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SSPRAGDRPKATPDWLIGRDRRSEGAERIYVAAADLMARRGYDGFGIDALAAAVHCSPATIYRHVGGKSA IRDVVLERQAEHVLDSVRQAIAGLEGSERIVTATLVALQRMRAAPLAEVMRSMPGPPGTGWLIDSPVVAR LAAEMVGTADADPLAAQWLIRVFLALWYWPMHDEEAEKAAVLRFLGPPYAGAPDDP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3474 | - | - | 100% (197) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2228 | - | 1e-14 | 29.32% (191) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1947 | - | 4e-09 | 25.29% (174) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1805c | - | 7e-44 | 48.04% (179) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv1776c | - | 7e-44 | 48.04% (179) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00815 | - | 1e-06 | 29.63% (81) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1938c | - | 1e-27 | 38.86% (175) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2651 | - | 2e-45 | 47.49% (179) | transcriptional regulatory protein |
| M. avium 104 | MAV_0009 | - | 6e-63 | 63.69% (179) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0676 | - | 3e-44 | 50.57% (176) | putative transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0937 | - | 4e-47 | 50.28% (179) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_3128 | - | 1e-45 | 48.04% (179) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_3780 | - | 4e-47 | 54.07% (172) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3474|M.gilvum_PYR-GCK --------MSSPRAGDRPKATPDWLIGRDRRSEGAER------IYVAAAD
MAV_0009|M.avium_104 ------------------MARDDWLVGRDRRSAAAER------IYAAAAD
Mvan_3780|M.vanbaalenii_PYR-1 -------------------MRDDWLVG-DRRAEAADR------IFSAATD
MSMEG_0676|M.smegmatis_MC2_155 --------------------MADWLLGGDRRTAAAER------IYAAATE
TH_0937|M.thermoresistible__bu ------------------VARTDWLVG-DRHDAAAER------IYAAATE
Mb1805c|M.bovis_AF2122/97 ------------------MPGNDWIVGGNRRTIAAER------IYAAATD
Rv1776c|M.tuberculosis_H37Rv ------------------MPGNDWIVGGNRRTIAAER------IYAAATD
MMAR_2651|M.marinum_M ------------------MPNDDWLVGGDRRRAAADR------IYDAATD
MUL_3128|M.ulcerans_Agy99 ------------------MPNDDWLVGGDRRRAAADR------IYDAATD
MAB_1938c|M.abscessus_ATCC_199 -----------------MSPYADWLHGSDRHTIAADR------IVSVAAK
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
* : ::: .* : .*:.
Mflv_3474|M.gilvum_PYR-GCK LMARRGYDGFGIDALAAAVHCSPATIYRHVGGKSAIRDVVLERQAEHVLD
MAV_0009|M.avium_104 LIARRGYDGFTIEALAARVHCSPATIYRHAGGKATIRDAVVGIQAARIVD
Mvan_3780|M.vanbaalenii_PYR-1 LIVRDGLDGFDMAALQAAVHCSRATIYRHVGGKAQIREAVLLRQAERIIA
MSMEG_0676|M.smegmatis_MC2_155 LVLRDGLDAFDIDTLAARVHCSRATVYRYAGGKAQIRDAVLLRLAASIVD
TH_0937|M.thermoresistible__bu LVLRRGLDALDVDTLAARVHCSRATVYRYTGGKAKIRDVVLTRLAAGIVE
Mb1805c|M.bovis_AF2122/97 LITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIRDVVLTRAAARIAD
Rv1776c|M.tuberculosis_H37Rv LITRYGLNALDIDKLAREVHCSRATIYRRAGGKAQIRDVVLTRAAARIAD
MMAR_2651|M.marinum_M LIAHEGINQLDIDRLATLVHCSRATVYRYVGGKNDIRNVVVKRAAARIAD
MUL_3128|M.ulcerans_Agy99 LIAHEGINQLDIDRLATLVHCSRATVYRYVGGKNDIRNVVVKRAAARIAD
MAB_1938c|M.abscessus_ATCC_199 QIARHGLDRLNLDAVAREAGCSRATVYRHVGGKTAIVDAVLARNIAKVTA
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
. * . : : . * ..:*: ..* : .*: :
Mflv_3474|M.gilvum_PYR-GCK SVRQAIAGLEG-SERIVTATLVALQRMRAAPLAEVMRS------MPGPPG
MAV_0009|M.avium_104 TTREAIKDLRG-PERVVTATIMALERLRSDPLAQLMRS------IHAAPV
Mvan_3780|M.vanbaalenii_PYR-1 TVRSAVVGLSG-AERTVTAVVVALERIRADPIGQTLLS------AMRKDE
MSMEG_0676|M.smegmatis_MC2_155 SVRQAVGHLSG-RERVVRAVTVALEHIRSDPIRQMMVG------LGAGRD
TH_0937|M.thermoresistible__bu TVRRAVDGLHG-QDRIVTAITVALEQIRSAPLRRVMLT------ADNSPD
Mb1805c|M.bovis_AF2122/97 GVRSDVETLRG-RERVVAAILLSLQRIRSDPLGKLMFGSI----HGGAGE
Rv1776c|M.tuberculosis_H37Rv GVRSDVETLRG-RERVVAAILLSLQRIRSDPLGKLMFGSI----HGGAGE
MMAR_2651|M.marinum_M SVRSAVENLSG-RERVVAAIILSVQRIRADPLGQLMISSI----HGGTQE
MUL_3128|M.ulcerans_Agy99 SVRSAVENLSG-RERVVAAIILSVQRIRADPLGQLMISSI----HGGTQE
MAB_1938c|M.abscessus_ATCC_199 DIQRAVQSADA-RRRAVVAITASLTAIRHDPVISTMIAT-----MSPTSL
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRVAA
: : * * . :. :
Mflv_3474|M.gilvum_PYR-GCK TGWLIDSPVVARLAAEMVGTADADPLAAQWLIR------VFLALWYWPMH
MAV_0009|M.avium_104 SDWVINSPTVTALAAEMLGPGHDNPLAAQWLIR------VFLALWGWPLK
Mvan_3780|M.vanbaalenii_PYR-1 LTWIGRSAVPPALAAELTGIDDDDPQAAQWIVR------VVLALLFWPVE
MSMEG_0676|M.smegmatis_MC2_155 LSELPASPVLADLAAELTGVTD-DPQAAQWIVR------VVMSLAVWPIG
TH_0937|M.thermoresistible__bu VGELHESPALSRLAAELTGITD-DPEAARWIVR------VVISMAYWPMA
Mb1805c|M.bovis_AF2122/97 LAWLTESPLLADFATELTGIAGGDPQGAKWVVR------VVLSLMYWPAE
Rv1776c|M.tuberculosis_H37Rv LAWLTESPLLADFATELTGIAGGDPQGAKWVVR------VVLSLMYWPAE
MMAR_2651|M.marinum_M VAWLADSPLLAGVASDLTGLAGGDPHAAKWVVR------IVLSLMYWPAE
MUL_3128|M.ulcerans_Agy99 VAWLADSPLLAGVASDLTGLAGGDPHAARWVVR------VVLSLMYWPAE
MAB_1938c|M.abscessus_ATCC_199 GSYLNASSEIPRSASAFTGLAD--ETAAQWISR------VVMALLFWPTS
MLBr_00815|M.leprae_Br4923 QVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWLDTN
: .. : : . *: : : :
Mflv_3474|M.gilvum_PYR-GCK DEEAEKAAVLRFLGPPY-AGAPDDP-------------------------
MAV_0009|M.avium_104 DPAAERALVHRFLGASYRPGGERDSICGA---------------------
Mvan_3780|M.vanbaalenii_PYR-1 DPAAEREMLQRFLIQRP---------------------------------
MSMEG_0676|M.smegmatis_MC2_155 DAAAEAGLVERFVAPAFE--------------------------------
TH_0937|M.thermoresistible__bu DPRLEEQTIRRFVAPAFG--------------------------------
Mb1805c|M.bovis_AF2122/97 NDEAERRLVEKYVAPAFAEQS-----------------------------
Rv1776c|M.tuberculosis_H37Rv NDEAERRLVEKYVAPAFAEQS-----------------------------
MMAR_2651|M.marinum_M SEDVERLMVEKFVAPVFAE-------------------------------
MUL_3128|M.ulcerans_Agy99 SEDVERLMVEKFVAPVFAE-------------------------------
MAB_1938c|M.abscessus_ATCC_199 DPAQESEMIERFVYPVLKDATASRVSASATSESTISPARTATFDSSEDDS
MLBr_00815|M.leprae_Br4923 RPISKSDAVEGTVQFAWGGLSHVPLTRL----------------------
: : :
Mflv_3474|M.gilvum_PYR-GCK -
MAV_0009|M.avium_104 -
Mvan_3780|M.vanbaalenii_PYR-1 -
MSMEG_0676|M.smegmatis_MC2_155 -
TH_0937|M.thermoresistible__bu -
Mb1805c|M.bovis_AF2122/97 -
Rv1776c|M.tuberculosis_H37Rv -
MMAR_2651|M.marinum_M -
MUL_3128|M.ulcerans_Agy99 -
MAB_1938c|M.abscessus_ATCC_199 P
MLBr_00815|M.leprae_Br4923 -