For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MAYGDGPDDVALRRAWETFCYQVKAAGQQIFKEHNPASELHRVDALRFLTQNLGQAFDLALETRDTRYPG MHAFCGPTRKLGGDCADFTYQQAWIDGDSVYRIHGERGTARFFNITVQGPRPDGPGVLHEPFGDVPEASL AGAELAVDHDGTFEVFLGGAPRASNWLPTTAGSRKLFVRQGFDSWDEIPARIAIERVDMAEPKPLPTAQQ MVDAIAWAGDFLTGVMGDWPEFPFTHGGVDADAPNRFPAVVSTDGDTKRGRAAVNMHWVLTPDEALVIEF DAHDGFWSLTNMGVFFNSMDFRYRPVSYTASRTAVDTDGKVRLVLAHTDPGFHNWIDTQGFERGNVTYRH MLDGAPVPLRTEVVKHSELAGVLPADTATVTAEERRAQMRVRFDAVGRRYTAL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2496 | - | - | 100% (403) | hypothetical protein Mflv_2496 |
| M. gilvum PYR-GCK | Mflv_4400 | - | e-133 | 56.90% (413) | hypothetical protein Mflv_4400 |
| M. gilvum PYR-GCK | Mflv_1529 | - | 1e-21 | 24.32% (370) | hypothetical protein Mflv_1529 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3561c | - | 2e-20 | 24.84% (318) | hypothetical protein Mb3561c |
| M. tuberculosis H37Rv | Rv3531c | - | 2e-20 | 24.84% (318) | hypothetical protein Rv3531c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4179c | - | 3e-29 | 26.91% (405) | hypothetical protein MAB_4179c |
| M. marinum M | MMAR_0906 | - | 2e-22 | 30.42% (378) | hypothetical protein MMAR_0906 |
| M. avium 104 | MAV_0063 | - | 1e-170 | 68.25% (400) | hypothetical protein MAV_0063 |
| M. smegmatis MC2 155 | MSMEG_5932 | - | 2e-21 | 25.07% (371) | hypothetical protein MSMEG_5932 |
| M. thermoresistible (build 8) | TH_3890 | - | 4e-29 | 29.78% (356) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0659 | - | 2e-22 | 30.42% (378) | hypothetical protein MUL_0659 |
| M. vanbaalenii PYR-1 | Mvan_4829 | - | 5e-24 | 25.82% (395) | hypothetical protein Mvan_4829 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3561c|M.bovis_AF2122/97 ----------------------MYSDPLREAIAEAEQLVAAAPHIET---
Rv3531c|M.tuberculosis_H37Rv ----------------------MYSDPLREAIAEAEQLVAAAPHIET---
MSMEG_5932|M.smegmatis_MC2_155 ----------------------MYSQPLVDAIAEAERLVAAAPFIES---
Mvan_4829|M.vanbaalenii_PYR-1 MRYFIRNIDHSGPILEHMSEVKMYVQEFLDRIAAAERLVREAPHVES---
MAB_4179c|M.abscessus_ATCC_199 ----------------------MYSEAFTAAIVEAEELIVAAPHIET---
MMAR_0906|M.marinum_M -----------MSAETSQASLHAAWTDMIDALTRARDAVDSAELHAPPVT
MUL_0659|M.ulcerans_Agy99 -----------MSAETSQASLHAAWTDMIDALTRARDAVDSAELHAPPVT
Mflv_2496|M.gilvum_PYR-GCK ---------MAYGDGPDDVALRRAWETFCYQVKAAGQQIFKEHNPAS---
MAV_0063|M.avium_104 -------MNMAFGDGPHDAALRAAWTEFCARLQRAGERAFKDHNPAS---
TH_3890|M.thermoresistible__bu -------------------------------MTGTATAVLAPPGNIG---
: :
Mb3561c|M.bovis_AF2122/97 EADLLEGLQYLAGCIAGCMHLAFDY-ERDHPFLQSGTGPFTKMGLDNPDT
Rv3531c|M.tuberculosis_H37Rv EADLLEGLQYLAGCIAGCMHLAFDY-ERDHPFLQSGTGPFTKMGLDNPDT
MSMEG_5932|M.smegmatis_MC2_155 EADLTEGLQYLAGCVSGCLHLAFDY-DRDHPFLQSGTGPFTKMGLDNPDT
Mvan_4829|M.vanbaalenii_PYR-1 EADLLEGLQYLAGCIAACTRLAFDY-DRDHPFLHSGTGPFTKMALDNPDT
MAB_4179c|M.abscessus_ATCC_199 EADLLEGLQYLAQGIAACTHMAFHT-DRDHPFLLSGTGPFTKMGLDNPDT
MMAR_0906|M.marinum_M AAGLADGYGYLLGFVFSGIERAFGE-NPDFPYFRRAIQPLDKATIDNADA
MUL_0659|M.ulcerans_Agy99 AAGLADGYGYLLGFVFSGIERALGE-NPDFPYFRRAIQPLDKATIDNADA
Mflv_2496|M.gilvum_PYR-GCK ELHRVDALRFLTQNLGQAFDLALETRDTRYPGMHAFCGPTRKLGGDCADF
MAV_0063|M.avium_104 GPHRVDAFRFLTQNLGQAFDLALETRDANYPVLHSFCGPTRKLGGDCADF
TH_3890|M.thermoresistible__bu -AATPEGDNIAEMMALAQAQLLQQAADLVRPVWVPFLSKTIRSAGANADT
:. : * : .*
Mb3561c|M.bovis_AF2122/97 LYFGTRLQANRDYVVSGRRGTTTDLSFQLLGG--EYTDYN------VPAS
Rv3531c|M.tuberculosis_H37Rv LYFGTRLQANRDYVVSGRRGTTTDLSFQLLGG--EYTDYN------VPAS
MSMEG_5932|M.smegmatis_MC2_155 LYFGTRVQPGHEYVVTGKRGTTTDLSFQVLGG--EYTDDN------VPAS
Mvan_4829|M.vanbaalenii_PYR-1 LYFGTWLQGGHEYVLTGRRGTTTDLSFQLLGG--EYTEDN------VPDN
MAB_4179c|M.abscessus_ATCC_199 LYFGARVSGEYEYVVTGKRGTTTDLSFQVLGGG-DYTDKN------VPGS
MMAR_0906|M.marinum_M LYLSAPIDGAQSYRVTGRFVGPKPPQYLIFEAHTDYAGDTGGLAELMPGG
MUL_0659|M.ulcerans_Agy99 LYLSAPIDGAQSYRVTGRFVGPKPPQYLIFEAHIDYAGDTGGLAELMPGG
Mflv_2496|M.gilvum_PYR-GCK TYQQAWIDGDSVYRIHGERGTARFFNITVQGPRPDGPGVLH-----EPFG
MAV_0063|M.avium_104 TYQQAWIDGRSTYRITGTRGTSRFFNVTVQGRRTPGEGVLH-----EPFG
TH_3890|M.thermoresistible__bu TYGVALLEPGGSYRISGRRGTVVFADLLVGAGLLGVVERQQPNVG-----
* : :. * : * . :
Mb3561c|M.bovis_AF2122/97 ---QAAFDDRELDIAADGSFEWRLRPS-------------------APGQ
Rv3531c|M.tuberculosis_H37Rv ---QAAFDDRELDIAADGSFEWRLRPS-------------------APGQ
MSMEG_5932|M.smegmatis_MC2_155 ---QAAFDDRELDIAEDGTFEWRITPT-------------------SPSQ
Mvan_4829|M.vanbaalenii_PYR-1 ---QFAFDDRELDLAVDGSFEWRFTPN-------------------SDAQ
MAB_4179c|M.abscessus_ATCC_199 ---AIAFDDREIHIDSDGSFEVRFGPAPADDSR-----PNYFTLGPGPAQ
MMAR_0906|M.marinum_M RVVTGALDTADLAVGEDGRFEILLGPRRPGEHTGNFIATRTPDGTATARF
MUL_0659|M.ulcerans_Agy99 RVVTGALDTADLAVGEDGRFEILLGPRRPGEHTGNFIATRTPDGTATARF
Mflv_2496|M.gilvum_PYR-GCK DVPEASLAGAELAVDHDGTFEVFLGGAPRASN--------WLPTTAGSRK
MAV_0063|M.avium_104 DTPQANLFGQQLRVGADGRFELYVGGPERGHN--------WLPTTPESRK
TH_3890|M.thermoresistible__bu -----VVDFTDLDLGDDDTVELILSAERPAGYDG-----HWFRLDPTADH
. :: : *. .* .
Mb3561c|M.bovis_AF2122/97 LVIREVYGDWSQQRG-TLAIARLDTVGTAPPPLTRELMEKRYATAGSQLV
Rv3531c|M.tuberculosis_H37Rv LVIREVYGDWSQQRG-TLAIARLDTVGTAPPPLTRELMEKRYATAGSQLV
MSMEG_5932|M.smegmatis_MC2_155 LVIREVYNDWSAQRG-HLAIARTDTAGTAPPPLTKELIEKRYAVAGKQLV
Mvan_4829|M.vanbaalenii_PYR-1 LVVREVYNDWSAQRG-TIAIARTDSTGTAPRTLTPELIAIRYAAAGKHLT
MAB_4179c|M.abscessus_ATCC_199 LVMREVYSDWREQRG-SLAIARVDTAGTAPAPLTKEQIEKRYASAGKQLV
MMAR_0906|M.marinum_M LIARILFHDWEHEMSPDLHIVQIGKQGAQPEPADPAVVAQNMRRLGTIVE
MUL_0659|M.ulcerans_Agy99 LIARILFHDWEHEMSPDLHIVQIGKQGAQPEPADPAVVAQNMRRLGTIVE
Mflv_2496|M.gilvum_PYR-GCK LFVRQGFDSWDEIPA-RIAIERVDMAEPKPLPTAQQMVDA-IAWAGDFLT
MAV_0063|M.avium_104 LFIRQGFDSWDEAPA-QLRIERVDMTVPKPLPTPGEMVEA-MRWAGDFVT
TH_3890|M.thermoresistible__bu VWLRQYFYDWETERPWSVTIERLDVAPTDPP-----KPALRDVEINGFVD
: * : .* : * : . . * . :
Mb3561c|M.bovis_AF2122/97 NRVKTWLQFPQWFYLN-----------IPVNTMVAPRLT----PGGLATQ
Rv3531c|M.tuberculosis_H37Rv NRVKTWLQFPQWFYLN-----------IPVNTMVAPRLT----PGGLATQ
MSMEG_5932|M.smegmatis_MC2_155 QRVKTWLQFPQWFYNN-----------LPVNTMVAPRLT----PGGLATQ
Mvan_4829|M.vanbaalenii_PYR-1 RRIRTWLSFPQWFYLN-----------VPVNTLTAPRIT----PGGLATQ
MAB_4179c|M.abscessus_ATCC_199 NRVKTWLQFPKWFYDN-----------LPVNTMTEPRLT----PGGLATQ
MMAR_0906|M.marinum_M NQMRFWNEFYDVVLEAHGDKNGDGFTLMPRNSLNEPALANLAMGGGQSTN
MUL_0659|M.ulcerans_Agy99 NQMRFWNEFYDVVLEAHGDKNGDGFTLMPRNSLNEPALANLAMGGGQSTN
Mflv_2496|M.gilvum_PYR-GCK GVMGDWPEFPFTHGGVDAD---------APNRFPAVVST---DGDTKRGR
MAV_0063|M.avium_104 GLMSDWPEYPFRHGGVDAE---------NPNTFPRAAAT---DADGKRGR
TH_3890|M.thermoresistible__bu RYVSMWQSHVAAMADRG-----------YVNRLETVGLP---DTTGMVAQ
: * .. * : . .
Mb3561c|M.bovis_AF2122/97 YSSAGHFELRPGQALVITVPV-SDAPYLGFQLGSMWYISLDYINHQTSLN
Rv3531c|M.tuberculosis_H37Rv YSSAGHFELRPGQALVITVPV-SDAPYLGFQLGSMWYISLDYINHQTSLN
MSMEG_5932|M.smegmatis_MC2_155 YSSVGHFDLRPDQAMVITLPV-TDAPYLGFQLGSLWYISLDYINHQTSLN
Mvan_4829|M.vanbaalenii_PYR-1 YSSVGHFDLGPGRAMVITLPA-SDAPYLGFQLGSMWYISLDYINHQTSLN
MAB_4179c|M.abscessus_ATCC_199 FSSVGHYDLADDQAMIITVPK-SDAPYQGFQLGSLWYISLDYINHQTSLN
MMAR_0906|M.marinum_M VYCGGVYDLRADEALLVEVVVPVPPAYMGFHLSNLWGESLDYANHACSLN
MUL_0659|M.ulcerans_Agy99 VYCGGVYDLRADEALLVEVVVPVPPAYMGFHLSNLWGESLDYANHACSLN
Mflv_2496|M.gilvum_PYR-GCK AAVNMHWVLTPDEALVIEFDA--HDGFWSLTNMGVFFNSMDFRYRPVSYT
MAV_0063|M.avium_104 AAANMYWELAPDEALIVEFDA--HPGLWMFTNMGVFFNSMDYLYRPVSYT
TH_3890|M.thermoresistible__bu SYFQGVYEIAEDEALLLEVRPPRRCRYWSVQLTDDRYISLDWMWRQTSLN
: : ..*::: . . . *:*: : * .
Mb3561c|M.bovis_AF2122/97 ASQAQADPDGKVRIVVAEQNPGVTNWVETLGHRRGFLQFRWQRVSRELTE
Rv3531c|M.tuberculosis_H37Rv ASQAQADPDGKVRIVVAEQNPGVTNWVETLGHRRGFLQFRWQRVSRELTE
MSMEG_5932|M.smegmatis_MC2_155 GTQAQEDPDGKIRIVVSDANPGVTNWCETLGHRKGYLQFRWQRLSRALTE
Mvan_4829|M.vanbaalenii_PYR-1 GTQAQVDPDGMIRIVVAHESPGIANWVETLGHRRGYLQFRWQRTSRKLTA
MAB_4179c|M.abscessus_ATCC_199 SSQAQIDPDGNIRMVVSNTNPGVTNWIETLGHRRAYLQFRWQRADRQLTP
MMAR_0906|M.marinum_M GFQSEPDADARIRYVIADTDPGVPNWLDTAGRLGGFLTLRWTYCD-PPSE
MUL_0659|M.ulcerans_Agy99 GFQSEPDADARMRYVIADTDPGVPNWLDTAGRLGGFLTLRWTYCD-PPSE
Mflv_2496|M.gilvum_PYR-GCK ASRTAVDTDGKVRLVLAHTDPGFHNWIDTQGFERGNVTYRHMLDG----A
MAV_0063|M.avium_104 PSRTTVDGDGRIRLVMAHRDPGVHNWLDTQGFERGNLTYRHMLEG----E
TH_3890|M.thermoresistible__bu GHQARLDPDGVFRAVISHRDPGVHNWLDAAGWTRGTILGRWNRAD----A
:: * *. .* *::. .**. ** :: * . : * .
Mb3561c|M.bovis_AF2122/97 ADGPTVELVDFDAIPAALPHYQHNKISEDDWRARIALRQRQIATRMLG-
Rv3531c|M.tuberculosis_H37Rv ADGPTVELVDFDAIPAALPHYQHNKISEDDWRARIALRQRQIATRMLG-
MSMEG_5932|M.smegmatis_MC2_155 ADGPTVEVVDIDQVPEKLPYHESNKISEADWRARIALRQQQIQNRMVG-
Mvan_4829|M.vanbaalenii_PYR-1 AEGPIAEVVDFDAIPSRLPYFGHNTISNDDFRTRIALRQNQIANRMVA-
MAB_4179c|M.abscessus_ATCC_199 ADGPTVEVVAVGDIPAKLPHYSQNQISEEGWRSRIAERQTAIGARMLG-
MMAR_0906|M.marinum_M LPKASAVKVPLASVRQHLPADTR-TVSVEERRRQISVRQEHVQRRYRQY
MUL_0659|M.ulcerans_Agy99 LPKASAVKVPLASVRQHLPADTR-TVSVEERRRQISVRQEHVQRRYRQY
Mflv_2496|M.gilvum_PYR-GCK PVPLRTEVVKHSELAGVLP-ADTATVTAEERRAQMRVRFDAVGRRYTAL
MAV_0063|M.avium_104 PAVLDTRVVEHDELLDALP-KDTVMVTPSQRADAMWKRFRGIRRRYVL-
TH_3890|M.thermoresistible__bu NPVPSVKLVDFADLPGFLP-ADVPRITSDERRAQLRARAAAAQRMG---
. * : ** :: : *