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MPPPVRTPRRSWIDAGLALLAQEGPDAVRVEVLAQRLGVTRGGFYRQFEGRSDLVTAMLDEWEQRSIDEV RARVEAEGGDVQSRVTRAGALTFSDELVPLDLAVRDWARRDSDVAARLRRVDTRRIGFLRELLGAVCEDA DEVEARALLAFSLAIGTHVIAADHPGPRQRVVRDATRLILAGVTPV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1468 | - | - | 100% (186) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4460 | - | 6e-17 | 32.10% (162) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0745 | - | 4e-07 | 26.00% (150) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3081 | - | 7e-05 | 35.19% (54) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3055 | - | 7e-05 | 35.19% (54) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3078 | - | 1e-09 | 27.81% (151) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3423 | - | 7e-17 | 34.25% (146) | putative transcriptional regulatory protein |
| M. avium 104 | MAV_2167 | - | 2e-12 | 29.08% (141) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6293 | - | 4e-13 | 29.56% (159) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0904 | - | 4e-17 | 32.72% (162) | transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_2701 | - | 8e-17 | 33.78% (148) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5303 | - | 4e-76 | 73.80% (187) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1468|M.gilvum_PYR-GCK --------------------MPPPVRTPRRSWIDAGLALLAQEGPDAVRV
Mvan_5303|M.vanbaalenii_PYR-1 --------------------MPPPVRTTRDTWIEAGLALLAADGPDAVRV
MAV_2167|M.avium_104 ----------------------------------MGYTVLAEEGVRALKV
MSMEG_6293|M.smegmatis_MC2_155 -------------MAREPRRA--PGTLTADDWLQAGYELLASDGMRALKI
TH_0904|M.thermoresistible__bu -----------MTRPTDPRKPQVTARLSEEDWIQAGFAILAEEGIKALKL
MMAR_3423|M.marinum_M ---------------MAGRGTSGNRRLGVDDWVQAGFEILAEEGLSSLKL
MUL_2701|M.ulcerans_Agy99 ---------------MAGRSTSGNRRLGVDDWVQAGFEILAEEGLISLKL
Mb3081|M.bovis_AF2122/97 MSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITM
Rv3055|M.tuberculosis_H37Rv MSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITM
MAB_3078|M.abscessus_ATCC_1997 ----------------------MTEKVSRDDYFTAAFELLAAGGKSALTT
. ::* * ::
Mflv_1468|M.gilvum_PYR-GCK EVLAQRLGVTRGGFYRQFEGRSDLVTAMLDEWEQRSIDEVRARVEAEGGD
Mvan_5303|M.vanbaalenii_PYR-1 EVLAQRLGVTRGGFYRQFGGRRELIDAMLDTWERRSIDEVQARVESEGGD
MAV_2167|M.avium_104 ERLCQQAGVTRGSFYWHFEDIDNYRAALVESWNKFLERDRQALAELDSLP
MSMEG_6293|M.smegmatis_MC2_155 ERLCEQVGATRGSFYWHFTDMKAYRAALVASWNTFLENDRRSLAEMEDLP
TH_0904|M.thermoresistible__bu DRLCARLAVTKGSFYWHFESMAGFRRRLVESWAELRDRDRRDFDALGALP
MMAR_3423|M.marinum_M DQLCARLGVTKGSFYWHFADMEGYRHALVEAWAQFRDEDRDEIEGLREVE
MUL_2701|M.ulcerans_Agy99 DQLCARLGVTKGSFYWHFADMEGYRHALVEAWAQFRDEDRDEIEGLSEVE
Mb3081|M.bovis_AF2122/97 DDVAAAAGVGKGTLFRRFGSRAGLMMVLLDEDER--ASQQAFLFGPPPLG
Rv3055|M.tuberculosis_H37Rv DDVAAAAGVGKGTLFRRFGSRAGLMMVLLDEDER--ASQQAFLFGPPPLG
MAB_3078|M.abscessus_ATCC_1997 TAVCRRIGMTTGSLYHHFGSGAAFYRAVIDYWENDVTVAQRRRVD-AVAD
:. . * :: :* . ::
Mflv_1468|M.gilvum_PYR-GCK VQSRVTRAGALTFSDELVPLDLAVRDWARRDSDVAARLRRVDTRRIGFLR
Mvan_5303|M.vanbaalenii_PYR-1 ARSKVRRAGMLTFSAELLPLDLAVRDWARRDGEVAARLRRVDNRRMDYLR
MAV_2167|M.avium_104 PRERLSAMMGTLVSPQYWMLERAMREWARLDPVAAENIRAADRHLLRTVT
MSMEG_6293|M.smegmatis_MC2_155 PRERLSKMIEALMSPQHWMLERAMREWARTDEIAAANVRAADHRVRMAVI
TH_0904|M.thermoresistible__bu PRERLSRMMTALTSPRHWMLERAMREWARTDSAAAASVRTADRRVLDAVR
MMAR_3423|M.marinum_M PRERLALMMALLARPRLWKLERAMREWARSDKTVAAAVLSADRRMVRAVQ
MUL_2701|M.ulcerans_Agy99 PRERLALMMALLARPRLWKLERAMREWARSDKTVAAAVLSADRRMVRAVQ
Mb3081|M.bovis_AF2122/97 PDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAALSVLRTHLR
Rv3055|M.tuberculosis_H37Rv PDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAALSVLRTHLR
MAB_3078|M.abscessus_ATCC_1997 PRERLATLEQAAR-EADHEVEKAIRSWAMADRYVAAAQQRVDQVRHEHLT
:. : : : . :
Mflv_1468|M.gilvum_PYR-GCK ELLGAVCEDADEVEARALLAFSLAIGTHVIAADHPG-------PRQRVVR
Mvan_5303|M.vanbaalenii_PYR-1 ELIATISDDAGDVEARAMLAFSLVIGNHLIAAEHPGR------PRDRVVR
MAV_2167|M.avium_104 KAYRDYGFSPEDAKLRAELTFAAGIGLLHLTGSAEQ-------AQSLAQR
MSMEG_6293|M.smegmatis_MC2_155 KAFEDHGFDPDEARLRGEATFAAGIGMLHLIDSAEA-------LATSGRP
TH_0904|M.thermoresistible__bu QAFLDHGFDPADADLRANATFAAGIGFLHLAGDRPG-------AHGIAHR
MMAR_3423|M.marinum_M QAFCDYGFDADEAEMRANTAFAAGLGLLHMSGSALKGLFGSALKRQTAAP
MUL_2701|M.ulcerans_Agy99 QAFCDYGFDADEAEMRANTAFAAVLGLLHMSGSALKGLFGSALKRQTAAP
Mb3081|M.bovis_AF2122/97 VLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGG-------HTLQTLG
Rv3055|M.tuberculosis_H37Rv VLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGG-------HTLQTLG
MAB_3078|M.abscessus_ATCC_1997 KHYIEAGFTPARADTLARIGFSILVGAQQFGTRVDHK------RLNSALD
:.
Mflv_1468|M.gilvum_PYR-GCK DATRLILAGVTPV------
Mvan_5303|M.vanbaalenii_PYR-1 DAARLLLGEMTPM------
MAV_2167|M.avium_104 ER--FLDLMLTEAGVASDH
MSMEG_6293|M.smegmatis_MC2_155 DR--FLDIMLAPAS-----
TH_0904|M.thermoresistible__bu ER--FLELMLTP-------
MMAR_3423|M.marinum_M ERNWFLEFLLRE-------
MUL_2701|M.ulcerans_Agy99 ERNWFLEFLLRE-------
Mb3081|M.bovis_AF2122/97 DAWESLARKLCGR------
Rv3055|M.tuberculosis_H37Rv DAWESLARKLCGR------
MAB_3078|M.abscessus_ATCC_1997 EYSAWVNSSVSAEVTTSH-
: : :