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MGAVSSREAFFEAGLEVLSDRGYGGLKLATVCQRLGVTTGSFYHYFANWGSYTGQLVAHWHEGLTVRVVE AVQSEADPRRRIGHLIEVGLALPHGAESAIRVWSFIDPQVHEVQAAVDRQRFDVLYDSAIQILDSPRQAE LFAAWAVYLLVGYEQAILPRDISSLRWIVSQLLEALDSGRFDSVPRDE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0745 | - | - | 100% (188) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4460 | - | 1e-08 | 28.87% (142) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1468 | - | 5e-07 | 26.00% (150) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0149 | - | 5e-06 | 22.42% (165) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0144 | - | 5e-06 | 22.42% (165) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3078 | - | 2e-20 | 33.33% (150) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3423 | - | 2e-10 | 35.40% (113) | putative transcriptional regulatory protein |
| M. avium 104 | MAV_5101 | - | 3e-65 | 61.62% (185) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0091 | - | 3e-63 | 60.22% (181) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_1277 | - | 3e-63 | 59.56% (183) | putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_2701 | - | 2e-10 | 31.94% (144) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0102 | - | 6e-77 | 71.28% (188) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0745|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0102|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_5101|M.avium_104 --------------------------------------------------
MSMEG_0091|M.smegmatis_MC2_155 --------------------------------------------------
TH_1277|M.thermoresistible__bu --------------------------------------------------
MMAR_3423|M.marinum_M --------------------------------------------------
MUL_2701|M.ulcerans_Agy99 --------------------------------------------------
Mb0149|M.bovis_AF2122/97 MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
Rv0144|M.tuberculosis_H37Rv MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
MAB_3078|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0745|M.gilvum_PYR-GCK ---------------------------------MGAVSSREAFFEAGLEV
Mvan_0102|M.vanbaalenii_PYR-1 ---------------------------------MGAVASRESFFKTGLDV
MAV_5101|M.avium_104 --------------------------MPTKVPFMGNGASRSAYFEKGLEI
MSMEG_0091|M.smegmatis_MC2_155 ------------------------------MTSMASVVSRESYFDTGMDV
TH_1277|M.thermoresistible__bu -------------------------------------VTREAYFETGLAV
MMAR_3423|M.marinum_M --------------------------MAGRGTSGNRRLGVDDWVQAGFEI
MUL_2701|M.ulcerans_Agy99 --------------------------MAGRSTSGNRRLGVDDWVQAGFEI
Mb0149|M.bovis_AF2122/97 ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
Rv0144|M.tuberculosis_H37Rv ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
MAB_3078|M.abscessus_ATCC_1997 ---------------------------------MTEKVSRDDYFTAAFEL
. . . :
Mflv_0745|M.gilvum_PYR-GCK LSDRGYGGLKLATVCQRLGVTTGSFYHYFANWGSYTGQLVAHWHEGLTVR
Mvan_0102|M.vanbaalenii_PYR-1 LADLGYGGLKLAEVCDRLGVTTGSFYHYFPNWPAYSQELVGHWYEGMTLK
MAV_5101|M.avium_104 LSEVGYGGLKLAEVCLRVGVSTGSFYHFFDNWPKYTRELIEHWQQTNTIR
MSMEG_0091|M.smegmatis_MC2_155 LSDLGYGGLKLAEVCNRLGVTTGSFYHYFPNWSAYTRELIEHWREARTLR
TH_1277|M.thermoresistible__bu LADLGYGGLKLAEVCNRLGVTTGSFYHYFSGWPTYTRELIEFWRRERTTA
MMAR_3423|M.marinum_M LAEEGLSSLKLDQLCARLGVTKGSFYWHFADMEGYRHALVEAWAQFRDED
MUL_2701|M.ulcerans_Agy99 LAEEGLISLKLDQLCARLGVTKGSFYWHFADMEGYRHALVEAWAQFRDED
Mb0149|M.bovis_AF2122/97 FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
Rv0144|M.tuberculosis_H37Rv FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
MAB_3078|M.abscessus_ATCC_1997 LAAGGKSALTTTAVCRRIGMTTGSLYHHFGSGAAFYRAVIDYWENDVTVA
:: * . . :. * .:: :: .* . :: .
Mflv_0745|M.gilvum_PYR-GCK VVEAVQSEADPRRRIGHLIEVGLALP--HGAESAIRVWSFIDPQVHEVQA
Mvan_0102|M.vanbaalenii_PYR-1 VVDTVQAETDPRLRIDRLIEAGLTLP--HSAEAAIRVWSGVDPHVGSVQE
MAV_5101|M.avium_104 LAEWIEAEPDPRRRIDRIIDIGLNLP--HGAEAAIRAWSSTDPEVYAVQK
MSMEG_0091|M.smegmatis_MC2_155 VVEAVRADPDPHRRVETLIREALALP--HGAEAAIRVWSSLDPDVYTVQS
TH_1277|M.thermoresistible__bu IIESVRDTPDPRRRIGTLVQESLQLP--HGAEAAIRVWSSFDPDVYEVQV
MMAR_3423|M.marinum_M RDEIEGLREVEPRERLALMMALLARPRLWKLERAMREWARSDKTVAAAVL
MUL_2701|M.ulcerans_Agy99 RDEIEGLSEVEPRERLALMMALLARPRLWKLERAMREWARSDKTVAAAVL
Mb0149|M.bovis_AF2122/97 GIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELS
Rv0144|M.tuberculosis_H37Rv GIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELS
MAB_3078|M.abscessus_ATCC_1997 QRRRVDAVADPRERLATLEQAAREAD--HEVEKAIRSWAMADRYVAAAQQ
. : . *: : :
Mflv_0745|M.gilvum_PYR-GCK AVDRQRFDVLYDSAIQILDSPRQ-AELFAAWAVYLLVGYEQAILPRDISS
Mvan_0102|M.vanbaalenii_PYR-1 AVDRQRFDVMRESALEVLRNPRQ-AELFAAWAVYLLVGYEQASLPADVDG
MAV_5101|M.avium_104 EVDQERHRILRDSAVQILHDDRQ-AQLFADWAVYLLVGYEQATLPPDKEA
MSMEG_0091|M.smegmatis_MC2_155 VVDRLRYDILFEAAREIIGDDRN-AGYFAAWGVYVIVGYEQSTLPRDGDA
TH_1277|M.thermoresistible__bu AVDRQRFDIMYESALEVLGNERQ-AHVFASLTMYILVGYEQATLPRDPGV
MMAR_3423|M.marinum_M SADRRMVRAVQQAFCDYGFDADE-AEMRANTAFAAGLGLLHMSGSALKGL
MUL_2701|M.ulcerans_Agy99 SADRRMVRAVQQAFCDYGFDADE-AEMRANTAFAAVLGLLHMSGSALKGL
Mb0149|M.bovis_AF2122/97 RTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVGFY
Rv0144|M.tuberculosis_H37Rv RTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVGFY
MAB_3078|M.abscessus_ATCC_1997 RVDQVRHEHLTKHYIEAGFTPAR-ADTLARIGFSILVGAQQFGTRVDHKR
.:. . . . * .
Mflv_0745|M.gilvum_PYR-GCK LRWIVSQLLEALDSGRFDSVPRDE------
Mvan_0102|M.vanbaalenii_PYR-1 LRWIVGQLLEALDSGRFTSVPGRE------
MAV_5101|M.avium_104 LQWIVGQLLDALDAGRFASAPLKKG-----
MSMEG_0091|M.smegmatis_MC2_155 LGWIAFQLRDALSTGRFAPSSDPTHGNTLN
TH_1277|M.thermoresistible__bu LAWIAEQVLRTLDSGGFATIPG---GE---
MMAR_3423|M.marinum_M FGSALKRQTAAPERNWFLEFLLRE------
MUL_2701|M.ulcerans_Agy99 FGSALKRQTAAPERNWFLEFLLRE------
Mb0149|M.bovis_AF2122/97 IGFVGSYQRMATITDSFQQLLAGTLWRPPT
Rv0144|M.tuberculosis_H37Rv IGFVGSYQRMATITDSFQQLLAGTLWRPPT
MAB_3078|M.abscessus_ATCC_1997 LNSALDEYSAWVNSSVSAEVTTSH------
: .