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MLADLTKTVIEDATSERELLEGLSVLAKVTALCTEMTVEADPQRPRFFEMSTDTRLLGGSNPDGRYLLAM IRGDRTYRVIGSRGDSAYLGFQVLAGSGMNPRRMAAYLSDRELHCSRGTFNFLLSAHEPAPEVLGAAQWV QIPADATSIVVREYIADFDSELAAMMTIECLDSRPAEPLSDPALAETFTAMAWTIVKLTTLHRTIKPELL TRPNVLVTAEAAELGSADTTPDNLYMIGSFALDSDETLVLEFTPPDTRYWNVALESVWHECVAPRRQGGS VTNAGVRPDSAGQVRIAIGARDFGHGHWLDTGGRRRGFVVVRWLDNPQAPTVRSTVVRGAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4073 | - | - | 100% (341) | hypothetical protein Mflv_4073 |
| M. gilvum PYR-GCK | Mflv_4114 | - | 5e-22 | 25.87% (344) | hypothetical protein Mflv_4114 |
| M. gilvum PYR-GCK | Mflv_4383 | - | 2e-19 | 27.48% (353) | hypothetical protein Mflv_4383 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3561c | - | 1e-17 | 24.63% (337) | hypothetical protein Mb3561c |
| M. tuberculosis H37Rv | Rv3531c | - | 1e-17 | 24.63% (337) | hypothetical protein Rv3531c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4179c | - | 8e-22 | 23.92% (347) | hypothetical protein MAB_4179c |
| M. marinum M | MMAR_0221 | - | 1e-119 | 61.31% (336) | hypothetical protein MMAR_0221 |
| M. avium 104 | MAV_5268 | - | 1e-129 | 65.48% (336) | hypothetical protein MAV_5268 |
| M. smegmatis MC2 155 | MSMEG_5932 | - | 1e-16 | 23.41% (346) | hypothetical protein MSMEG_5932 |
| M. thermoresistible (build 8) | TH_3890 | - | 3e-17 | 26.88% (320) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4893 | - | 1e-118 | 61.61% (336) | hypothetical protein MUL_4893 |
| M. vanbaalenii PYR-1 | Mvan_2269 | - | 1e-155 | 77.06% (340) | hypothetical protein Mvan_2269 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4073|M.gilvum_PYR-GCK ------------------------MLADLTKTVIEDATSERELLEG-LSV
Mvan_2269|M.vanbaalenii_PYR-1 -----------MAASLQSWQFVQQMLADLTTTVIQDATSERELLEG-LAV
MMAR_0221|M.marinum_M MSHHLARPVADAPQALAAWQFFQRMLADVTKIVTEDAESEPELLEG-LRV
MUL_4893|M.ulcerans_Agy99 ------------------------MLADVTKIVTEDAESEPELLEG-LRV
MAV_5268|M.avium_104 MVHTPGSPDQAAPKARDAWQFFQRMLADVTAIVTEDAETERELAEG-LRV
Mb3561c|M.bovis_AF2122/97 --------------MYSDPLREAIAEAEQLVAAAPHIETEADLLEG-LQY
Rv3531c|M.tuberculosis_H37Rv --------------MYSDPLREAIAEAEQLVAAAPHIETEADLLEG-LQY
MSMEG_5932|M.smegmatis_MC2_155 --------------MYSQPLVDAIAEAERLVAAAPFIESEADLTEG-LQY
MAB_4179c|M.abscessus_ATCC_199 --------------MYSEAFTAAIVEAEELIVAAPHIETEADLLEG-LQY
TH_3890|M.thermoresistible__bu ------------------------MTGTATAVLAPPGNIGAATPEGDNIA
. **
Mflv_4073|M.gilvum_PYR-GCK LAKVTALCTEMTVEADPQRPRFFEMSTDTRLLGGSNPDGRYLLAMIRGDR
Mvan_2269|M.vanbaalenii_PYR-1 IAKTTALCAEMTVEADAQRPRFFDMCTETRLIGGPNPDGRYLLAMIRGDR
MMAR_0221|M.marinum_M IARVSSLCAQMSVESDPARPVFFDMCPPNRMIGGPNPEGNYFLAMIRGDH
MUL_4893|M.ulcerans_Agy99 IARVSSLCAQMSVESDPARPVFFDMCPPNRMIGGPNPEGNYFLAMIRGDH
MAV_5268|M.avium_104 VARVSSLCAQMTVEADPERPSFFDMCSDNRMVGGPNPDGNYYLAMIRGDR
Mb3561c|M.bovis_AF2122/97 LAGCIAGCMHLAFDYERDHPFLQSGTGPFTKMGLDNPDTLYFGTRLQANR
Rv3531c|M.tuberculosis_H37Rv LAGCIAGCMHLAFDYERDHPFLQSGTGPFTKMGLDNPDTLYFGTRLQANR
MSMEG_5932|M.smegmatis_MC2_155 LAGCVSGCLHLAFDYDRDHPFLQSGTGPFTKMGLDNPDTLYFGTRVQPGH
MAB_4179c|M.abscessus_ATCC_199 LAQGIAACTHMAFHTDRDHPFLLSGTGPFTKMGLDNPDTLYFGARVSGEY
TH_3890|M.thermoresistible__bu EMMALAQAQLLQQAADLVRPVWVPFLSKTIRSAGANADTTYGVALLEPGG
: . : : :* . *.: * : :
Mflv_4073|M.gilvum_PYR-GCK TYRVIGSRGDSAYLGFQVLAG---SGMNPRRMAAYLSDRELHCS-RGTFN
Mvan_2269|M.vanbaalenii_PYR-1 TYRVTGNRGSSAYLGFQVLAG---TGLTPRRMACYLGDRELVCE-GGSFD
MMAR_0221|M.marinum_M RYRITGTRGTSCYLGIQILAG---TGLTPRRMAGYLSDADLALQ-SGEFT
MUL_4893|M.ulcerans_Agy99 RYRITGTRGTSCYLGIQILAG---TGLTPRRMAGYLSDADLALQ-SGEFT
MAV_5268|M.avium_104 RYRITGTRGTSAYLGFQILAG---TGLTPRRMAGYLSDADLASE-AGEFA
Mb3561c|M.bovis_AF2122/97 DYVVSGRRGTTTDLSFQLLGG-EYTDYNVPASQAAFDDRELDIAADGSFE
Rv3531c|M.tuberculosis_H37Rv DYVVSGRRGTTTDLSFQLLGG-EYTDYNVPASQAAFDDRELDIAADGSFE
MSMEG_5932|M.smegmatis_MC2_155 EYVVTGKRGTTTDLSFQVLGG-EYTDDNVPASQAAFDDRELDIAEDGTFE
MAB_4179c|M.abscessus_ATCC_199 EYVVTGKRGTTTDLSFQVLGGGDYTDKNVPGSAIAFDDREIHIDSDGSFE
TH_3890|M.thermoresistible__bu SYRISGRRGTVVFADLLVGAGLLGVVERQQPNVGVVDFTDLDLGDDDTVE
* : * ** .: : .* .. :: . .
Mflv_4073|M.gilvum_PYR-GCK FLLSAHEPAPEVLGAAQWVQIPADATSIVVREYIADFDSEL--AAMMTIE
Mvan_2269|M.vanbaalenii_PYR-1 FLLSATRPAPETLGSAQWLQIPDDASSIVVREYIGDREAET--PASMSVE
MMAR_0221|M.marinum_M LLLSALEPD--EPGGGQWVQIPDDASAIVVREYVGDRSREE--LAKMRIE
MUL_4893|M.ulcerans_Agy99 LLLSALEPG--ELGGGQWVQIPDDASAIVVREYVGDRNHEE--LAKMRIE
MAV_5268|M.avium_104 LLLSADEPS--DPAGAQWVKIPPDASSVVVREYIGDRAAEQ--LAALRIE
Mb3561c|M.bovis_AF2122/97 WRLRPS-----------------APGQLVIREVYGDWSQQRGTLAIARLD
Rv3531c|M.tuberculosis_H37Rv WRLRPS-----------------APGQLVIREVYGDWSQQRGTLAIARLD
MSMEG_5932|M.smegmatis_MC2_155 WRITPT-----------------SPSQLVIREVYNDWSAQRGHLAIARTD
MAB_4179c|M.abscessus_ATCC_199 VRFGPAPAD---DSRPNYFTLGPGPAQLVMREVYSDWREQRGSLAIARVD
TH_3890|M.thermoresistible__bu LILSAERPAG---YDGHWFRLDPTADHVWLRQYFYDWETER--PWSVTIE
: . . : :*: * : :
Mflv_4073|M.gilvum_PYR-GCK CLDSRPAEPLSDPALAETFTAMAWTIVKLTTLHRTIKPELLTRPNVLVTA
Mvan_2269|M.vanbaalenii_PYR-1 CVDADPLQPISDEALAAAFTAMAWTIVKLATLHRTVKPELLTAPNVLVTA
MMAR_0221|M.marinum_M AFAPAPASPPTDDELAGQFTALAWSLMKLTTLHRTIKPELLDHPNTLLTA
MUL_4893|M.ulcerans_Agy99 AFDPAPASPPTDDELAGQFTALAWSLMKLTTLHRTIKPELLDHPNTLLTA
MAV_5268|M.avium_104 ALDPGPLTPLTDEQLADQFTAMAWSLMKLATLHRTIKPELLQSPNTLLTA
Mb3561c|M.bovis_AF2122/97 TVGTAPP-PLTRELMEKRYATAGSQLVNRVKTWLQFPQWFYL--NIPVNT
Rv3531c|M.tuberculosis_H37Rv TVGTAPP-PLTRELMEKRYATAGSQLVNRVKTWLQFPQWFYL--NIPVNT
MSMEG_5932|M.smegmatis_MC2_155 TAGTAPP-PLTKELIEKRYAVAGKQLVQRVKTWLQFPQWFYN--NLPVNT
MAB_4179c|M.abscessus_ATCC_199 TAGTAPA-PLTKEQIEKRYASAGKQLVNRVKTWLQFPKWFYD--NLPVNT
TH_3890|M.thermoresistible__bu RLDVAPTDPPKPALRDVEINGFVDRYVSMWQSHVAA----MADRGYVNRL
* * . :. .
Mflv_4073|M.gilvum_PYR-GCK EAAELGSADTTPDNLYMIGSFALDSDETLVLEFTPPD-TRYWNVALESVW
Mvan_2269|M.vanbaalenii_PYR-1 EAAELGSAETTPDNLYMIGSFALEADETLLLEFTPPD-TRYWNVTLENVW
MMAR_0221|M.marinum_M QAADLGAADTTPDNLYMIGTFRLAPGQALVLDFEPPE-TRYWSVALESIW
MUL_4893|M.ulcerans_Agy99 RAADLGAADTTPDNLYMIGTFRLAPGQALVLDFEPPE-TRYWSVALESIW
MAV_5268|M.avium_104 QAADLGEADTTPDNLYMVGSFRLDPGQALVLDIAPPD-TRYWNVTLESIW
Mb3561c|M.bovis_AF2122/97 MVAPRLTPGGLATQYSSAGHFELRPGQALVITVPVSD-APYLGFQLGSMW
Rv3531c|M.tuberculosis_H37Rv MVAPRLTPGGLATQYSSAGHFELRPGQALVITVPVSD-APYLGFQLGSMW
MSMEG_5932|M.smegmatis_MC2_155 MVAPRLTPGGLATQYSSVGHFDLRPDQAMVITLPVTD-APYLGFQLGSLW
MAB_4179c|M.abscessus_ATCC_199 MTEPRLTPGGLATQFSSVGHYDLADDQAMIITVPKSD-APYQGFQLGSLW
TH_3890|M.thermoresistible__bu ETVGLPDTTGMVAQSYFQGVYEIAEDEALLLEVRPPRRCRYWSVQLTDDR
. . : * : : .::::: . . * .. * .
Mflv_4073|M.gilvum_PYR-GCK HECVAPRRQGGSVTNAGVRPDSAGQVRIAIGARDFGHGHWLDTGGRRRGF
Mvan_2269|M.vanbaalenii_PYR-1 HECLEPRHRHSSVTNMGVLPDPAGVVRIAVSGKDFGHGHWLDTGGRHRGF
MMAR_0221|M.marinum_M HECLEPDSRHSSVTNRAVRPGADGRVRIAISEQDLGFGHWLDTGGRHRGF
MUL_4893|M.ulcerans_Agy99 HECLEPDSRHSSVTNRAVRAGADGRVCIAISEQDFGFGHWLDTGGRHRGF
MAV_5268|M.avium_104 HECLEPRRRHSSVTNRGVRPDADGRVRIAISARDFGFGHWLDTGGRHRGF
Mb3561c|M.bovis_AF2122/97 YISLDYINHQTSLNASQAQADPDGKVRIVVAEQNPGVTNWVETLGHRRGF
Rv3531c|M.tuberculosis_H37Rv YISLDYINHQTSLNASQAQADPDGKVRIVVAEQNPGVTNWVETLGHRRGF
MSMEG_5932|M.smegmatis_MC2_155 YISLDYINHQTSLNGTQAQEDPDGKIRIVVSDANPGVTNWCETLGHRKGY
MAB_4179c|M.abscessus_ATCC_199 YISLDYINHQTSLNSSQAQIDPDGNIRMVVSNTNPGVTNWIETLGHRRAY
TH_3890|M.thermoresistible__bu YISLDWMWRQTSLNGHQARLDPDGVFRAVISHRDPGVHNWLDAAGWTRGT
: .: : *:. . .. * . .:. : * :* :: * :.
Mflv_4073|M.gilvum_PYR-GCK VVVRWLDNP------QAPTVRSTVVRGAP---------------------
Mvan_2269|M.vanbaalenii_PYR-1 VVVRWLDNP------AAPVVRTTVRRGAGS--------------------
MMAR_0221|M.marinum_M VILRWLDNP------QAPDIEVSVRHREQRA-------------------
MUL_4893|M.ulcerans_Agy99 VILRCLDNP------QAPDVEVSVRHREQRA-------------------
MAV_5268|M.avium_104 VVLRWLDNP------SPPEVAVSVREARERP-------------------
Mb3561c|M.bovis_AF2122/97 LQFRWQRVSRELTEADGPTVELVDFDAIPAALPHYQHNKISEDDWRARIA
Rv3531c|M.tuberculosis_H37Rv LQFRWQRVSRELTEADGPTVELVDFDAIPAALPHYQHNKISEDDWRARIA
MSMEG_5932|M.smegmatis_MC2_155 LQFRWQRLSRALTEADGPTVEVVDIDQVPEKLPYHESNKISEADWRARIA
MAB_4179c|M.abscessus_ATCC_199 LQFRWQRADRQLTPADGPTVEVVAVGDIPAKLPHYSQNQISEEGWRSRIA
TH_3890|M.thermoresistible__bu ILGRWNRADAN----PVPSVKLVDFADLPGFLPADVPRITSDER---RAQ
: * * :
Mflv_4073|M.gilvum_PYR-GCK ------------
Mvan_2269|M.vanbaalenii_PYR-1 ------------
MMAR_0221|M.marinum_M ------------
MUL_4893|M.ulcerans_Agy99 ------------
MAV_5268|M.avium_104 ------------
Mb3561c|M.bovis_AF2122/97 LRQRQIATRMLG
Rv3531c|M.tuberculosis_H37Rv LRQRQIATRMLG
MSMEG_5932|M.smegmatis_MC2_155 LRQQQIQNRMVG
MAB_4179c|M.abscessus_ATCC_199 ERQTAIGARMLG
TH_3890|M.thermoresistible__bu LRARAAAAQRMG