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CPVSDMRPVHDWFLQRGLPLVLPRRVRARKLVQRSAPMVSAVGALTAVTMLLADVTGSDPDYGYAVRLGA IAVILIAAPFALEILHRLGTRMGEALRRWAALLVMTIFVVIMPLTVSGWSGTAAAEAPVFIVISLLAVWL TYLGFGSIALWAFRFAWVQVGALGTLMSRALPLLMLTVVVYFTGELWQLSARMSRERLWQTIGFLSLVAL LFMVATIRDEVRALRQERSERDDDATALLEDTPLASIHTGPAARTPLSLAEQANVVAVMVVAQAIQVVLF TAGLFVFFLALGMIAIPDDVTVLWSSEQTCAVGEPPCAGTWFGVHIPIPQTVVHMSLFVAVLSGLYFTVS TSVDPLYRERFFEPLIGDVAVSLAGRDAYRAVGQPDRFTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3072 | - | - | 100% (391) | hypothetical protein Mflv_3072 |
| M. gilvum PYR-GCK | Mflv_3074 | - | 3e-44 | 31.89% (392) | hypothetical protein Mflv_3074 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2137 | - | 3e-36 | 29.52% (376) | integral membrane protein |
| M. tuberculosis H37Rv | Rv2113 | - | 9e-37 | 29.52% (376) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3089 | - | 6e-45 | 29.49% (373) | integral membrane protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2335 | - | 1e-30 | 28.08% (260) | integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_3454 | - | 0.0 | 87.00% (377) | hypothetical protein Mvan_3454 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3089|M.marinum_M MNPSPHRAPARRDPSSAAAESWFLERGLPAVLTRRARWRRLWSRSAPVLA
MUL_2335|M.ulcerans_Agy99 -----------------------------------------MSRHEPFPA
Mb2137|M.bovis_AF2122/97 MSLSVRRPPAARAAAIVEAESWFLKRGLPSVLTMRGRCRRLWPRSAPMLA
Rv2113|M.tuberculosis_H37Rv MSLSVRRPPAARAAAIVEAESWFLKRGLPSVLTMRGRCRRLWPRSAPMLA
Mflv_3072|M.gilvum_PYR-GCK ---------MCPVSDMRPVHDWFLQRGLPLVLPRRVRARKLVQRSAPMVS
Mvan_3454|M.vanbaalenii_PYR-1 ---------------MRRVHDWFLHRGLPLVLTRRVRARKLVQRSAPMVS
* *. :
MMAR_3089|M.marinum_M AYATLHCWTLPILLITHGDEVVIDGQPTPREWVLVTLVAIAPVLITFVGW
MUL_2335|M.ulcerans_Agy99 PRS---------------------GTPRPVECRGGKLVS---------GT
Mb2137|M.bovis_AF2122/97 AWAVVEGCLMAVFFVTDGGEVFISATPTTAQWVILALLAVALPLASLVGW
Rv2113|M.tuberculosis_H37Rv AWAVVEGCLMAVFFVTDGGEVFISATPTTAQWVILALLAVALPLASLVGW
Mflv_3072|M.gilvum_PYR-GCK AVGALTAVTMLLADVTGSDPDYGYAVRLGAIAVILIAAPFALEILHRLGT
Mvan_3454|M.vanbaalenii_PYR-1 AVGALTAVTMLLADVTGESPDYGYAVRLGGIAVVLVAAPFVLEVLHRLGT
. . . . *
MMAR_3089|M.marinum_M LVSRLSDSRMRSVAATVAVSLVAIVLIVET--SVSHLPDAALAAVMVLLL
MUL_2335|M.ulcerans_Agy99 GLARGAD-QAGPLAATVAVSLVAIVLIVET--SVSHLPDAALAAVMVLLL
Mb2137|M.bovis_AF2122/97 LVSQISSGRGQAAVATMAVAFAAASDVIES--GPIQLLRTAVVVGLVLLQ
Rv2113|M.tuberculosis_H37Rv LVSQISSGRGQAAVATMAVAFAAASDVIES--GPIQLLRTAVVVGLVLLQ
Mflv_3072|M.gilvum_PYR-GCK RMGEALRRWAALLVMTIFVVIMPLTVSGWSGTAAAEAPVFIVISLLAVWL
Mvan_3454|M.vanbaalenii_PYR-1 RVGEALRRWAAVLVMTIFVVVMPLTVSGWSGAAAAEAPAFILISLTAIWL
:.. . *: * . . : . . : .:
MMAR_3089|M.marinum_M TGSGIGSVTGWSVRMTLSHLATIGALAVRALPVVLLTTLVFFNSNIWLMA
MUL_2335|M.ulcerans_Agy99 TGSGIGSVTGWSVRMTLSHLATIGALAVRALPVVLLTTLVFFNSNIWLMA
Mb2137|M.bovis_AF2122/97 TGCGVGSVLGWAVRMTLEHLATVGTLAVRALPIVLLTALVFFNTYVWLMA
Rv2113|M.tuberculosis_H37Rv TGCGVGSVLGWAVRMTLEHLATVGTLAVRALPIVLLTALVFFNTYVWLMA
Mflv_3072|M.gilvum_PYR-GCK TYLGFGSIALWAFRFAWVQVGALGTLMSRALPLLMLTVVVYFTGELWQLS
Mvan_3454|M.vanbaalenii_PYR-1 TYLGFGSIALWAFRFAWVQLGALGTLMSRALPLLMLTVVVYFTGELWQLS
* *.**: *:.*:: ::.::*:* ****:::**.:*:*. :* ::
MMAR_3089|M.marinum_M STISAERLALAIAFLVGIASVFVISTTAERVKPMLQAPTVQPK-NCQELA
MUL_2335|M.ulcerans_Agy99 STISAERLALAIAFLVGIASVFVISTTAERVKPMLQAPTVQPK-NCQELA
Mb2137|M.bovis_AF2122/97 ANINGERLPLAMVFLLAIAGAFVVSKTVERVRPLLRSTTVMPQ-GSQSLA
Rv2113|M.tuberculosis_H37Rv ANINGERLTLAMVFLLAIAGAFVVSKTVERVRPLLRSTTVMPQ-GSQSLA
Mflv_3072|M.gilvum_PYR-GCK ARMSRERLWQTIGFLSLVALLFMVATIRDEVRALRQERSERDDDATALLE
Mvan_3454|M.vanbaalenii_PYR-1 ARMTRERLWQTIGFLSIVALVFMIATIRDEVGALRQDRSARED-PAALLV
: :. *** :: ** :* *:::. :.* .: : : . *
MMAR_3089|M.marinum_M DTPFAAMPD-PPSSRPLTRAERANVVFVLTAHQLVQIMVVAMLTATIYVI
MUL_2335|M.ulcerans_Agy99 DTPFAAMPD-PPSSRPLTRAERANVVFVLTAHQLVQIMVVAMLTATIYVI
Mb2137|M.bovis_AF2122/97 GTPFATMGD-PSPGFPLTRAERLNVVFLLAALQLVEILVVASVGAAIYLV
Rv2113|M.tuberculosis_H37Rv GTPFATMGD-PSPGFPLTRAERLNVVFLLAASQLVEILVVASVGAAIYLV
Mflv_3072|M.gilvum_PYR-GCK DTPLASIHTGPAARTPLSLAEQANVVAVMVVAQAIQVVLFTAGLFVFFLA
Mvan_3454|M.vanbaalenii_PYR-1 GTPLESVRADPATRTPLSMAEQANVVAVMVVAQAIQVVLFTAGLFAFFLA
.**: :: *.. **: **: *** ::.. * :::::.: .:::
MMAR_3089|M.marinum_M LGLIVLSPALLQEWSHNVSSNA-------TVLGLTVPVPDSLIHLCLFIG
MUL_2335|M.ulcerans_Agy99 LELIVLSPALLQEWSHNVSSNA-------TVLGLTVPVPDSLIHLCLFIG
Mb2137|M.bovis_AF2122/97 LGMIILTPPLLREWTHYDSMTT-------TVLGMTFPAPDSLIRMCLFLG
Rv2113|M.tuberculosis_H37Rv LGMIILTPPLLREWTHYDSMTT-------TVLGMTFPAPDSLIRMCLFLG
Mflv_3072|M.gilvum_PYR-GCK LGMIAIPDDVTVLWSSEQTCAVGEPPCAGTWFGVHIPIPQTVVHMSLFVA
Mvan_3454|M.vanbaalenii_PYR-1 LGVIAIPDDVTVVWSGEQACAVGEPPCAGTWFGVHIPIPQTVVHTSLFVA
* :* :. : *: : . * :*: .* *::::: .**:.
MMAR_3089|M.marinum_M ALTFMYISARAVGDAEYRATFVDPLIENLHITLIARGRYRANIDDT---D
MUL_2335|M.ulcerans_Agy99 ALTFMYISARAVGDAEYRATFVDPLIENLHITLIAPGRYGANIDDT---D
Mb2137|M.bovis_AF2122/97 ALTFMYISARAVDDAEYRAMFLDPLIDDLHTALLARNRYRNNVVTAPCAG
Rv2113|M.tuberculosis_H37Rv ALTFMYISARAVDDAEYRAMFLDPLIDDLHTALLARNRYRNNVVTAPCAG
Mflv_3072|M.gilvum_PYR-GCK VLSGLYFTVSTSVDPLYRERFFEPLIGDVAVSLAGRDAYRAVGQPDRFTA
Mvan_3454|M.vanbaalenii_PYR-1 VLSGLYFTVSTSVDPLYRQRFFDPLIADVAVSLAGRDAYLEVERHQTRHG
.*: :*::. : *. ** *.:*** :: :* . . *
MMAR_3089|M.marinum_M VDASPGGD
MUL_2335|M.ulcerans_Agy99 VDASPGGD
Mb2137|M.bovis_AF2122/97 VDAGHVDD
Rv2113|M.tuberculosis_H37Rv VDAGHVDD
Mflv_3072|M.gilvum_PYR-GCK --------
Mvan_3454|M.vanbaalenii_PYR-1 --------