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MSAETSQASLHAAWTDMIDALTRARDAVDSAELHAPPVTAAGLADGYGYLLGFVFSGIERAFGENPDFPY FRRAIQPLDKATIDNADALYLSAPIDGAQSYRVTGRFVGPKPPQYLIFEAHTDYAGDTGGLAELMPGGRV VTGALDTADLAVGEDGRFEILLGPRRPGEHTGNFIATRTPDGTATARFLIARILFHDWEHEMSPDLHIVQ IGKQGAQPEPADPAVVAQNMRRLGTIVENQMRFWNEFYDVVLEAHGDKNGDGFTLMPRNSLNEPALANLA MGGGQSTNVYCGGVYDLRADEALLVEVVVPVPPAYMGFHLSNLWGESLDYANHACSLNGFQSEPDADARI RYVIADTDPGVPNWLDTAGRLGGFLTLRWTYCDPPSELPKASAVKVPLASVRQHLPADTRTVSVEERRRQ ISVRQEHVQRRYRQY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0906 | - | - | 100% (435) | hypothetical protein MMAR_0906 |
| M. marinum M | MMAR_5019 | - | 7e-35 | 28.34% (427) | hypothetical protein MMAR_5019 |
| M. marinum M | MMAR_0221 | - | 7e-13 | 25.08% (299) | hypothetical protein MMAR_0221 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3561c | - | 5e-36 | 28.33% (420) | hypothetical protein Mb3561c |
| M. gilvum PYR-GCK | Mflv_1529 | - | 1e-35 | 27.62% (420) | hypothetical protein Mflv_1529 |
| M. tuberculosis H37Rv | Rv3531c | - | 5e-36 | 28.33% (420) | hypothetical protein Rv3531c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4179c | - | 3e-37 | 28.47% (418) | hypothetical protein MAB_4179c |
| M. avium 104 | MAV_0629 | - | 4e-36 | 28.24% (425) | hypothetical protein MAV_0629 |
| M. smegmatis MC2 155 | MSMEG_5932 | - | 3e-37 | 27.10% (417) | hypothetical protein MSMEG_5932 |
| M. thermoresistible (build 8) | TH_0374 | - | 5e-36 | 28.16% (419) | HYPOTHETICAL PROTEIN Rv3531c |
| M. ulcerans Agy99 | MUL_0659 | - | 0.0 | 99.31% (435) | hypothetical protein MUL_0659 |
| M. vanbaalenii PYR-1 | Mvan_5229 | - | 4e-35 | 27.00% (437) | hypothetical protein Mvan_5229 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3561c|M.bovis_AF2122/97 ------------MYSDPLREAIAEAEQLVAAAPHIET---EADLLEGLQY
Rv3531c|M.tuberculosis_H37Rv ------------MYSDPLREAIAEAEQLVAAAPHIET---EADLLEGLQY
MAV_0629|M.avium_104 ------------MFSDPLTSAIAEAENLVAAAPHIET---EADLLEGLQY
TH_0374|M.thermoresistible__bu ------------MYSQPLLDAIAEAERIVTEAPHIET---EADLLEGLHY
Mflv_1529|M.gilvum_PYR-GCK ------------MFAQPLADAIAEAEELVSAAPFIES---EADLLEGLQY
Mvan_5229|M.vanbaalenii_PYR-1 MTPDRTRSSFGAVFTQPLAEAIAEAEKLVAAAPFIES---EADLLEGLQY
MSMEG_5932|M.smegmatis_MC2_155 ------------MYSQPLVDAIAEAERLVAAAPFIES---EADLTEGLQY
MAB_4179c|M.abscessus_ATCC_199 ------------MYSEAFTAAIVEAEELIVAAPHIET---EADLLEGLQY
MMAR_0906|M.marinum_M -MSAETSQASLHAAWTDMIDALTRARDAVDSAELHAPPVTAAGLADGYGY
MUL_0659|M.ulcerans_Agy99 -MSAETSQASLHAAWTDMIDALTRARDAVDSAELHAPPVTAAGLADGYGY
: *:..*. : * . *.* :* *
Mb3561c|M.bovis_AF2122/97 LAGCIAGCMHLAFDYERDHPFLQSGTGPFTKMGLDNPDTLYFGTRLQANR
Rv3531c|M.tuberculosis_H37Rv LAGCIAGCMHLAFDYERDHPFLQSGTGPFTKMGLDNPDTLYFGTRLQANR
MAV_0629|M.avium_104 LAGCISACIHLAVDYERDHPFLQSGTGPFTKMGLDNPDTLYFGTRVHAGY
TH_0374|M.thermoresistible__bu LAGCISACIHLAFDYERDHPFLQSGTGPFTKMGLDNPDTLYFGTRVLPGH
Mflv_1529|M.gilvum_PYR-GCK LAGCIAACTHVAFDYDRDHPFLHSGTGPFTKMGLDNPDTMYFGTRVQPGH
Mvan_5229|M.vanbaalenii_PYR-1 LAGCVAACTHVAFDYDRDHPFLHSGTGPFTKMGLDNPDTMYFGTRVQPGH
MSMEG_5932|M.smegmatis_MC2_155 LAGCVSGCLHLAFDYDRDHPFLQSGTGPFTKMGLDNPDTLYFGTRVQPGH
MAB_4179c|M.abscessus_ATCC_199 LAQGIAACTHMAFHTDRDHPFLLSGTGPFTKMGLDNPDTLYFGARVSGEY
MMAR_0906|M.marinum_M LLGFVFSGIERAFGENPDFPYFRRAIQPLDKATIDNADALYLSAPIDGAQ
MUL_0659|M.ulcerans_Agy99 LLGFVFSGIERALGENPDFPYFRRAIQPLDKATIDNADALYLSAPIDGAQ
* : . . *. : *.*:: . *: * :**.*::*:.: :
Mb3561c|M.bovis_AF2122/97 DYVVSGRRGTTTDLSFQLLGG--EYTDYN------VPAS---QAAFDDRE
Rv3531c|M.tuberculosis_H37Rv DYVVSGRRGTTTDLSFQLLGG--EYTDYN------VPAS---QAAFDDRE
MAV_0629|M.avium_104 DYVVTGRRGTTTDLSFQLLGG--EYTDDN------VPAS---QAAFDDRE
TH_0374|M.thermoresistible__bu EYVVTGTRGTTTDLSFQLLGG--EYTDEG------VPES---QAAFDDRE
Mflv_1529|M.gilvum_PYR-GCK EYVVTGRRGTTTDVSFQLLGG--EYTDEV------VPDS---DTAFDDRK
Mvan_5229|M.vanbaalenii_PYR-1 EYVVTGRRGTTTDVSFQLLGG--EYTDEV------VPDS---ETAFDDRK
MSMEG_5932|M.smegmatis_MC2_155 EYVVTGKRGTTTDLSFQVLGG--EYTDDN------VPAS---QAAFDDRE
MAB_4179c|M.abscessus_ATCC_199 EYVVTGKRGTTTDLSFQVLGGG-DYTDKN------VPGS---AIAFDDRE
MMAR_0906|M.marinum_M SYRVTGRFVGPKPPQYLIFEAHTDYAGDTGGLAELMPGGRVVTGALDTAD
MUL_0659|M.ulcerans_Agy99 SYRVTGRFVGPKPPQYLIFEAHIDYAGDTGGLAELMPGGRVVTGALDTAD
.* *:* .. .: :: . :*:. :* . *:* .
Mb3561c|M.bovis_AF2122/97 LDIAADGSFEWRLRPS-------------------APGQLVIREVYGDWS
Rv3531c|M.tuberculosis_H37Rv LDIAADGSFEWRLRPS-------------------APGQLVIREVYGDWS
MAV_0629|M.avium_104 LDIAPDGSFEWRVRPT-------------------SNGQLVIREVYGDWA
TH_0374|M.thermoresistible__bu LDIGEDGRFEWRFTPE-------------------QPSQLVIREVYGDWS
Mflv_1529|M.gilvum_PYR-GCK LDIAADGTFEWRFTPA-------------------VPSQLVIREVYNDWS
Mvan_5229|M.vanbaalenii_PYR-1 LDIAADGTFEWRFTPK-------------------VPSQLVIREVYNDWS
MSMEG_5932|M.smegmatis_MC2_155 LDIAEDGTFEWRITPT-------------------SPSQLVIREVYNDWS
MAB_4179c|M.abscessus_ATCC_199 IHIDSDGSFEVRFGPAPADDSR-----PNYFTLGPGPAQLVMREVYSDWR
MMAR_0906|M.marinum_M LAVGEDGRFEILLGPRRPGEHTGNFIATRTPDGTATARFLIARILFHDWE
MUL_0659|M.ulcerans_Agy99 LAVGEDGRFEILLGPRRPGEHTGNFIATRTPDGTATARFLIARILFHDWE
: : ** ** . * *: * :: **
Mb3561c|M.bovis_AF2122/97 QQRG-TLAIARLDTVGTAPPPLTRELMEKRYATAGSQLVNRVKTWLQFPQ
Rv3531c|M.tuberculosis_H37Rv QQRG-TLAIARLDTVGTAPPPLTRELMEKRYATAGSQLVNRVKTWLQFPQ
MAV_0629|M.avium_104 AQRG-TLAIAREDTAGTAPPPLTRETIEKRYATAGKQLVNRVKTWLQFPQ
TH_0374|M.thermoresistible__bu QQRG-TIAIARTDTAGTAPPPPTRRTIEKRYAVAGRQLVQRVKTWLQFPQ
Mflv_1529|M.gilvum_PYR-GCK AQRG-TFAIARTDTAGTAPPPLTRELIEKRYTVAGKQLVQRVKTWLQFPQ
Mvan_5229|M.vanbaalenii_PYR-1 AQRG-TFAIARTDTAGTAPPPLTRELIEKRYAVAGKQLVQRVKTWLQFPQ
MSMEG_5932|M.smegmatis_MC2_155 AQRG-HLAIARTDTAGTAPPPLTKELIEKRYAVAGKQLVQRVKTWLQFPQ
MAB_4179c|M.abscessus_ATCC_199 EQRG-SLAIARVDTAGTAPAPLTKEQIEKRYASAGKQLVNRVKTWLQFPK
MMAR_0906|M.marinum_M HEMSPDLHIVQIGKQGAQPEPADPAVVAQNMRRLGTIVENQMRFWNEFYD
MUL_0659|M.ulcerans_Agy99 HEMSPDLHIVQIGKQGAQPEPADPAVVAQNMRRLGTIVENQMRFWNEFYD
: . : *.: .. *: * * : :. * : :::: * :* .
Mb3561c|M.bovis_AF2122/97 WFYLNI-----------PVNTMVAPRLT----PGGLATQYSSAGHFELRP
Rv3531c|M.tuberculosis_H37Rv WFYLNI-----------PVNTMVAPRLT----PGGLATQYSSAGHFELRP
MAV_0629|M.avium_104 WFYFNI-----------PVNTMVAPRLT----PGGLATQYSSAGHYELRP
TH_0374|M.thermoresistible__bu WFYFNI-----------PVNTMVPPRLT----PGGLSTQYSSAGHYELEP
Mflv_1529|M.gilvum_PYR-GCK WFYNDS-----------PPNTMVAPRLT----PGGLATQYSSAGQFDLAE
Mvan_5229|M.vanbaalenii_PYR-1 WFYNDT-----------QPNSMVAPRLT----PGGLATQYSSAGQFDLAE
MSMEG_5932|M.smegmatis_MC2_155 WFYNNL-----------PVNTMVAPRLT----PGGLATQYSSVGHFDLRP
MAB_4179c|M.abscessus_ATCC_199 WFYDNL-----------PVNTMTEPRLT----PGGLATQFSSVGHYDLAD
MMAR_0906|M.marinum_M VVLEAHGDKNGDGFTLMPRNSLNEPALANLAMGGGQSTNVYCGGVYDLRA
MUL_0659|M.ulcerans_Agy99 VVLEAHGDKNGDGFTLMPRNSLNEPALANLAMGGGQSTNVYCGGVYDLRA
. *:: * *: ** :*: . * ::*
Mb3561c|M.bovis_AF2122/97 GQALVITVPV-SDAPYLGFQLGSMWYISLDYINHQTSLNASQAQADPDGK
Rv3531c|M.tuberculosis_H37Rv GQALVITVPV-SDAPYLGFQLGSMWYISLDYINHQTSLNASQAQADPDGK
MAV_0629|M.avium_104 DQALLITIPV-TDAPYLGFQLGSLWYISLDYINHQTSLNNTQAQADPDGK
TH_0374|M.thermoresistible__bu DQAMIITVPV-SDAPYLGFQLGSLWYISLDYINHQTSLNATQAQADPDGR
Mflv_1529|M.gilvum_PYR-GCK DQALIITLPV-TDAPYLGFQLGSLWYISLDYINHQTSLNGTQAQADPDDK
Mvan_5229|M.vanbaalenii_PYR-1 DQALIITLPV-TDAPYLGFQLGSLWYISLDYINHQTSLNGTQAQADPDGM
MSMEG_5932|M.smegmatis_MC2_155 DQAMVITLPV-TDAPYLGFQLGSLWYISLDYINHQTSLNGTQAQEDPDGK
MAB_4179c|M.abscessus_ATCC_199 DQAMIITVPK-SDAPYQGFQLGSLWYISLDYINHQTSLNSSQAQIDPDGN
MMAR_0906|M.marinum_M DEALLVEVVVPVPPAYMGFHLSNLWGESLDYANHACSLNGFQSEPDADAR
MUL_0659|M.ulcerans_Agy99 DEALLVEVVVPVPPAYMGFHLSNLWGESLDYANHACSLNGFQSEPDADAR
.:*::: : ..* **:*..:* **** ** *** *:: *.*
Mb3561c|M.bovis_AF2122/97 VRIVVAEQNPGVTNWVETLGHRRGFLQFRWQRVSRELTEADGPTVELVDF
Rv3531c|M.tuberculosis_H37Rv VRIVVAEQNPGVTNWVETLGHRRGFLQFRWQRVSRELTEADGPTVELVDF
MAV_0629|M.avium_104 VRIVVAEQNPGVTNWVETVGHRKGFLQFRWQRVSRQLTEADGPTVELVDF
TH_0374|M.thermoresistible__bu IRIVVSEANPGVTNWVETLGHRRGIMQFRWQRVSRPLTEADGPTVEVVDF
Mflv_1529|M.gilvum_PYR-GCK IRIVVSDRNPGVTNWVETLGHRKGFLQFRWQRVSREMTAADGPTVELVHV
Mvan_5229|M.vanbaalenii_PYR-1 IRIVVADRNPGVTNWVETLGHRKGFLQFRWQRVSRELTPADGPTVELVDI
MSMEG_5932|M.smegmatis_MC2_155 IRIVVSDANPGVTNWCETLGHRKGYLQFRWQRLSRALTEADGPTVEVVDI
MAB_4179c|M.abscessus_ATCC_199 IRMVVSNTNPGVTNWIETLGHRRAYLQFRWQRADRQLTPADGPTVEVVAV
MMAR_0906|M.marinum_M IRYVIADTDPGVPNWLDTAGRLGGFLTLRWTYCD-PPSELPKASAVKVPL
MUL_0659|M.ulcerans_Agy99 MRYVIADTDPGVPNWLDTAGRLGGFLTLRWTYCD-PPSELPKASAVKVPL
:* *::: :***.** :* *: . : :** . : .:. * .
Mb3561c|M.bovis_AF2122/97 DAIPAALPHYQHNKISEDDWRARIALRQRQIATRMLG-
Rv3531c|M.tuberculosis_H37Rv DAIPAALPHYQHNKISEDDWRARIALRQRQIATRMLG-
MAV_0629|M.avium_104 DAVPAKLPYYEHNKISDDEWRARIALRQQQIAARMLG-
TH_0374|M.thermoresistible__bu DQVPAALPYYESNRISEEAWRARIAQRQIQIANRMLG-
Mflv_1529|M.gilvum_PYR-GCK DDVASALPYHDSNTISEEDWRARIALRQKQIGERMVG-
Mvan_5229|M.vanbaalenii_PYR-1 DKVAAALPYYESNTISEQDWRARIALRQKQIGERMVG-
MSMEG_5932|M.smegmatis_MC2_155 DQVPEKLPYHESNKISEADWRARIALRQQQIQNRMVG-
MAB_4179c|M.abscessus_ATCC_199 GDIPAKLPHYSQNQISEEGWRSRIAERQTAIGARMLG-
MMAR_0906|M.marinum_M ASVRQHLPADTR-TVSVEERRRQISVRQEHVQRRYRQY
MUL_0659|M.ulcerans_Agy99 ASVRQHLPADTR-TVSVEERRRQISVRQEHVQRRYRQY
: ** :* * :*: ** : *