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SHHLARPVADAPQALAAWQFFQRMLADVTKIVTEDAESEPELLEGLRVIARVSSLCAQMSVESDPARPVF FDMCPPNRMIGGPNPEGNYFLAMIRGDHRYRITGTRGTSCYLGIQILAGTGLTPRRMAGYLSDADLALQS GEFTLLLSALEPDEPGGGQWVQIPDDASAIVVREYVGDRSREELAKMRIEAFAPAPASPPTDDELAGQFT ALAWSLMKLTTLHRTIKPELLDHPNTLLTAQAADLGAADTTPDNLYMIGTFRLAPGQALVLDFEPPETRY WSVALESIWHECLEPDSRHSSVTNRAVRPGADGRVRIAISEQDLGFGHWLDTGGRHRGFVILRWLDNPQA PDIEVSVRHREQRA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0221 | - | - | 100% (365) | hypothetical protein MMAR_0221 |
| M. marinum M | MMAR_5019 | - | 3e-24 | 26.61% (342) | hypothetical protein MMAR_5019 |
| M. marinum M | MMAR_0339 | - | 6e-15 | 24.01% (354) | hypothetical protein MMAR_0339 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3561c | - | 4e-24 | 27.24% (312) | hypothetical protein Mb3561c |
| M. gilvum PYR-GCK | Mflv_4073 | - | 1e-119 | 61.31% (336) | hypothetical protein Mflv_4073 |
| M. tuberculosis H37Rv | Rv3531c | - | 4e-24 | 27.24% (312) | hypothetical protein Rv3531c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4179c | - | 3e-25 | 25.30% (332) | hypothetical protein MAB_4179c |
| M. avium 104 | MAV_5268 | - | 1e-165 | 76.52% (362) | hypothetical protein MAV_5268 |
| M. smegmatis MC2 155 | MSMEG_5932 | - | 2e-23 | 27.27% (330) | hypothetical protein MSMEG_5932 |
| M. thermoresistible (build 8) | TH_0374 | - | 1e-25 | 26.02% (342) | HYPOTHETICAL PROTEIN Rv3531c |
| M. ulcerans Agy99 | MUL_4893 | - | 0.0 | 96.77% (341) | hypothetical protein MUL_4893 |
| M. vanbaalenii PYR-1 | Mvan_2269 | - | 1e-128 | 61.96% (347) | hypothetical protein Mvan_2269 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5932|M.smegmatis_MC2_155 --------------MYSQPLVDAIAEAERLVAAAPFIESEADLTEGLQYL
TH_0374|M.thermoresistible__bu --------------MYSQPLLDAIAEAERIVTEAPHIETEADLLEGLHYL
Mb3561c|M.bovis_AF2122/97 --------------MYSDPLREAIAEAEQLVAAAPHIETEADLLEGLQYL
Rv3531c|M.tuberculosis_H37Rv --------------MYSDPLREAIAEAEQLVAAAPHIETEADLLEGLQYL
MAB_4179c|M.abscessus_ATCC_199 --------------MYSEAFTAAIVEAEELIVAAPHIETEADLLEGLQYL
MMAR_0221|M.marinum_M MSHHLARPVADAPQALAAWQFFQRMLADVTKIVTEDAESEPELLEGLRVI
MUL_4893|M.ulcerans_Agy99 ------------------------MLADVTKIVTEDAESEPELLEGLRVI
MAV_5268|M.avium_104 MVHTPGSPDQAAPKARDAWQFFQRMLADVTAIVTEDAETERELAEGLRVV
Mflv_4073|M.gilvum_PYR-GCK ------------------------MLADLTKTVIEDATSERELLEGLSVL
Mvan_2269|M.vanbaalenii_PYR-1 -----------MAASLQSWQFVQQMLADLTTTVIQDATSERELLEGLAVI
*: :* :* *** :
MSMEG_5932|M.smegmatis_MC2_155 AGCVSGCLHLAFDYDRDHPFLQSGTGPFTKMGLDNPDTLYFGTRVQPGHE
TH_0374|M.thermoresistible__bu AGCISACIHLAFDYERDHPFLQSGTGPFTKMGLDNPDTLYFGTRVLPGHE
Mb3561c|M.bovis_AF2122/97 AGCIAGCMHLAFDYERDHPFLQSGTGPFTKMGLDNPDTLYFGTRLQANRD
Rv3531c|M.tuberculosis_H37Rv AGCIAGCMHLAFDYERDHPFLQSGTGPFTKMGLDNPDTLYFGTRLQANRD
MAB_4179c|M.abscessus_ATCC_199 AQGIAACTHMAFHTDRDHPFLLSGTGPFTKMGLDNPDTLYFGARVSGEYE
MMAR_0221|M.marinum_M ARVSSLCAQMSVESDPARPVFFDMCPPNRMIGGPNPEGNYFLAMIRGDHR
MUL_4893|M.ulcerans_Agy99 ARVSSLCAQMSVESDPARPVFFDMCPPNRMIGGPNPEGNYFLAMIRGDHR
MAV_5268|M.avium_104 ARVSSLCAQMTVEADPERPSFFDMCSDNRMVGGPNPDGNYYLAMIRGDRR
Mflv_4073|M.gilvum_PYR-GCK AKVTALCTEMTVEADPQRPRFFEMSTDTRLLGGSNPDGRYLLAMIRGDRT
Mvan_2269|M.vanbaalenii_PYR-1 AKTTALCAEMTVEADAQRPRFFDMCTETRLIGGPNPDGRYLLAMIRGDRT
* : * .::.. : :* : . :* **: * : :
MSMEG_5932|M.smegmatis_MC2_155 YVVTGKRGTTTDLSFQVLGG-EYTDDNVPASQAAFDDRELDIAEDGTFEW
TH_0374|M.thermoresistible__bu YVVTGTRGTTTDLSFQLLGG-EYTDEGVPESQAAFDDRELDIGEDGRFEW
Mb3561c|M.bovis_AF2122/97 YVVSGRRGTTTDLSFQLLGG-EYTDYNVPASQAAFDDRELDIAADGSFEW
Rv3531c|M.tuberculosis_H37Rv YVVSGRRGTTTDLSFQLLGG-EYTDYNVPASQAAFDDRELDIAADGSFEW
MAB_4179c|M.abscessus_ATCC_199 YVVTGKRGTTTDLSFQVLGGGDYTDKNVPGSAIAFDDREIHIDSDGSFEV
MMAR_0221|M.marinum_M YRITGTRGTSCYLGIQILAG---TGLTPRRMAGYLSDADLALQS-GEFTL
MUL_4893|M.ulcerans_Agy99 YRITGTRGTSCYLGIQILAG---TGLTPRRMAGYLSDADLALQS-GEFTL
MAV_5268|M.avium_104 YRITGTRGTSAYLGFQILAG---TGLTPRRMAGYLSDADLASEA-GEFAL
Mflv_4073|M.gilvum_PYR-GCK YRVIGSRGDSAYLGFQVLAG---SGMNPRRMAAYLSDRELHCSR-GTFNF
Mvan_2269|M.vanbaalenii_PYR-1 YRVTGNRGSSAYLGFQVLAG---TGLTPRRMACYLGDRELVCEG-GSFDF
* : * ** : *.:*:*.* :. :.* :: * *
MSMEG_5932|M.smegmatis_MC2_155 RITPT-----------------SPSQLVIREVYNDWSAQRGHLAIARTDT
TH_0374|M.thermoresistible__bu RFTPE-----------------QPSQLVIREVYGDWSQQRGTIAIARTDT
Mb3561c|M.bovis_AF2122/97 RLRPS-----------------APGQLVIREVYGDWSQQRGTLAIARLDT
Rv3531c|M.tuberculosis_H37Rv RLRPS-----------------APGQLVIREVYGDWSQQRGTLAIARLDT
MAB_4179c|M.abscessus_ATCC_199 RFGPAPAD---DSRPNYFTLGPGPAQLVMREVYSDWREQRGSLAIARVDT
MMAR_0221|M.marinum_M LLSALEPD--EPGGGQWVQIPDDASAIVVREYVGDRSREELAKMRIEAFA
MUL_4893|M.ulcerans_Agy99 LLSALEPG--ELGGGQWVQIPDDASAIVVREYVGDRNHEELAKMRIEAFD
MAV_5268|M.avium_104 LLSADEPS--DPAGAQWVKIPPDASSVVVREYIGDRAAEQLAALRIEALD
Mflv_4073|M.gilvum_PYR-GCK LLSAHEPAPEVLGAAQWVQIPADATSIVVREYIADFDSELAAMMTIECLD
Mvan_2269|M.vanbaalenii_PYR-1 LLSATRPAPETLGSAQWLQIPDDASSIVVREYIGDREAETPASMSVECVD
: . . :*:** * : .
MSMEG_5932|M.smegmatis_MC2_155 AGTAPPPLTKELIEKRYAVAGKQLVQRVKTWLQFPQWFYNNLPVNTMVAP
TH_0374|M.thermoresistible__bu AGTAPPPPTRRTIEKRYAVAGRQLVQRVKTWLQFPQWFYFNIPVNTMVPP
Mb3561c|M.bovis_AF2122/97 VGTAPPPLTRELMEKRYATAGSQLVNRVKTWLQFPQWFYLNIPVNTMVAP
Rv3531c|M.tuberculosis_H37Rv VGTAPPPLTRELMEKRYATAGSQLVNRVKTWLQFPQWFYLNIPVNTMVAP
MAB_4179c|M.abscessus_ATCC_199 AGTAPAPLTKEQIEKRYASAGKQLVNRVKTWLQFPKWFYDNLPVNTMTEP
MMAR_0221|M.marinum_M PAPASPPTDDELAGQFTALAWSLMKLTTLHRTIKPELLDHPNTLLTAQAA
MUL_4893|M.ulcerans_Agy99 PAPASPPTDDELAGQFTALAWSLMKLTTLHRTIKPELLDHPNTLLTARAA
MAV_5268|M.avium_104 PGPLTPLTDEQLADQFTAMAWSLMKLATLHRTIKPELLQSPNTLLTAQAA
Mflv_4073|M.gilvum_PYR-GCK SRPAEPLSDPALAETFTAMAWTIVKLTTLHRTIKPELLTRPNVLVTAEAA
Mvan_2269|M.vanbaalenii_PYR-1 ADPLQPISDEALAAAFTAMAWTIVKLATLHRTVKPELLTAPNVLVTAEAA
. . * * : . *: : : * .
MSMEG_5932|M.smegmatis_MC2_155 RLTPGG-LATQYSSVGHFDLRPDQAMVITLPVTDAPYLGFQLGSLWYISL
TH_0374|M.thermoresistible__bu RLTPGG-LSTQYSSAGHYELEPDQAMIITVPVSDAPYLGFQLGSLWYISL
Mb3561c|M.bovis_AF2122/97 RLTPGG-LATQYSSAGHFELRPGQALVITVPVSDAPYLGFQLGSMWYISL
Rv3531c|M.tuberculosis_H37Rv RLTPGG-LATQYSSAGHFELRPGQALVITVPVSDAPYLGFQLGSMWYISL
MAB_4179c|M.abscessus_ATCC_199 RLTPGG-LATQFSSVGHYDLADDQAMIITVPKSDAPYQGFQLGSLWYISL
MMAR_0221|M.marinum_M DLGAADTTPDNLYMIGTFRLAPGQALVLDFEPPETRYWSVALESIWHECL
MUL_4893|M.ulcerans_Agy99 DLGAADTTPDNLYMIGTFRLAPGQALVLDFEPPETRYWSVALESIWHECL
MAV_5268|M.avium_104 DLGEADTTPDNLYMVGSFRLDPGQALVLDIAPPDTRYWNVTLESIWHECL
Mflv_4073|M.gilvum_PYR-GCK ELGSADTTPDNLYMIGSFALDSDETLVLEFTPPDTRYWNVALESVWHECV
Mvan_2269|M.vanbaalenii_PYR-1 ELGSAETTPDNLYMIGSFALEADETLLLEFTPPDTRYWNVTLENVWHECL
* . . : * : * .::::: . .:: * .. * .:*: .:
MSMEG_5932|M.smegmatis_MC2_155 DYINHQTSLNGTQAQEDPDGKIRIVVSDANPGVTNWCETLGHRKGYLQFR
TH_0374|M.thermoresistible__bu DYINHQTSLNATQAQADPDGRIRIVVSEANPGVTNWVETLGHRRGIMQFR
Mb3561c|M.bovis_AF2122/97 DYINHQTSLNASQAQADPDGKVRIVVAEQNPGVTNWVETLGHRRGFLQFR
Rv3531c|M.tuberculosis_H37Rv DYINHQTSLNASQAQADPDGKVRIVVAEQNPGVTNWVETLGHRRGFLQFR
MAB_4179c|M.abscessus_ATCC_199 DYINHQTSLNSSQAQIDPDGNIRMVVSNTNPGVTNWIETLGHRRAYLQFR
MMAR_0221|M.marinum_M EPDSRHSSVTNRAVRPGADGRVRIAISEQDLGFGHWLDTGGRHRGFVILR
MUL_4893|M.ulcerans_Agy99 EPDSRHSSVTNRAVRAGADGRVCIAISEQDFGFGHWLDTGGRHRGFVILR
MAV_5268|M.avium_104 EPRRRHSSVTNRGVRPDADGRVRIAISARDFGFGHWLDTGGRHRGFVVLR
Mflv_4073|M.gilvum_PYR-GCK APRRQGGSVTNAGVRPDSAGQVRIAIGARDFGHGHWLDTGGRRRGFVVVR
Mvan_2269|M.vanbaalenii_PYR-1 EPRHRHSSVTNMGVLPDPAGVVRIAVSGKDFGHGHWLDTGGRHRGFVVVR
: *:. . .. * : :.:. : * :* :* *:::. : .*
MSMEG_5932|M.smegmatis_MC2_155 WQRLSRALTEADGPTVEVVDIDQVPEKLPYHESNKISEADWRARIALRQQ
TH_0374|M.thermoresistible__bu WQRVSRPLTEADGPTVEVVDFDQVPAALPYYESNRISEEAWRARIAQRQI
Mb3561c|M.bovis_AF2122/97 WQRVSRELTEADGPTVELVDFDAIPAALPHYQHNKISEDDWRARIALRQR
Rv3531c|M.tuberculosis_H37Rv WQRVSRELTEADGPTVELVDFDAIPAALPHYQHNKISEDDWRARIALRQR
MAB_4179c|M.abscessus_ATCC_199 WQRADRQLTPADGPTVEVVAVGDIPAKLPHYSQNQISEEGWRSRIAERQT
MMAR_0221|M.marinum_M WLDNP------QAPDIEVSVRHREQRA-----------------------
MUL_4893|M.ulcerans_Agy99 CLDNP------QAPDVEVSVRHREQRA-----------------------
MAV_5268|M.avium_104 WLDNP------SPPEVAVSVREARERP-----------------------
Mflv_4073|M.gilvum_PYR-GCK WLDNP------QAPTVRSTVVRGAP-------------------------
Mvan_2269|M.vanbaalenii_PYR-1 WLDNP------AAPVVRTTVRRGAGS------------------------
* :
MSMEG_5932|M.smegmatis_MC2_155 QIQNRMVG
TH_0374|M.thermoresistible__bu QIANRMLG
Mb3561c|M.bovis_AF2122/97 QIATRMLG
Rv3531c|M.tuberculosis_H37Rv QIATRMLG
MAB_4179c|M.abscessus_ATCC_199 AIGARMLG
MMAR_0221|M.marinum_M --------
MUL_4893|M.ulcerans_Agy99 --------
MAV_5268|M.avium_104 --------
Mflv_4073|M.gilvum_PYR-GCK --------
Mvan_2269|M.vanbaalenii_PYR-1 --------