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VSAVVAVFAGVALVQGAWMSPSERAGWAASVYVAGVVAMFTVSATYHRVEWGSPQAEKWMMRLDHSVIFL FIAASYTPLAVLALPPGVGAEVLTMVWAGALAGVALKMCWPSAPRWVGIPLYLMLGYVAIWFADALLHGA GATVVALLIAGGVLYNLGAILYGVQWPNPWPATFGHHEFFHAFTVAAAACHFAAIWLIVH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1523 | - | - | 100% (200) | hemolysin III family channel protein |
| M. gilvum PYR-GCK | Mflv_2054 | - | 1e-73 | 60.61% (198) | hemolysin III family channel protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1114c | - | 3e-70 | 58.08% (198) | hemolysin-like protein |
| M. tuberculosis H37Rv | Rv1085c | - | 3e-70 | 58.08% (198) | hemolysin-like protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1208c | - | 3e-72 | 60.10% (198) | hypothetical protein MAB_1208c |
| M. marinum M | MMAR_4381 | - | 1e-72 | 59.60% (198) | hemolysin-like protein |
| M. avium 104 | MAV_1210 | - | 4e-68 | 56.57% (198) | channel protein, hemolysin III family protein |
| M. smegmatis MC2 155 | MSMEG_5257 | - | 3e-72 | 60.61% (198) | channel protein, hemolysin III family protein |
| M. thermoresistible (build 8) | TH_2166 | - | 2e-69 | 58.59% (198) | POSSIBLE HEMOLYSIN-LIKE PROTEIN |
| M. ulcerans Agy99 | MUL_0194 | - | 1e-72 | 59.60% (198) | hemolysin-like protein |
| M. vanbaalenii PYR-1 | Mvan_4663 | - | 1e-73 | 61.62% (198) | hemolysin III family channel protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5257|M.smegmatis_MC2_155 MTAPIDGSHDRRTAPYRSAAADAAGSQRQAEDLPAAVADGVAQFFGKPRA
Mvan_4663|M.vanbaalenii_PYR-1 MPTTLEPWYT----------ADSPG---EPEDLPEAVAEGVAQFLGKPRL
TH_2166|M.thermoresistible__bu MTTRLDNTSD----------FEDPSAREHAEDFPEAVVDRVAHAIGKPRA
Mb1114c|M.bovis_AF2122/97 MSGQADTATT----------AEARTP----AHAAHHLVEGVARVLTKPRF
Rv1085c|M.tuberculosis_H37Rv MSGQADTATT----------AEARTP----AHAAHHLVEGVARVLTKPRF
MMAR_4381|M.marinum_M MSSQASMAST----------AEPEPQGLAVPNAAHHLVEGVARALTKPRF
MUL_0194|M.ulcerans_Agy99 MSSQASMAST----------AEPEPQGLAVPNAAHHLVEGVARALTKPRF
MAV_1210|M.avium_104 MSSQTSTAPN----------PEPDHEAIVPGNTVEQLVEGAAQVLGKPRM
MAB_1208c|M.abscessus_ATCC_199 MQTDESPAPE-----------APEAPTSELSIPMAALVGGIETLPIKPKA
Mflv_1523|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5257|M.smegmatis_MC2_155 RGWIHVYSAIVALIAGAALVSVSWSVQSTRAGLATLLYTFTIVAMFTVSG
Mvan_4663|M.vanbaalenii_PYR-1 RGWIHVYSAVIAVICGVTLVAVSWSLESTRAGIATLIYTLTIVAMFTVSG
TH_2166|M.thermoresistible__bu RGWIHVYAAVISAIAGATLVSVSWAVDSTRAGIATLIYTITSVAMFTVSG
Mb1114c|M.bovis_AF2122/97 RGWIHVYSAGTAVLAGASLVAVSWAVGSAKAGLTTLAYTAATITMFTVSA
Rv1085c|M.tuberculosis_H37Rv RGWIHVYSAGTAVLAGASLVAVSWAVGSAKAGLTTLAYTAATITMFTVSA
MMAR_4381|M.marinum_M RGWIHVYSAGTAVLAGASLVAVSWAVGSTEAGLATLAYIAATVVMFTVSA
MUL_0194|M.ulcerans_Agy99 RGWIHVYSAGTAVLAGASLVAVSWAVGSTEAGLATLAYVAATVVMFTVSA
MAV_1210|M.avium_104 RGWIHFYSAWLAVITGATLVSVSWAAASPRAGHSTLIYAAATVALFAVSA
MAB_1208c|M.abscessus_ATCC_199 RGWIHFYACVIAIVTGIVLVSVAWSLRSPKAGLATAIYSLTVLGVFGVSA
Mflv_1523|M.gilvum_PYR-GCK ------MSAVVAVFAGVALVQGAWMSPSERAGWAASVYVAGVVAMFTVSA
:. : . * ** :* * .** :: * : :* **.
MSMEG_5257|M.smegmatis_MC2_155 VYHRVNWTSVTARKWMKRLDHSMIFLFIAGSYTPFALLALPESKGMVLFW
Mvan_4663|M.vanbaalenii_PYR-1 VYHRVNWTSVTARKWMKRADHSMIFLFIAGSYTPFALLALPERDGMVLLW
TH_2166|M.thermoresistible__bu VYHRYSWRSETARTWMMRADHSMIFIFIAGSYTPFGMLALPEGSGNVLLA
Mb1114c|M.bovis_AF2122/97 TYHRVNWKSATARNWMKRADHSMIFVFIAGSYTPFALLALPAHDGRVVLS
Rv1085c|M.tuberculosis_H37Rv TYHRVNWKSATARNWMKRADHSMIFVFIAGSYTPFALLALPAHDGRVVLS
MMAR_4381|M.marinum_M TYHRVNWASATTHKWMKRADHSMIFVFIAGSYTPFALLALPGHDGRVVLS
MUL_0194|M.ulcerans_Agy99 TYHRVNWASATTHKWMKRADHSMIFVFIAGSYTPFALLALPGHDGRVVVS
MAV_1210|M.avium_104 TYHRVKWKTEAARTRMKRLDHSMIFVFIAGSYTPFARLVMPQNTGVVVLC
MAB_1208c|M.abscessus_ATCC_199 AYHRVNWTSPTTRTWMKRLDHSMIFVFIAGSYTPFAMLAMPPSEGNLVLA
Mflv_1523|M.gilvum_PYR-GCK TYHRVEWGSPQAEKWMMRLDHSVIFLFIAASYTPLAVLALPPGVGAEVLT
.*** .* : :.. * * ***:**:***.****:. *.:* * :.
MSMEG_5257|M.smegmatis_MC2_155 IVWGGAIAGVLLKMFWPSAPRWLGVPLYILLGWVAAWFIGPIMDGAGVAA
Mvan_4663|M.vanbaalenii_PYR-1 IVWAGALAGVALKMLWPSSPRWLGVPLYILLGWVAVWFIGPIAHGAGVAA
TH_2166|M.thermoresistible__bu IVWGGALAGVLLKMFWPSAPRWVGVPLYLLLGWVAAWFIGPIANGAGLPA
Mb1114c|M.bovis_AF2122/97 IVWGGAIAGILLKMCWPAAPRSVGVPLYLLLGWVAVWYTATILHNAGVTA
Rv1085c|M.tuberculosis_H37Rv IVWGGAIAGILLKMCWPAAPRSVGVPLYLLLGWVAVWYTATILHNAGVTA
MMAR_4381|M.marinum_M IVWGGAIAGILLKMCWPTAPRWVGVPLYLLLGWVAVWYTATILHNAGVTA
MUL_0194|M.ulcerans_Agy99 IVWGGAIAGILLKMCWPTAPRWVGVPLYLLLGWVAVWYTATILHNAGVTA
MAV_1210|M.avium_104 IVWGGALAGIALKVCWPTAPRWLGVPLYLLLGWVAIWYAPTILHQAGVAA
MAB_1208c|M.abscessus_ATCC_199 IVWGGALAGVILKMCWPTAPRWVGVPLYLLLGWVAVGFFPTLLNGAGVAA
Mflv_1523|M.gilvum_PYR-GCK MVWAGALAGVALKMCWPSAPRWVGIPLYLMLGYVAIWFADALLHGAGATV
:**.**:**: **: **::** :*:***::**:** : .: . ** ..
MSMEG_5257|M.smegmatis_MC2_155 VVLLIVGGALYSVGGVLYALKWPNPWPATFGHHEFFHACTAVAAICHYIA
Mvan_4663|M.vanbaalenii_PYR-1 VVLLIVGGALYSIGGVLYALKWPNPWPTTFGHHEFFHACTAVAAICHYIA
TH_2166|M.thermoresistible__bu VVLLIVGGVLYSVGGVLYALKWPDPWPETFGYHEFFHACTAVAALCHYIA
Mb1114c|M.bovis_AF2122/97 LVLLFVGGALYSIGGILYAVRWPDPWPTTFGYHEFFHACTAVAAICHYIA
Rv1085c|M.tuberculosis_H37Rv LVLLFVGGALYSIGGILYAVRWPDPWPTTFGYHEFFHACTAVAAICHYIA
MMAR_4381|M.marinum_M LVLLFVGGALYSIGGILYAVRWPDPWPSTFGYHEFFHACTAVAAICHYIA
MUL_0194|M.ulcerans_Agy99 LVLLFVGGALYSIGGILYAVRWPDPWPSTFGYHEFFHACTAVAAICHYIA
MAV_1210|M.avium_104 MVLLAVGGVLYSVGGIFYALRWPDPWPSTFGYHEFFHALTAIAAILHYIA
MAB_1208c|M.abscessus_ATCC_199 VVLLIVGGALYSIGAILYAAKWPNPWPLHFGHHEFFHAATVIAATCHYIA
Mflv_1523|M.gilvum_PYR-GCK VALLIAGGVLYNLGAILYGVQWPNPWPATFGHHEFFHAFTVAAAACHFAA
:.** .**.**.:*.::*. :**:*** **:****** *. ** *: *
MSMEG_5257|M.smegmatis_MC2_155 MWFAVF-----------
Mvan_4663|M.vanbaalenii_PYR-1 MWFAVF-----------
TH_2166|M.thermoresistible__bu MWFAVF-----------
Mb1114c|M.bovis_AF2122/97 MWFVVF-----------
Rv1085c|M.tuberculosis_H37Rv MWFVVF-----------
MMAR_4381|M.marinum_M MWFVVF-----------
MUL_0194|M.ulcerans_Agy99 MWFVVF-----------
MAV_1210|M.avium_104 MWFAVFYTGDHAWLATA
MAB_1208c|M.abscessus_ATCC_199 VWFAVFA----------
Mflv_1523|M.gilvum_PYR-GCK IWLIVH-----------
:*: *.