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M. marinum M MMAR_2497 (-)

annotation: phosphatase
coordinates: 3040974 - 3041984
length: 336

VKNIAQEYDCLLIDLDGTVFRGSQPTEGAVESLDEVTARKLFVTNNASRSAGEVAVHLRELGFTATSEDV
VTSAQSAAHLLAAALPPGSKVLVVGTDALADEISAAGLRPVRRFEDQPDAVVQGLSLTIGWPELAEAALA
IRAGALWVAANVDKTLPTERGLLPGNGSLVAALRTATGAQPQVAGKPGPQLMKDAVGRGDFRAPLVIGDR
LDTDIEGANAAGLPSLMVLTGVSSARDAVHADPVCRPTYIGHDLRSLRQDRATLAVAPQAGWRVQVDGAA
VTVSANGEQAGDDLSIVRAVACAVWDAQFDGRPFTVNGGDDHAWEGLHRWSLVHSE
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2497--100% (336)phosphatase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1718-1e-13873.55% (344) phosphatase
M. gilvum PYR-GCKMflv_3511-1e-11062.76% (333) HAD family hydrolase
M. tuberculosis H37RvRv1692-1e-13873.55% (344) phosphatase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2357-1e-10262.58% (318) HAD-superfamily hydrolase
M. avium 104MAV_3079-1e-13571.89% (338) HAD-superfamily protein hydrolase, subfamily protein IIA
M. smegmatis MC2 155MSMEG_3753-1e-10962.91% (337) hydrolase
M. thermoresistible (build 8)TH_1551-1e-11262.61% (337) PROBABLE PHOSPHATASE
M. ulcerans Agy99MUL_1681-0.099.40% (336) phosphatase
M. vanbaalenii PYR-1Mvan_3292-1e-11765.57% (334) HAD family hydrolase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3511|M.gilvum_PYR-GCK          ---MSTLAQQHDCLLLDLDGTVFRGHEPTPGAVDTLAGVD-TRILFVTNN
Mvan_3292|M.vanbaalenii_PYR-1       ---MTTLAQQHDCLLLDLDGTVFRGHEPTPGAVDTLASVD-SRILFVTNN
MMAR_2497|M.marinum_M               ---MKNIAQEYDCLLIDLDGTVFRGSQPTEGAVESLDEVT-ARKLFVTNN
MUL_1681|M.ulcerans_Agy99           ---MKNIAQEYDCLLIDLDGTVFRGSQPTEGAVESLDEVT-ARKLFVTNN
Mb1718|M.bovis_AF2122/97            ---MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVR-SRKLFVTNN
Rv1692|M.tuberculosis_H37Rv         ---MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVR-SRKLFVTNN
MAV_3079|M.avium_104                MSGVKTLAQQHDCLLIDLDGTAFRGRSPTEGAVQALARLP-GRALFVTNN
MSMEG_3753|M.smegmatis_MC2_155      ---MTTLARQHDCLLLDLDGTVFRGHEATPGAVESLAGLD-ARLLYVTNN
TH_1551|M.thermoresistible__bu      ---VNSVAQHHDCLLLDLDGTVFRGHEPTPGAVESLRTVA-ARTLYVTNN
MAB_2357|M.abscessus_ATCC_1997      --MPDTLATSYDCLLLDLDGTVFRGAEPTANAIESLAAASGARQLYVTNN
                                         .:*  :****:*****.* * ..* .*:::*      * *:****

Mflv_3511|M.gilvum_PYR-GCK          ASRSAGQVSDHLCELGFSAAPPDVVTSAQSAARLLAEQLPSGAKVLVVGT
Mvan_3292|M.vanbaalenii_PYR-1       ASRDAEQVAEHLRELGFAAAADDVVTSAQSAARLLAGQVPPGGRVLVVGT
MMAR_2497|M.marinum_M               ASRSAGEVAVHLRELGFTATSEDVVTSAQSAAHLLAAALPPGSKVLVVGT
MUL_1681|M.ulcerans_Agy99           ASRSAGEVAVHLRELGFTATSEDVVTSAQSAAHLLAAALPPGSKVLVVGT
Mb1718|M.bovis_AF2122/97            ASRSADEVAAHLCELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGT
Rv1692|M.tuberculosis_H37Rv         ASRSADEVAAHLCELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGT
MAV_3079|M.avium_104                ASRSAGEVAAHLTELGFTATADDVATSAQSAAHLLAGQLPAGAPVLIVGT
MSMEG_3753|M.smegmatis_MC2_155      ASRAPQQVAEHLRELGFSGDADDVVTSAQSAARVLAAQLPADARVLVVGT
TH_1551|M.thermoresistible__bu      ASRAPGEVAEHLRSLGFAAAAEDVVTSAQSAARLLATTLPAGAPVLVLGT
MAB_2357|M.abscessus_ATCC_1997      ASRSAPEVADHLAALGFTAAAGDVVTSAQSAARLLAEELNRGDAVLVVGT
                                    *** . :*: **  ***:.   **.*******::**  :  .  **::**

Mflv_3511|M.gilvum_PYR-GCK          DSLADEVSNVGLAPVREYSEGPAAVVQGHNPETAWQILAEAALAIRSGAL
Mvan_3292|M.vanbaalenii_PYR-1       DALADEISGVGLEPVRRWSDRPVAVVQGHSPDTGWQHLAEAALAIRSGAL
MMAR_2497|M.marinum_M               DALADEISAAGLRPVRRFEDQPDAVVQGLSLTIGWPELAEAALAIRAGAL
MUL_1681|M.ulcerans_Agy99           DALADEISAAGLRPVRRFEDQPDAVVQGLSLTIGWPELAEAALAIRAGAL
Mb1718|M.bovis_AF2122/97            EALANEVAAVGLRPVRRFEDRPDAVVQGLSMTTGWSDLAEAALAIRAGAL
Rv1692|M.tuberculosis_H37Rv         EALANEVAAVGLRPVRRFEDRPDAVVQGLSMTTGWSDLAEAALAIRAGAL
MAV_3079|M.avium_104                EALAGEIAAVGLRPVRRYDDGPVAVVQGLSMTIGWPDLAEAALAIRAGAV
MSMEG_3753|M.smegmatis_MC2_155      EALADEVRNVGLRPVRQFAEDPVAVVQGHNPQTGWADLAEAALAIRAGAL
TH_1551|M.thermoresistible__bu      EALAEEVRAVGLEPVRQFADRPVAVVQGISQQTGWPELAEAALAIRAGAW
MAB_2357|M.abscessus_ATCC_1997      EALAAEVAAVGLTPVRSFDEAPRAVVQGHSPDTGWTTLAEAALAIRAGAY
                                    ::** *:  .** *** : : * ***** .   .*  *********:** 

Mflv_3511|M.gilvum_PYR-GCK          WVAANVDRTLPSERGLLPGNGSMVAALRAATDSEPQVAGKPAPALMADAL
Mvan_3292|M.vanbaalenii_PYR-1       WVAANVDKTLPSEHGLLPGNGSMVAALRTATDADPQVAGKPAPALMQDAL
MMAR_2497|M.marinum_M               WVAANVDKTLPTERGLLPGNGSLVAALRTATGAQPQVAGKPGPQLMKDAV
MUL_1681|M.ulcerans_Agy99           WVAANVDKTLPTERGLLPGNGSFVAALRTATGAQPQVAGKPGPQLMKDAV
Mb1718|M.bovis_AF2122/97            WVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAGKPAPALMTEAV
Rv1692|M.tuberculosis_H37Rv         WVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAGKPAPALMTEAV
MAV_3079|M.avium_104                WVAANIDLTLPTERGLLPGNGSLVAAVAAATGATPQVAGKPAPALLRDAA
MSMEG_3753|M.smegmatis_MC2_155      WVAANVDLTLPSERGLLPGNGSMVAALRVATGHDPQVAGKPQPTLMRDAL
TH_1551|M.thermoresistible__bu      WVATNADRTLPSERGLLPGNGAMIAALRAATDREPEVAGKPQATLMLDAL
MAB_2357|M.abscessus_ATCC_1997      WVAANVDATLPTERGLLPGNGSMVAALRTATDADPVVAGKPGRALIEDAL
                                    ***:* * ***:*:*******:::**: .**.  * *****   *: :* 

Mflv_3511|M.gilvum_PYR-GCK          SRGDFQTPLVVGDRLDTDIAGANAARLPSLMVLCGVNNAADAIWAVEDER
Mvan_3292|M.vanbaalenii_PYR-1       ARGEFDRPLVVGDRLDTDIAGANAARLPSLMVLCGVNSAEDAIWAVREQR
MMAR_2497|M.marinum_M               GRGDFRAPLVIGDRLDTDIEGANAAGLPSLMVLTGVSSARDAVHADPVCR
MUL_1681|M.ulcerans_Agy99           GRGDFRAPLVIGDRLDTDIEGANAAGLPSLMVLTGVSSARDAVHADPVCR
Mb1718|M.bovis_AF2122/97            ARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPVRR
Rv1692|M.tuberculosis_H37Rv         ARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPVRR
MAV_3079|M.avium_104                ARGDFRAPLVIGDRLDTDIEGANAAGLPSLLVLTGVNSARDAVYAKPARR
MSMEG_3753|M.smegmatis_MC2_155      SRGSFEAPLVVGDRLDTDIACAVSAGLPSLMVLSGVSTATDAVFAAEHER
TH_1551|M.thermoresistible__bu      SRGSFERPLVVGDRLDTDIAGANNAGLPSLLVLTGVNDAADAIWAVPGER
MAB_2357|M.abscessus_ATCC_1997      ARGSFARPLVVGDRLDTDISGANGAGLPSLMVLTGVNSAIDAIWADIAHR
                                    .**.*  .**:********  *  * ****:** **. * **: *    *

Mflv_3511|M.gilvum_PYR-GCK          PGFLAEDLRALTAHAADVLRIAPDPAWRVDVTEK-AVTVSSTG-----TT
Mvan_3292|M.vanbaalenii_PYR-1       PTFLAADLRALTADDTEALRIAPHPGWRVEVDNV-AVTLTATG-----SD
MMAR_2497|M.marinum_M               PTYIGHDLRSLRQ-DRATLAVAPQAGWRVQVDGA-AVTVSANG-----EQ
MUL_1681|M.ulcerans_Agy99           PTYIGHDLRSLRQ-DRATLAVAPQAGWRVQVDGA-AVTVSANG-----EQ
Mb1718|M.bovis_AF2122/97            PTYIGHDLRSLHQ-DSKLLAVAPQPGWQIDVGGG-AVTVCANGDVDDLEF
Rv1692|M.tuberculosis_H37Rv         PTYIGHDLRSLHQ-DSKLLAVAPQPGWQIDVGGG-AVTVCANGDVDDLEF
MAV_3079|M.avium_104                PTYIGHDLRALHQ-DAAALAVAPQPGWRVDVGDT-AITVSGDGRD---DG
MSMEG_3753|M.smegmatis_MC2_155      PDYIAADLRSLHV-AAETLRVGPQPEWRVEVDSD-RVEVYSTG-----KV
TH_1551|M.thermoresistible__bu      PDLIAADLRSLHT-PAEELRVAPHPAWRVDLNDGGTIRVTSTG-----AD
MAB_2357|M.abscessus_ATCC_1997      PTFLGADLSALHL-PQADVRIEPKPSWQVSVSSD-EVSVTAGD------P
                                    *  :. ** :*       : : *.. *::.:     : : . .       

Mflv_3511|M.gilvum_PYR-GCK          ASDPLAPVRAIAAAVWESG------IGRRPIVGADDAARQAVERWSLASA
Mvan_3292|M.vanbaalenii_PYR-1       PGDSLAPVRAIAAAVWASG------IARRPIRGHDDTARQAVQRWSLVSD
MMAR_2497|M.marinum_M               AGDDLSIVRAVACAVWDA----QFDGRPFTVNGGDDHAWEGLHRWSLVHS
MUL_1681|M.ulcerans_Agy99           AGDDLSIVRAVACAVWDA----QFDGRPFTVNGGDDHAWERLHRWSLVHS
Mb1718|M.bovis_AF2122/97            IDDGLSIVRAVASAVWEAR-AADLHQRPLRIEAGDERARAALQRWSLMRS
Rv1692|M.tuberculosis_H37Rv         IDDGLSIVRAVASAVWEAR-AADLHQRPLRIEAGDERARAALQRWSLMRS
MAV_3079|M.avium_104                SGDGLSVVRAVASAVWGS-----PDAGTLPIRAGDDRARAALARWSLVRT
MSMEG_3753|M.smegmatis_MC2_155      TDDPLSVVRAVAHAVWTDSDDHVYDNDGYTLVAGDDTARAALQRASLLSP
TH_1551|M.thermoresistible__bu      PGDPLSVVRAVAHAVWTADLVTTGDTAGLPIIGADDAARAALHRWALSPF
MAB_2357|M.abscessus_ATCC_1997      TGSSVSLAQAVAAAVWATG----PAPDARPIVATGDLAERAVQQLSAG--
                                     .. :: .:*:* ***              : . .: *   : : :    

Mflv_3511|M.gilvum_PYR-GCK          AID-------
Mvan_3292|M.vanbaalenii_PYR-1       RID-------
MMAR_2497|M.marinum_M               E---------
MUL_1681|M.ulcerans_Agy99           E---------
Mb1718|M.bovis_AF2122/97            DHPVTSVGTQ
Rv1692|M.tuberculosis_H37Rv         DHPVTSVGTQ
MAV_3079|M.avium_104                D---------
MSMEG_3753|M.smegmatis_MC2_155      SID-------
TH_1551|M.thermoresistible__bu      RID-------
MAB_2357|M.abscessus_ATCC_1997      ----------