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VSDGEQAKPRRRRGRRRGHRRAQRAAGPPAAGAEHHTEPAADARTESRADTRSDTSSAPTPATQPGEKKP GPGRGSRAGAAKPTPKDQPKQRKNRPRRPPDRLRTVHETSAGGLVIDGIDGPKDSQVAALIGRLDRRGRM LWSLPKGHIELGETAEQTAIREVAEETGIQGSVLAALGSIDYWFVTEGRRVHKTVHHYLMRFLGGELSDD DVEVTEVAWVPLRELPSRLAYADERRLAEVAGELIDKLHTGGPAALPPLPHSAPRRRAQTHSHTRNRRDD TAQPQARRRTNGCGQGP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6927 | - | - | 100% (297) | MutT/nudix family protein |
| M. smegmatis MC2 155 | MSMEG_2390 | - | 8e-10 | 35.42% (96) | hydrolase, NUDIX family protein |
| M. smegmatis MC2 155 | MSMEG_3745 | - | 7e-06 | 35.45% (110) | MutT/nudix family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3938 | - | 3e-99 | 66.22% (299) | hypothetical protein Mb3938 |
| M. gilvum PYR-GCK | Mflv_0844 | - | 1e-117 | 73.15% (298) | NUDIX hydrolase |
| M. tuberculosis H37Rv | Rv3908 | - | 3e-99 | 66.22% (299) | hypothetical protein Rv3908 |
| M. leprae Br4923 | MLBr_02698 | - | 2e-95 | 64.31% (297) | hypothetical protein MLBr_02698 |
| M. abscessus ATCC 19977 | MAB_4935 | - | 3e-90 | 64.21% (285) | MutT/NUDIX family protein |
| M. marinum M | MMAR_5472 | - | 4e-99 | 65.66% (297) | hypothetical protein MMAR_5472 |
| M. avium 104 | MAV_5296 | - | 1e-97 | 64.98% (297) | MutT/nudix family protein |
| M. thermoresistible (build 8) | TH_0513 | - | 3e-93 | 81.34% (209) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_5061 | - | 3e-99 | 65.66% (297) | hypothetical protein MUL_5061 |
| M. vanbaalenii PYR-1 | Mvan_6062 | - | 1e-115 | 73.15% (298) | NUDIX hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_02698|M.leprae_Br4923 -----MP--AIIAWVSD--GEQAKPRRRRKRRRGRD--------ATRSAE
MAV_5296|M.avium_104 --------------MSD--GEQGKPRRRRGRRRGRG--------AATSSE
Mb3938|M.bovis_AF2122/97 --------------MSD--GEQAKSRRRRGRRRGRR--------AAATAE
Rv3908|M.tuberculosis_H37Rv --------------MSD--GEQAKSRRRRGRRRGRR--------AAATAE
MMAR_5472|M.marinum_M --------------MSE--GEQAKPRRRRGRRRGRG--------AARSAE
MUL_5061|M.ulcerans_Agy99 --------------MSE--GEQAKPRRRRGRRRGRG--------AARSAE
Mflv_0844|M.gilvum_PYR-GCK MRSGRVPPATIIAGVSD--GEQAKPRRRRGRRRGRR--------AAGPPE
Mvan_6062|M.vanbaalenii_PYR-1 -----MP--ATIAWVSD--GEQAKPRRRRGRRRGRR--------AAGPPE
MSMEG_6927|M.smegmatis_MC2_155 --------------MSD--GEQAKPRRRRGRRRGHRRAQRAAGPPAAGAE
TH_0513|M.thermoresistible__bu --------------------------------------------------
MAB_4935|M.abscessus_ATCC_1997 --MSDSSGGSRTGGSSDEPGSNPASARGRGSRRGRRNR------SQGRAQ
MLBr_02698|M.leprae_Br4923 NHTD--------------RQVANDATAT----------------------
MAV_5296|M.avium_104 KQTN--------------GQLTGDSTAT----------------------
Mb3938|M.bovis_AF2122/97 NHMD--------------AQPAGDATPTPA--------------------
Rv3908|M.tuberculosis_H37Rv NHMD--------------AQPAGDATPTPA--------------------
MMAR_5472|M.marinum_M NHTD--------------KAESTDPNPAP---------------------
MUL_5061|M.ulcerans_Agy99 NHTD--------------NAGSPDPNPAP---------------------
Mflv_0844|M.gilvum_PYR-GCK AGTDQAPGARQQN-SGARQQSSGAGTADQA--------------------
Mvan_6062|M.vanbaalenii_PYR-1 ALPDQAADHR--------QQAPPAGTAGQA--------------------
MSMEG_6927|M.smegmatis_MC2_155 HHTEPAADARTESRADTRSDTSSAPTPATQPGEKKPGPGRGSRAGAAKPT
TH_0513|M.thermoresistible__bu --------------------------------------------------
MAB_4935|M.abscessus_ATCC_1997 GRAQGAN-------TPAASPAAGAPAAPNG------------------AN
MLBr_02698|M.leprae_Br4923 ---KPRRSHSPHRA-PEQLRTVHETSAGGLVIYGIDGPRDAQVAALIGRI
MAV_5296|M.avium_104 ---KPRRSRAARRA-PDRLRTVHETSAGGLVIDGLDGPRESQVAALIGRI
Mb3938|M.bovis_AF2122/97 -TAKRSRSRSPRRG-STRMRTVHETSAGGLVIDGIDGPRDAQVAALIGRV
Rv3908|M.tuberculosis_H37Rv -TAKRSRSRSPRRG-STRMRTVHETSAGGLVIDGIDGPRDAQVAALIGRV
MMAR_5472|M.marinum_M --TKGRRPRLPRRGRPDRLRTVHETSAGGLVIDGIDGPRDEQVAALIGRI
MUL_5061|M.ulcerans_Agy99 --TKGRRPRLPRRGRPDRLRTVHETSAGGLVIDGIDGPRDAQVAALIGRI
Mflv_0844|M.gilvum_PYR-GCK -GQPPKPQRTRTRRPQERLRTVHETSAGGLVIDGLDGPKDSQVAALIGRV
Mvan_6062|M.vanbaalenii_PYR-1 -RQTPKPQRTRTRRPPERLRTVHETSAGGLVIDGIDGPKDGQVAALIGRI
MSMEG_6927|M.smegmatis_MC2_155 PKDQPKQRKNRPRRPPDRLRTVHETSAGGLVIDGIDGPKDSQVAALIGRL
TH_0513|M.thermoresistible__bu ------------------LRTVHETSAGGLVIDGLDGPKEKQVAALIGRL
MAB_4935|M.abscessus_ATCC_1997 TAAGKGRGRVKGRAAGTSLRTVRETSAGGLVIAGIDGPKDGQVAALIGRT
:***:********* *:***:: ********
MLBr_02698|M.leprae_Br4923 DRRGRMLWSLPKGHIEQGETAEQTAIREVAEETGIRGSVLAALGQIDYWF
MAV_5296|M.avium_104 DRRGRMLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWF
Mb3938|M.bovis_AF2122/97 DRRGRLLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWF
Rv3908|M.tuberculosis_H37Rv DRRGRLLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWF
MMAR_5472|M.marinum_M DRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGISGGVLAALGRIDYWF
MUL_5061|M.ulcerans_Agy99 DRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGIRGGVLAALGRIDYWF
Mflv_0844|M.gilvum_PYR-GCK DRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGIEGSVLAALGSIDYWF
Mvan_6062|M.vanbaalenii_PYR-1 DRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGIQGSVLAALGSIDYWF
MSMEG_6927|M.smegmatis_MC2_155 DRRGRMLWSLPKGHIELGETAEQTAIREVAEETGIQGSVLAALGSIDYWF
TH_0513|M.thermoresistible__bu DRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGVQGAVLAALGSIDYWF
MAB_4935|M.abscessus_ATCC_1997 DRRGRMLWSLPKGHIEQGETAEQTAIREVAEETGIRGTVLAALGSIDYWF
*****:********** *****************: * ****** *****
MLBr_02698|M.leprae_Br4923 VTDDCRVHKTVHHYLMRFSGGELSDDDLEVTEVAWVPIRELPSRLAYADE
MAV_5296|M.avium_104 VTDGRRVHKTVHHYLMRFSGGELSDEDLEVAEVAWVPMRELPSRLAYADE
Mb3938|M.bovis_AF2122/97 VTDGRRVHKTVHHYLMRFLGGELSDEDLEVAEVAWVPIRELPSRLAYADE
Rv3908|M.tuberculosis_H37Rv VTDGRRVHKTVHHYLMRFLGGELSDEDLEVAEVAWVPIRELPSRLAYADE
MMAR_5472|M.marinum_M VTDGRRVHKTVHHYLMRFLGGELSDNDLEVTEVAWVPIPELPSRLAYADE
MUL_5061|M.ulcerans_Agy99 VTDGRRVHKTVHHYLMRFLGGELSDNDLEVTEVAWVPIPELPSRLAYADE
Mflv_0844|M.gilvum_PYR-GCK VTEGRRVHKTVHHYLMRFLGGELSDEDVEVTEVAWVPLKDLPSRLAYADE
Mvan_6062|M.vanbaalenii_PYR-1 VTEGRRVHKTVHHYLMRFSGGELSDEDVEVTEVAWVPVKDLPSRLAYADE
MSMEG_6927|M.smegmatis_MC2_155 VTEGRRVHKTVHHYLMRFLGGELSDDDVEVTEVAWVPLRELPSRLAYADE
TH_0513|M.thermoresistible__bu VTEGRRVHKTVHHYLMRFLGGELSDDDVEVSEVAWVPLSELPTRLAYADE
MAB_4935|M.abscessus_ATCC_1997 VTEGRRVHKTVHHYLMRSLGGELSDDDVEVTEVAWVPLGELPTRLAYADE
**:. ************ ******:*:**:******: :**:*******
MLBr_02698|M.leprae_Br4923 RRLAEVAYELINKLQTGGPAALPPLPPSLPRRQSQTHFRT-----RHSNN
MAV_5296|M.avium_104 RRLARVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRTRHSETRHSDK
Mb3938|M.bovis_AF2122/97 RRLAEVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRA-----RHADD
Rv3908|M.tuberculosis_H37Rv RRLAEVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRA-----RHADD
MMAR_5472|M.marinum_M RRLAEVADELIDKLQTDGPTALPPLPPSAPRRRPQTHSRT-----RHAAE
MUL_5061|M.ulcerans_Agy99 RRLAEVADELIDKLQTDGPTALPPLPPSAPRRRPQTHSRT-----RHAAE
Mflv_0844|M.gilvum_PYR-GCK RKLAEVADELIDKLHTEGPGALPPLPHSAPRRRGQTHSHTR----KHRSD
Mvan_6062|M.vanbaalenii_PYR-1 RRLAEVADELIDKLHTDGPGALPPLPRTTPRRRGQTHSHTR----RHRPD
MSMEG_6927|M.smegmatis_MC2_155 RRLAEVAGELIDKLHTGGPAALPPLPHSAPRRRAQTHSHT-----RNRRD
TH_0513|M.thermoresistible__bu RRLAEVAGELIDTLQTHGPQALPPLPQMAPRRRPQTHSRTRSS--RRRDD
MAB_4935|M.abscessus_ATCC_1997 RRLAEVAGDLIDKLHTEGPAALPPLPPSAPRRRPQTHSST------HRTP
*:**.** :**:.*:: ** ****** ***: *** : .
MLBr_02698|M.leprae_Br4923 -SANSR---------------KNGHGQGP
MAV_5296|M.avium_104 -PATGR---------------KNGHGPGP
Mb3938|M.bovis_AF2122/97 -SAPGQ---------------HNGPGPGP
Rv3908|M.tuberculosis_H37Rv -SAPGQ---------------HNGPGPGP
MMAR_5472|M.marinum_M GSPPGR---------------KNGHGPGP
MUL_5061|M.ulcerans_Agy99 GSPPGR---------------KNGHGPGP
Mflv_0844|M.gilvum_PYR-GCK PSAQQQP-----------GRRTNGCGQGP
Mvan_6062|M.vanbaalenii_PYR-1 PTAQPQP-----------GRRTNGCGQGP
MSMEG_6927|M.smegmatis_MC2_155 DTAQPQA-----------RRRTNGCGQGP
TH_0513|M.thermoresistible__bu SAAHSRGEGRERGAANSSGRRTNGCGKGP
MAB_4935|M.abscessus_ATCC_1997 ----GR---------------RSGRGQQQ
: .* *