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SGSSESATAGSDSRPRQVMNVAVLAESELGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVAV GTLYRYFPSKVHLLVSALGREFERIDAKTDRAALAAGATAYQRLNIMVGKLNRAMQRNPLLTEAMTRAFV FADASAAGEVDHVGKLMDSMFARAMSDGEPTEDQYHIARVISDVWLSNLLAWLTRRASATDVAKRLDLAV RLLIGDGDQPKI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1459 | - | - | 100% (223) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4581 | - | 3e-45 | 48.95% (190) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3506 | - | 7e-08 | 29.44% (180) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3605 | - | 7e-96 | 90.91% (198) | transcriptional regulatory protein TetR-family |
| M. tuberculosis H37Rv | Rv3574 | - | 7e-96 | 90.91% (198) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_00717 | - | 1e-05 | 28.57% (105) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0579c | - | 4e-81 | 72.02% (218) | TetR family transcriptional regulator |
| M. marinum M | MMAR_5069 | - | 9e-95 | 90.82% (196) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0584 | - | 5e-95 | 90.82% (196) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6042 | - | 1e-103 | 95.12% (205) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1745 | - | 1e-103 | 85.59% (222) | TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) |
| M. ulcerans Agy99 | MUL_4145 | - | 6e-95 | 90.82% (196) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5312 | - | 1e-114 | 91.91% (235) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1459|M.gilvum_PYR-GCK ------------MSGSSESAT------------AGSDSRPRQVMNVAVLA
Mvan_5312|M.vanbaalenii_PYR-1 ------------MSGTSEFAADKSQTSARATSGAGSESRPRQVMNVAVLA
MSMEG_6042|M.smegmatis_MC2_155 ------------------------------------------MTNVAVLS
Mb3605|M.bovis_AF2122/97 ---------------------------------------------MAVLA
Rv3574|M.tuberculosis_H37Rv ---------------------------------------------MAVLA
MMAR_5069|M.marinum_M ---------------------------------------------MAVLA
MUL_4145|M.ulcerans_Agy99 ---------------------------------------------MAVLA
MAV_0584|M.avium_104 ---------------------------------------------MAVLA
TH_1745|M.thermoresistible__bu MSSSTGTNPGRGSDSTGSETNGAAATGAGSGSTGTSRTRGRQVTNVAVLT
MAB_0579c|M.abscessus_ATCC_199 -----------------MATPRTSSASEAAQSGDGDTDATSQPAAVSALS
MLBr_00717|M.leprae_Br4923 -------------------------------------------------M
Mflv_1459|M.gilvum_PYR-GCK ESELGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVAVGTLYR
Mvan_5312|M.vanbaalenii_PYR-1 ESELGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVAVGTLYR
MSMEG_6042|M.smegmatis_MC2_155 ESELGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVAVGTLYR
Mb3605|M.bovis_AF2122/97 ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
Rv3574|M.tuberculosis_H37Rv ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
MMAR_5069|M.marinum_M ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
MUL_4145|M.ulcerans_Agy99 ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
MAV_0584|M.avium_104 ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
TH_1745|M.thermoresistible__bu DSELGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVAVGTLYR
MAB_0579c|M.abscessus_ATCC_199 DDDLGSSAQRERRKRILDATLAIASKGGYEAVQMRTVAERADVAVGTLYR
MLBr_00717|M.leprae_Br4923 TTARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYH
: .:** .:* : .* *: *:: :*:**.*: . :*:
Mflv_1459|M.gilvum_PYR-GCK YFPSKVHLLVSALGREFERIDAKTDRAALAAGATAYQRLNIMVGKLNRAM
Mvan_5312|M.vanbaalenii_PYR-1 YFPSKVHLLVSALGREFERIDAKTDRSAFPAGATAYQRLNIMVGKLNRAM
MSMEG_6042|M.smegmatis_MC2_155 YFPSKVHLLVSALGREFERIDAKTDRAALAGG-TPYQRLNFMVGKLNRAM
Mb3605|M.bovis_AF2122/97 YFPSKVHLLVSALGREFSRIDAKTDRSAVAGA-TPFQRLNFMVGKLNRAM
Rv3574|M.tuberculosis_H37Rv YFPSKVHLLVSALGREFSRIDAKTDRSAVAGA-TPFQRLNFMVGKLNRAM
MMAR_5069|M.marinum_M YFPSKVHLLVSALGREFSRIDAKTDRSAMTGG-TPFQRLNFMVGKLNRAM
MUL_4145|M.ulcerans_Agy99 YFPSKVHLLVSALGREFSRIDAKTDRSAMTGG-TPFQRLNFMVGKLNRAM
MAV_0584|M.avium_104 YFPSKVHLLVSALGREFSRIDAKTDRAALTGG-TPFQRLNFMVGKLNRAM
TH_1745|M.thermoresistible__bu YFPSKVHLLVSALGREFERIDAKTDRSTLVGD-TPYERLNFMVSRLNRAM
MAB_0579c|M.abscessus_ATCC_199 YFPSKVHLLVSALEREFEQIDAKSDRNAVSGG-TPYERLHAAITRLNRNM
MLBr_00717|M.leprae_Br4923 YFPDKRAFFAAVVKDEADRLYAATN-IPPPAGLTMFEEVRVGVLAYMAYH
***.* ::.:.: * .:: * :: . . * ::.:. :
Mflv_1459|M.gilvum_PYR-GCK QRNPLLTEAMTRAFVFADASAAGEVDHVG-KLMDSMFARAMS-DGEPTED
Mvan_5312|M.vanbaalenii_PYR-1 QRNPLLTEAMTRAFVFADASAAGEVDHVG-KLMDSMFARAMS-DGEPTED
MSMEG_6042|M.smegmatis_MC2_155 QRNPLLTEAMTRAFVFADASAAGEVDHVG-KLMDSMFARAMS-DGEPTED
Mb3605|M.bovis_AF2122/97 QRNPLLTEAMTRAYVFADASAASEVDQVE-KLIDSMFARAMA-NGEPTED
Rv3574|M.tuberculosis_H37Rv QRNPLLTEAMTRAYVFADASAASEVDQVE-KLIDSMFARAMA-NGEPTED
MMAR_5069|M.marinum_M QRNPLLTEAMTRAYVFADASAATEVDQVE-KLIDSMFARAMA-DGEPTED
MUL_4145|M.ulcerans_Agy99 QRNPLLTEAMTRAYVFADASAATEVDQVE-KLIDSMFARAMA-DGEPTED
MAV_0584|M.avium_104 QRNPLLTEAMTRAYVFADASAASEVDQVE-KLIDSMFARAMA-DGEPTED
TH_1745|M.thermoresistible__bu QRNPLLTEAMTRAFVFADASAAGEVDHVG-RLMDSMFARAMA-DGEPTED
MAB_0579c|M.abscessus_ATCC_199 QRNPLLTEAMTRALVFADASAAGEVDHVG-RLMDGIFARAMAGEDDPTDA
MLBr_00717|M.leprae_Br4923 KQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSRIGDVVSVVPES
::** : * . :*. *.. : :: :::* . .:
Mflv_1459|M.gilvum_PYR-GCK QYH-----IARVISDVWLSNLLAWLTRRAS--ATDVAKRLDLAVRLLIGD
Mvan_5312|M.vanbaalenii_PYR-1 QYH-----IARVISDVWLSNLLAWLTRRAS--ATDVAKRLDLAVRLLIGD
MSMEG_6042|M.smegmatis_MC2_155 QYH-----IARVISDVWLSNLLAWLTRRAS--ATDVSKRLDLAVRLLIGT
Mb3605|M.bovis_AF2122/97 QYH-----IARVISDVWLSNLLAWLTRRAS--ATDVSKRLDLAVRLLIGD
Rv3574|M.tuberculosis_H37Rv QYH-----IARVISDVWLSNLLAWLTRRAS--ATDVSKRLDLAVRLLIGD
MMAR_5069|M.marinum_M QYH-----IARVISDVWLSNLLAWLTRRAS--ATDVSKRLDLAVRLLIGD
MUL_4145|M.ulcerans_Agy99 QYH-----IARVISDVWLSNLLAWLTRRAS--ATDVSKRLDLAVRLLIGD
MAV_0584|M.avium_104 QYH-----IARVISDVWLSNLLAWLTRRAS--ATDVSKRLDLAVRLLLGE
TH_1745|M.thermoresistible__bu QYH-----IARVISDVWLSNLLAWLTRRAS--ATDVSKRLELAVRLLVGD
MAB_0579c|M.abscessus_ATCC_199 QFH-----IARVISDVWTSNMIAWLTRRAS--ATDVSHRLDRTVRLLLGI
MLBr_00717|M.leprae_Br4923 KLHPDIERDLRVIVHGWLAFTFEVCRQRIMDPSTDADRLADSCAHALLDA
: * *** . * : : :* :**. : : .: *:.
Mflv_1459|M.gilvum_PYR-GCK GDQPKI-----------------
Mvan_5312|M.vanbaalenii_PYR-1 GDQPKI-----------------
MSMEG_6042|M.smegmatis_MC2_155 EEQPKI-----------------
Mb3605|M.bovis_AF2122/97 QDSA-------------------
Rv3574|M.tuberculosis_H37Rv QDSA-------------------
MMAR_5069|M.marinum_M QEATA------------------
MUL_4145|M.ulcerans_Agy99 QEATA------------------
MAV_0584|M.avium_104 HG---------------------
TH_1745|M.thermoresistible__bu GKNPKV-----------------
MAB_0579c|M.abscessus_ATCC_199 T----------------------
MLBr_00717|M.leprae_Br4923 IARVPEISKELADAMAIARQPPQ