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MRYFIRNIDHSGPILEHMSEVKMYVQEFLDRIAAAERLVREAPHVESEADLLEGLQYLAGCIAACTRLAF DYDRDHPFLHSGTGPFTKMALDNPDTLYFGTWLQGGHEYVLTGRRGTTTDLSFQLLGGEYTEDNVPDNQF AFDDRELDLAVDGSFEWRFTPNSDAQLVVREVYNDWSAQRGTIAIARTDSTGTAPRTLTPELIAIRYAAA GKHLTRRIRTWLSFPQWFYLNVPVNTLTAPRITPGGLATQYSSVGHFDLGPGRAMVITLPASDAPYLGFQ LGSMWYISLDYINHQTSLNGTQAQVDPDGMIRIVVAHESPGIANWVETLGHRRGYLQFRWQRTSRKLTAA EGPIAEVVDFDAIPSRLPYFGHNTISNDDFRTRIALRQNQIANRMVA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4829 | - | - | 100% (397) | hypothetical protein Mvan_4829 |
| M. vanbaalenii PYR-1 | Mvan_5229 | - | e-165 | 71.93% (374) | hypothetical protein Mvan_5229 |
| M. vanbaalenii PYR-1 | Mvan_2269 | - | 1e-19 | 23.20% (319) | hypothetical protein Mvan_2269 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3561c | - | 1e-167 | 72.73% (374) | hypothetical protein Mb3561c |
| M. gilvum PYR-GCK | Mflv_1529 | - | 1e-164 | 71.93% (374) | hypothetical protein Mflv_1529 |
| M. tuberculosis H37Rv | Rv3531c | - | 1e-167 | 72.73% (374) | hypothetical protein Rv3531c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4179c | - | 1e-143 | 62.98% (389) | hypothetical protein MAB_4179c |
| M. marinum M | MMAR_5019 | - | 1e-162 | 71.70% (371) | hypothetical protein MMAR_5019 |
| M. avium 104 | MAV_0629 | - | 1e-165 | 72.60% (365) | hypothetical protein MAV_0629 |
| M. smegmatis MC2 155 | MSMEG_5932 | - | 1e-169 | 74.87% (374) | hypothetical protein MSMEG_5932 |
| M. thermoresistible (build 8) | TH_0374 | - | 1e-164 | 71.39% (374) | HYPOTHETICAL PROTEIN Rv3531c |
| M. ulcerans Agy99 | MUL_4093 | - | 1e-162 | 72.60% (365) | hypothetical protein MUL_4093 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3561c|M.bovis_AF2122/97 ----------------------MYSDPLREAIAEAEQLVAAAPHIETEAD
Rv3531c|M.tuberculosis_H37Rv ----------------------MYSDPLREAIAEAEQLVAAAPHIETEAD
MMAR_5019|M.marinum_M --------------------MQPVSQPLTEAIAEAEKLVTAAPHIETEAD
MUL_4093|M.ulcerans_Agy99 --------------------MQPVSQPLTVAIAEAEKLVTAAPHIETEAD
MAV_0629|M.avium_104 ----------------------MFSDPLTSAIAEAENLVAAAPHIETEAD
TH_0374|M.thermoresistible__bu ----------------------MYSQPLLDAIAEAERIVTEAPHIETEAD
Mflv_1529|M.gilvum_PYR-GCK ----------------------MFAQPLADAIAEAEELVSAAPFIESEAD
MSMEG_5932|M.smegmatis_MC2_155 ----------------------MYSQPLVDAIAEAERLVAAAPFIESEAD
Mvan_4829|M.vanbaalenii_PYR-1 MRYFIRNIDHSGPILEHMSEVKMYVQEFLDRIAAAERLVREAPHVESEAD
MAB_4179c|M.abscessus_ATCC_199 ----------------------MYSEAFTAAIVEAEELIVAAPHIETEAD
: : *. **.:: **.:*:***
Mb3561c|M.bovis_AF2122/97 LLEGLQYLAGCIAGCMHLAFDYERDHPFLQSGTGPFTKMGLDNPDTLYFG
Rv3531c|M.tuberculosis_H37Rv LLEGLQYLAGCIAGCMHLAFDYERDHPFLQSGTGPFTKMGLDNPDTLYFG
MMAR_5019|M.marinum_M LLEGLQYLAGCIAGCLHLAFDYERDHPFLQSGTGPFTKMGLDNPDTLYFG
MUL_4093|M.ulcerans_Agy99 LLEGLQYLAGCIAGCLHLAFDYERDHPFLQSGTGPFTKMGLDNPDTLYFG
MAV_0629|M.avium_104 LLEGLQYLAGCISACIHLAVDYERDHPFLQSGTGPFTKMGLDNPDTLYFG
TH_0374|M.thermoresistible__bu LLEGLHYLAGCISACIHLAFDYERDHPFLQSGTGPFTKMGLDNPDTLYFG
Mflv_1529|M.gilvum_PYR-GCK LLEGLQYLAGCIAACTHVAFDYDRDHPFLHSGTGPFTKMGLDNPDTMYFG
MSMEG_5932|M.smegmatis_MC2_155 LTEGLQYLAGCVSGCLHLAFDYDRDHPFLQSGTGPFTKMGLDNPDTLYFG
Mvan_4829|M.vanbaalenii_PYR-1 LLEGLQYLAGCIAACTRLAFDYDRDHPFLHSGTGPFTKMALDNPDTLYFG
MAB_4179c|M.abscessus_ATCC_199 LLEGLQYLAQGIAACTHMAFHTDRDHPFLLSGTGPFTKMGLDNPDTLYFG
* ***:*** ::.* ::*.. :****** *********.******:***
Mb3561c|M.bovis_AF2122/97 TRLQANRDYVVSGRRGTTTDLSFQLLGG-EYTDYNVPASQAAFDDRELDI
Rv3531c|M.tuberculosis_H37Rv TRLQANRDYVVSGRRGTTTDLSFQLLGG-EYTDYNVPASQAAFDDRELDI
MMAR_5019|M.marinum_M TRVHADRDYVVIGNRGTTTDLSFQLLGG-EYTDNNVPVSQAAFDDRELEI
MUL_4093|M.ulcerans_Agy99 TRVHADRDYVVIGNRGTTTDLSFQLLGG-EYTDDNVPVSQAAFDDRELEI
MAV_0629|M.avium_104 TRVHAGYDYVVTGRRGTTTDLSFQLLGG-EYTDDNVPASQAAFDDRELDI
TH_0374|M.thermoresistible__bu TRVLPGHEYVVTGTRGTTTDLSFQLLGG-EYTDEGVPESQAAFDDRELDI
Mflv_1529|M.gilvum_PYR-GCK TRVQPGHEYVVTGRRGTTTDVSFQLLGG-EYTDEVVPDSDTAFDDRKLDI
MSMEG_5932|M.smegmatis_MC2_155 TRVQPGHEYVVTGKRGTTTDLSFQVLGG-EYTDDNVPASQAAFDDRELDI
Mvan_4829|M.vanbaalenii_PYR-1 TWLQGGHEYVLTGRRGTTTDLSFQLLGG-EYTEDNVPDNQFAFDDRELDL
MAB_4179c|M.abscessus_ATCC_199 ARVSGEYEYVVTGKRGTTTDLSFQVLGGGDYTDKNVPGSAIAFDDREIHI
: : :**: * ******:***:*** :**: ** . *****::.:
Mb3561c|M.bovis_AF2122/97 AADGSFEWRLRPS--------------APGQLVIREVYGDWSQQRGTLAI
Rv3531c|M.tuberculosis_H37Rv AADGSFEWRLRPS--------------APGQLVIREVYGDWSQQRGTLAI
MMAR_5019|M.marinum_M ASDGSFQWRLRPT--------------SNGQLVIREVYADWSAQRGTLAI
MUL_4093|M.ulcerans_Agy99 ASDGSFQWRLRPT--------------SNGQLVIREVYADWSAQRGTLAI
MAV_0629|M.avium_104 APDGSFEWRVRPT--------------SNGQLVIREVYGDWAAQRGTLAI
TH_0374|M.thermoresistible__bu GEDGRFEWRFTPE--------------QPSQLVIREVYGDWSQQRGTIAI
Mflv_1529|M.gilvum_PYR-GCK AADGTFEWRFTPA--------------VPSQLVIREVYNDWSAQRGTFAI
MSMEG_5932|M.smegmatis_MC2_155 AEDGTFEWRITPT--------------SPSQLVIREVYNDWSAQRGHLAI
Mvan_4829|M.vanbaalenii_PYR-1 AVDGSFEWRFTPN--------------SDAQLVVREVYNDWSAQRGTIAI
MAB_4179c|M.abscessus_ATCC_199 DSDGSFEVRFGPAPADDSRPNYFTLGPGPAQLVMREVYSDWREQRGSLAI
** *: *. * .***:**** ** *** :**
Mb3561c|M.bovis_AF2122/97 ARLDTVGTAPPPLTRELMEKRYATAGSQLVNRVKTWLQFPQWFYLNIPVN
Rv3531c|M.tuberculosis_H37Rv ARLDTVGTAPPPLTRELMEKRYATAGSQLVNRVKTWLQFPQWFYLNIPVN
MMAR_5019|M.marinum_M SRLDTAGTAPPPLTRETMQKRYTVAGKQLVDRVKTWLQFPQWFYLNIPVN
MUL_4093|M.ulcerans_Agy99 SRLDTAGTAPPPLTRETMQKRYTVAGKQLVDRVKTWLQFPQWFYLNIPVN
MAV_0629|M.avium_104 AREDTAGTAPPPLTRETIEKRYATAGKQLVNRVKTWLQFPQWFYFNIPVN
TH_0374|M.thermoresistible__bu ARTDTAGTAPPPPTRRTIEKRYAVAGRQLVQRVKTWLQFPQWFYFNIPVN
Mflv_1529|M.gilvum_PYR-GCK ARTDTAGTAPPPLTRELIEKRYTVAGKQLVQRVKTWLQFPQWFYNDSPPN
MSMEG_5932|M.smegmatis_MC2_155 ARTDTAGTAPPPLTKELIEKRYAVAGKQLVQRVKTWLQFPQWFYNNLPVN
Mvan_4829|M.vanbaalenii_PYR-1 ARTDSTGTAPRTLTPELIAIRYAAAGKHLTRRIRTWLSFPQWFYLNVPVN
MAB_4179c|M.abscessus_ATCC_199 ARVDTAGTAPAPLTKEQIEKRYASAGKQLVNRVKTWLQFPKWFYDNLPVN
:* *:.**** . * . : **: ** :*. *::***.**:*** : * *
Mb3561c|M.bovis_AF2122/97 TMVAPRLTPGGLATQYSSAGHFELRPGQALVITVPVSDAPYLGFQLGSMW
Rv3531c|M.tuberculosis_H37Rv TMVAPRLTPGGLATQYSSAGHFELRPGQALVITVPVSDAPYLGFQLGSMW
MMAR_5019|M.marinum_M TMVAPRLTPGGLATQYSSAGHFDLRPDQALVITVPVSDAPYLGFQLGSMW
MUL_4093|M.ulcerans_Agy99 TMVVPRLTPGGLATQYSSAGHFDLRPDQALVITVPVSDAPYLGFQLGSMW
MAV_0629|M.avium_104 TMVAPRLTPGGLATQYSSAGHYELRPDQALLITIPVTDAPYLGFQLGSLW
TH_0374|M.thermoresistible__bu TMVPPRLTPGGLSTQYSSAGHYELEPDQAMIITVPVSDAPYLGFQLGSLW
Mflv_1529|M.gilvum_PYR-GCK TMVAPRLTPGGLATQYSSAGQFDLAEDQALIITLPVTDAPYLGFQLGSLW
MSMEG_5932|M.smegmatis_MC2_155 TMVAPRLTPGGLATQYSSVGHFDLRPDQAMVITLPVTDAPYLGFQLGSLW
Mvan_4829|M.vanbaalenii_PYR-1 TLTAPRITPGGLATQYSSVGHFDLGPGRAMVITLPASDAPYLGFQLGSMW
MAB_4179c|M.abscessus_ATCC_199 TMTEPRLTPGGLATQFSSVGHYDLADDQAMIITVPKSDAPYQGFQLGSLW
*:. **:*****:**:**.*:::* .:*::**:* :**** ******:*
Mb3561c|M.bovis_AF2122/97 YISLDYINHQTSLNASQAQADPDGKVRIVVAEQNPGVTNWVETLGHRRGF
Rv3531c|M.tuberculosis_H37Rv YISLDYINHQTSLNASQAQADPDGKVRIVVAEQNPGVTNWVETLGHRRGF
MMAR_5019|M.marinum_M YISLDYINHQTSLNNSQAQADPDGKVRIVVADRNPGVTNWVETLGHRRGF
MUL_4093|M.ulcerans_Agy99 YISLDYINHQTSLNNSQAQADPDGKVRIVVADRNPGVTNWVETLGHRRGF
MAV_0629|M.avium_104 YISLDYINHQTSLNNTQAQADPDGKVRIVVAEQNPGVTNWVETVGHRKGF
TH_0374|M.thermoresistible__bu YISLDYINHQTSLNATQAQADPDGRIRIVVSEANPGVTNWVETLGHRRGI
Mflv_1529|M.gilvum_PYR-GCK YISLDYINHQTSLNGTQAQADPDDKIRIVVSDRNPGVTNWVETLGHRKGF
MSMEG_5932|M.smegmatis_MC2_155 YISLDYINHQTSLNGTQAQEDPDGKIRIVVSDANPGVTNWCETLGHRKGY
Mvan_4829|M.vanbaalenii_PYR-1 YISLDYINHQTSLNGTQAQVDPDGMIRIVVAHESPGIANWVETLGHRRGY
MAB_4179c|M.abscessus_ATCC_199 YISLDYINHQTSLNSSQAQIDPDGNIRMVVSNTNPGVTNWIETLGHRRAY
************** :*** ***. :*:**:. .**::** **:***:.
Mb3561c|M.bovis_AF2122/97 LQFRWQRVSRELTEADGPTVELVDFDAIPAALPHYQHNKISEDDWRARIA
Rv3531c|M.tuberculosis_H37Rv LQFRWQRVSRELTEADGPTVELVDFDAIPAALPHYQHNKISEDDWRARIA
MMAR_5019|M.marinum_M LQFRWQRVSRQLTDADGPSVELVDFDAVGSVLPYLEHNKISEEDWRARIA
MUL_4093|M.ulcerans_Agy99 LQFRWQRVSRQLTDADGPSVELVDFDAVGSVLPYLEHNKISEEDWRARIA
MAV_0629|M.avium_104 LQFRWQRVSRQLTEADGPTVELVDFDAVPAKLPYYEHNKISDDEWRARIA
TH_0374|M.thermoresistible__bu MQFRWQRVSRPLTEADGPTVEVVDFDQVPAALPYYESNRISEEAWRARIA
Mflv_1529|M.gilvum_PYR-GCK LQFRWQRVSREMTAADGPTVELVHVDDVASALPYHDSNTISEEDWRARIA
MSMEG_5932|M.smegmatis_MC2_155 LQFRWQRLSRALTEADGPTVEVVDIDQVPEKLPYHESNKISEADWRARIA
Mvan_4829|M.vanbaalenii_PYR-1 LQFRWQRTSRKLTAAEGPIAEVVDFDAIPSRLPYFGHNTISNDDFRTRIA
MAB_4179c|M.abscessus_ATCC_199 LQFRWQRADRQLTPADGPTVEVVAVGDIPAKLPHYSQNQISEEGWRSRIA
:****** .* :* *:** .*:* .. : **: * **: :*:***
Mb3561c|M.bovis_AF2122/97 LRQRQIATRMLG
Rv3531c|M.tuberculosis_H37Rv LRQRQIATRMLG
MMAR_5019|M.marinum_M LRQKQIAARMLG
MUL_4093|M.ulcerans_Agy99 LRQKQIAARMLG
MAV_0629|M.avium_104 LRQQQIAARMLG
TH_0374|M.thermoresistible__bu QRQIQIANRMLG
Mflv_1529|M.gilvum_PYR-GCK LRQKQIGERMVG
MSMEG_5932|M.smegmatis_MC2_155 LRQQQIQNRMVG
Mvan_4829|M.vanbaalenii_PYR-1 LRQNQIANRMVA
MAB_4179c|M.abscessus_ATCC_199 ERQTAIGARMLG
** * **:.