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RGPRVGTTDASPRRTVNLATRAVMTTMVALGFWLCGVGVAAAHTSLVGSDPAKDASVASPLTAVVLIFSE EINPAFADVAVTSADGRNWVSGSANVEGPRLTVAVGPDRLTNGLFTVSYRVVSADGHPVSGSYTFTIAGV PEQPSPTTAPARAAPSTAEPSPPAPAATAGSDTKASVLTAAGAGLALGGVIAFWQSRRHRRKNAAEHPRS EPGRSGGQNTSPPSDRRD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2807 | - | - | 100% (229) | copper resistance protein CopC |
| M. gilvum PYR-GCK | Mflv_1127 | - | 3e-19 | 35.43% (175) | copper resistance protein CopC |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0461 | PPE11 | 8e-05 | 34.78% (115) | PPE family protein |
| M. tuberculosis H37Rv | Rv0453 | PPE11 | 8e-05 | 34.78% (115) | PPE family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0109c | - | 3e-17 | 31.64% (177) | copper resistance protein CopC |
| M. marinum M | MMAR_1100 | mycP4 | 9e-05 | 26.53% (98) | membrane-anchored serine protease (mycosin), MycP4 |
| M. avium 104 | MAV_0177 | - | 4e-18 | 34.97% (163) | copper resistance protein CopC |
| M. smegmatis MC2 155 | MSMEG_6436 | - | 2e-21 | 36.16% (177) | copper resistance protein CopC |
| M. thermoresistible (build 8) | TH_1515 | - | 3e-20 | 36.81% (163) | copper resistance protein CopC |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3714 | - | 1e-111 | 91.78% (219) | copper resistance protein CopC |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2807|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3714|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_0177|M.avium_104 --------------------------------------------------
TH_1515|M.thermoresistible__bu --------------------------------------------------
MSMEG_6436|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0109c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0461|M.bovis_AF2122/97 MTSALIWMASPPEVHSALLSSGPGPGPVLAAATGWSSLGREYAAVAEELG
Rv0453|M.tuberculosis_H37Rv MTSALIWMASPPEVHSALLSSGPGPGPVLAAATGWSSLGREYAAVAEELG
MMAR_1100|M.marinum_M MTSRFGHLLAACALAAPCWCAMPAAHAVTPPPVDERWLPQPAPPGPPSRT
Mflv_2807|M.gilvum_PYR-GCK --------------------------------MRGPRVGTTDASPRRTVN
Mvan_3714|M.vanbaalenii_PYR-1 --------------------------------MLARRT----RSSRRTVR
MAV_0177|M.avium_104 ------------------------------------------MRRWAVG-
TH_1515|M.thermoresistible__bu -----------------------------------MSSTSRAFTRTRVGP
MSMEG_6436|M.smegmatis_MC2_155 -------------------------------------MTPLHGARSRVLT
MAB_0109c|M.abscessus_ATCC_199 ----------------------------------------MAVLRKSVS-
Mb0461|M.bovis_AF2122/97 ALLAAVQAGVWQGPSAESFAAAC-----LPYLSWLTQASADCAAAAARLE
Rv0453|M.tuberculosis_H37Rv ALLAAVQAGVWQGPSAESFAAAC-----LPYLSWLTQASADCAAAAARLE
MMAR_1100|M.marinum_M RQREVCAAATWAPERPEAAAQLAGLDLPEAWRLTRGSGQRVAVIDTGVAH
Mflv_2807|M.gilvum_PYR-GCK LATRAVMTTMVALGFWLCGVGVAAAHTSLVGS------------------
Mvan_3714|M.vanbaalenii_PYR-1 LATRAVMTTLMALAFWLSGVGVAAAHTSLVGS------------------
MAV_0177|M.avium_104 -----ACVGALVLIAGLTAP-AAWAHAARVAT------------------
TH_1515|M.thermoresistible__bu ARILGAFAGILTVMGIVMAP-PAAAHATLMST------------------
MSMEG_6436|M.smegmatis_MC2_155 RLLSFALTALTLVAASLAGAGAASAHAALIST------------------
MAB_0109c|M.abscessus_ATCC_199 ----VFVSAFIALTLGLALPAVASAHAVKVSS------------------
Mb0461|M.bovis_AF2122/97 AVTAAYAAALVAMPTLAELAANHATHGAMVATNFFGINTIPIAVNEADYV
Rv0453|M.tuberculosis_H37Rv AVTAAYAAALVAMPTLAELAANHATHGAMVATNFFGINTIPIAVNEADYV
MMAR_1100|M.marinum_M HRRLAHLVAGGDYVFTGDGTQDCDAHGTIVAG-----------------I
:* :.
Mflv_2807|M.gilvum_PYR-GCK -------------DPAKDASVASPLTAVVLI-------------------
Mvan_3714|M.vanbaalenii_PYR-1 -------------DPAKDASVASPLTAVVLN-------------------
MAV_0177|M.avium_104 -------------DPAADAALTTGPHRVSAT-------------------
TH_1515|M.thermoresistible__bu -------------DPADGAVLEEAPERVSAT-------------------
MSMEG_6436|M.smegmatis_MC2_155 -------------DPAENTTLTESPQRVSAT-------------------
MAB_0109c|M.abscessus_ATCC_199 -------------DPAENAVLSGPPVQVSAT-------------------
Mb0461|M.bovis_AF2122/97 RMWLQAATTMATYQAVADSAVRSIPDSVPPPRILKSNAQSQHSSSNNSGG
Rv0453|M.tuberculosis_H37Rv RMWLQAATTMATYQAVADSAVRSIPDSVPPPRILKSNAQSQHSSSNNSGG
MMAR_1100|M.marinum_M IAAAPDSATDQFSGVAPDATVIGIRQSSAKFSPVGNRSSTGVGDVDTMAR
. .: :
Mflv_2807|M.gilvum_PYR-GCK -------FSEEINPAFADVAVTSADG------------------------
Mvan_3714|M.vanbaalenii_PYR-1 -------FSEEINPAFADVAVTSADG------------------------
MAV_0177|M.avium_104 -------FNEQLQTTFAAMTVVGPDG------------------------
TH_1515|M.thermoresistible__bu -------FNEPMQDTFAAMTVVGPDG------------------------
MSMEG_6436|M.smegmatis_MC2_155 -------FNEPMQQAFAAMTVVGPDG------------------------
MAB_0109c|M.abscessus_ATCC_199 -------FNEPLQKRFSAMTVIGPDDK-----------------------
Mb0461|M.bovis_AF2122/97 ADPVDDFIAEILKIITGGRVIWDPEAGTVNGLPYDAYTNPGTLMWWIARS
Rv0453|M.tuberculosis_H37Rv ADPVDDFIAEILKIITGGRVIWDPEAGTVNGLPYDAYTNPGTLMWWIARS
MMAR_1100|M.marinum_M AVRTAADLGASVINISTIACVAAESPPDDRALG-----------------
: : : .
Mflv_2807|M.gilvum_PYR-GCK ----------------------------------------RNWVSGSANV
Mvan_3714|M.vanbaalenii_PYR-1 ----------------------------------------RNWVSGSASV
MAV_0177|M.avium_104 ----------------------------------------NVWSTGEPTV
TH_1515|M.thermoresistible__bu ----------------------------------------NLWSTGEAEV
MSMEG_6436|M.smegmatis_MC2_155 ----------------------------------------NLWSTDDPQV
MAB_0109c|M.abscessus_ATCC_199 ---------------------------------------TDQWQAGDPVV
Mb0461|M.bovis_AF2122/97 LELLQDFQEFAKLLFTNPVKAFQFLVDLILFDWPTHMLQLATWLAENPQL
Rv0453|M.tuberculosis_H37Rv LELLQDFQEFAKLLFTNPVKAFQFLVDLILFDWPTHMLQLATWLAENPQL
MMAR_1100|M.marinum_M -----------------------------AALAYAVDVKNAVIVAAAGNT
:
Mflv_2807|M.gilvum_PYR-GCK EGPRLTVAVGPDRLTNGLFTVS-------YRVVSADGHPVSGSYTFTIAG
Mvan_3714|M.vanbaalenii_PYR-1 EGPRLTLAVGPERLTNGLYTVS-------YRVVSADGHPVSGSYTFTIAG
MAV_0177|M.avium_104 QGAVVSVAVRP-LGPAGTYTAN-------YRVTSADGHVVAGSWSFRLTV
TH_1515|M.thermoresistible__bu DGPVVSVAVKP-LGPAGTYTAN-------YRATSADGHVVQGSWTFELKV
MSMEG_6436|M.smegmatis_MC2_155 EGTVVSVGVRP-LGPAGTYTVN-------YRATSADGHVVSGSWSFDLTV
MAB_0109c|M.abscessus_ATCC_199 SGAVISVGVKA-GAPAGKYTVN-------YRVISEDGHPVDGSWAFTITG
Mb0461|M.bovis_AF2122/97 LVAALTPAISGLGAVSGLAGLTGLVPQPPVVPAPAPDAVVPTVLPLAGTA
Rv0453|M.tuberculosis_H37Rv LVAALTPAISGLGAVSGLAGLTGLVPQPPVVPAPAPDAVVPTVLPLAGTA
MMAR_1100|M.marinum_M GGAAQCPSQRPETSRDTATVVVSPAWYDDYVLTVGSVNANGEPSAFTLPS
. . .:
Mflv_2807|M.gilvum_PYR-GCK VPEQPSPTTAPARAAPSTAEPSPPAPAATAG--SDTKASVLT--------
Mvan_3714|M.vanbaalenii_PYR-1 VPEQPSPTTAPARAAPSTAEPSPPAPAAKAG--SDTKASVLT--------
MAV_0177|M.avium_104 PGT----GTPGP-------AAAGHAGGG------GGAVPVWP--------
TH_1515|M.thermoresistible__bu AGS----GEPGPPATLPADTADGESDGATDGAATGADLPVWV--------
MSMEG_6436|M.smegmatis_MC2_155 AGP----GTPGP------TVAPAPAPAASE----DDGLPVWP--------
MAB_0109c|M.abscessus_ATCC_199 SGSSAAAGAPAISQQPSGTTSSAPVPSANP---TDGDLPMWP--------
Mb0461|M.bovis_AF2122/97 TPTTAPASAPAAGAAPGPPAGTATATSASVPTSAGGFPPYLVGSGPGIDF
Rv0453|M.tuberculosis_H37Rv TPTTAPASAPAAGAAPGPPAGTATATSASVPTSAGGFPPYLVGSGPGIDF
MMAR_1100|M.marinum_M PWVDVAAGGENVTSLNPVGDGTVNGLDDHGGFRPLSGTSYAAPVVSG---
.
Mflv_2807|M.gilvum_PYR-GCK ---------------AAGAGLALGGVIAFWQSRRHRRKNAAEHPRSEPGR
Mvan_3714|M.vanbaalenii_PYR-1 ---------------AAGAGLALGGLIAFWQSRRHRRKNAAEHPGSEPGS
MAV_0177|M.avium_104 ---------------FVAAAAALIAGGAWWAARRGR--------------
TH_1515|M.thermoresistible__bu ---------------FVLIAAVIVAGGLVWAVRRQQ--------------
MSMEG_6436|M.smegmatis_MC2_155 ---------------FVLAAVVIVGGGAWWALRRRA--------------
MAB_0109c|M.abscessus_ATCC_199 ---------------FVVAVVVSVGAALIWTQRRQS--------------
Mb0461|M.bovis_AF2122/97 DAGTPAGSRRAQPAADNVTAVAAAQVSARHQARRRRRAAAKERGNADEFV
Rv0453|M.tuberculosis_H37Rv DAGTPAGSRRAQPAADNVTAVAAAQVSARHQARRRRRAAAKERGNADEFV
MMAR_1100|M.marinum_M -----LAALIRARFPALTARQVMARIISTAHHPPHGWDPFVGNGTVDVLA
.
Mflv_2807|M.gilvum_PYR-GCK SG-GQNTSPPSDRRD-----------------------------------
Mvan_3714|M.vanbaalenii_PYR-1 SLRGQDTSPPSDRRD-----------------------------------
MAV_0177|M.avium_104 --------------------------------------------------
TH_1515|M.thermoresistible__bu --------------------------------------------------
MSMEG_6436|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0109c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0461|M.bovis_AF2122/97 DMDSGPAIPPSGERDAWASNSGVGGLGFAGTASNETVAAPAGLTTLADDE
Rv0453|M.tuberculosis_H37Rv DMDSGPAIPPSGERDAWASNSGVGGLGFAGTASNETVAAPAGLTTLADDE
MMAR_1100|M.marinum_M AVSSDPAVQPAPAQPGSPTPAAPVTTPPAQPDRRARITALSGSAICLMGL
Mflv_2807|M.gilvum_PYR-GCK ----------------------------
Mvan_3714|M.vanbaalenii_PYR-1 ----------------------------
MAV_0177|M.avium_104 ----------------------------
TH_1515|M.thermoresistible__bu ----------------------------
MSMEG_6436|M.smegmatis_MC2_155 ----------------------------
MAB_0109c|M.abscessus_ATCC_199 ----------------------------
Mb0461|M.bovis_AF2122/97 FQCGPRMPMLPGAWDLGTWDRGD-----
Rv0453|M.tuberculosis_H37Rv FQCGPRMPMLPGAWDLGTWDRGD-----
MMAR_1100|M.marinum_M LAALASRAFGGRSGSRHRRIHRDDVVGD