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NTHFPDTETIHAALALAMRAPSIHNSQPWQWRVGERSVHLYADLDRHLTSTDPDSRDLLLSCGAALHHCV IAFAALGWYASVHRLPNPAEPEHLASIELRRQTPTDLDIALAAAIPRRRTDRRHYSAWPVSHSDIAMMGA RAARAGVMLRRVESLSRLQDIVAESIARHAADDGYLRELTAWSGKYASTAGVPARSAPKPEPGAPLSSRM FAGAALKQPDTGAGADEGAVVLALGTADDTRMSRLRAGEATSLILLTATAMGLATCPVTEPLEISETRDA VQAEVFGASAFPQMMLRVGWAPVNADPLPPTPRRHVADAVRWLDGSPFEPESE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3955 | - | - | 100% (334) | hypothetical protein MSMEG_3955 |
| M. smegmatis MC2 155 | MSMEG_3952 | - | 2e-43 | 38.32% (321) | hypothetical protein MSMEG_3952 |
| M. smegmatis MC2 155 | MSMEG_3943 | - | 3e-42 | 37.38% (313) | hypothetical protein MSMEG_3943 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3155 | - | 1e-121 | 62.54% (323) | hypothetical protein Mb3155 |
| M. gilvum PYR-GCK | Mflv_3848 | - | 1e-128 | 67.37% (331) | hypothetical protein Mflv_3848 |
| M. tuberculosis H37Rv | Rv3131 | - | 1e-121 | 62.54% (323) | hypothetical protein Rv3131 |
| M. leprae Br4923 | MLBr_01751 | - | 8e-06 | 24.37% (316) | hypothetical protein MLBr_01751 |
| M. abscessus ATCC 19977 | MAB_3903 | - | 4e-47 | 37.62% (319) | hypothetical protein MAB_3903 |
| M. marinum M | MMAR_3502 | - | 1e-124 | 63.58% (324) | hypothetical protein MMAR_3502 |
| M. avium 104 | MAV_2502 | - | 1e-120 | 62.35% (324) | hypothetical protein MAV_2502 |
| M. thermoresistible (build 8) | TH_0558 | - | 4e-57 | 69.86% (146) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2421 | - | 1e-115 | 58.82% (323) | hypothetical protein MUL_2421 |
| M. vanbaalenii PYR-1 | Mvan_2547 | - | 1e-122 | 62.80% (328) | hypothetical protein Mvan_2547 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3848|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2547|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3955|M.smegmatis_MC2_155 --------------------------------------------------
Mb3155|M.bovis_AF2122/97 --------------------------------------------------
Rv3131|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2421|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3502|M.marinum_M --------------------------------------------------
MAV_2502|M.avium_104 --------------------------------------------------
TH_0558|M.thermoresistible__bu --------------------------------------------------
MAB_3903|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01751|M.leprae_Br4923 MAYGCNPRGAARVSDERDVSPYARVLALDDPADAAVLQRLRADSKVDFVD
Mflv_3848|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2547|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3955|M.smegmatis_MC2_155 --------------------------------------------------
Mb3155|M.bovis_AF2122/97 --------------------------------------------------
Rv3131|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2421|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3502|M.marinum_M --------------------------------------------------
MAV_2502|M.avium_104 --------------------------------------------------
TH_0558|M.thermoresistible__bu --------------------------------------------------
MAB_3903|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01751|M.leprae_Br4923 HHERQLQELLSLLPTPDPQLIAEPCRWVYYPWRHVVVSMLGPRGFRAVRL
Mflv_3848|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2547|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3955|M.smegmatis_MC2_155 --------------------------------------------------
Mb3155|M.bovis_AF2122/97 --------------------------------------------------
Rv3131|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2421|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3502|M.marinum_M --------------------------------------------------
MAV_2502|M.avium_104 --------------------------------------------------
TH_0558|M.thermoresistible__bu --------------------------------------------------
MAB_3903|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01751|M.leprae_Br4923 DRNRNEITAEEQVALGRLHIGVAGLSVGHVIAHTLAAQGLCGQLRLADFD
Mflv_3848|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2547|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3955|M.smegmatis_MC2_155 --------------------------------------------------
Mb3155|M.bovis_AF2122/97 --------------------------------------------------
Rv3131|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2421|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3502|M.marinum_M --------------------------------------------------
MAV_2502|M.avium_104 --------------------------------------------------
TH_0558|M.thermoresistible__bu --------------------------------------------------
MAB_3903|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01751|M.leprae_Br4923 RLELSNLNRVPATVFDLGLNKAEVAARRIAELDPYLTVRVFDNGLTFDTV
Mflv_3848|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2547|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3955|M.smegmatis_MC2_155 --------------------------------------------------
Mb3155|M.bovis_AF2122/97 --------------------------------------------------
Rv3131|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2421|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3502|M.marinum_M --------------------------------------------------
MAV_2502|M.avium_104 --------------------------------------------------
TH_0558|M.thermoresistible__bu --------------------------------------------------
MAB_3903|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01751|M.leprae_Br4923 DQFLEGLDVVVEQCDSLDIKALLREGARSHGIPVLMATSDRGLIDVERFD
Mflv_3848|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2547|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3955|M.smegmatis_MC2_155 --------------------------------------------------
Mb3155|M.bovis_AF2122/97 --------------------------------------------------
Rv3131|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2421|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3502|M.marinum_M --------------------------------------------------
MAV_2502|M.avium_104 --------------------------------------------------
TH_0558|M.thermoresistible__bu --------------------------------------------------
MAB_3903|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01751|M.leprae_Br4923 LEPRRSILHGLLGELDIRLLPEMSNREKIPYILRFLEAERLSPRTATTLV
Mflv_3848|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2547|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3955|M.smegmatis_MC2_155 --------------------------------------------------
Mb3155|M.bovis_AF2122/97 --------------------------------------------------
Rv3131|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2421|M.ulcerans_Agy99 ----------------------------------------MTYDSDGTAC
MMAR_3502|M.marinum_M --------------------------------------------------
MAV_2502|M.avium_104 --------------------------------------------------
TH_0558|M.thermoresistible__bu --------------------------------------------------
MAB_3903|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01751|M.leprae_Br4923 EIDRSLSTWPQLAGDVALGATAVAEAVRRIGLGEELRSGRARIDVASALN
Mflv_3848|M.gilvum_PYR-GCK ------MNAHFPDAETLRSALSLA----------NRAPSVHNSQPWQWRV
Mvan_2547|M.vanbaalenii_PYR-1 ------MTTNFPDSVTLRSALSLA----------NRAPSVHNSQPWQWRV
MSMEG_3955|M.smegmatis_MC2_155 ------MNTHFPDTETIHAALALA----------MRAPSIHNSQPWQWRV
Mb3155|M.bovis_AF2122/97 ------MNTHFPDAETVRTVLTLA----------VRAPSIHNTQPWRWRV
Rv3131|M.tuberculosis_H37Rv ------MNTHFPDAETVRTVLTLA----------VRAPSIHNTQPWRWRV
MUL_2421|M.ulcerans_Agy99 LTGKAAMNAQFPDVGTLRTVLTLA----------TRAPSIHNTQPWRWQV
MMAR_3502|M.marinum_M ------MNAHFPDAGTVRTVLTLA----------SRAPSVHNTQPWRWQV
MAV_2502|M.avium_104 ------MTNRFPDEGTIRTVLALA----------SRAPSVHNTQPWRWLV
TH_0558|M.thermoresistible__bu --------------------LALA----------VRAPSVHNSQPWRWRV
MAB_3903|M.abscessus_ATCC_1997 ------MPKTMVHIDVIQTAIQLA----------CRAPSLHNTQPWRWIV
MLBr_01751|M.leprae_Br4923 QLTEPDMARHRPANPTQCSELALSGIEGVIATAAIRAPSGGNLQPWHIDA
: *: **** * ***: .
Mflv_3848|M.gilvum_PYR-GCK GH----ESVHLYANPDLLLPHTDPDARDLMLSCGAALHHCVVALAALGWQ
Mvan_2547|M.vanbaalenii_PYR-1 GD----HSLHLFANPDLLLPHIDPDARDFMLSCGTALNHCVVALAALGWQ
MSMEG_3955|M.smegmatis_MC2_155 GE----RSVHLYADLDRHLTSTDPDSRDLLLSCGAALHHCVIAFAALGWY
Mb3155|M.bovis_AF2122/97 CP----TSLELFSRPDMQLRSTDPDGRELILSCGVALHHCVVALASLGWQ
Rv3131|M.tuberculosis_H37Rv CP----TSLELFSRPDMQLRSTDPDGRELILSCGVALHHCVVALASLGWQ
MUL_2421|M.ulcerans_Agy99 TS----RSLELFPEPDMQLHSTDPDGRDLIISCGVALHHCVVALASMGWQ
MMAR_3502|M.marinum_M GA----TTLHLYADTSLQLPNTDPEGRDLISSCGAALNHCVIALAAVGWH
MAV_2502|M.avium_104 GQ----ESLHLYADGGRQLPNTDPDGRDLILSCGAALHHCVVGFAAVGWQ
TH_0558|M.thermoresistible__bu GT----ESLHLWADPEHHLPSIDPDRRDLLVSCGAALNHCIIALAALGWQ
MAB_3903|M.abscessus_ATCC_1997 DLGASAGDLHLYLDRTRCVTRTDGAGREAIISCGAALDHFRVAMASAGWM
MLBr_01751|M.leprae_Br4923 GP-----DALVIRIAPEHTDSLDVGFRGSAVAVGAALFNARVAAAAHGVL
: * * : *.** : :. *: *
Mflv_3848|M.gilvum_PYR-GCK AKIHRFPNPAEPDHLAALELRRYPAADL-DVTLAAAIPRRRTDRRYYSSW
Mvan_2547|M.vanbaalenii_PYR-1 SKVHRFPNPADPNHVAAIQVHRYPAAEL-DITLAAAIPRRRTDRRHYSPW
MSMEG_3955|M.smegmatis_MC2_155 ASVHRLPNPAEPEHLASIELRRQTPTDL-DIALAAAIPRRRTDRRHYSAW
Mb3155|M.bovis_AF2122/97 AKVNRFPDPKDRCHLATIGVQPLVPDQA-DVALAAAIPRRRTDRRAYSCW
Rv3131|M.tuberculosis_H37Rv AKVNRFPDPKDRCHLATIGVQPLVPDQA-DVALAAAIPRRRTDRRAYSCW
MUL_2421|M.ulcerans_Agy99 ATVTRIPDPDNSRHLASLELQAKPPDQG-DIALAAAIPRRRTDWRAYSSW
MMAR_3502|M.marinum_M AKVARLPNPADPTHLAALEVSRHTPDQL-NITLAAAIPRRRTDRRHYSFW
MAV_2502|M.avium_104 ARVTRLPNPADPDHLAAIELSGGTADPV-DIALAAAIPRRRTDRRHYSSW
TH_0558|M.thermoresistible__bu AKVHRFPNPAEPLHLASLELSVHKPTEA-EVSLAAAIPRRRTDRRLYSNW
MAB_3903|M.abscessus_ATCC_1997 TRIERIPDPDNPDHLAAITFSPRTVVVVGDRRRADAILQRRTDRLPFETP
MLBr_01751|M.leprae_Br4923 GPVSLAENVDGAPLRVTLSLGDGWNPDL--AAVYEPMLVRETNRNHGKPT
: : .:: . .: *.*: .
Mflv_3848|M.gilvum_PYR-GCK PVPQGDVALMGARAARAGVALRRVDDLAG------LKRLVSAAAFQHRTD
Mvan_2547|M.vanbaalenii_PYR-1 PVPRGDIALMGARAARAGVMLRRVDDLDA------LKRLVNEAAFQHQSD
MSMEG_3955|M.smegmatis_MC2_155 PVSHSDIAMMGARAARAGVMLRRVESLSR------LQDIVAESIARHAAD
Mb3155|M.bovis_AF2122/97 PVPGGDIALMAARAARGGVMLRQVSALDR------MKAIVAQAVLDHVTD
Rv3131|M.tuberculosis_H37Rv PVPGGDIALMAARAARGGVMLRQVSALDR------MKAIVAQAVLDHVTD
MUL_2421|M.ulcerans_Agy99 PVAAGDIAQMAARVARCDVALRQVEALDK------MREVVAQAVWDHATN
MMAR_3502|M.marinum_M PVPVSDVALMAARAARCGVSLRQVDATDK------LNAIVAKSVWDHAAD
MAV_2502|M.avium_104 PVPVGDIALMAARAARNGVTLCQVEDADK------LHEIVKQSVWDHMN-
TH_0558|M.thermoresistible__bu PVPFGDIALMGARAARAGVRLLRVEDLDH------VRSAXXX--------
MAB_3903|M.abscessus_ATCC_1997 PNWSQFARMLNTVIADRAVLLDVIDDVMRPK----LADASALSDALRIYD
MLBr_01751|M.leprae_Br4923 MVLTETIDVLHAAAVAEGARLHLLTARDDIVRAATILAAADRSRYLTPRL
: : . . * : :
Mflv_3848|M.gilvum_PYR-GCK AGYLTELAAWSGRYAATAGVPARSVP-AETAGAVSARAFAGGVLPQTPDT
Mvan_2547|M.vanbaalenii_PYR-1 QGYLAELATWSGRYASTAGVPARNVPDGDGTGPIPLRAFAGGVLPQTPNT
MSMEG_3955|M.smegmatis_MC2_155 DGYLRELTAWSGKYASTAGVPARSAPKPEPGAPLSSRMFAGAALKQPDTG
Mb3155|M.bovis_AF2122/97 EEYLRELTIWSGRYGSVAGVPARNEPPSDPSAPIPGRLFAGPGLSQPSDV
Rv3131|M.tuberculosis_H37Rv EEYLRELTIWSGRYGSVAGVPARNEPPSDPSAPIPGRLFAGPGLSQPSDV
MUL_2421|M.ulcerans_Agy99 DEYMRELTTWSGRYGAVAGVPARNTPPSDQDAPIPGRLFAGPGLAQPSGV
MMAR_3502|M.marinum_M DEYLAELNAWSGRHASASGVPARNTPVSDPAAPLPSRLFAGSTLAMPADA
MAV_2502|M.avium_104 RDYLVELAAWSGRYAAVAGVPARNTPKSDPGAKIPGRLFAGPMLAMPSGS
TH_0558|M.thermoresistible__bu ------------------GCTSRFR-------------------------
MAB_3903|M.abscessus_ATCC_1997 SAYQTELDWWTAPFTLEDGVPRSALVSAADSDRVDIGRTFPVVAERASRP
MLBr_01751|M.leprae_Br4923 HEEMISELRWPGDSFPDTGIDVRSLEMDWHQLAAFDVLRRTDVMELLAQW
*
Mflv_3848|M.gilvum_PYR-GCK AA-----------DQDNAVVLALGTAGDDRLSWLRAGEATSVVLLTATAL
Mvan_2547|M.vanbaalenii_PYR-1 EP-----------ADDNAAVLALGTVEDDRLSWLRAGEATSIVLLTATAL
MSMEG_3955|M.smegmatis_MC2_155 AG-----------ADEGAVVLALGTADDTRMSRLRAGEATSLILLTATAM
Mb3155|M.bovis_AF2122/97 LP-----------ADDGAAILALGTETDDRLARLRAGEAASIVLLTATAM
Rv3131|M.tuberculosis_H37Rv LP-----------ADDGAAILALGTETDDRLARLRAGEAASIVLLTATAM
MUL_2421|M.ulcerans_Agy99 SP-----------AADSAVILALGTEEDDRASRLRAGEATSAVLLTATAM
MMAR_3502|M.marinum_M AP-----------ADDNAVMLALGTRTDDRLAQLRAGEATSVVLLTATAM
MAV_2502|M.avium_104 SA-----------AEDNSVLLALGTRGDDRLARLRAGEATSMVLLTATSM
TH_0558|M.thermoresistible__bu -----------------------------RPTRRRRTRAVSHG-------
MAB_3903|M.abscessus_ATCC_1997 GL-----------QEDQAKVLALSTARDTPKNLLRCGELLSEVLLEATLA
MLBr_01751|M.leprae_Br4923 NVGAALGQDTHDRVVASSALAVISVPGHALADYARGGSAVEAIWVAAQRY
* .
Mflv_3848|M.gilvum_PYR-GCK GLASCPITEPLEIAETR---EAVRRDVFGADGYPQMLLRVGWAPVNADPL
Mvan_2547|M.vanbaalenii_PYR-1 GLACCPITEPLEIADTR---EAVRRDVFGTDGHPQMLLRVGWAPVNADPL
MSMEG_3955|M.smegmatis_MC2_155 GLATCPVTEPLEISETR---DAVQAEVFGASAFPQMMLRVGWAPVNADPL
Mb3155|M.bovis_AF2122/97 GLACCPITEPLEIAKTR---DAVRAEVFGAGGYPQMLLRVGWAPINADPL
Rv3131|M.tuberculosis_H37Rv GLACCPITEPLEIAKTR---DAVRAEVFGAGGYPQMLLRVGWAPINADPL
MUL_2421|M.ulcerans_Agy99 GLASCPITEPLEVHKTR---QAIRKDVFGGSAYPQMLLRVGWAPINADPL
MMAR_3502|M.marinum_M GLASCPVTEPLEIAETR---ESVRTDVFGNNDYPQMLLRVGWAPINADPL
MAV_2502|M.avium_104 GLASCPVTEPLEVADTR---EAVRTEIFGGSNYPQMLLRIGWPPINADPL
TH_0558|M.thermoresistible__bu -----------EAGDNR---EKNHSPWWASN-----LAVRGWLGN----L
MAB_3903|M.abscessus_ATCC_1997 GMATCTITHMLELTASR---EVVG--AAIGRSHPQALIRVGLAPTFGRIP
MLBr_01751|M.leprae_Br4923 GFAVQPISPVFLYAHSVDELHALSAQFADELGQLGKDFRSLARIPADNSL
. .
Mflv_3848|M.gilvum_PYR-GCK PSTPRRNLSEVVVRLDDSSAE-------
Mvan_2547|M.vanbaalenii_PYR-1 PATPRRDVTEVIAHLDGSPIA-------
MSMEG_3955|M.smegmatis_MC2_155 PPTPRRHVADAVRWLDGSPFEPESE---
Mb3155|M.bovis_AF2122/97 PPTPRRELSQVVEWPEELLRQRC-----
Rv3131|M.tuberculosis_H37Rv PPTPRRELSQVVEWPEELLRQRC-----
MUL_2421|M.ulcerans_Agy99 PATPRRNLSRVVEWPEQLLDERG-----
MMAR_3502|M.marinum_M PSTPRRPLAEIVEWMSDREQCGTE----
MAV_2502|M.avium_104 PATPRRELCDFVEWMTDREPGIAE----
TH_0558|M.thermoresistible__bu VFTRRG-----VEQLGSSLGS-------
MAB_3903|M.abscessus_ATCC_1997 PPTPRRSLADVFEIRS------------
MLBr_01751|M.leprae_Br4923 VLVLRLTVAGPASVRSRRSFERIRLLSG
. *