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LSEPRREYSDVPNMIRALRQLDPASPEYRRLHERIIAMTLPLAQHTARRFRGRGQSHDDLFQVASVGLVN AVKRFDPDSGSDFLAYAVPTIMGEVRRYFRDCSWAVKVPRRLKDLNSQLAKARAELTQQLGRAPTPSEVA AHLGIDREEVVQATIASSNYATLSTDSTSGPDGDFVALRETLGEPDARLDAVVDNETIRPLIEKLPPREQ AVLKLRFFDEMTQTQIAERMGYSQMHVSRLLAKALATLRDQALSDGTAADFVPSRSGRVA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3872 | - | - | 100% (270) | FliA/WhiG family RNA polymerase sigma factor |
| M. gilvum PYR-GCK | Mflv_3871 | - | 1e-81 | 60.24% (254) | FliA/WhiG family RNA polymerase sigma factor |
| M. gilvum PYR-GCK | Mflv_4789 | - | 4e-79 | 60.16% (251) | RNA polymerase sigma factor SigF |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3314c | sigF | 3e-82 | 62.04% (245) | RNA polymerase sigma factor SigF |
| M. tuberculosis H37Rv | Rv3286c | sigF | 3e-82 | 62.04% (245) | RNA polymerase sigma factor SigF |
| M. leprae Br4923 | MLBr_01022 | rpoT | 1e-21 | 28.21% (234) | RNA polymerase sigma factor |
| M. abscessus ATCC 19977 | MAB_2511 | - | 6e-67 | 51.19% (252) | RNA polymerase sigma factor SigF |
| M. marinum M | MMAR_1248 | sigF | 9e-82 | 63.01% (246) | alternate RNA polymerase sigma factor SigF |
| M. avium 104 | MAV_4256 | - | 3e-76 | 60.67% (239) | RNA polymerase sigma factor SigF |
| M. smegmatis MC2 155 | MSMEG_1804 | - | 2e-78 | 61.22% (245) | RNA polymerase sigma factor SigF |
| M. thermoresistible (build 8) | TH_0241 | sigF | 1e-75 | 60.00% (240) | ALTERNATE RNA POLYMERASE SIGMA FACTOR SIGF |
| M. ulcerans Agy99 | MUL_2640 | sigF | 6e-82 | 63.01% (246) | RNA polymerase sigma factor SigF |
| M. vanbaalenii PYR-1 | Mvan_2531 | - | 2e-78 | 60.00% (240) | FliA/WhiG family RNA polymerase sigma factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2531|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3314c|M.bovis_AF2122/97 --------------------------------------------------
Rv3286c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1248|M.marinum_M --------------------------------------------------
MUL_2640|M.ulcerans_Agy99 --------------------------------------------------
MAV_4256|M.avium_104 --------------------------------------------------
TH_0241|M.thermoresistible__bu --------------------------------------------------
MSMEG_1804|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2511|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01022|M.leprae_Br4923 MEQSRRVPPLQWLSAVARPIARVLTLISTPTFDIADTFGYACPNPPEVSP
Mflv_3872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2531|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3314c|M.bovis_AF2122/97 --------------------------------------------------
Rv3286c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1248|M.marinum_M --------------------------------------------------
MUL_2640|M.ulcerans_Agy99 --------------------------------------------------
MAV_4256|M.avium_104 --------------------------------------------------
TH_0241|M.thermoresistible__bu --------------------------------------------------
MSMEG_1804|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2511|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01022|M.leprae_Br4923 TEGVYVVATKTSPATGQPVKRTATKTPATPAKRSTTKAANGSAPTKRATS
Mflv_3872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2531|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3314c|M.bovis_AF2122/97 --------------------------------------------------
Rv3286c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1248|M.marinum_M --------------------------------------------------
MUL_2640|M.ulcerans_Agy99 --------------------------------------------------
MAV_4256|M.avium_104 --------------------------------------------------
TH_0241|M.thermoresistible__bu --------------------------------------------------
MSMEG_1804|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2511|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01022|M.leprae_Br4923 TASRATKSTTPPKASGASDAAKKARTSVKSVDTKAPSAQDHTTKASAAKD
Mflv_3872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2531|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3314c|M.bovis_AF2122/97 --------------------------------------------------
Rv3286c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1248|M.marinum_M --------------------------------------------------
MUL_2640|M.ulcerans_Agy99 --------------------------------------------------
MAV_4256|M.avium_104 --------------------------------------------------
TH_0241|M.thermoresistible__bu --------------------------------------------------
MSMEG_1804|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2511|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01022|M.leprae_Br4923 TLNDPEATLNTLDSDATADDLDAEPDLDVEPSEDIDIDIEAADLGLDDLE
Mflv_3872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2531|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3314c|M.bovis_AF2122/97 --------------------------------------------------
Rv3286c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1248|M.marinum_M --------------------------------------------------
MUL_2640|M.ulcerans_Agy99 --------------------------------------------------
MAV_4256|M.avium_104 --------------------------------------------------
TH_0241|M.thermoresistible__bu --------------------------------------------------
MSMEG_1804|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2511|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01022|M.leprae_Br4923 DDDVVTDIEPGETEDGEATAATKTDEASTDDDEEIVEPTEKDKASGDFVW
Mflv_3872|M.gilvum_PYR-GCK --------------------------------------------MSEPRR
Mvan_2531|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3314c|M.bovis_AF2122/97 ------------------------------------MTARAAGGSASRAN
Rv3286c|M.tuberculosis_H37Rv ------------------------------------MTARAAGGSASRAN
MMAR_1248|M.marinum_M ------------------------------------MTSRTAGGSSSRPN
MUL_2640|M.ulcerans_Agy99 ------------------------------------MTSRTAGGSSSRPN
MAV_4256|M.avium_104 --------------------------------------------------
TH_0241|M.thermoresistible__bu --------------------------------------------------
MSMEG_1804|M.smegmatis_MC2_155 ------------------------------------MTS-----------
MAB_2511|M.abscessus_ATCC_1997 --------------------------MECPVDVPETGHSQVKPRVGRPTD
MLBr_01022|M.leprae_Br4923 DEDESEALRQARKDAELTASADSVRAYLKQIGKVALLNAEEEVELAKRIE
Mflv_3872|M.gilvum_PYR-GCK EYSDVPNMIRALRQLDPASPEYRRL------------HERIIAMTLPLAQ
Mvan_2531|M.vanbaalenii_PYR-1 -------MFRELALLDEGSAPYRRQ------------RDAIIERCLPLAD
Mb3314c|M.bovis_AF2122/97 EYADVPEMFRELVGLPAGSPEFQRH------------RDKIVQRCLPLAD
Rv3286c|M.tuberculosis_H37Rv EYADVPEMFRELVGLPAGSPEFQRH------------RDKIVQRCLPLAD
MMAR_1248|M.marinum_M EYADVPEMFRELATFDADSPNFQRH------------RDTIVERCLPLAD
MUL_2640|M.ulcerans_Agy99 EYADVPEMFRELATFDADSPNFQRH------------RDTIVERCLPLAD
MAV_4256|M.avium_104 -------MFRELATAEPDSMEFQRQ------------RDKIVERCLPLAD
TH_0241|M.thermoresistible__bu -------MFRELRKLPAESKEFQRQ------------RDRIVERCLPLAD
MSMEG_1804|M.smegmatis_MC2_155 EYADVLDMFRELAGTTEGSPSYVRQ------------REKIVERCLPLAD
MAB_2511|M.abscessus_ATCC_1997 DYADVPDMFRSLAGLAEHSDAYQRK------------HEEIVTRCLPLAD
MLBr_01022|M.leprae_Br4923 AGLYATQLMTELSERGTKLPTAQRRDMMWICRDGDRAKNHLLEANLRLVV
:: * * :: :: * *.
Mflv_3872|M.gilvum_PYR-GCK HTARRFRGRGQSHDDLFQVASVGLVNAVKRFDPDSGSDFLAYAVPTIMGE
Mvan_2531|M.vanbaalenii_PYR-1 HIARRFRGRGEAHEDLVQVARVGLLNAVNRFDVDSANDFLAFAVPTMMGE
Mb3314c|M.bovis_AF2122/97 HIARRFEGRGEPRDDLIQVARVGLVNAAVRFDVKTGSDFVSFAVPTIMGE
Rv3286c|M.tuberculosis_H37Rv HIARRFEGRGEPRDDLIQVARVGLVNAAVRFDVKTGSDFVSFAVPTIMGE
MMAR_1248|M.marinum_M HIARRFEGRGEPRDDLVQVARVGLVNAVVRFDVETGSDFVSFAVPTIMGE
MUL_2640|M.ulcerans_Agy99 HIARRFEGRGEPRDDLVQVARVGLVNAVVRFDVETGSDFVSFAVPTIMGE
MAV_4256|M.avium_104 HIARRFEGRGEPRDDLVQVARVGLVNAVVRFDVDAGSDFVSFAVPTIMGE
TH_0241|M.thermoresistible__bu HIARRFDGRGEARDDLVQVARVGLVNAVIRFDVETGSDFVSFAVPTIMGE
MSMEG_1804|M.smegmatis_MC2_155 HIARRFDGRGEPREDLVQVARVGLVNAVNRFDVEAGSDFVSFAVPTIMGE
MAB_2511|M.abscessus_ATCC_1997 NVARHFDRRGEDLEDLIQVARVGLLNAVNRFDPEKGASFLGFAVPTMMGE
MLBr_01022|M.leprae_Br4923 SLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYTKGYKFSTYATWWIRQA
*::: ** **.* . :**:.*. :** . .* :*. :
Mflv_3872|M.gilvum_PYR-GCK VRRYFRDCSWAVKVPRRLKDLNSQLAKARAELTQQLGRAPTPSEVAAHLG
Mvan_2531|M.vanbaalenii_PYR-1 VRRYFRDHGWSLKVPRRLKELNVRLNSARSELTHQLNRAPTPSELAEFLG
Mb3314c|M.bovis_AF2122/97 VRRHFRDNSWSVKVPRRLKELHLRLGTATADLSQRLGRAPSASELAAELG
Rv3286c|M.tuberculosis_H37Rv VRRHFRDNSWSVKVPRRLKELHLRLGTATADLSQRLGRAPSASELAAELG
MMAR_1248|M.marinum_M VRRHFRDNSWSVKVPRRLKELHLRLGAATAELSQRLGRAPTATELAAELE
MUL_2640|M.ulcerans_Agy99 VRRHFRDNSWSVKVPRRLKELHLRLGAATAELSQRLGRAPTATELAAELE
MAV_4256|M.avium_104 VRRHFRDNSWSVKVPRRLKELHLRLGTATADLSQRLGRAHTATELAAELE
TH_0241|M.thermoresistible__bu VRRHFRDNSWSVKVPRRLKELHLRLGAATAELSQRLGRAPTASELAEELE
MSMEG_1804|M.smegmatis_MC2_155 VRRHFRDNSWSVKVPRRLKELHLRLGAATAELSQRLGRAPTASELAHELD
MAB_2511|M.abscessus_ATCC_1997 VRRHFRDHGWSLHVPRAIRDRHAQISRATAELTQELQRAPTAGELAAELG
MLBr_01022|M.leprae_Br4923 ITRAMADQARTIRIPVHMVEVINKLGRIQRELLQDLGREPTPEELAKEMD
: * : * . ::::* : : :: :* : * * :. *:* :
Mflv_3872|M.gilvum_PYR-GCK IDREEVVQATIASSNYATLSTDSTSG--PDGDFVALRETLGEPDAR--LD
Mvan_2531|M.vanbaalenii_PYR-1 MERDEIVEGLVAANAYSTRSTEQETMRTGDGDGLTLLDTIGGPDEG--IQ
Mb3314c|M.bovis_AF2122/97 MDRAEVIEGLLAGSSYHTLSIDSG-GGS-DDDARAITDTLGDVDAG--LD
Rv3286c|M.tuberculosis_H37Rv MDRAEVIEGLLAGSSYHTLSIDSG-GGS-DDDARAITDTLGDVDAG--LD
MMAR_1248|M.marinum_M MDRAEVVEGLVAGSSYNTLSIDSG-SGSEDDDARAIADTLGDMDAG--LD
MUL_2640|M.ulcerans_Agy99 MDRAEVVEGLVAGSSYNTLSIDSG-SGSEDDDARAIADTLGDMDAG--LD
MAV_4256|M.avium_104 MDREEVVEGLVAGSSYNTLSIDSG-GGSEEEEVRAIADTLGDVDTG--LD
TH_0241|M.thermoresistible__bu MDRDEVIEGLVAGSSYNTLSIDSGGSGSGTEDAPAIADTLGDVDTG--LD
MSMEG_1804|M.smegmatis_MC2_155 MDREEVVEGLIAGSSYNTLSIDSG--GGGDEEAPAIVDTLGDLDMG--LD
MAB_2511|M.abscessus_ATCC_1997 IDREEVVESLIAADAYQPQSIEAP-LSHGDQESKHLSDLLGNEDPA--LE
MLBr_01022|M.leprae_Br4923 ITPEKVLE--IQQYAREPISLDQTIGDEGDSQLGDFIEDSEAVVAVDAVS
: :::: : . * : : : : :.
Mflv_3872|M.gilvum_PYR-GCK AVVDNETIRPLIEKLPPREQAVLKLRFFDE----MTQTQIAERMGYSQMH
Mvan_2531|M.vanbaalenii_PYR-1 RVIDIQTVQPLLAKLPARDRLVLQLRFFDN----LTQSQIAERIGVSQMH
Mb3314c|M.bovis_AF2122/97 QIENREVLRPLLEALPERERTVLVLRFFDS----MTQTQIAERVGISQMH
Rv3286c|M.tuberculosis_H37Rv QIENREVLRPLLEALPERERTVLVLRFFDS----MTQTQIAERVGISQMH
MMAR_1248|M.marinum_M RIEDRESLRPLLEALPERERTVLVLRFFDS----MTQTQIAERVGISQMH
MUL_2640|M.ulcerans_Agy99 RIEDRESLRPLLEALPERERTVLVLRFFDS----MTQTQIAERVGISQMH
MAV_4256|M.avium_104 RIEDQESLRPLLEALPERERTVLVLRFFES----MTQTQIAERVGISQMH
TH_0241|M.thermoresistible__bu QIENREALRPLLAALPERERTVLVLRFFES----LTQTQIAERVGISQMH
MSMEG_1804|M.smegmatis_MC2_155 QIDNRESLRPLLASLPERERTVLVLRFFES----MTQTQIAERVGISQMH
MAB_2511|M.abscessus_ATCC_1997 HVTNREAVRPLLANLPLRERTVLELRFFKG----MTQSQIAAQIGVSQMH
MLBr_01022|M.leprae_Br4923 FTLLQDQLQSVLETLSEREAGVVRLRFGLTDGQPRTLDEIGQVYGVTRER
: ::.:: *. *: *: *** * :*. * :: :
Mflv_3872|M.gilvum_PYR-GCK VSRLLAKALATLRDQALSDGTAADFVPSRSGRVA
Mvan_2531|M.vanbaalenii_PYR-1 VSRLLARALATLREQIG-----------------
Mb3314c|M.bovis_AF2122/97 VSRLLAKSLARLRDQLE-----------------
Rv3286c|M.tuberculosis_H37Rv VSRLLAKSLARLRDQLE-----------------
MMAR_1248|M.marinum_M VSRLLAKSLARLRDQLE-----------------
MUL_2640|M.ulcerans_Agy99 VSRLLAKSLARLRDQLE-----------------
MAV_4256|M.avium_104 VSRLLAKSLTRLRDQLQ-----------------
TH_0241|M.thermoresistible__bu VSRLLAKSLARLRDQLE-----------------
MSMEG_1804|M.smegmatis_MC2_155 VSRLLAKSLARLRDQLQ-----------------
MAB_2511|M.abscessus_ATCC_1997 VSRILSDTLRYLREQMA-----------------
MLBr_01022|M.leprae_Br4923 IRQIESKTMSKLRHPSRSQVLRDYLD--------
: :: : :: **.