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AIVLALTLGDSAGTGWADPAADALARLTEFSREAERTTEAVYSAELDLEAKLGAQRRAEDRQRTELEAMT AARADLGEYQAAVNQVAAAAYMGGSTSTISAALTAESPQRLLDELSSSRVMATHMSNRISAFRAASTRAD EAALAAQSSALAARTAAEQASAVRADLQSKQSRLRTQIAEVEALYRALTPDQRAALADPGPMPPAPPVPP AANPAIMAMPEAIPPVGPGPSSSPEGTGVVQAALTRVGAPYSWGATGPDAFDCSGLIKWAFLQNGKSLPR SSQALAAGGQPVATTEVQPGDIVTFYSDASHAGIYIGDGNMVHASTYGTPVKVAPISSAPIYNVRRY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2808 | - | - | 100% (348) | NLP/P60 protein |
| M. gilvum PYR-GCK | Mflv_0888 | - | e-116 | 65.17% (333) | NLP/P60 protein |
| M. gilvum PYR-GCK | Mflv_2959 | - | e-113 | 60.40% (346) | NLP/P60 protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2213c | - | 1e-104 | 59.03% (349) | hypothetical protein Mb2213c |
| M. tuberculosis H37Rv | Rv2190c | - | 1e-104 | 59.03% (349) | hypothetical protein Rv2190c |
| M. leprae Br4923 | MLBr_00885 | - | 2e-96 | 51.91% (341) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_1974 | - | 2e-97 | 52.79% (358) | hypothetical protein MAB_1974 |
| M. marinum M | MMAR_3234 | - | 1e-101 | 56.15% (358) | hypothetical protein MMAR_3234 |
| M. avium 104 | MAV_2304 | - | 2e-97 | 54.52% (343) | NLP/P60 family protein |
| M. smegmatis MC2 155 | MSMEG_4256 | - | 1e-109 | 57.82% (358) | NLP/P60 family protein |
| M. thermoresistible (build 8) | TH_3014 | - | 1e-105 | 56.67% (360) | PUTATIVE NLP/P60 family protein |
| M. ulcerans Agy99 | MUL_3545 | - | 1e-97 | 53.89% (360) | hypothetical protein MUL_3545 |
| M. vanbaalenii PYR-1 | Mvan_3713 | - | 0.0 | 95.11% (348) | NLP/P60 protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2808|M.gilvum_PYR-GCK -----------------------MAIVLALTLGD---SAGTGWADPAADA
Mvan_3713|M.vanbaalenii_PYR-1 -----------------------MAIVLALTLGN---SAGIGWADPAADA
Mb2213c|M.bovis_AF2122/97 ------MRLDQRWLIARVIMRSAIGFFASFTVSSGV-LAANVLADPADDA
Rv2190c|M.tuberculosis_H37Rv ------MRLDQRWLIARVIMRSAIGFFASFTVSSGV-LAANVLADPADDA
MMAR_3234|M.marinum_M ------MRLDCRQLTARVIRRSAIGSLASFTALSGF-VAAGAMADPAEDA
MUL_3545|M.ulcerans_Agy99 ------MRLDCRQLTARVIRRSAIGSLASFTALSGF-VAAGAMADQAEDA
MAV_2304|M.avium_104 --------------------------------------------------
MLBr_00885|M.leprae_Br4923 ------MRLGCKHPVVRLIAHFVVGTLVGFAVLSRF-FVATAMADPAEDA
MSMEG_4256|M.smegmatis_MC2_155 ------MRHARAHRPTSRFKRPIAGAIASLALGAGL-LAGSVQADPADDA
TH_3014|M.thermoresistible__bu ------LRIDRAHRIIRSVHRPLIALIAGLTLLATG-IAAPGHADPADDA
MAB_1974|M.abscessus_ATCC_1997 MSVGRLLRNHSDRLTPSPLRRAMLAVTAAALVGGVFTGAQTATADPNNDA
Mflv_2808|M.gilvum_PYR-GCK LARLTEFSREAERTTEAVYSAELDLEAKLGAQRRAEDRQRTELEAMTAAR
Mvan_3713|M.vanbaalenii_PYR-1 LARLTELSREAEQTTEAVYSAELDLEAKLAAQRRAEDRQRAELEAMTAAR
Mb2213c|M.bovis_AF2122/97 LAKLNELSRQAEQTTEALHSAQLDLNEKLAAQRAADQKLADNRTALDAAR
Rv2190c|M.tuberculosis_H37Rv LAKLNELSRQAEQTTEALHSAQLDLNEKLAAQRAADQKLADNRTALDAAR
MMAR_3234|M.marinum_M LAKLNELSRQAEQTTEAMHSAELDLGAKLAAQQAAENKLTDDQAALDAAK
MUL_3545|M.ulcerans_Agy99 LAKLNELSRQAEQTTEAMHSAELELGAKLAAQQAAENKLTDDQAALDATK
MAV_2304|M.avium_104 MAKLNELSRQAEQTTEAMHSAQLDLNEKLAAQRAAEKKHDDDQAAVDAAK
MLBr_00885|M.leprae_Br4923 LAKLNELSRQAEQTTEAVHSAQLDLTEKLAAQRAADKKYTDDQAALADAQ
MSMEG_4256|M.smegmatis_MC2_155 LAKLNELSRQAEQTTEAMHSAQLDLDNKLAAQQAAEKKHSEDAAAAEQAR
TH_3014|M.thermoresistible__bu LAKLQELSRQAEQTTEAMHSARLDLEEKLAAQRAAEEKAAADAAAADAAT
MAB_1974|M.abscessus_ATCC_1997 VKKLNELSRQAEATSEAANTAKIDLDAKLAAQRDAEKTVLADEAVAKAAR
: :* *:**:** *:** :*.::* **.**: *:. : . :
Mflv_2808|M.gilvum_PYR-GCK ADLGEYQAAVNQVAAAAYMGGSTSTISAALTAESPQRLLDELSSSRVMAT
Mvan_3713|M.vanbaalenii_PYR-1 ADLGEYQAAVNQVAAASYMGGSTSTISAALTAESPQRLLDELSSSRVMAT
Mb2213c|M.bovis_AF2122/97 ARLATFQTAVNKVAAATYMGGRTHGMDAILTAESPQLLIDRLSVQRVMAH
Rv2190c|M.tuberculosis_H37Rv ARLATFQTAVNKVAAATYMGGRTHGMDAILTAESPQLLIDRLSVQRVMAH
MMAR_3234|M.marinum_M GQLASFQTAVNKVAAAAYMGGRANGMDTILTAPSPQLLIDGLSMQRVMAH
MUL_3545|M.ulcerans_Agy99 GQLASFQTAVNKVAAAAYMGGRANGMDTILTAPSPQLLIDGLSMQRVMVH
MAV_2304|M.avium_104 AHLASYQNAVNNLAAATYMGGRVDGMEAILTAGSPQGLIDKLAVQRLMAT
MLBr_00885|M.leprae_Br4923 VRLATFQAAVNKLAAATYMSGRINGMTALLTAYSPQQLINKLALQRVLGV
MSMEG_4256|M.smegmatis_MC2_155 AQLATFQASVNRVAAAQYMGGRTSGVDAILTADSPQQLIDQLAVQRVMAT
TH_3014|M.thermoresistible__bu AQLANYQTAVDKLAASQYMGGRTDGFNAILTARSPQQLIDQLAVQRVMAT
MAB_1974|M.abscessus_ATCC_1997 MAVSTYQVDVNKAMVAAYMGGTTSGYGAVLTSNSPQNLIDQLSVQRTVGG
:. :* *:. .: **.* : **: *** *:: *: .* :
Mflv_2808|M.gilvum_PYR-GCK HMSNRISAFRAASTRADEAALAAQSSALAARTAAEQASAVRADLQSKQSR
Mvan_3713|M.vanbaalenii_PYR-1 QMSDRIKAFRAASTRADDAARAAQSSALAARTAAEQASAVRASLQSKQSR
Mb2213c|M.bovis_AF2122/97 QMSTQMARFKAAGEQAVKAEQAAAKSAADARSAAEQAAAVRANLQHKQSQ
Rv2190c|M.tuberculosis_H37Rv QMSTQMARFKAAGEQAVKAEQAAAKSAADARSAAEQAAAVRANLQHKQSQ
MMAR_3234|M.marinum_M QMATQMSGFRTAREQAAKAEQASEKSAADAKSAAEQAAAVRANLQHKQSQ
MUL_3545|M.ulcerans_Agy99 QMATQMSGFRTAREQTAKAEQASEKSAADAKSAAEQAAAVRANLQHKQSQ
MAV_2304|M.avium_104 QMASQMKSYRIAGEQAAKAERESAKSAADAKSAAEQAAAVRASLQSKQSQ
MLBr_00885|M.leprae_Br4923 QMATQMAGYRDAGEQAVKAEQTSAKSAADAKHAADQAAVVRAGLQSKQSK
MSMEG_4256|M.smegmatis_MC2_155 EMATQMQNFRSVGEKAAAAEQASAKSAAEAKTAAEQAAAVRAELQSKQSQ
TH_3014|M.thermoresistible__bu EMSEQMHRFRLAQEEAAKAAEASAKSAAEARTAAEQAAAVRAELQAKQSE
MAB_1974|M.abscessus_ATCC_1997 EMRSRMDSYRAAQTSADEAEQRSRDAAEAARVAAEQAKNVRASLQAKQSQ
.* :: :: . : * : .:* *: **:** *** ** ***.
Mflv_2808|M.gilvum_PYR-GCK LRTQIAEVEALYRALTPDQRAALADPGPMPPAPPVPPA-----------A
Mvan_3713|M.vanbaalenii_PYR-1 LRTQIAEVEALYRALTPDQRAALADPGPVPPAPPVPPA-----------A
Mb2213c|M.bovis_AF2122/97 LQVQIAVVKSQYVALTPEERTALADPGPVPAVAAIAPG-APPAALPPG-A
Rv2190c|M.tuberculosis_H37Rv LQVQIAVVKSQYVALTPEERTALADPGPVPAVAAIAPG-APPAALPPG-A
MMAR_3234|M.marinum_M LQVQIAVVKSQYLALTPDQRTALADPGQVPAGLPGAPG-PAPEGTPPGGP
MUL_3545|M.ulcerans_Agy99 LQVQIAVVKSQYLALTPDQRTALVDPGQVPAGLPGAPG-PAPEGTPPGGP
MAV_2304|M.avium_104 LQVQIAVVKSQYMSLTADQRTALANPGPAVPAAATAPGAPAPEAAPPG--
MLBr_00885|M.leprae_Br4923 LQLQIAVVKSHYLSLSPRQRTTLAEPGPVPAVAT-LPG-----AASAGVS
MSMEG_4256|M.smegmatis_MC2_155 LQVQIAIVKSQYEALTPQQREALATAPPPPAAPPAPAP-----DALPPAN
TH_3014|M.thermoresistible__bu LQQQIEVVKAQYEALTPDQREALAAMPP---VPPGTPT-----GELPGQH
MAB_1974|M.abscessus_ATCC_1997 LQVQIAVVKSQYNTLSPGQRAQLAAPAPVPPPPAAEPG-------EAGDA
*: ** *:: * :*:. :* *. . .
Mflv_2808|M.gilvum_PYR-GCK NPAIMAMP-EAIPP----VGPGPSSSPEG-----TGVVQAALTRVGAPYS
Mvan_3713|M.vanbaalenii_PYR-1 NPAIMAMP-EAIPP----VGPGPSSSPEG-----AAVVQAALTRVGAPYS
Mb2213c|M.bovis_AF2122/97 PPGDGPAPGVAPPP--GGMPGLPFVQPDGAGGDRTAVVQAALTQVGAPYA
Rv2190c|M.tuberculosis_H37Rv PPGDGPAPGVAPPP--GGMPGLPFVQPDGAGGDRTAVVQAALTQVGAPYA
MMAR_3234|M.marinum_M PPAGAPVPGEAPPP--GGVSAMPFTPPDGAGGDRAAVVQAALTQVGTPYA
MUL_3545|M.ulcerans_Agy99 PPAGAPVPGEAPPPGAGGVSAMPFTPPDGAGGDRAAVVQAALTQVGTPYA
MAV_2304|M.avium_104 TPPGGPGPGEAPPP--GGAPGMAPGGGGVGGGDRATVVQAALTQVGSPYV
MLBr_00885|M.leprae_Br4923 PPPD------AAPP--GGLLGVAP-APFAGGGDRAAVVQAALTQIGSPYA
MSMEG_4256|M.smegmatis_MC2_155 DPGVLAAPPEGIPP--GDIAPPDAAIPGGPSPVSNTVIQAALSRIGSPYS
TH_3014|M.thermoresistible__bu DTEVLAAP--GIPP--GDLAP-EAAVPGGPSNDRATVVQAALSRIGSPYS
MAB_1974|M.abscessus_ATCC_1997 PEPLMQAAAAAPAP--------EAAIGGGGSPAGAGAVAAALTRIGAPYS
. .* .: ***:::*:**
Mflv_2808|M.gilvum_PYR-GCK WGATGPDAFDCSGLIKWAFLQ-NGKSLPRSSQALAAGGQPVATTEVQPGD
Mvan_3713|M.vanbaalenii_PYR-1 WGATGPDAFDCSGLIKWAFLQ-NGKSLPRSSQALAAGGQPVATTEVQPGD
Mb2213c|M.bovis_AF2122/97 WGGAAPGGFDCSGLVMWAFQQ-AGIALPHSSQALAHGGQPVALSDLQPGD
Rv2190c|M.tuberculosis_H37Rv WGGAAPGGFDCSGLVMWAFQQ-AGIALPHSSQALAHGGQPVALSDLQPGD
MMAR_3234|M.marinum_M WGGAAPGGFDCSGLVMWAFQQ-AGIALPHSSQALAHGGQPVSLSDLQPGD
MUL_3545|M.ulcerans_Agy99 WGGAAPGGFDCSGLVMWAFQQ-AGIALPHSSQALAHEGQPVSLSDLQPGD
MAV_2304|M.avium_104 WGGAAPGGFDCSGLVMWAFQQ-AGISLPHSSQALAHGGQPVSLSDLQPGD
MLBr_00885|M.leprae_Br4923 WGGAAPGGFDCSGLVMWAYQQ-AGIALPHSSQALARGGQPVSLSELQPGD
MSMEG_4256|M.smegmatis_MC2_155 WGGSGPNAFDCSGLVMWSFQQ-AGISLPHSSQALARGGQPVSMDNIQPGD
TH_3014|M.thermoresistible__bu WGGSGPNAFDCSGLVMWAFRQGAGINLPHSSQALARGGQPVSMADIQPGD
MAB_1974|M.abscessus_ATCC_1997 WGGSGPNAFDCSGLVMWAYGQ-QGVSLPHSSQALARGGTPVSLSELQPGD
**.:.*..******: *:: * * **:****** * **: ::****
Mflv_2808|M.gilvum_PYR-GCK IVTFYSDASHAGIYIGDGNMVHASTYGTPVKVAPISS-APIYNVRRY
Mvan_3713|M.vanbaalenii_PYR-1 IVTFYSDASHAGIYIGDGNMVHASTYGTPVKVAPISS-APIYNVRRY
Mb2213c|M.bovis_AF2122/97 VLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMDSSGPIYDARRY
Rv2190c|M.tuberculosis_H37Rv VLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMDSSGPIYDARRY
MMAR_3234|M.marinum_M VLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMNSSGPIYDARRY
MUL_3545|M.ulcerans_Agy99 VLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMNSSGPIYDARRY
MAV_2304|M.avium_104 VLTFYSDASHAGIYIGDGMMIHSSTYGVPVRVVPMNSSGPIYDARRY
MLBr_00885|M.leprae_Br4923 VLTFYSDASHAGIYVGDGMMIHSSTYGVPVRVVPMNSSGPIYDARRY
MSMEG_4256|M.smegmatis_MC2_155 LVTYYSDASHVGIYIGDGMMVHASTYGSPVRVAPVNN-APIYNVRRY
TH_3014|M.thermoresistible__bu VVTYYSDASHAAIYIGNGMMVHASTYGTPVRVAPVNN-APIYNIRRY
MAB_1974|M.abscessus_ATCC_1997 VINFYGDASHTGIYVGNGMMVHASTYGVPVAVVPITSSGPIYNARRY
::.:*.****..**:*:* *:*:**** ** *.*: . .***: ***