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ANRAADRWTPGITFGRGSKPMQAVGGLFAMSADAIKFAFRRPFQWREFLEQSWFVARVAMLPTLLVAIPF TVLVSFTLNILLRELGAADLSGAGAAFGAVTQVGPLVTVLIVAGAGATAMCADLGSRTIREEIDAMEVLG INPVQRLVTPRMLASGLVALLLNSLVVIIGIVGGYVFSVFVQDVNPGAFAAGITLLTGVPEVIISCVKAA LFGLIAGLVACYRGLTISGGGAKAVGNAVNETVVYAFMSLFVVNVVVTAIGIRMSAK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4712 | - | - | 100% (268) | hypothetical protein MMAR_4712 |
| M. marinum M | MMAR_4989 | yrbE4A | 7e-97 | 72.69% (238) | membrane protein YrbE4A |
| M. marinum M | MMAR_0410 | yrbE1A | 2e-88 | 63.93% (244) | integral membrane protein YrbE1A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3531c | yrbE4A | 1e-101 | 72.58% (248) | integral membrane protein YrbE4a |
| M. gilvum PYR-GCK | Mflv_2506 | - | 1e-129 | 88.39% (267) | hypothetical protein Mflv_2506 |
| M. tuberculosis H37Rv | Rv3501c | yrbE4A | 1e-101 | 72.58% (248) | integral membrane protein YrbE4a |
| M. leprae Br4923 | MLBr_02587 | yrbE1A | 2e-87 | 63.93% (244) | hypothetical protein MLBr_02587 |
| M. abscessus ATCC 19977 | MAB_4155c | - | 2e-98 | 72.18% (248) | hypothetical protein MAB_4155c |
| M. avium 104 | MAV_0946 | - | 1e-129 | 87.13% (272) | TrnB1 protein |
| M. smegmatis MC2 155 | MSMEG_2853 | - | 1e-128 | 86.19% (268) | hypothetical protein MSMEG_2853 |
| M. thermoresistible (build 8) | TH_0393 | - | 1e-130 | 88.48% (269) | CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE4A |
| M. ulcerans Agy99 | MUL_4064 | yrbE4A | 1e-101 | 70.00% (260) | membrane protein YrbE4A |
| M. vanbaalenii PYR-1 | Mvan_2849 | - | 1e-129 | 87.73% (269) | hypothetical protein Mvan_2849 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3531c|M.bovis_AF2122/97 -------------------------MIQQ---LAVPARAVGGFFEMSMDT
MUL_4064|M.ulcerans_Agy99 MKASADPGLALGKHWRRRRLGRGTELIQQ---LAVPARAVGGFFEMSIDT
Rv3501c|M.tuberculosis_H37Rv -------------------------MIQQ---LAVPARAVGGFFEMSMDT
MAB_4155c|M.abscessus_ATCC_199 -------------------------MKQQ---LAAPARAVGGFVSMSLAT
MMAR_4712|M.marinum_M -----------MANRAADRWTPGITFGRG----SKPMQAVGGLFAMSADA
MAV_0946|M.avium_104 -----------MADLRAERWSTGLPALRLKVDVSGAMQAVGALFAMSADA
MSMEG_2853|M.smegmatis_MC2_155 -----------MVNEAADRWSPGLRVLRG--GTSTTLEAIGGLFAMSSDA
TH_0393|M.thermoresistible__bu -----------MVNKAVDRWSTGLPLPAG--GTAGTLRAVGGLFSMSVDA
Mvan_2849|M.vanbaalenii_PYR-1 -----------MVDKAADRWSSGLPALGA--GMAAPMQGVGGLLSMSADA
Mflv_2506|M.gilvum_PYR-GCK -----------MAVKGPERWTTGISLPN---GLSGAMQAVGGFFSMALDA
MLBr_02587|M.leprae_Br4923 --------------MTTETRSSLVEYAHT--KLQTPLVLVGGFFRMLVLT
. :*.:. * :
Mb3531c|M.bovis_AF2122/97 ARAAFRRPFQFREFLDQTWMVARVSLVPTLLVSIPFTVLVAFTLNILLRE
MUL_4064|M.ulcerans_Agy99 ARAAFRRPFQFREFLDQTWMVARVSLVPTLLVSIPFTVLVAFTLNILLRE
Rv3501c|M.tuberculosis_H37Rv ARAAFRRPFQFREFLDQTWMVARVSLVPTLLVSIPFTVLVAFTLNILLRE
MAB_4155c|M.abscessus_ATCC_199 FRNIFRRPFQGQEFLDQTWFIARVSLLPTLLVAIPFTVLVAFTLNILLRE
MMAR_4712|M.marinum_M IKFAFRRPFQWREFLEQSWFVARVAMLPTLLVAIPFTVLVSFTLNILLRE
MAV_0946|M.avium_104 VKYLFRRPFQWREFLEQSWFVARVSLAPTLLVAIPFTVLVSFTLNILLRE
MSMEG_2853|M.smegmatis_MC2_155 VRFAFRRPFQGREFLEQSWFVARVSLAPTLLVAIPFTVLVSFTLNILLRE
TH_0393|M.thermoresistible__bu VRFAFRRPFQGREFLEQSWFVARVALLPTLLVAIPFTVLVSFTLNILLRE
Mvan_2849|M.vanbaalenii_PYR-1 VKFLFRRPFQGREFLEQSWFVARVSLMPTLLVAIPFTVLVSFTLNILLRE
Mflv_2506|M.gilvum_PYR-GCK VRFVFVRPFQWREFLEQSWFVAKVSMAPTLLVAIPFTVLVSFTLNILLRE
MLBr_02587|M.leprae_Br4923 GKALFRRPFQWREFILQCWFIMRVAFLPTVMVSIPLTVLLIFTLNVLLAQ
: * **** :**: * *:: :*:: **::*:**:***: ****:** :
Mb3531c|M.bovis_AF2122/97 IGAADLSGAGTAFGTITQLGPVVTVLVVAGAGATAICADLGARTIREEID
MUL_4064|M.ulcerans_Agy99 IGAADLSGAGTAFGTITQLGPVVTVLVVAGAGATAICADLGARTIREEID
Rv3501c|M.tuberculosis_H37Rv IGAADLSGAGTAFGTITQLGPVVTVLVVAGAGATAICADLGARTIREEID
MAB_4155c|M.abscessus_ATCC_199 IGAADLSGAATAFGTVTQLGPVVTVLVVAGAGATAICADLGARTIREEID
MMAR_4712|M.marinum_M LGAADLSGAGAAFGAVTQVGPLVTVLIVAGAGATAMCADLGSRTIREEID
MAV_0946|M.avium_104 LGAADLSGAGAAFGAVTQLGPLVTVLIVAGAGATAMCADLGSRTIREEID
MSMEG_2853|M.smegmatis_MC2_155 LGAADLSGAGAAFGAVTQVGPMVTVLIVAGAGATAMCADLGSRTIRDEID
TH_0393|M.thermoresistible__bu LGAADLSGAGAAFGAVTQVGPMVTVLIVAGAGATAMCADLGSRTIRDEVD
Mvan_2849|M.vanbaalenii_PYR-1 LGAADLSGAGAAFGAVTQVGPMVTVLIVAGAGATAMCADLGSRTIREEID
Mflv_2506|M.gilvum_PYR-GCK LGAADLSGAGAAFGAVTQVGPLVTVLIVAGAGATAMCADLGSRTIREEID
MLBr_02587|M.leprae_Br4923 FSAADLSGAGAAIGAVTQLGPLTTVLVVAGAGSTSICADLGARTIREEID
:.*******.:*:*::**:**:.***:*****:*::*****:****:*:*
Mb3531c|M.bovis_AF2122/97 AMRVLGIDPIQRLVVPRVLASTLVALLLNGLVCAIGLSGGYAFSVFLQGV
MUL_4064|M.ulcerans_Agy99 AMRVLGIDPIQRLVVPRVLASTVVALLLNGLVCAIGLSGGYAFSVFLQGV
Rv3501c|M.tuberculosis_H37Rv AMRVLGIDPIQRLVVPRVLASTLVALLLNGLVCAIGLSGGYAFSVFLQGV
MAB_4155c|M.abscessus_ATCC_199 AMQVLGIDPIQRLVVPRVLASTFVALLLNGLVCAIGMVGGYVFSVFLQGV
MMAR_4712|M.marinum_M AMEVLGINPVQRLVTPRMLASGLVALLLNSLVVIIGIVGGYVFSVFVQDV
MAV_0946|M.avium_104 AMEVLGINPIQRLVTPRMLASGLVAFLLNSLVVIIGVLGGYVFSVFVQDV
MSMEG_2853|M.smegmatis_MC2_155 AMEVLGINPIQRLVTPRILASGLVALLLNSLVVIIGILGGYTFSVFIQGV
TH_0393|M.thermoresistible__bu ALEVLGINPVQRLVTPRMLASGLVALLLNSLVVIIGILGGYTFSVFVQDV
Mvan_2849|M.vanbaalenii_PYR-1 ALEVLGINPVQRLVTPRMLASGLVALLLNSLVVIIGILGGYFFSIFIQGV
Mflv_2506|M.gilvum_PYR-GCK AMEVLGINPVQRLVTPRMLASGLVALLLNSLVVIIGILGGYFFSIFVQDV
MLBr_02587|M.leprae_Br4923 AMEVLGIDPIHRLVVPRVLAATLVATLLNGLVITVGLVGGYLFGVYLQNV
*:.****:*::***.**:**: .** ***.** :*: *** *.:::*.*
Mb3531c|M.bovis_AF2122/97 NPGAFINGLTVLTGLRELILAEIKALLFGVMAGLVGCYRGLTVKGG-PKG
MUL_4064|M.ulcerans_Agy99 NPGAFINGLTVLTGLRELILAEIKALLFGVMAGLVGCYRGLTVKGG-PKG
Rv3501c|M.tuberculosis_H37Rv NPGAFINGLTVLTGLRELILAEIKALLFGVMAGLVGCYRGLTVKGG-PKG
MAB_4155c|M.abscessus_ATCC_199 NPGAFINGLTVLTGLGELMISEVKAFLFGIFAGLVGCYRGLTVKGG-PKG
MMAR_4712|M.marinum_M NPGAFAAGITLLTGVPEVIISCVKAALFGLIAGLVACYRGLTISGGGAKA
MAV_0946|M.avium_104 NPGAFAAGITLLTGVPEVVISCIKAALFGLIAGLVACYRGLSITGGGAKA
MSMEG_2853|M.smegmatis_MC2_155 NPGAFAAGITLLTGVPEVIISCIKAMLFGFIAGMVACFRGLTIAGGGAKA
TH_0393|M.thermoresistible__bu NPGAFAAGITLLTGVPEVIISCVKAALFGLIAGLVACYRGLTISGGGAKA
Mvan_2849|M.vanbaalenii_PYR-1 NPGAFAAGITLLTGVPEVIISCVKAALFGLIAGLVACYRGLSISGGGAKA
Mflv_2506|M.gilvum_PYR-GCK NPGAFAAGITLLTGVPEVIISCVKAALFGLIAGLVACYRGLTITGGGAKA
MLBr_02587|M.leprae_Br4923 SGGAYLATLTTITGLPEVVIATVKAATFGLIAGLVGCYRGLIVRGG-SNG
. **: :* :**: *:::: :** **.:**:*.*:*** : ** .:.
Mb3531c|M.bovis_AF2122/97 VGNAVNETVVYAFICLFVINVVMTAIGVRISAQ-
MUL_4064|M.ulcerans_Agy99 VGNAVNETVVYAFICLFVINVVMTAIGVRISAR-
Rv3501c|M.tuberculosis_H37Rv VGNAVNETVVYAFICLFVINVVMTAIGVRISAQ-
MAB_4155c|M.abscessus_ATCC_199 VGDAVNETVVYAFICLFVINVVMTAIGVRVLVKH
MMAR_4712|M.marinum_M VGNAVNETVVYAFMSLFVVNVVVTAIGIRMSAK-
MAV_0946|M.avium_104 VGNAVNETVVYAFMSLFVVNVVVTAIGIKMTAK-
MSMEG_2853|M.smegmatis_MC2_155 VGNAVNETVVYAFMALFVVNVVVTAIGIRMTTG-
TH_0393|M.thermoresistible__bu VGNAVNETVVYAFMALFVVNVVVTAIGIRMTAG-
Mvan_2849|M.vanbaalenii_PYR-1 VGNAVNETVVYAFMALFVVNVVVTAIGIRMTSG-
Mflv_2506|M.gilvum_PYR-GCK VGNAVNETVVYAFMALFVINVVVTAIGIRMTTG-
MLBr_02587|M.leprae_Br4923 LGAAVNETVVLCVVALYAVNVVLTTIGVRFGTGH
:* ******* ..:.*:.:***:*:**::.