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M. gilvum PYR-GCK Mflv_2054 (-)

annotation: hemolysin III family channel protein
coordinates: 2131748 - 2132500
length: 250

PLSGGEMPTSLEPWYSADRSQGPEDLPEAVAEGVAQFFGKPRLRGWIHVYSAVIAVICGSALVAVSWSAQ
STRSGIATLIYTLTIVAMFAVSGTYHRVNWTSATARKWMKRADHSMIFLFIAGSYTPFALLALPENDGMV
LLWIVWGGALAGVALKMLWPSSPRWLGVPLYILLGWVAVWFIGPIMHGAGVAAVVLLIVGGALYSIGGVL
YALKWPNPWPTTFGHHEFFHACTAVAAICHYIAMWFAVF*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2054--100% (250)hemolysin III family channel protein
M. gilvum PYR-GCKMflv_1523-1e-7360.61% (198) hemolysin III family channel protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1114c-1e-9870.48% (227) hemolysin-like protein
M. tuberculosis H37RvRv1085c-1e-9870.48% (227) hemolysin-like protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1208c-8e-9266.97% (221) hypothetical protein MAB_1208c
M. marinum MMMAR_4381-4e-9972.73% (220) hemolysin-like protein
M. avium 104MAV_1210-2e-9467.84% (227) channel protein, hemolysin III family protein
M. smegmatis MC2 155MSMEG_5257-1e-12184.62% (234) channel protein, hemolysin III family protein
M. thermoresistible (build 8)TH_2166-1e-10676.99% (226) POSSIBLE HEMOLYSIN-LIKE PROTEIN
M. ulcerans Agy99MUL_0194-5e-9972.27% (220) hemolysin-like protein
M. vanbaalenii PYR-1Mvan_4663-1e-13592.59% (243) hemolysin III family channel protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2054|M.gilvum_PYR-GCK          -MPLSGGEMPTSLEPWYSADRSQG-----PEDLPEAVAEGVAQFFGKPRL
Mvan_4663|M.vanbaalenii_PYR-1       --------MPTTLEPWYTADSPGE-----PEDLPEAVAEGVAQFLGKPRL
MSMEG_5257|M.smegmatis_MC2_155      MTAPIDGSHDRRTAPYRSAAADAAGSQRQAEDLPAAVADGVAQFFGKPRA
TH_2166|M.thermoresistible__bu      --------MTTRLDNTSDFEDPSAR--EHAEDFPEAVVDRVAHAIGKPRA
Mb1114c|M.bovis_AF2122/97           --------MSGQADTATTAEARTP------AHAAHHLVEGVARVLTKPRF
Rv1085c|M.tuberculosis_H37Rv        --------MSGQADTATTAEARTP------AHAAHHLVEGVARVLTKPRF
MMAR_4381|M.marinum_M               --------MSSQASMASTAEPEPQG--LAVPNAAHHLVEGVARALTKPRF
MUL_0194|M.ulcerans_Agy99           --------MSSQASMASTAEPEPQG--LAVPNAAHHLVEGVARALTKPRF
MAV_1210|M.avium_104                --------MSSQTSTAPNPEPDHEA--IVPGNTVEQLVEGAAQVLGKPRM
MAB_1208c|M.abscessus_ATCC_199      --------MQTDESPAPEAPEAPTS---ELSIPMAALVGGIETLPIKPKA
                                                                        :.        **: 

Mflv_2054|M.gilvum_PYR-GCK          RGWIHVYSAVIAVICGSALVAVSWSAQSTRSGIATLIYTLTIVAMFAVSG
Mvan_4663|M.vanbaalenii_PYR-1       RGWIHVYSAVIAVICGVTLVAVSWSLESTRAGIATLIYTLTIVAMFTVSG
MSMEG_5257|M.smegmatis_MC2_155      RGWIHVYSAIVALIAGAALVSVSWSVQSTRAGLATLLYTFTIVAMFTVSG
TH_2166|M.thermoresistible__bu      RGWIHVYAAVISAIAGATLVSVSWAVDSTRAGIATLIYTITSVAMFTVSG
Mb1114c|M.bovis_AF2122/97           RGWIHVYSAGTAVLAGASLVAVSWAVGSAKAGLTTLAYTAATITMFTVSA
Rv1085c|M.tuberculosis_H37Rv        RGWIHVYSAGTAVLAGASLVAVSWAVGSAKAGLTTLAYTAATITMFTVSA
MMAR_4381|M.marinum_M               RGWIHVYSAGTAVLAGASLVAVSWAVGSTEAGLATLAYIAATVVMFTVSA
MUL_0194|M.ulcerans_Agy99           RGWIHVYSAGTAVLAGASLVAVSWAVGSTEAGLATLAYVAATVVMFTVSA
MAV_1210|M.avium_104                RGWIHFYSAWLAVITGATLVSVSWAAASPRAGHSTLIYAAATVALFAVSA
MAB_1208c|M.abscessus_ATCC_199      RGWIHFYACVIAIVTGIVLVSVAWSLRSPKAGLATAIYSLTVLGVFGVSA
                                    *****.*:.  : : *  **:*:*:  *..:* :*  *  : : :* **.

Mflv_2054|M.gilvum_PYR-GCK          TYHRVNWTSATARKWMKRADHSMIFLFIAGSYTPFALLALPENDGMVLLW
Mvan_4663|M.vanbaalenii_PYR-1       VYHRVNWTSVTARKWMKRADHSMIFLFIAGSYTPFALLALPERDGMVLLW
MSMEG_5257|M.smegmatis_MC2_155      VYHRVNWTSVTARKWMKRLDHSMIFLFIAGSYTPFALLALPESKGMVLFW
TH_2166|M.thermoresistible__bu      VYHRYSWRSETARTWMMRADHSMIFIFIAGSYTPFGMLALPEGSGNVLLA
Mb1114c|M.bovis_AF2122/97           TYHRVNWKSATARNWMKRADHSMIFVFIAGSYTPFALLALPAHDGRVVLS
Rv1085c|M.tuberculosis_H37Rv        TYHRVNWKSATARNWMKRADHSMIFVFIAGSYTPFALLALPAHDGRVVLS
MMAR_4381|M.marinum_M               TYHRVNWASATTHKWMKRADHSMIFVFIAGSYTPFALLALPGHDGRVVLS
MUL_0194|M.ulcerans_Agy99           TYHRVNWASATTHKWMKRADHSMIFVFIAGSYTPFALLALPGHDGRVVVS
MAV_1210|M.avium_104                TYHRVKWKTEAARTRMKRLDHSMIFVFIAGSYTPFARLVMPQNTGVVVLC
MAB_1208c|M.abscessus_ATCC_199      AYHRVNWTSPTTRTWMKRLDHSMIFVFIAGSYTPFAMLAMPPSEGNLVLA
                                    .*** .* : :::. * * ******:*********. *.:*   * ::. 

Mflv_2054|M.gilvum_PYR-GCK          IVWGGALAGVALKMLWPSSPRWLGVPLYILLGWVAVWFIGPIMHGAGVAA
Mvan_4663|M.vanbaalenii_PYR-1       IVWAGALAGVALKMLWPSSPRWLGVPLYILLGWVAVWFIGPIAHGAGVAA
MSMEG_5257|M.smegmatis_MC2_155      IVWGGAIAGVLLKMFWPSAPRWLGVPLYILLGWVAAWFIGPIMDGAGVAA
TH_2166|M.thermoresistible__bu      IVWGGALAGVLLKMFWPSAPRWVGVPLYLLLGWVAAWFIGPIANGAGLPA
Mb1114c|M.bovis_AF2122/97           IVWGGAIAGILLKMCWPAAPRSVGVPLYLLLGWVAVWYTATILHNAGVTA
Rv1085c|M.tuberculosis_H37Rv        IVWGGAIAGILLKMCWPAAPRSVGVPLYLLLGWVAVWYTATILHNAGVTA
MMAR_4381|M.marinum_M               IVWGGAIAGILLKMCWPTAPRWVGVPLYLLLGWVAVWYTATILHNAGVTA
MUL_0194|M.ulcerans_Agy99           IVWGGAIAGILLKMCWPTAPRWVGVPLYLLLGWVAVWYTATILHNAGVTA
MAV_1210|M.avium_104                IVWGGALAGIALKVCWPTAPRWLGVPLYLLLGWVAIWYAPTILHQAGVAA
MAB_1208c|M.abscessus_ATCC_199      IVWGGALAGVILKMCWPTAPRWVGVPLYLLLGWVAVGFFPTLLNGAGVAA
                                    ***.**:**: **: **::** :*****:******  :  .: . **:.*

Mflv_2054|M.gilvum_PYR-GCK          VVLLIVGGALYSIGGVLYALKWPNPWPTTFGHHEFFHACTAVAAICHYIA
Mvan_4663|M.vanbaalenii_PYR-1       VVLLIVGGALYSIGGVLYALKWPNPWPTTFGHHEFFHACTAVAAICHYIA
MSMEG_5257|M.smegmatis_MC2_155      VVLLIVGGALYSVGGVLYALKWPNPWPATFGHHEFFHACTAVAAICHYIA
TH_2166|M.thermoresistible__bu      VVLLIVGGVLYSVGGVLYALKWPDPWPETFGYHEFFHACTAVAALCHYIA
Mb1114c|M.bovis_AF2122/97           LVLLFVGGALYSIGGILYAVRWPDPWPTTFGYHEFFHACTAVAAICHYIA
Rv1085c|M.tuberculosis_H37Rv        LVLLFVGGALYSIGGILYAVRWPDPWPTTFGYHEFFHACTAVAAICHYIA
MMAR_4381|M.marinum_M               LVLLFVGGALYSIGGILYAVRWPDPWPSTFGYHEFFHACTAVAAICHYIA
MUL_0194|M.ulcerans_Agy99           LVLLFVGGALYSIGGILYAVRWPDPWPSTFGYHEFFHACTAVAAICHYIA
MAV_1210|M.avium_104                MVLLAVGGVLYSVGGIFYALRWPDPWPSTFGYHEFFHALTAIAAILHYIA
MAB_1208c|M.abscessus_ATCC_199      VVLLIVGGALYSIGAILYAAKWPNPWPLHFGHHEFFHAATVIAATCHYIA
                                    :*** ***.***:*.::** :**:***  **:****** *.:**  ****

Mflv_2054|M.gilvum_PYR-GCK          MWFAVF-----------
Mvan_4663|M.vanbaalenii_PYR-1       MWFAVF-----------
MSMEG_5257|M.smegmatis_MC2_155      MWFAVF-----------
TH_2166|M.thermoresistible__bu      MWFAVF-----------
Mb1114c|M.bovis_AF2122/97           MWFVVF-----------
Rv1085c|M.tuberculosis_H37Rv        MWFVVF-----------
MMAR_4381|M.marinum_M               MWFVVF-----------
MUL_0194|M.ulcerans_Agy99           MWFVVF-----------
MAV_1210|M.avium_104                MWFAVFYTGDHAWLATA
MAB_1208c|M.abscessus_ATCC_199      VWFAVFA----------
                                    :**.**