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VTMDELRRKGLEKMNEVYGWEMPNIEGDPYFDLTVDHLFGTIWTREGLSMRDKRLLTLAAVTAVGNSDLA EIQVNAALHNEEFTAEELKEVALFLTHYLGFPLGSKLDGAVSKVIRNRKKAADKGSGEDRKANVNAAVKM HSGKTLDDE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1603 | - | - | 100% (149) | carboxymuconolactone decarboxylase |
| M. gilvum PYR-GCK | Mflv_1906 | - | 3e-08 | 34.18% (79) | carboxymuconolactone decarboxylase |
| M. gilvum PYR-GCK | Mflv_0527 | - | 5e-08 | 30.56% (108) | 4-carboxymuconolactone decarboxylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0794 | - | 1e-47 | 60.14% (143) | 4-carboxymuconolactone decarboxylase |
| M. tuberculosis H37Rv | Rv0771 | - | 1e-47 | 60.14% (143) | 4-carboxymuconolactone decarboxylase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1221 | - | 3e-37 | 57.03% (128) | 4-carboxymuconolactone decarboxylase |
| M. marinum M | MMAR_4925 | - | 9e-62 | 78.72% (141) | 4-carboxymuconolactone decarboxylase |
| M. avium 104 | MAV_0716 | pcaC | 5e-62 | 78.01% (141) | hypothetical protein MAV_0716 |
| M. smegmatis MC2 155 | MSMEG_5856 | pcaC | 2e-73 | 88.74% (151) | hypothetical protein MSMEG_5856 |
| M. thermoresistible (build 8) | TH_1260 | - | 8e-70 | 83.67% (147) | POSSIBLE 4-CARBOXYMUCONOLACTONE DECARBOXYLASE (CMD) |
| M. ulcerans Agy99 | MUL_0480 | - | 2e-61 | 76.55% (145) | 4-carboxymuconolactone decarboxylase |
| M. vanbaalenii PYR-1 | Mvan_5154 | - | 3e-66 | 76.51% (149) | carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0794|M.bovis_AF2122/97 ---------MMDELRRTGLDKMNEVYAWDMPDMPG-EFFALTVDHLFGRI
Rv0771|M.tuberculosis_H37Rv ---------MMDELRRTGLDKMNEVYAWDMPDMPG-EFFALTVDHLFGRI
Mflv_1603|M.gilvum_PYR-GCK --------MTMDELRRKGLEKMNEVYGWEMPNIEGDPYFDLTVDHLFGTI
MSMEG_5856|M.smegmatis_MC2_155 ----------MDELRRKGLEKMNEVYGWEMPNIEGDPYFDLTVDHLFGTI
TH_1260|M.thermoresistible__bu ----------MDELRRRGLEKMNEVYGWEMPNIEGDPYFDLTVDHLFGTI
Mvan_5154|M.vanbaalenii_PYR-1 --------MSTDELRRKGLEKMNEVYGWEMPDVQGDPYYDLTVEHLFGSI
MMAR_4925|M.marinum_M ----------MDELRRKGLDKMNEVYGWEMPNIEGDAYFDLTVDHLFGTI
MUL_0480|M.ulcerans_Agy99 ----------MDELRRKGLDKMNEVYGWEMPNIEGDAYFDLTVDHLFGTI
MAV_0716|M.avium_104 ---------MMDERRRKGLEKMNEVYGWEMPNVEGDAYFDLTVDHLFGSI
MAB_1221|M.abscessus_ATCC_1997 MVCHTRKGQVMDELRRQGLDKMKEVYGWDMPDIPG-DYFKYTIDHLFGTI
** ** **:**:***.*:**:: * :: *::**** *
Mb0794|M.bovis_AF2122/97 WTRPGLSMRDRRMAVIAVLTAQGQSDLLEVQVNAVLHNDELTIDELRELA
Rv0771|M.tuberculosis_H37Rv WTRPGLSMRDRRMAVIAVLTAQGQSDLLEVQVNAVLHNDELTIDELRELA
Mflv_1603|M.gilvum_PYR-GCK WTREGLSMRDKRLLTLAAVTAVGNSDLAEIQVNAALHNEEFTAEELKEVA
MSMEG_5856|M.smegmatis_MC2_155 WTREGLSMREKRLLTLASVTAVGNSDLAEIQVNAALHNEEFTVDELKEVA
TH_1260|M.thermoresistible__bu WTRPGLSMRDKRIMTLTAVTAVGNSDLAEIQANAALANGELTEDELKEMA
Mvan_5154|M.vanbaalenii_PYR-1 WTRPGLSMRDKRMMTLTVVTALGNSDLAEIQVNAALHNEELTEHELKEMA
MMAR_4925|M.marinum_M WTRPGLSMRDRRLMTLTAVTAIGNRDLAEIQINAALLNGELTEAELKEMA
MUL_0480|M.ulcerans_Agy99 WTRPGLSMRDRRLMTLTAVTAIGNRDLAEIQINAAPLNGELTEAELKEMA
MAV_0716|M.avium_104 WTRPGLSMRDKRIMTLTAVTAIGNRDLAEIQINAALLNGELTETELKEMA
MAB_1221|M.abscessus_ATCC_1997 WTRPELSMRDRRLLLLGAVSALGLDEILEIQTSAALKNGELTEAELREVA
*** ****::*: : ::* * :: *:* .*. * *:* **:*:*
Mb0794|M.bovis_AF2122/97 VFITHYVGFPLGSRLNSAIERVAAKRKQAAENGSLPD----TKANVAEVL
Rv0771|M.tuberculosis_H37Rv VFITHYVGFPLGSRLNSAIERVAAKRKQAAENGSLPD----TKANVAEVL
Mflv_1603|M.gilvum_PYR-GCK LFLTHYLGFPLGSKLDGAVSKVIRNRKKAADKGSGED----RKANVNAAV
MSMEG_5856|M.smegmatis_MC2_155 VFLTHYLGFPLGSKLDGAVSKVARNRKKAAEKGEREDTAEKRRANVNAAV
TH_1260|M.thermoresistible__bu VFLTHYLGFPLGSKLDGAVSKVIKNRRKAAAEGKGED----RKANVDAAV
Mvan_5154|M.vanbaalenii_PYR-1 VFLTHYLGFPLGSKLDGVVSKVAKQRKKAAERGEGEN----KKANVNAAV
MMAR_4925|M.marinum_M VFLTHYLGFPLGSGLNGAVDTVVARRKKAAAKGAGED----KKGNVDDAL
MUL_0480|M.ulcerans_Agy99 VFLTHYLGFPLGSGLNGAVDTVVARRKKAAAKGAGED----KKGNVDDAL
MAV_0716|M.avium_104 VFLTHYLGFPLGSALNGAVDAVVAKRRKAAAKGAGED----KKANVDAAL
MAB_1221|M.abscessus_ATCC_1997 IFITHYVGWPLGQRVNKHVEMAVAKQNEARRTKESSD---------D---
:*:***:*:***. :: :. . .:.:* :
Mb0794|M.bovis_AF2122/97 AKESGKSS------
Rv0771|M.tuberculosis_H37Rv AKESGKSS------
Mflv_1603|M.gilvum_PYR-GCK KMHSGKTLDDE---
MSMEG_5856|M.smegmatis_MC2_155 KMHSGSKLDDK---
TH_1260|M.thermoresistible__bu RMHSGETIHDQHDQ
Mvan_5154|M.vanbaalenii_PYR-1 QMHSGGKVHDDHDQ
MMAR_4925|M.marinum_M KMHSGGKPD-----
MUL_0480|M.ulcerans_Agy99 KMHSGSKPD-----
MAV_0716|M.avium_104 KMHSGGERG-----
MAB_1221|M.abscessus_ATCC_1997 --------------