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GLYDFVVDRWSVLWFLAYQHISLVGQALILATAIALILGVLIYNSPLRVAAGNAVTAVGLTIPSYALLGV LVGIVGLGVLPSVIMPTFFGVFPILRNVVVGLTGVDKGLVESARGMGMSRLTTLVRLELPLAWPVIMTGV RVSAQMLMGIAAIVAFALGPGLGGYIFSGISRMGGANATNSIVAATIGILILAVILDTVLNVIARLTTPR EIRA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0034 | - | - | 100% (215) | ABC transporter permease |
| M. ulcerans Agy99 | MUL_0032 | - | 1e-19 | 40.68% (118) | hypothetical protein MUL_0032 |
| M. ulcerans Agy99 | MUL_4375 | proW | 9e-19 | 28.57% (210) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3783c | proW | 3e-20 | 29.35% (201) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. gilvum PYR-GCK | Mflv_3108 | - | 1e-51 | 46.23% (212) | binding-protein-dependent transport systems inner membrane |
| M. tuberculosis H37Rv | Rv3757c | proW | 4e-20 | 29.35% (201) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1225 | - | 9e-92 | 78.97% (214) | ABC transporter permease |
| M. marinum M | MMAR_0035 | - | 1e-112 | 97.67% (215) | ABC transporter permease |
| M. avium 104 | MAV_0320 | - | 3e-17 | 28.79% (198) | ABC transporter, permease protein |
| M. smegmatis MC2 155 | MSMEG_2927 | - | 1e-90 | 77.10% (214) | ABC transporter, permease protein OpuCB |
| M. thermoresistible (build 8) | TH_0698 | - | 2e-86 | 73.83% (214) | ABC transporter, permease protein OpuCB |
| M. vanbaalenii PYR-1 | Mvan_5599 | - | 2e-19 | 27.88% (208) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3783c|M.bovis_AF2122/97 -----------MHYLMTHPG---AAWALTVVHLRLSLLPVLIGLMSAVPL
Rv3757c|M.tuberculosis_H37Rv -----------MHYLMTHPG---AAWALTVVHLRLSLLPVLIGLMSAVPL
Mvan_5599|M.vanbaalenii_PYR-1 -----------MRYLVTHLD---ALWTLSLIHLRLSLIPILLGLLIAVPL
MUL_0034|M.ulcerans_Agy99 -------MG-LYDFVVDRWS---VLWFLAYQHISLVGQALILATAIALIL
MMAR_0035|M.marinum_M MEAATEFMG-LYDFVVDRWS---VLWFLAYQHISLVGQTLILATAIALIL
MAB_1225|M.abscessus_ATCC_1997 -------MG-FVEFVKDRWA---VLSFLAYQHMSLVLQTLVVAAMCAVFL
MSMEG_2927|M.smegmatis_MC2_155 -------MG-FVEFVQDRWA---VLSFLAYQHMSFVVQTLLIATAAALVV
TH_0698|M.thermoresistible__bu -------MD-FIEFVRERWS---VLSFLAYQHMSLVVQTLLLSTLLAVAV
Mflv_3108|M.gilvum_PYR-GCK -------MNSLWDYVSTHYQ---QLAFDSYQHVSAVVQSVLLATVIGVAI
MAV_0320|M.avium_104 --MNFVQRAIAYLLSADNWTGPVGLAARILEHLEYTGIAVGASALIAVPV
. *: .: . .: :
Mb3783c|M.bovis_AF2122/97 GLLVQRAPLLRRLTTATASVIFTIPSLALFVVLPLIIGTRILDEANVIVA
Rv3757c|M.tuberculosis_H37Rv GLLVQRAPLLRRLTTATASVIFTIPSLALFVVLPLIIGTRILDEANVIVA
Mvan_5599|M.vanbaalenii_PYR-1 GALVQRTTVLRRLTTVTASIVFTIPSLALFVVLPLIIPTRILDEANVIVA
MUL_0034|M.ulcerans_Agy99 GVLIYNSPLRVAAGNAVTAVGLTIPSYALLGVLVGIVG---LGVLPSVIM
MMAR_0035|M.marinum_M GVLIYNSPLGVAAGNAVTAVGLTIPSYALLGVLVGIVG---LGVLPSVIM
MAB_1225|M.abscessus_ATCC_1997 GVLIYRSPWGVASGNALAAIGLTIPSYALLGVLVGVVG---IGVSPSVIM
MSMEG_2927|M.smegmatis_MC2_155 GVLIYRSPWASAIGNTLTSVGLTIPSYALLGVLVAFIG---IGVLPSVIM
TH_0698|M.thermoresistible__bu GVMLYRSTWGRSLGDSVTSLGLTVPSYALLGVLVGIFG---VGVLPSVVL
Mflv_3108|M.gilvum_PYR-GCK GVLTYRNSLAANLATATSSVILTVPSFALLGLLIPLFG---LGVIPSVAA
MAV_0320|M.avium_104 GLLIGHTGRGTLLVVGAVNGLRALPTLGVLLFGTLLFG---LGLGPSLVA
* : . ::*: .:: . .. :. :
Mb3783c|M.bovis_AF2122/97 LAAYTTALLVRAVLEALDAVPAQVHDAATAIGYSRIAQMLKVELPLSIPV
Rv3757c|M.tuberculosis_H37Rv LAAYTTALLVRAVLEALDAVPAQVHDAATAIGYSRIAQMLKVELPLSIPV
Mvan_5599|M.vanbaalenii_PYR-1 LTLYTVALLVRAVPEALDAVSPAVLDAATAVGYRPLTRMLKIELPLALPV
MUL_0034|M.ulcerans_Agy99 PTFFGVFPILRNVVVGLTGVDKGLVESARGMGMSRLTTLVRLELPLAWPV
MMAR_0035|M.marinum_M LTFFGVFPILRNVVVGLTGVDKGLVESARGMGMSRLTTLVRLELPLAWPV
MAB_1225|M.abscessus_ATCC_1997 LVFFGSLPILRNVLVGLTGVDQTLVESARGMGMSRLATLVRLELPLAWPV
MSMEG_2927|M.smegmatis_MC2_155 LVFFGFLPILRNVLVGLGGVDRALIESARGMGMSRLSTLLRLEIPLAWPV
TH_0698|M.thermoresistible__bu LTFFGFLPILRNVLVGLNGVDAGLVESARAMGMSRPATLLRLELPLAWPV
Mflv_3108|M.gilvum_PYR-GCK LVLYSLLPIIRNTIVGLNAVDPALTDAARGIGLSRLQTLGRVELRLVWPA
MAV_0320|M.avium_104 LMLLGVPALLAGTYAGIANVEPTVVDAARAMGMTESQVLLRVEVPNALPL
:: . .: * : ::* .:* : ::*: *
Mb3783c|M.bovis_AF2122/97 LVAGLRVVAVTNIAMVSVGSVIGIGGLGTWFTAGYQ----TNKSDQIVAG
Rv3757c|M.tuberculosis_H37Rv LVAGLRVVAVTNIAMVSVGSVIGIGGLGTWFTAGYQ----TNKSDQIVAG
Mvan_5599|M.vanbaalenii_PYR-1 LIASLRVVAVTNISMVAVGSVIGIGGLGTWFTEGYQ----ANKSDQIIAG
MUL_0034|M.ulcerans_Agy99 IMTGVRVSAQMLMGIAAIVAFALGPGLGGYIFSGISRMGGANATNSIVAA
MMAR_0035|M.marinum_M IMTGVRVSAQMLMGIAAIVAFALGPGLGGYIFSGISRMGGANATNSIVAA
MAB_1225|M.abscessus_ATCC_1997 IMTGIRVSAQMLMGTAAIAAFALGPGLGGYIFSGISRMGGANATNSVIAG
MSMEG_2927|M.smegmatis_MC2_155 IMTGVRVSAQMLMGVAAIAAYALGPGLGGYIFSGISRTGGANATNSIVAG
TH_0698|M.thermoresistible__bu IMTGVRISAQMLMGIAAIAAFALGPGLGGYIFSGISRMGGANATNSIIVA
Mflv_3108|M.gilvum_PYR-GCK ILSAMRLSTQMSMGVLAIAAYVKGPGLGNLIFAGLARVGSPTALPMALSG
MAV_0320|M.avium_104 ILGGLRSATLQVVATATVAAYASLGGLGRYLIDGIK----EREFHLALVG
:: .:* : :. :: : *** : * : .
Mb3783c|M.bovis_AF2122/97 VVAMFLLAIVVDVVINLAGRLATPWERA-PRAARRRRQVAAPITGGAR
Rv3757c|M.tuberculosis_H37Rv VVAMFLLAIVVDVVINLAGRLATPWERA-PRAARRRRQVAAPITGGAR
Mvan_5599|M.vanbaalenii_PYR-1 IVAIFVLAIVIDTLIMLAGKALTPWTRAQPRATRAPRAEAGAPT----
MUL_0034|M.ulcerans_Agy99 TIGILILAVILDTVLNVIARLTT------PREIRA-------------
MMAR_0035|M.marinum_M TIGILILAVILDTVLNLIARLTT------PRGIRA-------------
MAB_1225|M.abscessus_ATCC_1997 TVGILILAVILDSVLNVVTRLTT------PRGIRV-------------
MSMEG_2927|M.smegmatis_MC2_155 TVGILILAVVLDTVLNIITRLTT------PRGIRV-------------
TH_0698|M.thermoresistible__bu TVGILLLAVILDAVLNLVTRLTT------PRGIRV-------------
Mflv_3108|M.gilvum_PYR-GCK TLLIVILALLLDAALVLLGRLTT------SKGIR--------------
MAV_0320|M.avium_104 ALTVAALALVLDGLLAVAVWASVPGTGRLRRTYRPLPHRLAGTSYGR-
: : **:::* : : . : *