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TRFARGWHCLGLADSFRDGAPHGINAFGTMLVVFADSRGNLAVLDGYCRHMGGNLAQGTIKGDEVACPFH DWRWGGDGRCTLVPYAKRTPRLARTRAWHTTEVNGQLLVWHDPEGSAPATELIPPTIEGYDEGRWSPWQW SSVLIEGAHCREIVDNNVDMAHFFYIHHAYPTYFKNVIEGHTASQFMESKPRPDFTPNPEKLWEGTYLRS EATYFGPAYMINWLHNDLAPEFTVEVALINCHYPVTHSSFMLQWGVAVQEMPALPADKAEKLASAMSRSF GEGFLEDVEIWKNKSPIENPLLTEEDGPVYQHRRWYHQFYVDAADVTADMTDRYEQEVDTTHANVLWQRE VDENMAARR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1546 | - | - | 100% (360) | Rieske (2Fe-2S) domain-containing protein |
| M. gilvum PYR-GCK | Mflv_1533 | - | e-140 | 64.15% (357) | Rieske (2Fe-2S) domain-containing protein |
| M. gilvum PYR-GCK | Mflv_4566 | - | e-118 | 55.19% (366) | Rieske (2Fe-2S) domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3556 | - | 1e-130 | 58.10% (358) | oxidoreductase |
| M. tuberculosis H37Rv | Rv3526 | - | 1e-130 | 58.10% (358) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3627c | - | 0.0 | 81.74% (356) | oxidoreductase |
| M. marinum M | MMAR_5015 | - | 1e-131 | 58.94% (358) | oxidoreductase |
| M. avium 104 | MAV_0633 | - | 1e-131 | 58.66% (358) | Rieske (2Fe-2S) domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_5925 | - | 1e-136 | 62.46% (357) | Rieske (2Fe-2S) domain-containing protein |
| M. thermoresistible (build 8) | TH_0377 | - | 1e-137 | 63.38% (355) | POSSIBLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_4089 | - | 1e-131 | 58.66% (358) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5211 | - | 0.0 | 90.83% (360) | Rieske (2Fe-2S) domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3556|M.bovis_AF2122/97 MSTDTSG-VGVREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVEAFGTK
Rv3526|M.tuberculosis_H37Rv MSTDTSG-VGVREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVEAFGTK
MMAR_5015|M.marinum_M MSTDTTA-VGVREIDAGILPNRYARGWHCLGVAKDFMDGKPHGVEAFGTK
MUL_4089|M.ulcerans_Agy99 MSTDTTA-VGVREIDAGILPNRYARGWHCLGVAKDFMDGKPHGVEAFGTK
MAV_0633|M.avium_104 MATDTKP-VGIREIDPGALPTRYARGWHCLGVAKDFQDGKPHSIEAFGTK
MSMEG_5925|M.smegmatis_MC2_155 MATETVG---IREIDTGALPDRYARGWHCLGPVKNFSDGKPHSVNIFGTK
TH_0377|M.thermoresistible__bu VSTHTAGSSGIREIDTGTLPDRYARGWHCLGPVENFLDGKPHGIRAFGTK
Mflv_1546|M.gilvum_PYR-GCK -------------------MTRFARGWHCLGLADSFRDGAPHGINAFGTM
Mvan_5211|M.vanbaalenii_PYR-1 ---MTD----VREIDTGSVMTRFARGWHCLGLADAFRDGRPHGVDAFGTM
MAB_3627c|M.abscessus_ATCC_199 ---MTDG--AIREIDSGAPMTRFARGWHCLGLAETFLDGQPHGIEAFGTK
*:******** .. : :* **.: ***
Mb3556|M.bovis_AF2122/97 LVVFADSHGDLKVLDGYCRHMGGDLSEGTVKGDEVACPFHDWRWGGDGRC
Rv3526|M.tuberculosis_H37Rv LVVFADSHGDLKVLDGYCRHMGGDLSEGTVKGDEVACPFHDWRWGGDGRC
MMAR_5015|M.marinum_M LVVFTDSHGDLKILDSYCRHMGGDLSEGTIKGDEVACPFHDWRWGGDGRC
MUL_4089|M.ulcerans_Agy99 LVVFTDSHGDLKILDSYCRHMGGDLSEGTIKGDEVACPFHDWRWGGDGRC
MAV_0633|M.avium_104 LVVFADSHGDIHVLDGYCRHMGGDLSEGTIKGDEVACPFHDWRWGGDGRC
MSMEG_5925|M.smegmatis_MC2_155 LVVFADSKGELNVLDAYCRHMGGDLSKGTVKGDEVACPFHDWRWGGDGKC
TH_0377|M.thermoresistible__bu LVVFADSSGELKILDAYCRHMGGDLSQGTIKGDEVACPFHDWRWGGDGKC
Mflv_1546|M.gilvum_PYR-GCK LVVFADSRGNLAVLDGYCRHMGGNLAQGTIKGDEVACPFHDWRWGGDGRC
Mvan_5211|M.vanbaalenii_PYR-1 LVVFADTGGSLRVLDGYCRHMGGNLAQGEIKGDEVACPFHDWRWGGDGRC
MAB_3627c|M.abscessus_ATCC_199 LVVFADSHGDIKVLDGYCRHMGGDLSQGTVKDDTVACPFHDWRWGGDGRC
****:*: *.: :**.*******:*::* :*.* **************:*
Mb3556|M.bovis_AF2122/97 KLVPYARRTPRMARTRSWTTDVRSGLLFVWHDHEGNPPDPAVRIPEIPEA
Rv3526|M.tuberculosis_H37Rv KLVPYARRTPRMARTRSWTTDVRSGLLFVWHDHEGNPPDPAVRIPEIPEA
MMAR_5015|M.marinum_M KLVPYAKRTPRMARTRSWTTDVRGGLLFVWHDHEGNPPDPAVRIPEIPEA
MUL_4089|M.ulcerans_Agy99 KLVPYAKRTPRMARTRSWTTDVRGGLFFVWHDHEGNPPDPAVRIPEIPEA
MAV_0633|M.avium_104 KLVPYAKRTPKTARTRSWTTDVRGGLLFVWHDHENNPPDPAVRIPEIPEA
MSMEG_5925|M.smegmatis_MC2_155 KLVPYAKRTPRLARTRSWHTDVRGGLLFVWHDHEGNPPQPEVRIPEIPEW
TH_0377|M.thermoresistible__bu KLVPYAKRTPRLARTRAWHTDVRGGLLFVWHDHEGNPPQPEVRIPEIPEA
Mflv_1546|M.gilvum_PYR-GCK TLVPYAKRTPRLARTRAWHTTEVNGQLLVWHDPEGSAPATELIPPTIEGY
Mvan_5211|M.vanbaalenii_PYR-1 KLVPYAKRTPRMARTRAWPTTEVNGQLLVWHDPERSSPPTELIPPTIAGY
MAB_3627c|M.abscessus_ATCC_199 TLVPYAKRTPKLARTRSWPTLEVNGQLLVWHDPEGSAPPAELTPPTIEGY
.*****:***: ****:* * .* ::**** * ..* . : * *
Mb3556|M.bovis_AF2122/97 ASDEWTDWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFEG
Rv3526|M.tuberculosis_H37Rv ASDEWTDWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFEG
MMAR_5015|M.marinum_M ASDDWTQWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFEG
MUL_4089|M.ulcerans_Agy99 ASDDWTQWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFEG
MAV_0633|M.avium_104 HSDEWTDWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFEG
MSMEG_5925|M.smegmatis_MC2_155 HSGEWTDWKWNSMLIEGSNCREIIDNVTDMAHFFYIHFGLPTYFKNVFEG
TH_0377|M.thermoresistible__bu HSDEWTDWRWNSILIEGANCREIIDNVTDMAHFFYIHFGMPTYFKNVFEG
Mflv_1546|M.gilvum_PYR-GCK DEGRWSPWQWSSVLIEGAHCREIVDNNVDMAHFFYIHHAYPTYFKNVIEG
Mvan_5211|M.vanbaalenii_PYR-1 DEGRWSPWQWSSILIEGAHCREIVDNNVDMAHFFYIHHAYPTYFKNVIEG
MAB_3627c|M.abscessus_ATCC_199 GEGKWSPWQWNSILIEGSHCREIVDNNVDMAHFFYIHHAYPTYFKNVIEG
.. *: *:*. :****::**:*:** .*********.. *******:**
Mb3556|M.bovis_AF2122/97 HIASQYLHNVGRPD-VDDLGTSYGEAHLDSEASYFGPSFMINWLHNRYG-
Rv3526|M.tuberculosis_H37Rv HIASQYLHNVGRPD-VDDLGTSYGEAHLDSEASYFGPSFMINWLHNRYG-
MMAR_5015|M.marinum_M HIASQYLHNVGRPD-VDDLGTAYGEAHLDSEASYFGPSFMINWLHNSYG-
MUL_4089|M.ulcerans_Agy99 HIASQYLHNVGRPD-VDDLGTAYGEAHLDSEASYFGPSFMINWLHNSYG-
MAV_0633|M.avium_104 HIASQYLHNVGRPD-VNDLGTSYGEAHLDSEASYFGPSFMINWLHNSYG-
MSMEG_5925|M.smegmatis_MC2_155 HIASQYLHNVGRPD-VNDLGTAYGEAKLDSEASYFGPSFMINWLHNTYG-
TH_0377|M.thermoresistible__bu HIASQYLHNVGRPD-VGDLGTAYGESHLDSEASYFGPSFMINWLHNTYG-
Mflv_1546|M.gilvum_PYR-GCK HTASQFMESKPRPDFTPNPEKLWEGTYLRSEATYFGPAYMINWLHNDLAP
Mvan_5211|M.vanbaalenii_PYR-1 HTASQFMESKPRPDFTANPEKLWDGTYLRSEATYFGPAYMINWLHNDLAP
MAB_3627c|M.abscessus_ATCC_199 QTASQFMESKPRPDYVPNPEKLWEGTGVRSEATYFGPAYMIDWIHNDLGP
: ***::.. *** . : . : : : ***:****::**:*:** .
Mb3556|M.bovis_AF2122/97 NYKSESILINCHYPVTQNSFVLQWGVIVEKPKGMSEEMTDKLSRVFTEGV
Rv3526|M.tuberculosis_H37Rv NYKSESILINCHYPVTQNSFVLQWGVIVEKPKGMSEEMTDKLSRVFTEGV
MMAR_5015|M.marinum_M GYKSESILINCHYPVTQDSFVLQWGVIVEKPKGMDEKMTDKLSRVFTEGV
MUL_4089|M.ulcerans_Agy99 GYKSESILINCHYPVTQDSFVLQWGVIVEKPKGMDEKMTDKLSRVFTEGV
MAV_0633|M.avium_104 DYKAESILINCHYPVTQNSFVLQWGVIVEKPKGMDEEMTDKLSRVFTEGV
MSMEG_5925|M.smegmatis_MC2_155 EFKAESILINCHYPVTQDSFVLQWGVIVEKPKGLDDATTEKLADAFTEGV
TH_0377|M.thermoresistible__bu EFKAESILINCHYPVTQDSFVLQWGVIVEKPKGLDDETTQKLADAFTDGV
Mflv_1546|M.gilvum_PYR-GCK EFTVEVALINCHYPVTHSSFMLQWGVAVQEMPALPADKAEKLASAMSRSF
Mvan_5211|M.vanbaalenii_PYR-1 DFTVEVALINCHYPVSHNSFMLQWGVAVQEMPGLPADKAAKLAAAMNRSF
MAB_3627c|M.abscessus_ATCC_199 GFTVEVALINCHYPVTHDSFVLQWGVAIQEMPDLPPDNARKLAAAMAKSF
:. * ********::.**:***** ::: : : **: .: ..
Mb3556|M.bovis_AF2122/97 SKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQLRRWYEQFYVDVADIKPEM
Rv3526|M.tuberculosis_H37Rv SKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQLRRWYEQFYVDVADIKPEM
MMAR_5015|M.marinum_M SKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYEQFYVDAADVTPEM
MUL_4089|M.ulcerans_Agy99 SKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYEQFYVDAADVTPEM
MAV_0633|M.avium_104 SKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQLRRWYQQFYVDVADIEPEM
MSMEG_5925|M.smegmatis_MC2_155 SKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYQQFYVDVADITPDM
TH_0377|M.thermoresistible__bu SKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYQQFYVDVADITPDM
Mflv_1546|M.gilvum_PYR-GCK GEGFLEDVEIWKNKSPIENPLLTEEDGPVYQHRRWYHQFYVDAADVTADM
Mvan_5211|M.vanbaalenii_PYR-1 GEGFLEDVEIWKNKSPIENPLLTEEDGPVYQHRRWYQQFYVDAADVTADM
MAB_3627c|M.abscessus_ATCC_199 GDGFLEDVEIWKNKTRIDNPLLTHEDGAVYQHRRWYEQFYVDLADVTSDM
..***:******:*: *:****..***.*** ****.***** **: .:*
Mb3556|M.bovis_AF2122/97 VERFEIEVDTKRANEFWNAEVEKNLKSR--------EVSDDVPAEQH---
Rv3526|M.tuberculosis_H37Rv VERFEIEVDTKRANEFWNAEVEKNLKSR--------EVSDDVPAEQH---
MMAR_5015|M.marinum_M VERFEMEVDTTRANEFWRAEVQQNLETKKLQEQQAESVPDDVPAEQH---
MUL_4089|M.ulcerans_Agy99 VERFEMEVDTTRANEFWRAEVQQNLETKKLQEQQAESVPDDVPAEQH---
MAV_0633|M.avium_104 VERFEIEVDTTRANEYWNAEVAQNLKAK---------ESEDVPAEQH---
MSMEG_5925|M.smegmatis_MC2_155 TDRFEMEVDTTAAVEKWNIEVQENLKAQ----------AEAEKAEQSS--
TH_0377|M.thermoresistible__bu TDRFEIEVDTTAAVEYWTKQVEENLARQ----------AEEKKAEKAGDA
Mflv_1546|M.gilvum_PYR-GCK TDRYEQEVDTTHANVLWQREVDENMAAR-------------R--------
Mvan_5211|M.vanbaalenii_PYR-1 TGRYEQEVDTTHANDLWQQEVERNMAAR-------------KPGSV----
MAB_3627c|M.abscessus_ATCC_199 TERFELEVDTTHAHGVWVHEVEENLVEH-------------AATASH---
. *:* ****. * * :* .*: :
Mb3556|M.bovis_AF2122/97 --------------
Rv3526|M.tuberculosis_H37Rv --------------
MMAR_5015|M.marinum_M --------------
MUL_4089|M.ulcerans_Agy99 --------------
MAV_0633|M.avium_104 --------------
MSMEG_5925|M.smegmatis_MC2_155 --------------
TH_0377|M.thermoresistible__bu RTENATRQGADQSS
Mflv_1546|M.gilvum_PYR-GCK --------------
Mvan_5211|M.vanbaalenii_PYR-1 --------------
MAB_3627c|M.abscessus_ATCC_199 --------------