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SSTESAAAWRELLSAFAEFDNQFLDGPKAVRGQTAVAEGYQNLATMLALSLDMHFFADPVAPRFLDTLTP FRPDRRWGGDNTDCYYGYAVVDPRRTYRVSGTPNDSVMYSITVYNEPEPGAWPNRTVGLLYDTDMPIGED GRFSCVLGPRRPDGYGGPFIELAPDARGIITRDYHEHPESGARVEWDIEVVDHAGLEVVPAKSDADVARS LRATLRFAQDMYALIPLILAERKPVELADGQSLSLNTLAPPYRAGAATHGFSMQDACYSLGGFSLEPGEA LVITSTHPRCRFWNLTLWNQYMAALDVEYGRAGINSGSAVPNSDGSVTIVVSTEQLAHPNALSTKGHPEG LMSFRWFLSDDLPERPVAEVVPVAQAPVSVS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4114 | - | - | 100% (382) | hypothetical protein Mflv_4114 |
| M. gilvum PYR-GCK | Mflv_4383 | - | 5e-90 | 43.86% (383) | hypothetical protein Mflv_4383 |
| M. gilvum PYR-GCK | Mflv_4073 | - | 6e-22 | 25.87% (344) | hypothetical protein Mflv_4073 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3561c | - | 6e-12 | 24.36% (390) | hypothetical protein Mb3561c |
| M. tuberculosis H37Rv | Rv3531c | - | 6e-12 | 24.36% (390) | hypothetical protein Rv3531c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3969 | - | 1e-16 | 24.15% (381) | hypothetical protein MAB_3969 |
| M. marinum M | MMAR_0339 | - | 4e-89 | 43.64% (385) | hypothetical protein MMAR_0339 |
| M. avium 104 | MAV_5166 | - | 3e-91 | 44.65% (383) | hypothetical protein MAV_5166 |
| M. smegmatis MC2 155 | MSMEG_5932 | - | 1e-13 | 25.94% (374) | hypothetical protein MSMEG_5932 |
| M. thermoresistible (build 8) | TH_3890 | - | 2e-16 | 26.27% (354) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4781 | - | 8e-88 | 43.64% (385) | hypothetical protein MUL_4781 |
| M. vanbaalenii PYR-1 | Mvan_2231 | - | 0.0 | 89.50% (381) | hypothetical protein Mvan_2231 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3561c|M.bovis_AF2122/97 ----------MYSDPLREAIAEAEQLVAAAPHIETEADLLEGLQYLAGCI
Rv3531c|M.tuberculosis_H37Rv ----------MYSDPLREAIAEAEQLVAAAPHIETEADLLEGLQYLAGCI
MSMEG_5932|M.smegmatis_MC2_155 ----------MYSQPLVDAIAEAERLVAAAPFIESEADLTEGLQYLAGCV
MAB_3969|M.abscessus_ATCC_1997 -----MATDDAVTQPFTDAIAEAEKLVASAPHIESEADLLEGLEYLAGSI
Mflv_4114|M.gilvum_PYR-GCK MSS--TESAAAWRELLSAFAEFDNQFLDGPKAVRGQTAVAEGYQNLATML
Mvan_2231|M.vanbaalenii_PYR-1 MSSSAGESAAAWRELLSAFADFDTQFLDGPKAVRGQTAVAEGYQNLATML
MMAR_0339|M.marinum_M MTY---ESTTAWQELLDTLRTLDSSFLEGERAVTDDRHVADGYRMLATTL
MUL_4781|M.ulcerans_Agy99 MTY---ESTAAWQELLDTLRTLDSSFLEGERAVTDDRHVADGYRMLATTL
MAV_5166|M.avium_104 MTH---ESTTAWRELLAALGELDRSFLEGDRAVSDDRHIADGYRMLATTL
TH_3890|M.thermoresistible__bu ------------------MTGTATAVLAPPGNIGAATPEGDNIAEMM-AL
.: : :. : :
Mb3561c|M.bovis_AF2122/97 AGCMHLAFDYERDHPFLQSGTGPFT---KMGLDNPDTLYFGTRLQANRDY
Rv3531c|M.tuberculosis_H37Rv AGCMHLAFDYERDHPFLQSGTGPFT---KMGLDNPDTLYFGTRLQANRDY
MSMEG_5932|M.smegmatis_MC2_155 SGCLHLAFDYDRDHPFLQSGTGPFT---KMGLDNPDTLYFGTRVQPGHEY
MAB_3969|M.abscessus_ATCC_1997 AASLHLVYNFSTEHPVLLSGTGPFT---KMGLDNPDFLYFATQIDGHHDY
Mflv_4114|M.gilvum_PYR-GCK ALSLDMHFFADPVAPRFLDTLTPFRPDRRWGGDNTDCYYGYAVVDPRRTY
Mvan_2231|M.vanbaalenii_PYR-1 ALSLDMHYFADPVAPRFIDTLTPFRPDRRWGGDNTDCYYGYAAVDPRRTY
MMAR_0339|M.marinum_M GVAFDAYLFPEPGRPQFVAVNTPFRRDRRWGGDNTDAYYFMCPVDPDRRY
MUL_4781|M.ulcerans_Agy99 GVAFNAYLFPEPGRPQFVAVNTPFRRDRRWGGDNTDAYYFMCPVDPDRRY
MAV_5166|M.avium_104 GVAFDTYLFPEPDRPQFVAVNTPFRRDRRWGGDNTDAYYFICPVDPKRRY
TH_3890|M.thermoresistible__bu AQAQLLQQAADLVRPVWVPFLSKTI---RSAGANADTTYGVALLEPGGSY
. . . * : . *.* * :: *
Mb3561c|M.bovis_AF2122/97 VVSGRRGTTTDLSFQLLGGEY-TDYNVPASQAAFDDRELDIAADGSFEWR
Rv3531c|M.tuberculosis_H37Rv VVSGRRGTTTDLSFQLLGGEY-TDYNVPASQAAFDDRELDIAADGSFEWR
MSMEG_5932|M.smegmatis_MC2_155 VVTGKRGTTTDLSFQVLGGEY-TDDNVPASQAAFDDRELDIAEDGTFEWR
MAB_3969|M.abscessus_ATCC_1997 VLSGTRGSTVDLNFQLLDSAY-TDRDVPESVTAFDDRNLAIHEDGSYRVS
Mflv_4114|M.gilvum_PYR-GCK RVSGTPNDSVMYSITVYNEPE-PGAWPNRTVGLLYDTDMPIGEDGRFSCV
Mvan_2231|M.vanbaalenii_PYR-1 RISGRPNDSVMYSVTVYNEPE-PGAWPNRTVGLLYDVDMPIDVDGRFRCV
MMAR_0339|M.marinum_M RISGNKGDSVYFSVTAYNEPA-PGAWSDRIVAIVRDSDLDVDADGNFSFE
MUL_4781|M.ulcerans_Agy99 RISGNKGDSVYFSVTAYNEPA-PGAWSDRIVAIVRDSDLDVDADGNFSFE
MAV_5166|M.avium_104 RISGNKGDSVYFSVTAYNEPS-LGAWSDRVVAIVRDSDLDVDADGNFSFE
TH_3890|M.thermoresistible__bu RISGRRGTVVFADLLVGAGLLGVVERQQPNVGVVDFTDLDLGDDDTVELI
::* . . .. . :: : *.
Mb3561c|M.bovis_AF2122/97 LRPS-------------APGQLVIREVYGDWSQQRG--------------
Rv3531c|M.tuberculosis_H37Rv LRPS-------------APGQLVIREVYGDWSQQRG--------------
MSMEG_5932|M.smegmatis_MC2_155 ITPT-------------SPSQLVIREVYNDWSAQRG--------------
MAB_3969|M.abscessus_ATCC_1997 IGAAPVTGCDTHIPIAPRPAQLIVREAYNDWTENRG--------------
Mflv_4114|M.gilvum_PYR-GCK LGPRRPDGYGGPFIELAPDARGIITRDYHEHPESGARVEWDIEVVDHAGL
Mvan_2231|M.vanbaalenii_PYR-1 LGPQRPAGYDGPFIELSHDARGIITRDYHEHPESGARVQWDIEVVDHGGL
MMAR_0339|M.marinum_M LGP-------------TPDAAVLMTRDYQANPLTGRPITWHIEALDE---
MUL_4781|M.ulcerans_Agy99 LGP-------------TPDAAVLMTRDYQANPLTGRPITWHIEALDE---
MAV_5166|M.avium_104 FPP-------------TPDAAVLMTRDYQADPLTGRPVTWRIEALDE---
TH_3890|M.thermoresistible__bu LSAERPAGYDGHWFRLDPTADHVWLRQYFYDWETERP------------W
: . . : . *
Mb3561c|M.bovis_AF2122/97 TLAIARLDTVGTAPPPLTRELMEKRYATAGSQLVNR-----VKTWLQFPQ
Rv3531c|M.tuberculosis_H37Rv TLAIARLDTVGTAPPPLTRELMEKRYATAGSQLVNR-----VKTWLQFPQ
MSMEG_5932|M.smegmatis_MC2_155 HLAIARTDTAGTAPPPLTKELIEKRYAVAGKQLVQR-----VKTWLQFPQ
MAB_3969|M.abscessus_ATCC_1997 TVAISRADTLGIGAAPLTKEFVLGRYIGAGHHLINR-----VKTWLQFPQ
Mflv_4114|M.gilvum_PYR-GCK EVVPAKSDADVARSLRATLRFAQDMYALIPLILAER-----KPVELADGQ
Mvan_2231|M.vanbaalenii_PYR-1 PATPAKSDADVAKSLRASLRFAQDMYALIPLILMER-----KPVELADGQ
MMAR_0339|M.marinum_M PDPIRHADPQTAAGLRSVATWLRTMFAIMPLPVGTRDQDLPDEHALGHNT
MUL_4781|M.ulcerans_Agy99 PDPIRHADPQTAAGLRSVATWLRTMFAIMPLPVGTRDQDLPDEHALGHNT
MAV_5166|M.avium_104 PAPIRHGDAETAARLRAVATWLRTMFAIVPLAVGNR---VDDQHALGHET
TH_3890|M.thermoresistible__bu SVTIERLDVAPTDPPKPALRDVEIN------GFVDR----YVSMWQSHVA
: * . *
Mb3561c|M.bovis_AF2122/97 WFYLNIPVNTMVAPRLTPGG-LATQYSSAGHFELRPGQALVITVPVSD-A
Rv3531c|M.tuberculosis_H37Rv WFYLNIPVNTMVAPRLTPGG-LATQYSSAGHFELRPGQALVITVPVSD-A
MSMEG_5932|M.smegmatis_MC2_155 WFYNNLPVNTMVAPRLTPGG-LATQYSSVGHFDLRPDQAMVITLPVTD-A
MAB_3969|M.abscessus_ATCC_1997 WFYMNNPPNVFEPPRITPGG-LSSQFSSVGYFELEPGQALMVTVPKSD-A
Mflv_4114|M.gilvum_PYR-GCK SLSLNTLAPPYRAGAATHGFSMQDACYSLGGFSLEPGEALVITSTHPR-C
Mvan_2231|M.vanbaalenii_PYR-1 SLSLNTLAPPYRAGAATHGYSMQDACYCLGGFSLEPGEALVITSKHPK-C
MMAR_0339|M.marinum_M AHAANQFADPYQVPDANFGWSARDACYCYGSFVLDDDEALVITHRPPS-C
MUL_4781|M.ulcerans_Agy99 AHAANQFADPYQVPDANFGWSARDACYCYGSFVLDD-EALVITHRLPS-C
MAV_5166|M.avium_104 AHAANAFADPYQVPDANFGWSARDACYSYGSFVLDDDEALVITHRPPS-C
TH_3890|M.thermoresistible__bu AMADRGYVNRLETVGLPDTTGMVAQSYFQGVYEIAEDEALLLEVRPPRRC
. * : : :*::: . .
Mb3561c|M.bovis_AF2122/97 PYLGFQLGSMWYISLDYIN---HQTSLNASQAQADPDGKVRIVVAEQNPG
Rv3531c|M.tuberculosis_H37Rv PYLGFQLGSMWYISLDYIN---HQTSLNASQAQADPDGKVRIVVAEQNPG
MSMEG_5932|M.smegmatis_MC2_155 PYLGFQLGSLWYISLDYIN---HQTSLNGTQAQEDPDGKIRIVVSDANPG
MAB_3969|M.abscessus_ATCC_1997 PYQGFQLGSMWYVSLDYIN---HQTSLNSHQSHVDPDGKIRLVISDQNPG
Mflv_4114|M.gilvum_PYR-GCK RFWNLTLWNQYMAALDVEY---GRAGINSGSAVPNSDGSVTIVVSTEQLA
Mvan_2231|M.vanbaalenii_PYR-1 RFWNLTLWNQYMAALDVEY---GRAGLNSGSAVPNSDGSVTIVVSTEQLA
MMAR_0339|M.marinum_M RFWNLVVWNQFMATCGAA---DARCSVNGHSAIANSDGSVTVVLSRGVTT
MUL_4781|M.ulcerans_Agy99 RFWNLVVWNQFMATCGAA---DARCSVNGHSAIANSDGSVTVVLSRGVTT
MAV_5166|M.avium_104 RFWNMVVWNQFMATYGAAEGPDARCSINGHSAVANSDGTVTIVLSRDRTP
TH_3890|M.thermoresistible__bu RYWSVQLTDDRYISLDWMWR---QTSLNGHQARLDPDGVFRAVISHRDPG
: .. : . : . : .:*. .: :.** . *::
Mb3561c|M.bovis_AF2122/97 VTNWVETLGHRRGFLQFRWQRVSRELTEADGPTVELVDFDAIPAALPHYQ
Rv3531c|M.tuberculosis_H37Rv VTNWVETLGHRRGFLQFRWQRVSRELTEADGPTVELVDFDAIPAALPHYQ
MSMEG_5932|M.smegmatis_MC2_155 VTNWCETLGHRKGYLQFRWQRLSRALTEADGPTVEVVDIDQVPEKLPYHE
MAB_3969|M.abscessus_ATCC_1997 VVNWIETVGHRRGFLKFRWQRTNRPILDEDGPRAEVVDFDRIKVSLPFHA
Mflv_4114|M.gilvum_PYR-GCK HPNALSTKGHPEGLMSFRWFLSDDLPER---PVAEVVPVAQAPVSVS---
Mvan_2231|M.vanbaalenii_PYR-1 HPNALSTKGHPEGLMSFRWFLADELPEH---PATTVVPVAQAPVTIS---
MMAR_0339|M.marinum_M HPNSLTTLDYPRGNLAFRWFLADGVPAR---PEVKLVKLADAPTEVA---
MUL_4781|M.ulcerans_Agy99 HPNSLATLDYPRGNLAFRWFLADGVPAR---PEVKLVKLADAPTEVA---
MAV_5166|M.avium_104 HPNSVTTLGYPRGNLAFRWFLADGVPAR---PEVELVKASDAPTAVR---
TH_3890|M.thermoresistible__bu VHNWLDAAGWTRGTILGRWNRADANPVP----SVKLVDFADLPGFLPADV
* : . .* : ** . . :* :
Mb3561c|M.bovis_AF2122/97 HNKISEDDWRARIALRQRQIATRMLG
Rv3531c|M.tuberculosis_H37Rv HNKISEDDWRARIALRQRQIATRMLG
MSMEG_5932|M.smegmatis_MC2_155 SNKISEADWRARIALRQQQIQNRMVG
MAB_3969|M.abscessus_ATCC_1997 DHIVTAQQWRSRIAARQTAVATRMLG
Mflv_4114|M.gilvum_PYR-GCK --------------------------
Mvan_2231|M.vanbaalenii_PYR-1 --------------------------
MMAR_0339|M.marinum_M --------------------------
MUL_4781|M.ulcerans_Agy99 --------------------------
MAV_5166|M.avium_104 --------------------------
TH_3890|M.thermoresistible__bu PRITSDER---RAQLRARAAAAQRMG