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AFGDTDDDAQLRAAWHEFCDRLKTAGDLAFKDTSPPNALQRADAFRYLTQNLGQAYDLALETKNTRYPMI HPFCGPTRKLGGDNADFVYLQAWIDGASTYRIAGDRGTARFLNFTVQGPRPEKDVYYGADHPNLHEPFGD TPEANIAGDDLVTEPDGSFELYVGGPRRESNWLPTTPGSRKLFMRQGFDSWTERSAQFSIERIDMDEPRP APTPQDLIASMRWAGDFLTGVMTDWPDRELQIGSLFGEPEPNVFPGARFAGTAEQRDARRGRLIVTMPWH LEPDEALIFEFADDGEFWMLTNMGAFWNSMDYLYRPVSHTPSRSAIDADGRVRMVMSHNDPGVHNWIDTQ QFSEGYLTMRVIGSRQLPEVSTRVVAAAELDTVLPPDTRRVTPEERVVHLHERFDAIRRRYRI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4400 | - | - | 100% (414) | hypothetical protein Mflv_4400 |
| M. gilvum PYR-GCK | Mflv_2496 | - | e-133 | 56.90% (413) | hypothetical protein Mflv_2496 |
| M. gilvum PYR-GCK | Mflv_4414 | - | 2e-21 | 27.81% (374) | hypothetical protein Mflv_4414 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3561c | - | 2e-19 | 25.94% (347) | hypothetical protein Mb3561c |
| M. tuberculosis H37Rv | Rv3531c | - | 2e-19 | 25.94% (347) | hypothetical protein Rv3531c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4179c | - | 4e-28 | 29.11% (371) | hypothetical protein MAB_4179c |
| M. marinum M | MMAR_0906 | - | 1e-28 | 30.37% (438) | hypothetical protein MMAR_0906 |
| M. avium 104 | MAV_0063 | - | 1e-138 | 59.08% (413) | hypothetical protein MAV_0063 |
| M. smegmatis MC2 155 | MSMEG_5932 | - | 2e-19 | 27.36% (329) | hypothetical protein MSMEG_5932 |
| M. thermoresistible (build 8) | TH_3890 | - | 8e-23 | 26.76% (370) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0659 | - | 3e-29 | 30.59% (438) | hypothetical protein MUL_0659 |
| M. vanbaalenii PYR-1 | Mvan_4829 | - | 9e-23 | 24.54% (379) | hypothetical protein Mvan_4829 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3561c|M.bovis_AF2122/97 ----------------------MYSDPLREAIAEAEQLVAAAPHIET---
Rv3531c|M.tuberculosis_H37Rv ----------------------MYSDPLREAIAEAEQLVAAAPHIET---
MSMEG_5932|M.smegmatis_MC2_155 ----------------------MYSQPLVDAIAEAERLVAAAPFIES---
Mvan_4829|M.vanbaalenii_PYR-1 MRYFIRNIDHSGPILEHMSEVKMYVQEFLDRIAAAERLVREAPHVES---
MAB_4179c|M.abscessus_ATCC_199 ----------------------MYSEAFTAAIVEAEELIVAAPHIET---
MMAR_0906|M.marinum_M -----------MSAETSQASLHAAWTDMIDALTRARDAVDSAELHAPPVT
MUL_0659|M.ulcerans_Agy99 -----------MSAETSQASLHAAWTDMIDALTRARDAVDSAELHAPPVT
Mflv_4400|M.gilvum_PYR-GCK ---------MAFGDTDDDAQLRAAWHEFCDRLKTAGDLAFKDTSPPN---
MAV_0063|M.avium_104 -------MNMAFGDGPHDAALRAAWTEFCARLQRAGERAFKDHNPAS---
TH_3890|M.thermoresistible__bu -------------------------------MTGTATAVLAPPGNIG---
: :
Mb3561c|M.bovis_AF2122/97 EADLLEGLQYLAGCIAGCMHLAFDY-ERDHPFLQSGTGPFTKMGLDNPDT
Rv3531c|M.tuberculosis_H37Rv EADLLEGLQYLAGCIAGCMHLAFDY-ERDHPFLQSGTGPFTKMGLDNPDT
MSMEG_5932|M.smegmatis_MC2_155 EADLTEGLQYLAGCVSGCLHLAFDY-DRDHPFLQSGTGPFTKMGLDNPDT
Mvan_4829|M.vanbaalenii_PYR-1 EADLLEGLQYLAGCIAACTRLAFDY-DRDHPFLHSGTGPFTKMALDNPDT
MAB_4179c|M.abscessus_ATCC_199 EADLLEGLQYLAQGIAACTHMAFHT-DRDHPFLLSGTGPFTKMGLDNPDT
MMAR_0906|M.marinum_M AAGLADGYGYLLGFVFSGIERAFGE-NPDFPYFRRAIQPLDKATIDNADA
MUL_0659|M.ulcerans_Agy99 AAGLADGYGYLLGFVFSGIERALGE-NPDFPYFRRAIQPLDKATIDNADA
Mflv_4400|M.gilvum_PYR-GCK ALQRADAFRYLTQNLGQAYDLALETKNTRYPMIHPFCGPTRKLGGDNADF
MAV_0063|M.avium_104 GPHRVDAFRFLTQNLGQAFDLALETRDANYPVLHSFCGPTRKLGGDCADF
TH_3890|M.thermoresistible__bu -AATPEGDNIAEMMALAQAQLLQQAADLVRPVWVPFLSKTIRSAGANADT
:. : * : .*
Mb3561c|M.bovis_AF2122/97 LYFGTRLQANRDYVVSGRRGTTTDLSFQLLGG--EYTDYN--------VP
Rv3531c|M.tuberculosis_H37Rv LYFGTRLQANRDYVVSGRRGTTTDLSFQLLGG--EYTDYN--------VP
MSMEG_5932|M.smegmatis_MC2_155 LYFGTRVQPGHEYVVTGKRGTTTDLSFQVLGG--EYTDDN--------VP
Mvan_4829|M.vanbaalenii_PYR-1 LYFGTWLQGGHEYVLTGRRGTTTDLSFQLLGG--EYTEDN--------VP
MAB_4179c|M.abscessus_ATCC_199 LYFGARVSGEYEYVVTGKRGTTTDLSFQVLGGG-DYTDKN--------VP
MMAR_0906|M.marinum_M LYLSAPIDGAQSYRVTGRFVGPKPPQYLIFEAHTDYAGDTG--GLAELMP
MUL_0659|M.ulcerans_Agy99 LYLSAPIDGAQSYRVTGRFVGPKPPQYLIFEAHIDYAGDTG--GLAELMP
Mflv_4400|M.gilvum_PYR-GCK VYLQAWIDGASTYRIAGDRGTARFLNFTVQGPRPEKDVYYGADHPNLHEP
MAV_0063|M.avium_104 TYQQAWIDGRSTYRITGTRGTSRFFNVTVQGRRTP-------GEGVLHEP
TH_3890|M.thermoresistible__bu TYGVALLEPGGSYRISGRRGTVVFADLLVGAGLLGVVERQ--------QP
* : :. * ::* . : *
Mb3561c|M.bovis_AF2122/97 AS---QAAFDDRELDIAADGSFEWRLRPS-------------------AP
Rv3531c|M.tuberculosis_H37Rv AS---QAAFDDRELDIAADGSFEWRLRPS-------------------AP
MSMEG_5932|M.smegmatis_MC2_155 AS---QAAFDDRELDIAEDGTFEWRITPT-------------------SP
Mvan_4829|M.vanbaalenii_PYR-1 DN---QFAFDDRELDLAVDGSFEWRFTPN-------------------SD
MAB_4179c|M.abscessus_ATCC_199 GS---AIAFDDREIHIDSDGSFEVRFGPAPADDSR-----PNYFTLGPGP
MMAR_0906|M.marinum_M GGRVVTGALDTADLAVGEDGRFEILLGPRRPGEHTGNFIATRTPDGTATA
MUL_0659|M.ulcerans_Agy99 GGRVVTGALDTADLAVGEDGRFEILLGPRRPGEHTGNFIATRTPDGTATA
Mflv_4400|M.gilvum_PYR-GCK FGDTPEANIAGDDLVTEPDGSFELYVGGPRRE--------SNWLPTTPGS
MAV_0063|M.avium_104 FGDTPQANLFGQQLRVGADGRFELYVGGPERG--------HNWLPTTPES
TH_3890|M.thermoresistible__bu NVG----VVDFTDLDLGDDDTVELILSAERPAGYDG-----HWFRLDPTA
. :: *. .* .
Mb3561c|M.bovis_AF2122/97 GQLVIREVYGDWSQQRG-TLAIARLDTVGTAPPPLTRELMEKRYATAGSQ
Rv3531c|M.tuberculosis_H37Rv GQLVIREVYGDWSQQRG-TLAIARLDTVGTAPPPLTRELMEKRYATAGSQ
MSMEG_5932|M.smegmatis_MC2_155 SQLVIREVYNDWSAQRG-HLAIARTDTAGTAPPPLTKELIEKRYAVAGKQ
Mvan_4829|M.vanbaalenii_PYR-1 AQLVVREVYNDWSAQRG-TIAIARTDSTGTAPRTLTPELIAIRYAAAGKH
MAB_4179c|M.abscessus_ATCC_199 AQLVMREVYSDWREQRG-SLAIARVDTAGTAPAPLTKEQIEKRYASAGKQ
MMAR_0906|M.marinum_M RFLIARILFHDWEHEMSPDLHIVQIGKQGAQPEPADPAVVAQNMRRLGTI
MUL_0659|M.ulcerans_Agy99 RFLIARILFHDWEHEMSPDLHIVQIGKQGAQPEPADPAVVAQNMRRLGTI
Mflv_4400|M.gilvum_PYR-GCK RKLFMRQGFDSWTERSA-QFSIERIDMDEPRPAPTPQDLIAS-MRWAGDF
MAV_0063|M.avium_104 RKLFIRQGFDSWDEAPA-QLRIERVDMTVPKPLPTPGEMVEA-MRWAGDF
TH_3890|M.thermoresistible__bu DHVWLRQYFYDWETERPWSVTIERLDVAPTDPPKP-----ALRDVEINGF
: * : .* . * : . . * .
Mb3561c|M.bovis_AF2122/97 LVNRVKTWLQFPQWFYLN-----------IPVNTMVAPRLT----PGGLA
Rv3531c|M.tuberculosis_H37Rv LVNRVKTWLQFPQWFYLN-----------IPVNTMVAPRLT----PGGLA
MSMEG_5932|M.smegmatis_MC2_155 LVQRVKTWLQFPQWFYNN-----------LPVNTMVAPRLT----PGGLA
Mvan_4829|M.vanbaalenii_PYR-1 LTRRIRTWLSFPQWFYLN-----------VPVNTLTAPRIT----PGGLA
MAB_4179c|M.abscessus_ATCC_199 LVNRVKTWLQFPKWFYDN-----------LPVNTMTEPRLT----PGGLA
MMAR_0906|M.marinum_M VENQMRFWNEFYDVVLEAHGDKNGDGFTLMPRNSLNEPALANLAMGGGQS
MUL_0659|M.ulcerans_Agy99 VENQMRFWNEFYDVVLEAHGDKNGDGFTLMPRNSLNEPALANLAMGGGQS
Mflv_4400|M.gilvum_PYR-GCK LTGVMTDWPDRELQIGSLFGEP---EPNVFPGARFAGTAEQ----RDARR
MAV_0063|M.avium_104 VTGLMSDWPEYPFRHGGVDAE----NPNTFP----RAAATD----ADGKR
TH_3890|M.thermoresistible__bu VDRYVSMWQSHVAAMADRG-----------YVNRLETVGLP---DTTGMV
: : * . .
Mb3561c|M.bovis_AF2122/97 TQYSSAGHFELRPGQALVITVPV-SDAPYLGFQLGSMWYISLDYINHQTS
Rv3531c|M.tuberculosis_H37Rv TQYSSAGHFELRPGQALVITVPV-SDAPYLGFQLGSMWYISLDYINHQTS
MSMEG_5932|M.smegmatis_MC2_155 TQYSSVGHFDLRPDQAMVITLPV-TDAPYLGFQLGSLWYISLDYINHQTS
Mvan_4829|M.vanbaalenii_PYR-1 TQYSSVGHFDLGPGRAMVITLPA-SDAPYLGFQLGSMWYISLDYINHQTS
MAB_4179c|M.abscessus_ATCC_199 TQFSSVGHYDLADDQAMIITVPK-SDAPYQGFQLGSLWYISLDYINHQTS
MMAR_0906|M.marinum_M TNVYCGGVYDLRADEALLVEVVVPVPPAYMGFHLSNLWGESLDYANHACS
MUL_0659|M.ulcerans_Agy99 TNVYCGGVYDLRADEALLVEVVVPVPPAYMGFHLSNLWGESLDYANHACS
Mflv_4400|M.gilvum_PYR-GCK GRLIVTMPWHLEPDEALIFEFAD--DGEFWMLTNMGAFWNSMDYLYRPVS
MAV_0063|M.avium_104 GRAAANMYWELAPDEALIVEFDA--HPGLWMFTNMGVFFNSMDYLYRPVS
TH_3890|M.thermoresistible__bu AQSYFQGVYEIAEDEALLLEVRPPRRCRYWSVQLTDDRYISLDWMWRQTS
. :.: ..*::. . . . *:*: : *
Mb3561c|M.bovis_AF2122/97 LNASQAQADPDGKVRIVVAEQNPGVTNWVETLGHRRGFLQFRWQRVSREL
Rv3531c|M.tuberculosis_H37Rv LNASQAQADPDGKVRIVVAEQNPGVTNWVETLGHRRGFLQFRWQRVSREL
MSMEG_5932|M.smegmatis_MC2_155 LNGTQAQEDPDGKIRIVVSDANPGVTNWCETLGHRKGYLQFRWQRLSRAL
Mvan_4829|M.vanbaalenii_PYR-1 LNGTQAQVDPDGMIRIVVAHESPGIANWVETLGHRRGYLQFRWQRTSRKL
MAB_4179c|M.abscessus_ATCC_199 LNSSQAQIDPDGNIRMVVSNTNPGVTNWIETLGHRRAYLQFRWQRADRQL
MMAR_0906|M.marinum_M LNGFQSEPDADARIRYVIADTDPGVPNWLDTAGRLGGFLTLRWTYCD-PP
MUL_0659|M.ulcerans_Agy99 LNGFQSEPDADARMRYVIADTDPGVPNWLDTAGRLGGFLTLRWTYCD-PP
Mflv_4400|M.gilvum_PYR-GCK HTPSRSAIDADGRVRMVMSHNDPGVHNWIDTQQFSEGYLTMRVIGSR---
MAV_0063|M.avium_104 YTPSRTTVDGDGRIRLVMAHRDPGVHNWLDTQGFERGNLTYRHMLEG---
TH_3890|M.thermoresistible__bu LNGHQARLDPDGVFRAVISHRDPGVHNWLDAAGWTRGTILGRWNRAD---
. :: * *. .* *::. .**: ** :: . : *
Mb3561c|M.bovis_AF2122/97 TEADGPTVELVDFDAIPAALPHYQHNKISEDDWRARIALRQRQIATRMLG
Rv3531c|M.tuberculosis_H37Rv TEADGPTVELVDFDAIPAALPHYQHNKISEDDWRARIALRQRQIATRMLG
MSMEG_5932|M.smegmatis_MC2_155 TEADGPTVEVVDIDQVPEKLPYHESNKISEADWRARIALRQQQIQNRMVG
Mvan_4829|M.vanbaalenii_PYR-1 TAAEGPIAEVVDFDAIPSRLPYFGHNTISNDDFRTRIALRQNQIANRMVA
MAB_4179c|M.abscessus_ATCC_199 TPADGPTVEVVAVGDIPAKLPHYSQNQISEEGWRSRIAERQTAIGARMLG
MMAR_0906|M.marinum_M SELPKASAVKVPLASVRQHLPADTR-TVSVEERRRQISVRQEHVQRRYRQ
MUL_0659|M.ulcerans_Agy99 SELPKASAVKVPLASVRQHLPADTR-TVSVEERRRQISVRQEHVQRRYRQ
Mflv_4400|M.gilvum_PYR-GCK -QLPEVSTRVVAAAELDTVLPPDTR-RVTPEERVVHLHERFDAIRRRYRI
MAV_0063|M.avium_104 -EPAVLDTRVVEHDELLDALPKDTV-MVTPSQRADAMWKRFRGIRRRYVL
TH_3890|M.thermoresistible__bu -ANPVPSVKLVDFADLPGFLPADVP-RITSDERRAQLRARAAAAQRMG--
. * : ** :: : *
Mb3561c|M.bovis_AF2122/97 -
Rv3531c|M.tuberculosis_H37Rv -
MSMEG_5932|M.smegmatis_MC2_155 -
Mvan_4829|M.vanbaalenii_PYR-1 -
MAB_4179c|M.abscessus_ATCC_199 -
MMAR_0906|M.marinum_M Y
MUL_0659|M.ulcerans_Agy99 Y
Mflv_4400|M.gilvum_PYR-GCK -
MAV_0063|M.avium_104 -
TH_3890|M.thermoresistible__bu -