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RTTTGTEHRDAVIVGGGHNGLVAAAYLARAGRRVLVLERLDQVGGAAVSAHPFDGVDARLSRYSYLVSLL PRRIVDDLGARVQLARRRWSSYTPNPADGGRTGLLIGPESTFAAVGAAADEAGFAEFYRRCATVTTRLWP TLTEPLQTRTALRRTVCSAGGEAAWQAMIERPVGEAITDAVADDLVRGVMATDALIGTFADMHDQSLIQN RCLLYHLIGGGNGDWDVPIGGMGAVSGALAAAATGFGAEILTGAEVYAIDADGMVHYRRTDGEYRVSADH VLANVTPAVLAGLMGEEEPAIAPGAQVKVNLMLRRLPRLRDEKVSAEQAFGGTFHINENFGQLRDAYRQA EAGSVPEPVPCEIYCHTLADPSILSESLRVAGAHTLTVFGLHTPHTLAHGQDGGRYRDTLTAAVLDSLDT VLAEPIRDVVWLDAAGRPCIETKTTLDLDATLGMTNGHIFHGALQWPFAEDDEPLSTPAQRWGVDTPHER ILLCGSGSRRGGAVSGIGGHNAAMAVLES*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1732 | - | - | 100% (520) | hypothetical protein Mflv_1732 |
| M. gilvum PYR-GCK | Mflv_1677 | - | 5e-06 | 50.00% (46) | FAD dependent oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3377 | - | 4e-05 | 43.55% (62) | FAD dependent oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0921c | - | 0.0 | 66.28% (519) | oxidoreductase |
| M. tuberculosis H37Rv | Rv0897c | - | 0.0 | 66.28% (519) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0948c | - | 1e-175 | 61.09% (514) | hypothetical protein MAB_0948c |
| M. marinum M | MMAR_4639 | - | 0.0 | 67.84% (513) | oxidoreductase |
| M. avium 104 | MAV_1019 | - | 0.0 | 68.36% (512) | phytoene dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5667 | - | 0.0 | 73.24% (512) | phytoene dehydrogenase |
| M. thermoresistible (build 8) | TH_0456 | - | 0.0 | 71.66% (487) | PROBABLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_0254 | - | 0.0 | 68.23% (513) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5019 | - | 0.0 | 78.39% (509) | hypothetical protein Mvan_5019 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0921c|M.bovis_AF2122/97 --MSDHDRDFDVVVVGGGHNGLVAAAYLARAGLRVRLLERLAQTGGAAVS
Rv0897c|M.tuberculosis_H37Rv --MSDHDRDFDVVVVGGGHNGLVAAAYLARAGLRVRLLERLAQTGGAAVS
MMAR_4639|M.marinum_M ------MKEFDVVVVGGGHNGLVAAAYLARAGLRVRVLERLGHVGGAAVS
MUL_0254|M.ulcerans_Agy99 ------MKEFDVVVVGGGHNGLVAAAYLARAGLRVRVLERLGYVGGAAVS
MAV_1019|M.avium_104 ------------MVIGGGHNGLVAAAYLARAGLRVRLLERLGQVGGAAVS
Mflv_1732|M.gilvum_PYR-GCK MRTTTGTEHRDAVIVGGGHNGLVAAAYLARAGRRVLVLERLDQVGGAAVS
Mvan_5019|M.vanbaalenii_PYR-1 ----MSEGRVDTVIVGGGHNGLVAAAYLAKAGRSVRVLERLGHVGGAAVS
MSMEG_5667|M.smegmatis_MC2_155 ----MTEPQFDAVIVGGGHNGLVAAAYLARAGRRVRVLERLDHVGGAAVS
TH_0456|M.thermoresistible__bu ----------------------------------VLVLERLDHVGGAAVS
MAB_0948c|M.abscessus_ATCC_199 -MGLSESDRYDTVIVGGGHNALTAAAYLARAGQRVMLLERLDVFGGAAIS
* :**** ****:*
Mb0921c|M.bovis_AF2122/97 IQAFDGVEVALSRYSYLVSLLPSRIVADLGAPVRLARRPFSSYTPAPATA
Rv0897c|M.tuberculosis_H37Rv IQAFDGVEVALSRYSYLVSLLPSRIVADLGAPVRLARRPFSSYTPAPATA
MMAR_4639|M.marinum_M IQAFDGVEVRLSRYSYLVSLLPPQIIKDLGAPVRLARRQFSSYTPQPDTH
MUL_0254|M.ulcerans_Agy99 IQAFDGVEVRLSRYSYLVSLLPPQIIKDLGAPVRLARRQFSSYTPQPDTH
MAV_1019|M.avium_104 AHAFDGVGVRVSRYSYLVSLLPPRIIDDLGARVRLARRRFSSYTPDPATG
Mflv_1732|M.gilvum_PYR-GCK AHPFDGVDARLSRYSYLVSLLPRRIVDDLGARVQLARRRWSSYTPNPADG
Mvan_5019|M.vanbaalenii_PYR-1 LYPFDGIDARLSRYSYLVSLLPRRIVDDLGARIRLARRRYSSYTPDPSDG
MSMEG_5667|M.smegmatis_MC2_155 AHAFDGVDARLSRYSYLVSLLPRSIVDDLGARVRLARRRYSSYTPDPATG
TH_0456|M.thermoresistible__bu AHAFDGVDARLSRYSYLVSLLPRRIVDDLGARVRLARRRYSSYTPDPETG
MAB_0948c|M.abscessus_ATCC_199 APAFEGVEARLSRYSYLVSLMPRQIIDDLGLDVRLARRKYASYTPDPMNG
.*:*: . :*********:* *: *** ::**** ::**** *
Mb0921c|M.bovis_AF2122/97 GRSGLLIGPTGEPRAAHLAAIGAAPDAHGFAAFYRRCRLVTARLWPTLIE
Rv0897c|M.tuberculosis_H37Rv GRSGLLIGPTGEPRAAHLAAIGAAPDAHGFAAFYRRCRLVTARLWPTLIE
MMAR_4639|M.marinum_M GRSGLLIGTAGD---DTFAAVGAAGDEPGFAAFYRRCRLVTERLWPTLLE
MUL_0254|M.ulcerans_Agy99 GRSGLLIGTAGD---DTFAAVGAAGDEPGFAAFYRRCRLVTERLWPTLLE
MAV_1019|M.avium_104 GARGLLIGAPGN----PFAAVGAAGDAPGFAAFYRRCRLVTERLWPTLLE
Mflv_1732|M.gilvum_PYR-GCK GRTGLLIGPEST-----FAAVGAAADEAGFAEFYRRCATVTTRLWPTLTE
Mvan_5019|M.vanbaalenii_PYR-1 GRSGLLIGPEST-----FGAVGAAADEAGFGEFYRQCATVTSALWPTLTE
MSMEG_5667|M.smegmatis_MC2_155 GRTGLLVGPEST-----FAAIGAADDAERFAEFYRRWSLVTTRVWPTLLQ
TH_0456|M.thermoresistible__bu GRTGLLIGPETT-----FAAVGAADDEARFADFHRRSRMLTERLWPTMLQ
MAB_0948c|M.abscessus_ATCC_199 GQRGFLAG------------------PNDFAEFGALCDSVTRPMWDSMLQ
* *:* * *. * :* :* :: :
Mb0921c|M.bovis_AF2122/97 PLRTREQARRDIVEYGGHEAAAAWQAMVDEPIGHAIAGAVANDLLRGVIA
Rv0897c|M.tuberculosis_H37Rv PLRTREQARRDIVEYGGHEAAAAWQAMVDEPIGHAIAGAVANDLLRGVIA
MMAR_4639|M.marinum_M PLRTRDQARRTVVDCGDPEALGAWHAMIDEPIGRAITAAVHDDLVRGVIA
MUL_0254|M.ulcerans_Agy99 PLRTRDQARRTVVDYGAPEALGAWHAMIEEPIGRAITAAVHDDLVRGVIA
MAV_1019|M.avium_104 PLRSRRHARRHVVDGGGAGAQAAWRALVEEPIGAAIADAVGNDLVRGVIA
Mflv_1732|M.gilvum_PYR-GCK PLQTRTALRRTVCSA---GGEAAWQAMIERPVGEAITDAVADDLVRGVMA
Mvan_5019|M.vanbaalenii_PYR-1 PLRTRSEAHRAVVGA---GGRDAWQWMIERPLAEAITSAVGDDLVRGVMA
MSMEG_5667|M.smegmatis_MC2_155 PLRTRAQMREHVLAGQGPEAAAAWEDLTTRPIGDVITASVRNDLVRGVMA
TH_0456|M.thermoresistible__bu PLRRRGDLRRQITAG-APDLDAVWRAMVDEPIGAAITAAVRSDLVRGVIA
MAB_0948c|M.abscessus_ATCC_199 PLRRRGAVR-----------TGAWEQLIETPIGEVIRAATPDDVRRGVLL
**: * : .*. : *:. .* :. .*: ***:
Mb0921c|M.bovis_AF2122/97 TDALIGTFARMHEPSLMQNICFLYHLVGGGTGVWHVPIGGMGSVTSALAT
Rv0897c|M.tuberculosis_H37Rv TDALIGTFARMHEPSLMQNICFLYHLVGGGTGVWHVPIGGMGSVTSALAT
MMAR_4639|M.marinum_M TDALIGTFAGLDEPSLAQNICFLYHLLGGGTGDWDVPIGGMGSVTAGLAA
MUL_0254|M.ulcerans_Agy99 TDALIGTFAGLDEPSLTQNICFLYHLLGGGTGDWDVPIGGMGSVTAGLAA
MAV_1019|M.avium_104 TDALIGTFARLDDPSLTQNVCFLYHVLGGGTGDWDVPVGGMGALTTALAT
Mflv_1732|M.gilvum_PYR-GCK TDALIGTFADMHDQSLIQNRCLLYHLIGGGNGDWDVPIGGMGAVSGALAA
Mvan_5019|M.vanbaalenii_PYR-1 TDALIGTFARLDEESLVQNRCFLYHLIGGGTGDWDVPIGGMGAVSEAMAA
MSMEG_5667|M.smegmatis_MC2_155 TDALIGTFAATDDPALIQNVCFLYHLIGGGTGDWDVPIGGMGAVTGALAA
TH_0456|M.thermoresistible__bu TDALIGTFARLDDPSLIQNRCFLYHLIGG---DWAVPVGGMGAVSGALAA
MAB_0948c|M.abscessus_ATCC_199 TDALIGTFASADDLSLQQNICFLYHQMNP----WDVPIGGMGAVTGSLEA
********* .: :* ** *:*** :. * **:****::: .: :
Mb0921c|M.bovis_AF2122/97 AAARHGAEIVTGADVFALDPDGTVRYHSDGSDGAEHLVRGRFVLVGVTPA
Rv0897c|M.tuberculosis_H37Rv AAARHGAEIVTGADVFALDPDGTVRYHSDGSDGAEHLVRGRFVLVGVTPA
MMAR_4639|M.marinum_M AATGYGAEIVTGAEAVAVTPNGDVRYR-AGDD--EHLIRGRFVLAGVTPA
MUL_0254|M.ulcerans_Agy99 AATGYGAEIVTGAEAVAVTPNGDVRYR-AGDD--EHLVRGRFVLAGVTPA
MAV_1019|M.avium_104 AAVRHGAEILTGAEVFAVDPSGEVRYR-SGDD--EHVVRARFVLAGVTPT
Mflv_1732|M.gilvum_PYR-GCK AATGFGAEILTGAEVYAIDADGMVHYRRTDGE---YRVSADHVLANVTPA
Mvan_5019|M.vanbaalenii_PYR-1 AATGFGAEIVTGADVYAIDPEGQVRYRCADDE---HVVAARHILANVTPA
MSMEG_5667|M.smegmatis_MC2_155 SAAGFGAEIVTGAEVYAITPDGEVRYRHGGTA---HRISAHRVLANVTPV
TH_0456|M.thermoresistible__bu AAAGFGAEILTGAQVSAITPDGEVRYHRDGAD---RWAHGEVVLANVAPA
MAB_0948c|M.abscessus_ATCC_199 SARRHGAELLSGAEVLSISPDAEVRYRSDGGE---HTVAGDRVLSGVSPT
:* .***:::**:. :: ... *:*: . . :* .*:*.
Mb0921c|M.bovis_AF2122/97 VLASLLGEPVAALAPGAQVKVNMVVRRLPRLRDDSVTPQQAFAGTFHVNE
Rv0897c|M.tuberculosis_H37Rv VLASLLGEPVAALAPGAQVKVNMVVRRLPRLRDDSVTPQQAFAGTFHVNE
MMAR_4639|M.marinum_M VLAKLLGDTEPTLAPGAQVKVNMVLRRLPRLRDAGVTPEQAFAGTFHANE
MUL_0254|M.ulcerans_Agy99 VLAKLLGDTEPSFAPGAQVKVNMVLRRLPRLRDAVVTPEQAFAGTFHANE
MAV_1019|M.avium_104 VLAGLLGEHPAPAAAGAQVKVNMALRRLPRLADGGVTPEQAFAGTFHVNE
Mflv_1732|M.gilvum_PYR-GCK VLAGLMGEEEPAIAPGAQVKVNLMLRRLPRLRDEKVSAEQAFGGTFHINE
Mvan_5019|M.vanbaalenii_PYR-1 VLARLLGEAEPELAPGAQVKVNLMLTRLPRLRDESVTPEQAFGGTFHINE
MSMEG_5667|M.smegmatis_MC2_155 VLAKLLGEPAPQTAQGSQAKVNLMLRRLPRLRDDTVTAEQAFGGTFHINE
TH_0456|M.thermoresistible__bu ELARLTGSAPPEVTPGAQVKVNLMLRRLPRLRDETVTAEQAFGGTFHVNE
MAB_0948c|M.abscessus_ATCC_199 VLAGLLGETPPAGQPGAQVKVNLLLRRLPRLRDENVTPEQAFGGTFHVNE
** * *. . *:*.***: : ***** * *:.:***.**** **
Mb0921c|M.bovis_AF2122/97 TWSQLDAAYSQAASGRLPDPLPCEAYCHSLTDPSILSARLRDAGAQTLTV
Rv0897c|M.tuberculosis_H37Rv TWSQLDAAYSQAASGRLPDPLPCEAYCHSLTDPSILSARLRDAGAQTLTV
MMAR_4639|M.marinum_M TWTQLEAAHQRAAAGHLPDPLPCEAYCHSLSDPSILSPALRDSGAQTMTV
MUL_0254|M.ulcerans_Agy99 TWTQLEAAHQRAAAGHLPDPLPCEAYCHSLSDPSILSPALRDVGAQTMTV
MAV_1019|M.avium_104 TWTQLDTAYARAAAGQVPNPLPCEAYCHSLADPSILSDDLRAAGAHTMTV
Mflv_1732|M.gilvum_PYR-GCK NFGQLRDAYRQAEAGSVPEPVPCEIYCHTLADPSILSESLRVAGAHTLTV
Mvan_5019|M.vanbaalenii_PYR-1 TYRQLDAAYRQAAAGSVPDPLPCEIYCHTLADPTILSDSLRAAGAHTLTV
MSMEG_5667|M.smegmatis_MC2_155 TLRQLDSAHAAAAGGRVPDPLPCEIYCHSLTDPSILSDDLRASGAQTLTV
TH_0456|M.thermoresistible__bu GFGRLQAAYDEAAAGQVPAPLPCEVYAHSLTDPSILGDGLRAAGAHTMTV
MAB_0948c|M.abscessus_ATCC_199 TYTQLEYAYQQASHGRIPDPLPCEIYCHSLADPSILSPELRASGAHTLTV
:* *: * * :* *:*** *.*:*:**:**. ** **:*:**
Mb0921c|M.bovis_AF2122/97 FGLHTPHSVFG--DTEGLAERLTAAVLASLNSVLAEPIQDVLWTDAQSKP
Rv0897c|M.tuberculosis_H37Rv FGLHTPHSVFG--DTEGLAERLTAAVLASLNSVLAEPIQDVLWTDAQSKP
MMAR_4639|M.marinum_M FGLHTPHSVFGNADPDVLRDQLTAAVLASLNSVLAEPIQDVLLTDADGRP
MUL_0254|M.ulcerans_Agy99 FGLHTPHSVFGNADPDVLRDQLTAAVLASLNSVLAEPIQDVLLTDADGRP
MAV_1019|M.avium_104 FGLHTPHALARGADPDTLRGRLTDRVLASLNSVLAEPIQELLLTDARGRP
Mflv_1732|M.gilvum_PYR-GCK FGLHTPHTLAHGQDGGRYRDTLTAAVLDSLDTVLAEPIRDVVWLDAAGRP
Mvan_5019|M.vanbaalenii_PYR-1 FGLHTPHSLADSATPDRLRDTLTSAVLTSLNSVLAEPIQDVIMQDSSGRL
MSMEG_5667|M.smegmatis_MC2_155 FGLHTPHSLAAN-DPDRMRDRLTSAVLNSLNSVLAEPIQDVLMEDSAGRL
TH_0456|M.thermoresistible__bu FGLHTPHRLAAA-DPDRVRDRLTSAVLTSLNSVLAEPIQDVIAEDAAGRL
MAB_0948c|M.abscessus_ATCC_199 FGLHTPHGLGAS------AEQLQQAVLASLSSVLAEPITDVVATDTHGRP
******* : * ** **.:****** ::: *: .:
Mb0921c|M.bovis_AF2122/97 CIETTTTLDLQRTLGMTGGNIFHGALSWPFADNDDPLDTPARQWGVATDH
Rv0897c|M.tuberculosis_H37Rv CIETTTTLDLQRTLGMTGGNIFHGALSWPFADNDDPLDTPARQWGVATDH
MMAR_4639|M.marinum_M CIETTTTADLQHTLHMTAGNIFHGALSWPFAENDDTLATPAQQWGVATDH
MUL_0254|M.ulcerans_Agy99 CIETTTTADLQHTLHMTAGNIFHGALSWPFAENDDTLATPAQQWGVATNH
MAV_1019|M.avium_104 CIETTTTADLERTLNMSGGNIFHGGLDWPFADDDDPLDTPGRQWGVATAH
Mflv_1732|M.gilvum_PYR-GCK CIETKTTLDLDATLGMTNGHIFHGALQWPFAEDDEPLSTPAQRWGVDTPH
Mvan_5019|M.vanbaalenii_PYR-1 CIEAKTTSDLDDALGMTDGNIFHGALSWPFVEDDEPLATPAQRWGVATAH
MSMEG_5667|M.smegmatis_MC2_155 CIEAKTTVDLERSLGMTAGNIFHDALRWPFVDDDEPLDTPAQRWGVATGH
TH_0456|M.thermoresistible__bu CIETKTTADLEHSLHMTAGNIFHGALRWPFAEDDDPLDTPAQRWGVATGH
MAB_0948c|M.abscessus_ATCC_199 CIETKTTIDLESALGMTAGNIFHGGLQWPFAEDDDPLETAAQRWGVATNH
***:.** **: :* *: *:***..* ***.::*:.* *..::*** * *
Mb0921c|M.bovis_AF2122/97 ERIMLCGSGARRGGAVSGIGGHNAAMAVLACLASRRKSP
Rv0897c|M.tuberculosis_H37Rv ERIMLCGSGARRGGAVSGIGGHNAAMAVLACLASRRKSP
MMAR_4639|M.marinum_M DRIMLCGSGARRGGAVSGIGGHNAAMAVLAYLRQDR---
MUL_0254|M.ulcerans_Agy99 DRIMLCGSGARRGGAVSGIGGHNAAMAVLAYLRQDR---
MAV_1019|M.avium_104 ERIMLCGSGARRGGAVSGIGGHNAAMAVLSSLSSR----
Mflv_1732|M.gilvum_PYR-GCK ERILLCGSGSRRGGAVSGIGGHNAAMAVLES--------
Mvan_5019|M.vanbaalenii_PYR-1 DRILLCGSGSRRGGAVSGIGGHNAAMAVLER--------
MSMEG_5667|M.smegmatis_MC2_155 ERILLCGSGSRRGGAVSGVGGHNAAMAVLERV-------
TH_0456|M.thermoresistible__bu DRILLCGSGSRRGGGVSGIGGHNAAMAVLQR--------
MAB_0948c|M.abscessus_ATCC_199 DRILLCGSGSRRGGGVSGLGGYHAARAVLETH-------
:**:*****:****.***:**::** ***