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VNKAADRWSTGLPGLRSGMSTPMQGIGGLLSMSADAVKFLFRRPFQTSEFLLQSWFVARVSLAPTLLVAI PFTVLVSFTLNILLSELGAADLSGAGAAFGAVTQVGPMVTVLIVAGAGATAMCADLGSRTIREEIDALEV LGINPVQRLVTPRMLASGLVALLLNSLVVIIGIVGGYVFSIFVQGVNPGAFAAGITLLTGVPEVIISCVK AALFGLIAGLVACYRGLSISTGGAKAVGNAVNETVVYAFMALFVVNVVVTAIGIQMTSG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4540 | - | - | 100% (270) | hypothetical protein Mflv_4540 |
| M. gilvum PYR-GCK | Mflv_2506 | - | e-124 | 85.19% (270) | hypothetical protein Mflv_2506 |
| M. gilvum PYR-GCK | Mflv_1554 | - | 5e-94 | 71.06% (235) | hypothetical protein Mflv_1554 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3531c | yrbE4A | 2e-96 | 68.40% (250) | integral membrane protein YrbE4a |
| M. tuberculosis H37Rv | Rv3501c | yrbE4A | 2e-96 | 68.40% (250) | integral membrane protein YrbE4a |
| M. leprae Br4923 | MLBr_02587 | yrbE1A | 2e-85 | 60.56% (251) | hypothetical protein MLBr_02587 |
| M. abscessus ATCC 19977 | MAB_4155c | - | 3e-97 | 69.44% (252) | hypothetical protein MAB_4155c |
| M. marinum M | MMAR_4712 | - | 1e-126 | 86.99% (269) | hypothetical protein MMAR_4712 |
| M. avium 104 | MAV_0946 | - | 1e-126 | 85.61% (271) | TrnB1 protein |
| M. smegmatis MC2 155 | MSMEG_2853 | - | 1e-128 | 86.30% (270) | hypothetical protein MSMEG_2853 |
| M. thermoresistible (build 8) | TH_0393 | - | 1e-129 | 87.78% (270) | CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE4A |
| M. ulcerans Agy99 | MUL_4064 | yrbE4A | 4e-96 | 68.00% (250) | membrane protein YrbE4A |
| M. vanbaalenii PYR-1 | Mvan_2849 | - | 1e-137 | 93.33% (270) | hypothetical protein Mvan_2849 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3531c|M.bovis_AF2122/97 -------------------------MIQQ--LAVPARAVGGFFEMSMDTA
MUL_4064|M.ulcerans_Agy99 MKASADPGLALGKHWRRRRLGRGTELIQQ--LAVPARAVGGFFEMSIDTA
Rv3501c|M.tuberculosis_H37Rv -------------------------MIQQ--LAVPARAVGGFFEMSMDTA
MAB_4155c|M.abscessus_ATCC_199 -------------------------MKQQ--LAAPARAVGGFVSMSLATF
Mflv_4540|M.gilvum_PYR-GCK ----------MVNKAADRWSTGLPGLRSG--MSTPMQGIGGLLSMSADAV
Mvan_2849|M.vanbaalenii_PYR-1 ----------MVDKAADRWSSGLPALGAG--MAAPMQGVGGLLSMSADAV
MSMEG_2853|M.smegmatis_MC2_155 ----------MVNEAADRWSPGLRVLRGG--TSTTLEAIGGLFAMSSDAV
TH_0393|M.thermoresistible__bu ----------MVNKAVDRWSTGLPLPAGG--TAGTLRAVGGLFSMSVDAV
MMAR_4712|M.marinum_M ----------MANRAADRWTPGITFGRG----SKPMQAVGGLFAMSADAI
MAV_0946|M.avium_104 ----------MADLRAERWSTGLPALRLKVDVSGAMQAVGALFAMSADAV
MLBr_02587|M.leprae_Br4923 -------------MTTETRSSLVEYAHTK--LQTPLVLVGGFFRMLVLTG
. :*.:. * :
Mb3531c|M.bovis_AF2122/97 RAAFRRPFQFREFLDQTWMVARVSLVPTLLVSIPFTVLVAFTLNILLREI
MUL_4064|M.ulcerans_Agy99 RAAFRRPFQFREFLDQTWMVARVSLVPTLLVSIPFTVLVAFTLNILLREI
Rv3501c|M.tuberculosis_H37Rv RAAFRRPFQFREFLDQTWMVARVSLVPTLLVSIPFTVLVAFTLNILLREI
MAB_4155c|M.abscessus_ATCC_199 RNIFRRPFQGQEFLDQTWFIARVSLLPTLLVAIPFTVLVAFTLNILLREI
Mflv_4540|M.gilvum_PYR-GCK KFLFRRPFQTSEFLLQSWFVARVSLAPTLLVAIPFTVLVSFTLNILLSEL
Mvan_2849|M.vanbaalenii_PYR-1 KFLFRRPFQGREFLEQSWFVARVSLMPTLLVAIPFTVLVSFTLNILLREL
MSMEG_2853|M.smegmatis_MC2_155 RFAFRRPFQGREFLEQSWFVARVSLAPTLLVAIPFTVLVSFTLNILLREL
TH_0393|M.thermoresistible__bu RFAFRRPFQGREFLEQSWFVARVALLPTLLVAIPFTVLVSFTLNILLREL
MMAR_4712|M.marinum_M KFAFRRPFQWREFLEQSWFVARVAMLPTLLVAIPFTVLVSFTLNILLREL
MAV_0946|M.avium_104 KYLFRRPFQWREFLEQSWFVARVSLAPTLLVAIPFTVLVSFTLNILLREL
MLBr_02587|M.leprae_Br4923 KALFRRPFQWREFILQCWFIMRVAFLPTVMVSIPLTVLLIFTLNVLLAQF
: ****** **: * *:: **:: **::*:**:***: ****:** ::
Mb3531c|M.bovis_AF2122/97 GAADLSGAGTAFGTITQLGPVVTVLVVAGAGATAICADLGARTIREEIDA
MUL_4064|M.ulcerans_Agy99 GAADLSGAGTAFGTITQLGPVVTVLVVAGAGATAICADLGARTIREEIDA
Rv3501c|M.tuberculosis_H37Rv GAADLSGAGTAFGTITQLGPVVTVLVVAGAGATAICADLGARTIREEIDA
MAB_4155c|M.abscessus_ATCC_199 GAADLSGAATAFGTVTQLGPVVTVLVVAGAGATAICADLGARTIREEIDA
Mflv_4540|M.gilvum_PYR-GCK GAADLSGAGAAFGAVTQVGPMVTVLIVAGAGATAMCADLGSRTIREEIDA
Mvan_2849|M.vanbaalenii_PYR-1 GAADLSGAGAAFGAVTQVGPMVTVLIVAGAGATAMCADLGSRTIREEIDA
MSMEG_2853|M.smegmatis_MC2_155 GAADLSGAGAAFGAVTQVGPMVTVLIVAGAGATAMCADLGSRTIRDEIDA
TH_0393|M.thermoresistible__bu GAADLSGAGAAFGAVTQVGPMVTVLIVAGAGATAMCADLGSRTIRDEVDA
MMAR_4712|M.marinum_M GAADLSGAGAAFGAVTQVGPLVTVLIVAGAGATAMCADLGSRTIREEIDA
MAV_0946|M.avium_104 GAADLSGAGAAFGAVTQLGPLVTVLIVAGAGATAMCADLGSRTIREEIDA
MLBr_02587|M.leprae_Br4923 SAADLSGAGAAIGAVTQLGPLTTVLVVAGAGSTSICADLGARTIREEIDA
.*******.:*:*::**:**:.***:*****:*::*****:****:*:**
Mb3531c|M.bovis_AF2122/97 MRVLGIDPIQRLVVPRVLASTLVALLLNGLVCAIGLSGGYAFSVFLQGVN
MUL_4064|M.ulcerans_Agy99 MRVLGIDPIQRLVVPRVLASTVVALLLNGLVCAIGLSGGYAFSVFLQGVN
Rv3501c|M.tuberculosis_H37Rv MRVLGIDPIQRLVVPRVLASTLVALLLNGLVCAIGLSGGYAFSVFLQGVN
MAB_4155c|M.abscessus_ATCC_199 MQVLGIDPIQRLVVPRVLASTFVALLLNGLVCAIGMVGGYVFSVFLQGVN
Mflv_4540|M.gilvum_PYR-GCK LEVLGINPVQRLVTPRMLASGLVALLLNSLVVIIGIVGGYVFSIFVQGVN
Mvan_2849|M.vanbaalenii_PYR-1 LEVLGINPVQRLVTPRMLASGLVALLLNSLVVIIGILGGYFFSIFIQGVN
MSMEG_2853|M.smegmatis_MC2_155 MEVLGINPIQRLVTPRILASGLVALLLNSLVVIIGILGGYTFSVFIQGVN
TH_0393|M.thermoresistible__bu LEVLGINPVQRLVTPRMLASGLVALLLNSLVVIIGILGGYTFSVFVQDVN
MMAR_4712|M.marinum_M MEVLGINPVQRLVTPRMLASGLVALLLNSLVVIIGIVGGYVFSVFVQDVN
MAV_0946|M.avium_104 MEVLGINPIQRLVTPRMLASGLVAFLLNSLVVIIGVLGGYVFSVFVQDVN
MLBr_02587|M.leprae_Br4923 MEVLGIDPIHRLVVPRVLAATLVATLLNGLVITVGLVGGYLFGVYLQNVS
:.****:*::***.**:**: .** ***.** :*: *** *.:::*.*.
Mb3531c|M.bovis_AF2122/97 PGAFINGLTVLTGLRELILAEIKALLFGVMAGLVGCYRGLTVK-GGPKGV
MUL_4064|M.ulcerans_Agy99 PGAFINGLTVLTGLRELILAEIKALLFGVMAGLVGCYRGLTVK-GGPKGV
Rv3501c|M.tuberculosis_H37Rv PGAFINGLTVLTGLRELILAEIKALLFGVMAGLVGCYRGLTVK-GGPKGV
MAB_4155c|M.abscessus_ATCC_199 PGAFINGLTVLTGLGELMISEVKAFLFGIFAGLVGCYRGLTVK-GGPKGV
Mflv_4540|M.gilvum_PYR-GCK PGAFAAGITLLTGVPEVIISCVKAALFGLIAGLVACYRGLSISTGGAKAV
Mvan_2849|M.vanbaalenii_PYR-1 PGAFAAGITLLTGVPEVIISCVKAALFGLIAGLVACYRGLSISGGGAKAV
MSMEG_2853|M.smegmatis_MC2_155 PGAFAAGITLLTGVPEVIISCIKAMLFGFIAGMVACFRGLTIAGGGAKAV
TH_0393|M.thermoresistible__bu PGAFAAGITLLTGVPEVIISCVKAALFGLIAGLVACYRGLTISGGGAKAV
MMAR_4712|M.marinum_M PGAFAAGITLLTGVPEVIISCVKAALFGLIAGLVACYRGLTISGGGAKAV
MAV_0946|M.avium_104 PGAFAAGITLLTGVPEVVISCIKAALFGLIAGLVACYRGLSITGGGAKAV
MLBr_02587|M.leprae_Br4923 GGAYLATLTTITGLPEVVIATVKAATFGLIAGLVGCYRGLIVR-GGSNGL
**: :* :**: *:::: :** **.:**:*.*:*** : **.:.:
Mb3531c|M.bovis_AF2122/97 GNAVNETVVYAFICLFVINVVMTAIGVRISAQ-
MUL_4064|M.ulcerans_Agy99 GNAVNETVVYAFICLFVINVVMTAIGVRISAR-
Rv3501c|M.tuberculosis_H37Rv GNAVNETVVYAFICLFVINVVMTAIGVRISAQ-
MAB_4155c|M.abscessus_ATCC_199 GDAVNETVVYAFICLFVINVVMTAIGVRVLVKH
Mflv_4540|M.gilvum_PYR-GCK GNAVNETVVYAFMALFVVNVVVTAIGIQMTSG-
Mvan_2849|M.vanbaalenii_PYR-1 GNAVNETVVYAFMALFVVNVVVTAIGIRMTSG-
MSMEG_2853|M.smegmatis_MC2_155 GNAVNETVVYAFMALFVVNVVVTAIGIRMTTG-
TH_0393|M.thermoresistible__bu GNAVNETVVYAFMALFVVNVVVTAIGIRMTAG-
MMAR_4712|M.marinum_M GNAVNETVVYAFMSLFVVNVVVTAIGIRMSAK-
MAV_0946|M.avium_104 GNAVNETVVYAFMSLFVVNVVVTAIGIKMTAK-
MLBr_02587|M.leprae_Br4923 GAAVNETVVLCVVALYAVNVVLTTIGVRFGTGH
* ******* ..:.*:.:***:*:**::.