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TTLARQHDCLLLDLDGTVFRGHEATPGAVESLAGLDARLLYVTNNASRAPQQVAEHLRELGFSGDADDVV TSAQSAARVLAAQLPADARVLVVGTEALADEVRNVGLRPVRQFAEDPVAVVQGHNPQTGWADLAEAALAI RAGALWVAANVDLTLPSERGLLPGNGSMVAALRVATGHDPQVAGKPQPTLMRDALSRGSFEAPLVVGDRL DTDIACAVSAGLPSLMVLSGVSTATDAVFAAEHERPDYIAADLRSLHVAAETLRVGPQPEWRVEVDSDRV EVYSTGKVTDDPLSVVRAVAHAVWTDSDDHVYDNDGYTLVAGDDTARAALQRASLLSPSID*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3753 | - | - | 100% (342) | hydrolase |
| M. smegmatis MC2 155 | MSMEG_2451 | - | 4e-30 | 34.58% (240) | HAD-superfamily protein hydrolase, subfamily protein IIA |
| M. smegmatis MC2 155 | MSMEG_0867 | - | 4e-10 | 23.71% (232) | hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1718 | - | 1e-109 | 62.35% (340) | phosphatase |
| M. gilvum PYR-GCK | Mflv_3511 | - | 1e-122 | 66.47% (343) | HAD family hydrolase |
| M. tuberculosis H37Rv | Rv1692 | - | 1e-109 | 62.35% (340) | phosphatase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2357 | - | 1e-102 | 61.38% (334) | HAD-superfamily hydrolase |
| M. marinum M | MMAR_2497 | - | 1e-109 | 62.91% (337) | phosphatase |
| M. avium 104 | MAV_3079 | - | 1e-111 | 63.13% (339) | HAD-superfamily protein hydrolase, subfamily protein IIA |
| M. thermoresistible (build 8) | TH_1551 | - | 1e-126 | 69.68% (343) | PROBABLE PHOSPHATASE |
| M. ulcerans Agy99 | MUL_1681 | - | 1e-108 | 62.91% (337) | phosphatase |
| M. vanbaalenii PYR-1 | Mvan_3292 | - | 1e-121 | 66.18% (343) | HAD family hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3753|M.smegmatis_MC2_155 ---MTTLARQHDCLLLDLDGTVFRGHEATPGAVESLAGLD-ARLLYVTNN
TH_1551|M.thermoresistible__bu ---VNSVAQHHDCLLLDLDGTVFRGHEPTPGAVESLRTVA-ARTLYVTNN
Mflv_3511|M.gilvum_PYR-GCK ---MSTLAQQHDCLLLDLDGTVFRGHEPTPGAVDTLAGVD-TRILFVTNN
Mvan_3292|M.vanbaalenii_PYR-1 ---MTTLAQQHDCLLLDLDGTVFRGHEPTPGAVDTLASVD-SRILFVTNN
MAB_2357|M.abscessus_ATCC_1997 --MPDTLATSYDCLLLDLDGTVFRGAEPTANAIESLAAASGARQLYVTNN
Mb1718|M.bovis_AF2122/97 ---MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVR-SRKLFVTNN
Rv1692|M.tuberculosis_H37Rv ---MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVR-SRKLFVTNN
MMAR_2497|M.marinum_M ---MKNIAQEYDCLLIDLDGTVFRGSQPTEGAVESLDEVT-ARKLFVTNN
MUL_1681|M.ulcerans_Agy99 ---MKNIAQEYDCLLIDLDGTVFRGSQPTEGAVESLDEVT-ARKLFVTNN
MAV_3079|M.avium_104 MSGVKTLAQQHDCLLIDLDGTAFRGRSPTEGAVQALARLP-GRALFVTNN
.:* :****:*****.* * ..* .*:::* * *:****
MSMEG_3753|M.smegmatis_MC2_155 ASRAPQQVAEHLRELGFSGDADDVVTSAQSAARVLAAQLPADARVLVVGT
TH_1551|M.thermoresistible__bu ASRAPGEVAEHLRSLGFAAAAEDVVTSAQSAARLLATTLPAGAPVLVLGT
Mflv_3511|M.gilvum_PYR-GCK ASRSAGQVSDHLCELGFSAAPPDVVTSAQSAARLLAEQLPSGAKVLVVGT
Mvan_3292|M.vanbaalenii_PYR-1 ASRDAEQVAEHLRELGFAAAADDVVTSAQSAARLLAGQVPPGGRVLVVGT
MAB_2357|M.abscessus_ATCC_1997 ASRSAPEVADHLAALGFTAAAGDVVTSAQSAARLLAEELNRGDAVLVVGT
Mb1718|M.bovis_AF2122/97 ASRSADEVAAHLCELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGT
Rv1692|M.tuberculosis_H37Rv ASRSADEVAAHLCELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGT
MMAR_2497|M.marinum_M ASRSAGEVAVHLRELGFTATSEDVVTSAQSAAHLLAAALPPGSKVLVVGT
MUL_1681|M.ulcerans_Agy99 ASRSAGEVAVHLRELGFTATSEDVVTSAQSAAHLLAAALPPGSKVLVVGT
MAV_3079|M.avium_104 ASRSAGEVAAHLTELGFTATADDVATSAQSAAHLLAGQLPAGAPVLIVGT
*** . :*: ** ***:. **.*******::** : . **::**
MSMEG_3753|M.smegmatis_MC2_155 EALADEVRNVGLRPVRQFAEDPVAVVQGHNPQTGWADLAEAALAIRAGAL
TH_1551|M.thermoresistible__bu EALAEEVRAVGLEPVRQFADRPVAVVQGISQQTGWPELAEAALAIRAGAW
Mflv_3511|M.gilvum_PYR-GCK DSLADEVSNVGLAPVREYSEGPAAVVQGHNPETAWQILAEAALAIRSGAL
Mvan_3292|M.vanbaalenii_PYR-1 DALADEISGVGLEPVRRWSDRPVAVVQGHSPDTGWQHLAEAALAIRSGAL
MAB_2357|M.abscessus_ATCC_1997 EALAAEVAAVGLTPVRSFDEAPRAVVQGHSPDTGWTTLAEAALAIRAGAY
Mb1718|M.bovis_AF2122/97 EALANEVAAVGLRPVRRFEDRPDAVVQGLSMTTGWSDLAEAALAIRAGAL
Rv1692|M.tuberculosis_H37Rv EALANEVAAVGLRPVRRFEDRPDAVVQGLSMTTGWSDLAEAALAIRAGAL
MMAR_2497|M.marinum_M DALADEISAAGLRPVRRFEDQPDAVVQGLSLTIGWPELAEAALAIRAGAL
MUL_1681|M.ulcerans_Agy99 DALADEISAAGLRPVRRFEDQPDAVVQGLSLTIGWPELAEAALAIRAGAL
MAV_3079|M.avium_104 EALAGEIAAVGLRPVRRYDDGPVAVVQGLSMTIGWPDLAEAALAIRAGAV
::** *: .** *** : : * ***** . .* *********:**
MSMEG_3753|M.smegmatis_MC2_155 WVAANVDLTLPSERGLLPGNGSMVAALRVATGHDPQVAGKPQPTLMRDAL
TH_1551|M.thermoresistible__bu WVATNADRTLPSERGLLPGNGAMIAALRAATDREPEVAGKPQATLMLDAL
Mflv_3511|M.gilvum_PYR-GCK WVAANVDRTLPSERGLLPGNGSMVAALRAATDSEPQVAGKPAPALMADAL
Mvan_3292|M.vanbaalenii_PYR-1 WVAANVDKTLPSEHGLLPGNGSMVAALRTATDADPQVAGKPAPALMQDAL
MAB_2357|M.abscessus_ATCC_1997 WVAANVDATLPTERGLLPGNGSMVAALRTATDADPVVAGKPGRALIEDAL
Mb1718|M.bovis_AF2122/97 WVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAGKPAPALMTEAV
Rv1692|M.tuberculosis_H37Rv WVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAGKPAPALMTEAV
MMAR_2497|M.marinum_M WVAANVDKTLPTERGLLPGNGSLVAALRTATGAQPQVAGKPGPQLMKDAV
MUL_1681|M.ulcerans_Agy99 WVAANVDKTLPTERGLLPGNGSFVAALRTATGAQPQVAGKPGPQLMKDAV
MAV_3079|M.avium_104 WVAANIDLTLPTERGLLPGNGSLVAAVAAATGATPQVAGKPAPALLRDAA
***:* * ***:*:*******:::**: .**. * ***** *: :*
MSMEG_3753|M.smegmatis_MC2_155 SRGSFEAPLVVGDRLDTDIACAVSAGLPSLMVLSGVSTATDAVFAAEHER
TH_1551|M.thermoresistible__bu SRGSFERPLVVGDRLDTDIAGANNAGLPSLLVLTGVNDAADAIWAVPGER
Mflv_3511|M.gilvum_PYR-GCK SRGDFQTPLVVGDRLDTDIAGANAARLPSLMVLCGVNNAADAIWAVEDER
Mvan_3292|M.vanbaalenii_PYR-1 ARGEFDRPLVVGDRLDTDIAGANAARLPSLMVLCGVNSAEDAIWAVREQR
MAB_2357|M.abscessus_ATCC_1997 ARGSFARPLVVGDRLDTDISGANGAGLPSLMVLTGVNSAIDAIWADIAHR
Mb1718|M.bovis_AF2122/97 ARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPVRR
Rv1692|M.tuberculosis_H37Rv ARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPVRR
MMAR_2497|M.marinum_M GRGDFRAPLVIGDRLDTDIEGANAAGLPSLMVLTGVSSARDAVHADPVCR
MUL_1681|M.ulcerans_Agy99 GRGDFRAPLVIGDRLDTDIEGANAAGLPSLMVLTGVSSARDAVHADPVCR
MAV_3079|M.avium_104 ARGDFRAPLVIGDRLDTDIEGANAAGLPSLLVLTGVNSARDAVYAKPARR
.**.* .**:******** * * ****:** **. * **: * *
MSMEG_3753|M.smegmatis_MC2_155 PDYIAADLRSLHV-AAETLRVGPQPEWRVEVDSD-RVEVYSTGKV-----
TH_1551|M.thermoresistible__bu PDLIAADLRSLHT-PAEELRVAPHPAWRVDLNDGGTIRVTSTGAD-----
Mflv_3511|M.gilvum_PYR-GCK PGFLAEDLRALTAHAADVLRIAPDPAWRVDVTEK-AVTVSSTGTT-----
Mvan_3292|M.vanbaalenii_PYR-1 PTFLAADLRALTADDTEALRIAPHPGWRVEVDNV-AVTLTATGSD-----
MAB_2357|M.abscessus_ATCC_1997 PTFLGADLSALHLPQAD-VRIEPKPSWQVSVSSD-EVSVTA-GDP-----
Mb1718|M.bovis_AF2122/97 PTYIGHDLRSLHQ-DSKLLAVAPQPGWQIDVGGG-AVTVCANGDVDDLEF
Rv1692|M.tuberculosis_H37Rv PTYIGHDLRSLHQ-DSKLLAVAPQPGWQIDVGGG-AVTVCANGDVDDLEF
MMAR_2497|M.marinum_M PTYIGHDLRSLRQ-DRATLAVAPQAGWRVQVDGA-AVTVSANG-----EQ
MUL_1681|M.ulcerans_Agy99 PTYIGHDLRSLRQ-DRATLAVAPQAGWRVQVDGA-AVTVSANG-----EQ
MAV_3079|M.avium_104 PTYIGHDLRALHQ-DAAALAVAPQPGWRVDVGDT-AITVSGDGRD---DG
* :. ** :* : : *.. *::.: : : . *
MSMEG_3753|M.smegmatis_MC2_155 TDDPLSVVRAVAHAVWTDSDDHVYDNDGYTLVAGDDTARAALQRASLLSP
TH_1551|M.thermoresistible__bu PGDPLSVVRAVAHAVWTADLVTTGDTAGLPIIGADDAARAALHRWALSPF
Mflv_3511|M.gilvum_PYR-GCK ASDPLAPVRAIAAAVWESGIG------RRPIVGADDAARQAVERWSLASA
Mvan_3292|M.vanbaalenii_PYR-1 PGDSLAPVRAIAAAVWASGIA------RRPIRGHDDTARQAVQRWSLVSD
MAB_2357|M.abscessus_ATCC_1997 TGSSVSLAQAVAAAVWATGPAPD----ARPIVATGDLAERAVQQLSAG--
Mb1718|M.bovis_AF2122/97 IDDGLSIVRAVASAVWEARAA-DLHQRPLRIEAGDERARAALQRWSLMRS
Rv1692|M.tuberculosis_H37Rv IDDGLSIVRAVASAVWEARAA-DLHQRPLRIEAGDERARAALQRWSLMRS
MMAR_2497|M.marinum_M AGDDLSIVRAVACAVWDA----QFDGRPFTVNGGDDHAWEGLHRWSLVHS
MUL_1681|M.ulcerans_Agy99 AGDDLSIVRAVACAVWDA----QFDGRPFTVNGGDDHAWERLHRWSLVHS
MAV_3079|M.avium_104 SGDGLSVVRAVASAVWGS-----PDAGTLPIRAGDDRARAALARWSLVRT
.. :: .:*:* *** : . .: * : : :
MSMEG_3753|M.smegmatis_MC2_155 SID-------
TH_1551|M.thermoresistible__bu RID-------
Mflv_3511|M.gilvum_PYR-GCK AID-------
Mvan_3292|M.vanbaalenii_PYR-1 RID-------
MAB_2357|M.abscessus_ATCC_1997 ----------
Mb1718|M.bovis_AF2122/97 DHPVTSVGTQ
Rv1692|M.tuberculosis_H37Rv DHPVTSVGTQ
MMAR_2497|M.marinum_M E---------
MUL_1681|M.ulcerans_Agy99 E---------
MAV_3079|M.avium_104 D---------