155 MTDRFEMEVDTTAAVEKWNIEVQENLKAQ----------AEAEKAEQSS-
TH_0377|M.thermoresistible__bu MTDRFEIEVDTTAAVEYWTKQVEENLARQ----------AEEKKAEKAGD
MAB_4173|M.abscessus_ATCC_1997 MTDRFELEIDTTKANEFWHGEVDENLQRQ---------ALEKEKAEQAAA
*.:***:*:**. * : * :* :** :
Mb3556|M.bovis_AF2122/97 ---------------
Rv3526|M.tuberculosis_H37Rv ---------------
MMAR_5015|M.marinum_M ---------------
MUL_4089|M.ulcerans_Agy99 ---------------
MAV_0633|M.avium_104 ---------------
Mflv_1533|M.gilvum_PYR-GCK ---------------
Mvan_5225|M.vanbaalenii_PYR-1 ---------------
MSMEG_5925|M.smegmatis_MC2_155 ---------------
TH_0377|M.thermoresistible__bu ARTENATRQGADQSS
MAB_4173|M.abscessus_ATCC_1997 ESGSHAEATQS----