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TTESHEATAAWRELLDTLRTLDASFMSGPKAVGDDRHVADGYRMLATTLGVAFDTYLFADPSRPHWVELN SPFRPDRRWGGDNTDAIYFMCPVDPHRRYRISGNRGDSVYFSMTAYNEPAPGAWSDKIVAIVRDDDLDID AEGNFSFEFGPQPGAAVLMTRDYQADPLVGRAATWTIEALEPPDPFRHGEAETAAALRASAAWMRTMFAI LPLSVGVKNADAHELGHETALVANDFADPYQVPDANFGWSARDACYSYGSFDLAEDEALVITHRPPACRF WNLVVWNQFMAVPGVEDARSSVNGYTAAPNGDGSVTVVLSRGMTAHPNSLTTLDYPRGNLAFRWFLADEV PARPEVRLVKVSDAPTAVT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4383 | - | - | 100% (370) | hypothetical protein Mflv_4383 |
| M. gilvum PYR-GCK | Mflv_4114 | - | 5e-90 | 43.86% (383) | hypothetical protein Mflv_4114 |
| M. gilvum PYR-GCK | Mflv_4073 | - | 2e-19 | 27.48% (353) | hypothetical protein Mflv_4073 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3561c | - | 3e-09 | 23.99% (321) | hypothetical protein Mb3561c |
| M. tuberculosis H37Rv | Rv3531c | - | 3e-09 | 23.99% (321) | hypothetical protein Rv3531c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4179c | - | 6e-13 | 26.22% (347) | hypothetical protein MAB_4179c |
| M. marinum M | MMAR_0339 | - | 1e-171 | 76.63% (368) | hypothetical protein MMAR_0339 |
| M. avium 104 | MAV_5166 | - | 1e-167 | 75.27% (368) | hypothetical protein MAV_5166 |
| M. smegmatis MC2 155 | MSMEG_5932 | - | 5e-09 | 24.76% (307) | hypothetical protein MSMEG_5932 |
| M. thermoresistible (build 8) | TH_3890 | - | 2e-14 | 26.61% (327) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4781 | - | 1e-169 | 76.09% (368) | hypothetical protein MUL_4781 |
| M. vanbaalenii PYR-1 | Mvan_1962 | - | 0.0 | 86.22% (370) | hypothetical protein Mvan_1962 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4383|M.gilvum_PYR-GCK MTTESHEATAAWRELLDTLRTLDASFMSGPKAVGDDRHVADGYRMLATTL
Mvan_1962|M.vanbaalenii_PYR-1 MTTESHEATAAWRELLDTLRGLDESFMTGPKSVTDDRHIADGYRMIATTL
MMAR_0339|M.marinum_M ---MTYESTTAWQELLDTLRTLDSSFLEGERAVTDDRHVADGYRMLATTL
MUL_4781|M.ulcerans_Agy99 ---MTYESTAAWQELLDTLRTLDSSFLEGERAVTDDRHVADGYRMLATTL
MAV_5166|M.avium_104 ---MTHESTTAWRELLAALGELDRSFLEGDRAVSDDRHIADGYRMLATTL
Mb3561c|M.bovis_AF2122/97 ----------MYSDPLREAIAEAEQLVAAAPHIETEADLLEGLQYLAGCI
Rv3531c|M.tuberculosis_H37Rv ----------MYSDPLREAIAEAEQLVAAAPHIETEADLLEGLQYLAGCI
MSMEG_5932|M.smegmatis_MC2_155 ----------MYSQPLVDAIAEAERLVAAAPFIESEADLTEGLQYLAGCV
MAB_4179c|M.abscessus_ATCC_199 ----------MYSEAFTAAIVEAEELIVAAPHIETEADLLEGLQYLAQGI
TH_3890|M.thermoresistible__bu ------------------MTGTATAVLAPPGNIGAATPEGDNIAEMMA-L
.: : :. : :
Mflv_4383|M.gilvum_PYR-GCK GVAFDTYLFADPSRPHWVELNSPFRPDRRWGGDNTDAIYFMCPVDPHRRY
Mvan_1962|M.vanbaalenii_PYR-1 GVALDTYLFADRSRPRWLEVNSPFRPDRRWGGDNTDAIYYMCPVDPARRY
MMAR_0339|M.marinum_M GVAFDAYLFPEPGRPQFVAVNTPFRRDRRWGGDNTDAYYFMCPVDPDRRY
MUL_4781|M.ulcerans_Agy99 GVAFNAYLFPEPGRPQFVAVNTPFRRDRRWGGDNTDAYYFMCPVDPDRRY
MAV_5166|M.avium_104 GVAFDTYLFPEPDRPQFVAVNTPFRRDRRWGGDNTDAYYFICPVDPKRRY
Mb3561c|M.bovis_AF2122/97 AGCMHLAFDYERDHPFLQSGTGPFT---KMGLDNPDTLYFGTRLQANRDY
Rv3531c|M.tuberculosis_H37Rv AGCMHLAFDYERDHPFLQSGTGPFT---KMGLDNPDTLYFGTRLQANRDY
MSMEG_5932|M.smegmatis_MC2_155 SGCLHLAFDYDRDHPFLQSGTGPFT---KMGLDNPDTLYFGTRVQPGHEY
MAB_4179c|M.abscessus_ATCC_199 AACTHMAFHTDRDHPFLLSGTGPFT---KMGLDNPDTLYFGARVSGEYEY
TH_3890|M.thermoresistible__bu AQAQLLQQAADLVRPVWVPFLSKTI---RSAGANADTTYGVALLEPGGSY
. . : :* : . *.*: * :. *
Mflv_4383|M.gilvum_PYR-GCK RISGNRGDSVYFSMTAYNE-PAPGAWSDKIVAIVRDDDLDIDAEGNFSFE
Mvan_1962|M.vanbaalenii_PYR-1 RISGNRGDSVYFSVTAYNE-PSPGAWSDRIVAILRDDDLDFDEDGNFSFD
MMAR_0339|M.marinum_M RISGNKGDSVYFSVTAYNE-PAPGAWSDRIVAIVRDSDLDVDADGNFSFE
MUL_4781|M.ulcerans_Agy99 RISGNKGDSVYFSVTAYNE-PAPGAWSDRIVAIVRDSDLDVDADGNFSFE
MAV_5166|M.avium_104 RISGNKGDSVYFSVTAYNE-PSLGAWSDRVVAIVRDSDLDVDADGNFSFE
Mb3561c|M.bovis_AF2122/97 VVSGRRGTTTDLSFQLLGG-EYTDYNVPASQAAFDDRELDIAADGSFEWR
Rv3531c|M.tuberculosis_H37Rv VVSGRRGTTTDLSFQLLGG-EYTDYNVPASQAAFDDRELDIAADGSFEWR
MSMEG_5932|M.smegmatis_MC2_155 VVTGKRGTTTDLSFQVLGG-EYTDDNVPASQAAFDDRELDIAEDGTFEWR
MAB_4179c|M.abscessus_ATCC_199 VVTGKRGTTTDLSFQVLGGGDYTDKNVPGSAIAFDDREIHIDSDGSFEVR
TH_3890|M.thermoresistible__bu RISGRRGTVVFADLLVGAGLLGVVERQQPNVGVVDFTDLDLGDDDTVELI
::*.:* . .. . ::.. :....
Mflv_4383|M.gilvum_PYR-GCK FGPQP---GAAVLMTRDYQADPLVGRAATWTIEALEPPDPFRHGEAETAA
Mvan_1962|M.vanbaalenii_PYR-1 FGPEP---DAAVLMTRDYQADPSVGRPVTWTIEALEPPDPFRHGEAETAA
MMAR_0339|M.marinum_M LGPTP---DAAVLMTRDYQANPLTGRPITWHIEALDEPDPIRHADPQTAA
MUL_4781|M.ulcerans_Agy99 LGPTP---DAAVLMTRDYQANPLTGRPITWHIEALDEPDPIRHADPQTAA
MAV_5166|M.avium_104 FPPTP---DAAVLMTRDYQADPLTGRPVTWRIEALDEPAPIRHGDAETAA
Mb3561c|M.bovis_AF2122/97 LRPS--------------APGQLVIREVYGDWSQQRGTLAIARLDTVGTA
Rv3531c|M.tuberculosis_H37Rv LRPS--------------APGQLVIREVYGDWSQQRGTLAIARLDTVGTA
MSMEG_5932|M.smegmatis_MC2_155 ITPT--------------SPSQLVIREVYNDWSAQRGHLAIARTDTAGTA
MAB_4179c|M.abscessus_ATCC_199 FGPAPADDSRPNYFTLGPGPAQLVMREVYSDWREQRGSLAIARVDTAGTA
TH_3890|M.thermoresistible__bu LSAERPAGYDGHWFRLDPTADHVWLRQYFYDWETERPWSVTIERLDVAPT
: . . * . .:
Mflv_4383|M.gilvum_PYR-GCK ALRASAAWMRTMFAILPLSVGVKN---ADAHELGHETALVANDFADPYQV
Mvan_1962|M.vanbaalenii_PYR-1 ALRAGAAWLRTMFAILPLAVGVKN---ADVHRLGHETAMAANEFADPYQV
MMAR_0339|M.marinum_M GLRSVATWLRTMFAIMPLPVGTRDQDLPDEHALGHNTAHAANQFADPYQV
MUL_4781|M.ulcerans_Agy99 GLRSVATWLRTMFAIMPLPVGTRDQDLPDEHALGHNTAHAANQFADPYQV
MAV_5166|M.avium_104 RLRAVATWLRTMFAIVPLAVGNR---VDDQHALGHETAHAANAFADPYQV
Mb3561c|M.bovis_AF2122/97 PPPLTRELMEKRYATAGSQLVNRVKTWLQFPQWFYLN-IPVNTMVAPRLT
Rv3531c|M.tuberculosis_H37Rv PPPLTRELMEKRYATAGSQLVNRVKTWLQFPQWFYLN-IPVNTMVAPRLT
MSMEG_5932|M.smegmatis_MC2_155 PPPLTKELIEKRYAVAGKQLVQRVKTWLQFPQWFYNN-LPVNTMVAPRLT
MAB_4179c|M.abscessus_ATCC_199 PAPLTKEQIEKRYASAGKQLVNRVKTWLQFPKWFYDN-LPVNTMTEPRLT
TH_3890|M.thermoresistible__bu DPPKPALRDVEINGFVDRYVSMWQSHVAAMADRGYVNRLETVGLPDTTG-
. : : . . : .
Mflv_4383|M.gilvum_PYR-GCK PDANFGWSARDACYSYGSFDLAEDEALVITHRPPA-CRFWNLVVWNQFMA
Mvan_1962|M.vanbaalenii_PYR-1 PDANFGWSARDACYAYGSFDLAEDEALVITHRPPG-CRFWNLVVWNQFMA
MMAR_0339|M.marinum_M PDANFGWSARDACYCYGSFVLDDDEALVITHRPPS-CRFWNLVVWNQFMA
MUL_4781|M.ulcerans_Agy99 PDANFGWSARDACYCYGSFVLDD-EALVITHRLPS-CRFWNLVVWNQFMA
MAV_5166|M.avium_104 PDANFGWSARDACYSYGSFVLDDDEALVITHRPPS-CRFWNMVVWNQFMA
Mb3561c|M.bovis_AF2122/97 PGG-----LATQYSSAGHFELRPGQALVITVPVSD-APYLGFQLGSMWYI
Rv3531c|M.tuberculosis_H37Rv PGG-----LATQYSSAGHFELRPGQALVITVPVSD-APYLGFQLGSMWYI
MSMEG_5932|M.smegmatis_MC2_155 PGG-----LATQYSSVGHFDLRPDQAMVITLPVTD-APYLGFQLGSLWYI
MAB_4179c|M.abscessus_ATCC_199 PGG-----LATQFSSVGHYDLADDQAMIITVPKSD-APYQGFQLGSLWYI
TH_3890|M.thermoresistible__bu --------MVAQSYFQGVYEIAEDEALLLEVRPPRRCRYWSVQLTDDRYI
* : : :*::: . . : .. : .
Mflv_4383|M.gilvum_PYR-GCK VPGVE---DARSSVNGYTAAPNGDGSVTVVLSRGMTAHPNSLTTLDYPRG
Mvan_1962|M.vanbaalenii_PYR-1 VPGVS---DARSSVNGSTAVPNSDGSVTVVVSRGMTSHPNSLTTLDYPRG
MMAR_0339|M.marinum_M TCGAA---DARCSVNGHSAIANSDGSVTVVLSRGVTTHPNSLTTLDYPRG
MUL_4781|M.ulcerans_Agy99 TCGAA---DARCSVNGHSAIANSDGSVTVVLSRGVTTHPNSLATLDYPRG
MAV_5166|M.avium_104 TYGAAEGPDARCSINGHSAVANSDGTVTIVLSRDRTPHPNSVTTLGYPRG
Mb3561c|M.bovis_AF2122/97 SLDYIN---HQTSLNASQAQADPDGKVRIVVAEQNPGVTNWVETLGHRRG
Rv3531c|M.tuberculosis_H37Rv SLDYIN---HQTSLNASQAQADPDGKVRIVVAEQNPGVTNWVETLGHRRG
MSMEG_5932|M.smegmatis_MC2_155 SLDYIN---HQTSLNGTQAQEDPDGKIRIVVSDANPGVTNWCETLGHRKG
MAB_4179c|M.abscessus_ATCC_199 SLDYIN---HQTSLNSSQAQIDPDGNIRMVVSNTNPGVTNWIETLGHRRA
TH_3890|M.thermoresistible__bu SLDWMWR---QTSLNGHQARLDPDGVFRAVISHRDPGVHNWLDAAGWTRG
. : *:*. * : ** . *:: . * : . :.
Mflv_4383|M.gilvum_PYR-GCK NLAFRWFLAD---EVPARPEVRLVKVSDAPTAVT----------------
Mvan_1962|M.vanbaalenii_PYR-1 NLAFRWFLAD---QVPARPEVMLVDVAEAPTTVS----------------
MMAR_0339|M.marinum_M NLAFRWFLAD---GVPARPEVKLVKLADAPTEVA----------------
MUL_4781|M.ulcerans_Agy99 NLAFRWFLAD---GVPARPEVKLVKLADAPTEVA----------------
MAV_5166|M.avium_104 NLAFRWFLAD---GVPARPEVELVKASDAPTAVR----------------
Mb3561c|M.bovis_AF2122/97 FLQFRWQRVSRELTEADGPTVELVDFDAIPAALPHYQHNKISEDDWRARI
Rv3531c|M.tuberculosis_H37Rv FLQFRWQRVSRELTEADGPTVELVDFDAIPAALPHYQHNKISEDDWRARI
MSMEG_5932|M.smegmatis_MC2_155 YLQFRWQRLSRALTEADGPTVEVVDIDQVPEKLPYHESNKISEADWRARI
MAB_4179c|M.abscessus_ATCC_199 YLQFRWQRADRQLTPADGPTVEVVAVGDIPAKLPHYSQNQISEEGWRSRI
TH_3890|M.thermoresistible__bu TILGRWNRAD----ANPVPSVKLVDFADLPGFLPADVPRITSDER---RA
: ** . * * :* * :
Mflv_4383|M.gilvum_PYR-GCK -------------
Mvan_1962|M.vanbaalenii_PYR-1 -------------
MMAR_0339|M.marinum_M -------------
MUL_4781|M.ulcerans_Agy99 -------------
MAV_5166|M.avium_104 -------------
Mb3561c|M.bovis_AF2122/97 ALRQRQIATRMLG
Rv3531c|M.tuberculosis_H37Rv ALRQRQIATRMLG
MSMEG_5932|M.smegmatis_MC2_155 ALRQQQIQNRMVG
MAB_4179c|M.abscessus_ATCC_199 AERQTAIGARMLG
TH_3890|M.thermoresistible__bu QLRARAAAAQRMG