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STLAQQHDCLLLDLDGTVFRGHEPTPGAVDTLAGVDTRILFVTNNASRSAGQVSDHLCELGFSAAPPDVV TSAQSAARLLAEQLPSGAKVLVVGTDSLADEVSNVGLAPVREYSEGPAAVVQGHNPETAWQILAEAALAI RSGALWVAANVDRTLPSERGLLPGNGSMVAALRAATDSEPQVAGKPAPALMADALSRGDFQTPLVVGDRL DTDIAGANAARLPSLMVLCGVNNAADAIWAVEDERPGFLAEDLRALTAHAADVLRIAPDPAWRVDVTEKA VTVSSTGTTASDPLAPVRAIAAAVWESGIGRRPIVGADDAARQAVERWSLASAAID*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3511 | - | - | 100% (337) | HAD family hydrolase |
| M. gilvum PYR-GCK | Mflv_0147 | - | 7e-14 | 24.46% (233) | Fis family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1718 | - | 1e-108 | 61.00% (341) | phosphatase |
| M. tuberculosis H37Rv | Rv1692 | - | 1e-108 | 61.00% (341) | phosphatase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2357 | - | 1e-107 | 63.75% (331) | HAD-superfamily hydrolase |
| M. marinum M | MMAR_2497 | - | 1e-110 | 62.76% (333) | phosphatase |
| M. avium 104 | MAV_3079 | - | 1e-113 | 64.07% (334) | HAD-superfamily protein hydrolase, subfamily protein IIA |
| M. smegmatis MC2 155 | MSMEG_3753 | - | 1e-122 | 66.47% (343) | hydrolase |
| M. thermoresistible (build 8) | TH_1551 | - | 1e-121 | 65.12% (344) | PROBABLE PHOSPHATASE |
| M. ulcerans Agy99 | MUL_1681 | - | 1e-109 | 62.76% (333) | phosphatase |
| M. vanbaalenii PYR-1 | Mvan_3292 | - | 1e-147 | 78.04% (337) | HAD family hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3511|M.gilvum_PYR-GCK ---MSTLAQQHDCLLLDLDGTVFRGHEPTPGAVDTLAGVD-TRILFVTNN
Mvan_3292|M.vanbaalenii_PYR-1 ---MTTLAQQHDCLLLDLDGTVFRGHEPTPGAVDTLASVD-SRILFVTNN
MSMEG_3753|M.smegmatis_MC2_155 ---MTTLARQHDCLLLDLDGTVFRGHEATPGAVESLAGLD-ARLLYVTNN
TH_1551|M.thermoresistible__bu ---VNSVAQHHDCLLLDLDGTVFRGHEPTPGAVESLRTVA-ARTLYVTNN
Mb1718|M.bovis_AF2122/97 ---MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVR-SRKLFVTNN
Rv1692|M.tuberculosis_H37Rv ---MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVR-SRKLFVTNN
MMAR_2497|M.marinum_M ---MKNIAQEYDCLLIDLDGTVFRGSQPTEGAVESLDEVT-ARKLFVTNN
MUL_1681|M.ulcerans_Agy99 ---MKNIAQEYDCLLIDLDGTVFRGSQPTEGAVESLDEVT-ARKLFVTNN
MAV_3079|M.avium_104 MSGVKTLAQQHDCLLIDLDGTAFRGRSPTEGAVQALARLP-GRALFVTNN
MAB_2357|M.abscessus_ATCC_1997 --MPDTLATSYDCLLLDLDGTVFRGAEPTANAIESLAAASGARQLYVTNN
.:* :****:*****.* * ..* .*:::* * *:****
Mflv_3511|M.gilvum_PYR-GCK ASRSAGQVSDHLCELGFSAAPPDVVTSAQSAARLLAEQLPSGAKVLVVGT
Mvan_3292|M.vanbaalenii_PYR-1 ASRDAEQVAEHLRELGFAAAADDVVTSAQSAARLLAGQVPPGGRVLVVGT
MSMEG_3753|M.smegmatis_MC2_155 ASRAPQQVAEHLRELGFSGDADDVVTSAQSAARVLAAQLPADARVLVVGT
TH_1551|M.thermoresistible__bu ASRAPGEVAEHLRSLGFAAAAEDVVTSAQSAARLLATTLPAGAPVLVLGT
Mb1718|M.bovis_AF2122/97 ASRSADEVAAHLCELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGT
Rv1692|M.tuberculosis_H37Rv ASRSADEVAAHLCELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGT
MMAR_2497|M.marinum_M ASRSAGEVAVHLRELGFTATSEDVVTSAQSAAHLLAAALPPGSKVLVVGT
MUL_1681|M.ulcerans_Agy99 ASRSAGEVAVHLRELGFTATSEDVVTSAQSAAHLLAAALPPGSKVLVVGT
MAV_3079|M.avium_104 ASRSAGEVAAHLTELGFTATADDVATSAQSAAHLLAGQLPAGAPVLIVGT
MAB_2357|M.abscessus_ATCC_1997 ASRSAPEVADHLAALGFTAAAGDVVTSAQSAARLLAEELNRGDAVLVVGT
*** . :*: ** ***:. **.*******::** : . **::**
Mflv_3511|M.gilvum_PYR-GCK DSLADEVSNVGLAPVREYSEGPAAVVQGHNPETAWQILAEAALAIRSGAL
Mvan_3292|M.vanbaalenii_PYR-1 DALADEISGVGLEPVRRWSDRPVAVVQGHSPDTGWQHLAEAALAIRSGAL
MSMEG_3753|M.smegmatis_MC2_155 EALADEVRNVGLRPVRQFAEDPVAVVQGHNPQTGWADLAEAALAIRAGAL
TH_1551|M.thermoresistible__bu EALAEEVRAVGLEPVRQFADRPVAVVQGISQQTGWPELAEAALAIRAGAW
Mb1718|M.bovis_AF2122/97 EALANEVAAVGLRPVRRFEDRPDAVVQGLSMTTGWSDLAEAALAIRAGAL
Rv1692|M.tuberculosis_H37Rv EALANEVAAVGLRPVRRFEDRPDAVVQGLSMTTGWSDLAEAALAIRAGAL
MMAR_2497|M.marinum_M DALADEISAAGLRPVRRFEDQPDAVVQGLSLTIGWPELAEAALAIRAGAL
MUL_1681|M.ulcerans_Agy99 DALADEISAAGLRPVRRFEDQPDAVVQGLSLTIGWPELAEAALAIRAGAL
MAV_3079|M.avium_104 EALAGEIAAVGLRPVRRYDDGPVAVVQGLSMTIGWPDLAEAALAIRAGAV
MAB_2357|M.abscessus_ATCC_1997 EALAAEVAAVGLTPVRSFDEAPRAVVQGHSPDTGWTTLAEAALAIRAGAY
::** *: .** *** : : * ***** . .* *********:**
Mflv_3511|M.gilvum_PYR-GCK WVAANVDRTLPSERGLLPGNGSMVAALRAATDSEPQVAGKPAPALMADAL
Mvan_3292|M.vanbaalenii_PYR-1 WVAANVDKTLPSEHGLLPGNGSMVAALRTATDADPQVAGKPAPALMQDAL
MSMEG_3753|M.smegmatis_MC2_155 WVAANVDLTLPSERGLLPGNGSMVAALRVATGHDPQVAGKPQPTLMRDAL
TH_1551|M.thermoresistible__bu WVATNADRTLPSERGLLPGNGAMIAALRAATDREPEVAGKPQATLMLDAL
Mb1718|M.bovis_AF2122/97 WVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAGKPAPALMTEAV
Rv1692|M.tuberculosis_H37Rv WVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAGKPAPALMTEAV
MMAR_2497|M.marinum_M WVAANVDKTLPTERGLLPGNGSLVAALRTATGAQPQVAGKPGPQLMKDAV
MUL_1681|M.ulcerans_Agy99 WVAANVDKTLPTERGLLPGNGSFVAALRTATGAQPQVAGKPGPQLMKDAV
MAV_3079|M.avium_104 WVAANIDLTLPTERGLLPGNGSLVAAVAAATGATPQVAGKPAPALLRDAA
MAB_2357|M.abscessus_ATCC_1997 WVAANVDATLPTERGLLPGNGSMVAALRTATDADPVVAGKPGRALIEDAL
***:* * ***:*:*******:::**: .**. * ***** *: :*
Mflv_3511|M.gilvum_PYR-GCK SRGDFQTPLVVGDRLDTDIAGANAARLPSLMVLCGVNNAADAIWAVEDER
Mvan_3292|M.vanbaalenii_PYR-1 ARGEFDRPLVVGDRLDTDIAGANAARLPSLMVLCGVNSAEDAIWAVREQR
MSMEG_3753|M.smegmatis_MC2_155 SRGSFEAPLVVGDRLDTDIACAVSAGLPSLMVLSGVSTATDAVFAAEHER
TH_1551|M.thermoresistible__bu SRGSFERPLVVGDRLDTDIAGANNAGLPSLLVLTGVNDAADAIWAVPGER
Mb1718|M.bovis_AF2122/97 ARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPVRR
Rv1692|M.tuberculosis_H37Rv ARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPVRR
MMAR_2497|M.marinum_M GRGDFRAPLVIGDRLDTDIEGANAAGLPSLMVLTGVSSARDAVHADPVCR
MUL_1681|M.ulcerans_Agy99 GRGDFRAPLVIGDRLDTDIEGANAAGLPSLMVLTGVSSARDAVHADPVCR
MAV_3079|M.avium_104 ARGDFRAPLVIGDRLDTDIEGANAAGLPSLLVLTGVNSARDAVYAKPARR
MAB_2357|M.abscessus_ATCC_1997 ARGSFARPLVVGDRLDTDISGANGAGLPSLMVLTGVNSAIDAIWADIAHR
.**.* .**:******** * * ****:** **. * **: * *
Mflv_3511|M.gilvum_PYR-GCK PGFLAEDLRALTAHAADVLRIAPDPAWRVDVTEK-AVTVSSTG-----TT
Mvan_3292|M.vanbaalenii_PYR-1 PTFLAADLRALTADDTEALRIAPHPGWRVEVDNV-AVTLTATG-----SD
MSMEG_3753|M.smegmatis_MC2_155 PDYIAADLRSLHV-AAETLRVGPQPEWRVEVDSD-RVEVYSTG-----KV
TH_1551|M.thermoresistible__bu PDLIAADLRSLHT-PAEELRVAPHPAWRVDLNDGGTIRVTSTG-----AD
Mb1718|M.bovis_AF2122/97 PTYIGHDLRSLHQ-DSKLLAVAPQPGWQIDVGGG-AVTVCANGDVDDLEF
Rv1692|M.tuberculosis_H37Rv PTYIGHDLRSLHQ-DSKLLAVAPQPGWQIDVGGG-AVTVCANGDVDDLEF
MMAR_2497|M.marinum_M PTYIGHDLRSLRQ-DRATLAVAPQAGWRVQVDGA-AVTVSANG-----EQ
MUL_1681|M.ulcerans_Agy99 PTYIGHDLRSLRQ-DRATLAVAPQAGWRVQVDGA-AVTVSANG-----EQ
MAV_3079|M.avium_104 PTYIGHDLRALHQ-DAAALAVAPQPGWRVDVGDT-AITVSGDGRD---DG
MAB_2357|M.abscessus_ATCC_1997 PTFLGADLSALHL-PQADVRIEPKPSWQVSVSSD-EVSVTAGD------P
* :. ** :* : : *.. *::.: : : . .
Mflv_3511|M.gilvum_PYR-GCK ASDPLAPVRAIAAAVWESG------IGRRPIVGADDAARQAVERWSLASA
Mvan_3292|M.vanbaalenii_PYR-1 PGDSLAPVRAIAAAVWASG------IARRPIRGHDDTARQAVQRWSLVSD
MSMEG_3753|M.smegmatis_MC2_155 TDDPLSVVRAVAHAVWTDSDDHVYDNDGYTLVAGDDTARAALQRASLLSP
TH_1551|M.thermoresistible__bu PGDPLSVVRAVAHAVWTADLVTTGDTAGLPIIGADDAARAALHRWALSPF
Mb1718|M.bovis_AF2122/97 IDDGLSIVRAVASAVWEAR-AADLHQRPLRIEAGDERARAALQRWSLMRS
Rv1692|M.tuberculosis_H37Rv IDDGLSIVRAVASAVWEAR-AADLHQRPLRIEAGDERARAALQRWSLMRS
MMAR_2497|M.marinum_M AGDDLSIVRAVACAVWDA----QFDGRPFTVNGGDDHAWEGLHRWSLVHS
MUL_1681|M.ulcerans_Agy99 AGDDLSIVRAVACAVWDA----QFDGRPFTVNGGDDHAWERLHRWSLVHS
MAV_3079|M.avium_104 SGDGLSVVRAVASAVWGS-----PDAGTLPIRAGDDRARAALARWSLVRT
MAB_2357|M.abscessus_ATCC_1997 TGSSVSLAQAVAAAVWATG----PAPDARPIVATGDLAERAVQQLSAG--
.. :: .:*:* *** : . .: * : : :
Mflv_3511|M.gilvum_PYR-GCK AID-------
Mvan_3292|M.vanbaalenii_PYR-1 RID-------
MSMEG_3753|M.smegmatis_MC2_155 SID-------
TH_1551|M.thermoresistible__bu RID-------
Mb1718|M.bovis_AF2122/97 DHPVTSVGTQ
Rv1692|M.tuberculosis_H37Rv DHPVTSVGTQ
MMAR_2497|M.marinum_M E---------
MUL_1681|M.ulcerans_Agy99 E---------
MAV_3079|M.avium_104 D---------
MAB_2357|M.abscessus_ATCC_1997 ----------