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MRTELCDRFGIEYPIFVFTPSEKVAAAVTKAGGLGVLGCVRFNDADDLENVLQWMDANTDGKPYGVDIVM PAKVPTEGTSVDINKLIPAEHREFVDKTLADLGVPPLPEDEERSEGVLGWLHSVARSHVEVALKHPIKLI ANALGSPPKDVIDQVHEAGVPVAALAGSPKHALRHVENGVDIVVAQGHEAGGHTGEIGSMVLWPEIVDAL DGRAPVLAAGGIGTGRQVAAALALGAQGVWMGSAFLTSAEYDLGVRLESGRSVIQEAMLKATSADTVRRR IYTGKPARLLKSRWTDAWDAEGAPEPLPMPLQNILVSEAHQRMSESSDPTTVAMPVGQIVGRMNEIRPVA DIIAELVSGFDEASKRLDAIRDN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1544 | - | - | 100% (373) | 2-nitropropane dioxygenase, NPD |
| M. gilvum PYR-GCK | Mflv_3286 | - | 4e-90 | 46.75% (385) | 2-nitropropane dioxygenase, NPD |
| M. gilvum PYR-GCK | Mflv_0037 | - | 5e-74 | 40.79% (380) | 2-nitropropane dioxygenase, NPD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1927c | - | 9e-90 | 46.34% (382) | hypothetical protein Mb1927c |
| M. tuberculosis H37Rv | Rv1894c | - | 9e-90 | 46.34% (382) | hypothetical protein Rv1894c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4162c | - | 1e-171 | 78.71% (371) | putative 2-nitropropane dioxygenase |
| M. marinum M | MMAR_2787 | - | 2e-86 | 46.32% (380) | hypothetical protein MMAR_2787 |
| M. avium 104 | MAV_2807 | - | 3e-93 | 48.44% (384) | oxidoreductase, 2-nitropropane dioxygenase family protein |
| M. smegmatis MC2 155 | MSMEG_5913 | - | 0.0 | 88.44% (372) | dioxygenase |
| M. thermoresistible (build 8) | TH_1822 | - | 0.0 | 85.22% (372) | dioxygenase |
| M. ulcerans Agy99 | MUL_1143 | - | 2e-87 | 46.84% (380) | hypothetical protein MUL_1143 |
| M. vanbaalenii PYR-1 | Mvan_5214 | - | 0.0 | 94.91% (373) | 2-nitropropane dioxygenase, NPD |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1927c|M.bovis_AF2122/97 MHTAICDELGIEFPIFAFTHCRDVVVAVSKAGGFGVLGAVGFT-PEQLEI
Rv1894c|M.tuberculosis_H37Rv MHTAICDELGIEFPIFAFTHCRDVVVAVSKAGGFGVLGAVGFT-PEQLEI
MMAR_2787|M.marinum_M MHTAICDELGIEFPIFAFTHCRDVVVAVSKAGGFGVLGAVGFT-PEQLEI
MUL_1143|M.ulcerans_Agy99 MHTAICDELGIEFPIFAFTHCRDVVLAVSKAGGFGVLGAVGFT-PEQLEI
MAV_2807|M.avium_104 MHTAICDELGIEFPIFAFTHCRDVVVAVSKAGGFGVLGAVGFT-PEQLEI
Mflv_1544|M.gilvum_PYR-GCK MRTELCDRFGIEYPIFVFTPSEKVAAAVTKAGGLGVLGCVRFNDADDLEN
Mvan_5214|M.vanbaalenii_PYR-1 MKTELCDRFGIEYPLFVFTPSEKVAAAVSKAGGLGVLGCVRFNDADDLEN
MSMEG_5913|M.smegmatis_MC2_155 MKTELCERFGIEYPIFVFTPSEKVAAAVSKAGGLGVLGCVRFNDADDLED
TH_1822|M.thermoresistible__bu MRTELCERFGIRYPIFVFTPSEKVAAAVSRAGGLGVLGCVRFNDPDDLEN
MAB_4162c|M.abscessus_ATCC_199 MRTDLCERFGIRYPIFGFTPSEKVAAAISRAGGMGVLGCVRFNDPDELDA
*:* :*:.:**.:*:* ** ...*. *:::***:****.* *. .::*:
Mb1927c|M.bovis_AF2122/97 ELNWIDEHIGDHPYGVDIVIPNKYEGMDSQLSADELAKTLRSMVPQEHLD
Rv1894c|M.tuberculosis_H37Rv ELNWIDEHIGDHPYGVDIVIPNKYEGMDSQLSADELAKTLRSMVPQEHLD
MMAR_2787|M.marinum_M ELTWIDEHIGDHPYGVDIVIPNKYEGMDSHLSAEELANTLRSMVPQQHLD
MUL_1143|M.ulcerans_Agy99 ELNWIDEHIGDHPYGVDIVIPNKYEGMDSHLSAEELANTLRSMVPQQHLD
MAV_2807|M.avium_104 ELKWIDENIGDHPYGVDIVIPNKYEGMDSHLSAEELAETLRKMVPQEHLD
Mflv_1544|M.gilvum_PYR-GCK VLQWMDANTDGKPYGVDIVMP-------AKVPTEGTSVDINKLIPAEHRE
Mvan_5214|M.vanbaalenii_PYR-1 VLQWMDANTDGKPYGVDIVMP-------AKVPTEGTSVDINKLIPAEHRE
MSMEG_5913|M.smegmatis_MC2_155 VLQWMDANTDGKPYGVDVVMP-------AKVPTEGTAVDINKLIPQGHRD
TH_1822|M.thermoresistible__bu VLCWMDDNTDGLPYGVDVVMP-------AKVPTEGSAVDIDKLIPQGHRD
MAB_4162c|M.abscessus_ATCC_199 VLNWMDENTDGKPYGVDIVMP-------AKVPAEGTAVDIDKLIPQGHKD
* *:* : .. *****:*:* :::.:: : : .::* * :
Mb1927c|M.bovis_AF2122/97 FARKILADHGVP-VEDADEDSLQLLGWTEATATPQVDAALKHPKMTMVAN
Rv1894c|M.tuberculosis_H37Rv FARKILADHGVP-VEDADEDSLQLLGWTEATATPQVDAALKHPKMTMVAN
MMAR_2787|M.marinum_M FARKILADHGVP-IEDADEDSLQLLGWTEATATPQVEVALEHSKVTMIAN
MUL_1143|M.ulcerans_Agy99 FARKILADHGVP-IEDADEDSLQLLGWTEATATPQVEVALKHSKVTMIAN
MAV_2807|M.avium_104 FGKKILADHGVP-IEDSDSDSLQLLGWTEATATPQVEVALKHPKVKMIAN
Mflv_1544|M.gilvum_PYR-GCK FVDKTLADLGVPPLPEDEERSEGVLGWLHSVARSHVEVALKHP-IKLIAN
Mvan_5214|M.vanbaalenii_PYR-1 FVDKTLADLGVPPLPADEERSEGVLGWLHSVARSHVEVALKHP-IKLIAN
MSMEG_5913|M.smegmatis_MC2_155 FVAKTLADLGVPPLPEDGERNEGVLGWLHSVARSHVEVALKHP-IKLIAN
TH_1822|M.thermoresistible__bu FVNKTLTELGVPPLSEDQQRNEGVLGWLHSVARSHVDVALKHP-IKLIAN
MAB_4162c|M.abscessus_ATCC_199 FVEKTLADLGVPPLPGERE-SAGVLGWLHSVARSHVEVALKHP-IKLIAN
* * *:: *** : . . :*** .:.* .:*:.**:*. :.::**
Mb1927c|M.bovis_AF2122/97 ALGTPPADMIKHIHDSGRKVAALCGSPSQARKHADAGVDIIIAQGGEAGG
Rv1894c|M.tuberculosis_H37Rv ALGTPPADMIKHIHDSGRKVAALCGSPSQARKHADAGVDIIIAQGGEAGG
MMAR_2787|M.marinum_M ALGTPPAEMIAHIHEQGRKVAALCGSPSQARKHANAGVDIIIAQGGEAGG
MUL_1143|M.ulcerans_Agy99 ALGTPPAEMIAHIHERGRKVAALCGSPSQARKHANAGVDIIIAQGGEAGG
MAV_2807|M.avium_104 ALGTPPADMIKHIHDAGLKVAALCGSPSQARKHADAGVDIIIAQGGEAGG
Mflv_1544|M.gilvum_PYR-GCK ALGSPPKDVIDQVHEAGVPVAALAGSPKHALRHVENGVDIVVAQGHEAGG
Mvan_5214|M.vanbaalenii_PYR-1 ALGSPPKDVIDQAHQAGVPVAALAGSAKHALRHVDNGVDIVVAQGHEAGG
MSMEG_5913|M.smegmatis_MC2_155 ALGSPPKDVIDQAHAAGVPVAALAGSAKHALRHVENGVDIVVAQGHEAGG
TH_1822|M.thermoresistible__bu ALGSPPTDVIERVHKAGVPVAALAGSAKHAQRHVDNGVDIVVAQGHEAGG
MAB_4162c|M.abscessus_ATCC_199 ALGSPPKDVIDQAHEHGVPVAALAGKAEHARRHVENGVDIVVAQGYEAGG
***:** ::* : * * ****.*...:* :*.: ****::*** ****
Mb1927c|M.bovis_AF2122/97 HCGEVGSIVLWPQVVKEVAP-VPVLAAGGIGSGQQIAAALALGTQGAWTG
Rv1894c|M.tuberculosis_H37Rv HCGEVGSIVLWPQVVKEVAP-VPVLAAGGIGSGQQIAAALALGTQGAWTG
MMAR_2787|M.marinum_M HCGEVGSIVLWPQVVKEVAP-VPVLAAGGIGSGQQIAAALVLGCQGAWTG
MUL_1143|M.ulcerans_Agy99 HCGEVGSIVLWPQVVKEVAP-VPVLAAGGIGSGQQIAAALALGCQGAWTG
MAV_2807|M.avium_104 HCGEVGSIVLWPQVVKEVAP-LPVLAAGGIGSGQQIAAALALGAQGAWTG
Mflv_1544|M.gilvum_PYR-GCK HTGEIGSMVLWPEIVDALDGRAPVLAAGGIGTGRQVAAALALGAQGVWMG
Mvan_5214|M.vanbaalenii_PYR-1 HTGEIGSMVLWPEIVDAIEGRAPVLAAGGIGTGRQVAAALALGAQGVWMG
MSMEG_5913|M.smegmatis_MC2_155 HTGEIGSMVLWPEIVDALDGKAPVLAAGGIGTGRQVAAALALGASGVWMG
TH_1822|M.thermoresistible__bu HTGEIGSVVLWPEIVDAVGDQVPVLAAGGIGTGRQVAAALALGAQGVWMG
MAB_4162c|M.abscessus_ATCC_199 HTGDVASMVLWPEIVDALDGSAPVLAAGGIGSGRQAAAALALGASGVWTG
* *::.*:****::*. : *********:*:* ****.** .*.* *
Mb1927c|M.bovis_AF2122/97 SQWLMVEE-------AANTAVQQAAYVKATSRDTVRSRSFTGKPARMLRN
Rv1894c|M.tuberculosis_H37Rv SQWLMVEE-------AANTAVQQAAYVKATSRDTVRSRSFTGKPARMLRN
MMAR_2787|M.marinum_M SQWLMVEE-------ASNTPVQQAAYAKASSRDTVRSRSFTGKPARMLRN
MUL_1143|M.ulcerans_Agy99 SQWLMVEE-------ASNTPVQQAAYAKASSRDTVRSRSFTGKPARMLRN
MAV_2807|M.avium_104 SQWLMVEE-------SSNTPVQQAAYAKAGSRDTVRSRSFTGKPARMLRN
Mflv_1544|M.gilvum_PYR-GCK SAFLTSAEYDLGVRLESGRSVIQEAMLKATSADTVRRRIYTGKPARLLKS
Mvan_5214|M.vanbaalenii_PYR-1 SAFLTSAEYDLGVRLPSGRSVVQEAMLNATSADTVRRRIYTGKPARLLKS
MSMEG_5913|M.smegmatis_MC2_155 SAFLTSAEYDLGHRKPSGVSTIQEALLRAGTADTVRRKIYTGKPARLLKT
TH_1822|M.thermoresistible__bu SAFLTSAEYDLGVRRESGISTIQQALLDATSADTVRRRIYTGKPARLLKS
MAB_4162c|M.abscessus_ATCC_199 SIWLTAAEYDLGTVTAGGDSVVQQALLKATSGDTVRTRIYTGKPARLLKT
* :* * .. .. * * * : **** : :******:*:.
Mb1927c|M.bovis_AF2122/97 DWTEAWEQPESPKPLGMPLQYMVSGMAVKATHKYPNETVDVAFNPVGQVV
Rv1894c|M.tuberculosis_H37Rv DWTEAWEQPESPKPLGMPLQYMVSGMAVKATHKYPNETVDVAFNPVGQVV
MMAR_2787|M.marinum_M DWTEAWEQADNPKPLGMPLQYMVSGMAVRATNKHPNETVDVAFNPVGQVV
MUL_1143|M.ulcerans_Agy99 DWTEAWEQADNPKPLGMPLQYMVSGMAVRATNKYPNETVDVAFNPVGQVV
MAV_2807|M.avium_104 DWTEAWEAPGNPKPLGMPLQYMVSGMAVRATNKYPNESVDVAFNPVGQVV
Mflv_1544|M.gilvum_PYR-GCK RWTDAWDAEGAPEPLPMPLQNILVSEAHQRMSES-SDPTTVAM-PVGQIV
Mvan_5214|M.vanbaalenii_PYR-1 RWTDAWDADGAPEPLPMPLQNILVSEAHQRMSEN-SDPTAVAM-PVGQIV
MSMEG_5913|M.smegmatis_MC2_155 KWTDAWDAPEAPEPLPMPLQNILVSEAHQRMNES-DNPDTVAM-PVGQIV
TH_1822|M.thermoresistible__bu RWTDAWDAPDAPEPLPMPLQNILVSEAHQRMNYS-TDPTTVAM-PVGQIV
MAB_4162c|M.abscessus_ATCC_199 KWTQAWDAEDAPTPLPMPLQNILVSEAHERMNRA-HDPETVCF-PAGQIV
**:**: * ** **** :: . * . :. *.: *.**:*
Mb1927c|M.bovis_AF2122/97 GQFTKVEKTATVIERWVQEYLEATARLDALNAAASV
Rv1894c|M.tuberculosis_H37Rv GQFTKVEKTATVIERWVQEYLEATARLDALNAAASV
MMAR_2787|M.marinum_M GQFTKVEKAATVIERWVQEYLEATNRLDELNAAAV-
MUL_1143|M.ulcerans_Agy99 GQFTKVEKAATVIERWVQEYLEATNRLDELNAAAV-
MAV_2807|M.avium_104 GQFTKVEKTATVIERWVQEYLEATNRLDELNEAASV
Mflv_1544|M.gilvum_PYR-GCK GRMNEIRPVADIIAELVSGFDEASKRLDAIRDN---
Mvan_5214|M.vanbaalenii_PYR-1 GRMNEIRPVADIIAELVSGFEEATRRLDAIRDN---
MSMEG_5913|M.smegmatis_MC2_155 GRMNQIRPVADIIAELVEGFEKATNRLDTVRDA---
TH_1822|M.thermoresistible__bu GRMNEIRPVGDIIADLVAEFEEATRRLDTIRDG---
MAB_4162c|M.abscessus_ATCC_199 GRMNEIRPTAEIVADLVSGFEAAVDRLDEIRG----
*::.::. .. :: * : * *** :.