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SSTLTDDAKTMLSKPNPAVIATVRSDGHPVSAATWYLLRDDGLLVNMDVARKRLQHLRNDPRVSLTVLDS DDWYTHVTVIGHVTEIYDDDGLTDIDALSRHYQGTQYPDRERPRVSALIAIDRVHGWGAQKNNDQPDGRP Q*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1362 | - | - | 100% (142) | pyridoxamine 5'-phosphate oxidase-related, FMN-binding |
| M. gilvum PYR-GCK | Mflv_0791 | - | 6e-05 | 25.36% (138) | pyridoxamine 5'-phosphate oxidase-related, FMN-binding |
| M. gilvum PYR-GCK | Mflv_2137 | - | 1e-04 | 26.36% (110) | pyridoxamine 5'-phosphate oxidase-related, FMN-binding |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1186 | - | 2e-06 | 29.73% (111) | hypothetical protein Mb1186 |
| M. tuberculosis H37Rv | Rv1155 | - | 9e-06 | 29.25% (106) | hypothetical protein Rv1155 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2595 | - | 2e-08 | 31.39% (137) | putative pyridoxamine 5'-phosphate oxidase |
| M. marinum M | MMAR_4298 | - | 2e-05 | 27.78% (126) | hypothetical protein MMAR_4298 |
| M. avium 104 | MAV_3840 | - | 1e-06 | 27.01% (137) | pyridoxamine 5'-phosphate oxidase family protein |
| M. smegmatis MC2 155 | MSMEG_6848 | - | 7e-08 | 28.71% (101) | putative oxidoreductase |
| M. thermoresistible (build 8) | TH_4219 | - | 4e-07 | 32.26% (93) | PUTATIVE pyridoxamine 5'-phosphate oxidase-related, |
| M. ulcerans Agy99 | MUL_0996 | - | 3e-05 | 27.27% (121) | hypothetical protein MUL_0996 |
| M. vanbaalenii PYR-1 | Mvan_2494 | - | 6e-06 | 28.68% (136) | pyridoxamine 5'-phosphate oxidase-related, FMN-binding |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1186|M.bovis_AF2122/97 --------------------------------------------------
Rv1155|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4298|M.marinum_M --------------------------------------------------
MUL_0996|M.ulcerans_Agy99 --------------------------------------------------
MAB_2595|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6848|M.smegmatis_MC2_155 MGTFVISGGTDGIGKAIAANRLKLGHEVVVIGRDTAKGQAFLDSAADIGA
Mflv_1362|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2494|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3840|M.avium_104 --------------------------------------------------
TH_4219|M.thermoresistible__bu --------------------------------------------------
Mb1186|M.bovis_AF2122/97 --------------------------------------------------
Rv1155|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4298|M.marinum_M --------------------------------------------------
MUL_0996|M.ulcerans_Agy99 --------------------------------------------------
MAB_2595|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6848|M.smegmatis_MC2_155 VDRAHFVVADLSLVSQTRRAIDEIGNCISEIDGLVLCARHFRTTRAVTAE
Mflv_1362|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2494|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3840|M.avium_104 --------------------------------------------------
TH_4219|M.thermoresistible__bu --------------------------------------------------
Mb1186|M.bovis_AF2122/97 --------------------------------------------------
Rv1155|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4298|M.marinum_M --------------------------------------------------
MUL_0996|M.ulcerans_Agy99 --------------------------------------------------
MAB_2595|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6848|M.smegmatis_MC2_155 GLEHTFALYYLSRFVLSHRLVGLLDAAEAPVILNVSGPGSGTDSIRWDDL
Mflv_1362|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2494|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3840|M.avium_104 --------------------------------------------------
TH_4219|M.thermoresistible__bu --------------------------------------------------
Mb1186|M.bovis_AF2122/97 --------------------------------------------------
Rv1155|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4298|M.marinum_M --------------------------------------------------
MUL_0996|M.ulcerans_Agy99 --------------------------------------------------
MAB_2595|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6848|M.smegmatis_MC2_155 GGEHDYEPQRILAQGGQLNDLLGVGFARRRVSPKTRYVLVHPGVVNTGFS
Mflv_1362|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2494|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3840|M.avium_104 --------------------------------------------------
TH_4219|M.thermoresistible__bu --------------------------------------------------
Mb1186|M.bovis_AF2122/97 --------------------------------------------------
Rv1155|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4298|M.marinum_M --------------------------------------------------
MUL_0996|M.ulcerans_Agy99 --------------------------------------------------
MAB_2595|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6848|M.smegmatis_MC2_155 GEYDAATADRIEQIRATAQPVEDAIVPILDIVDHPPAEPLTAVVEGRPID
Mflv_1362|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2494|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3840|M.avium_104 --------------------------------------------------
TH_4219|M.thermoresistible__bu --------------------------------------------------
Mb1186|M.bovis_AF2122/97 ---------------------------MARQVFDDKLLAVISGNSIGVLA
Rv1155|M.tuberculosis_H37Rv ---------------------------MARQVFDDKLLAVISGNSIGVLA
MMAR_4298|M.marinum_M ---------------------------MGRQVFDDKLLAVISGNSIGVLA
MUL_0996|M.ulcerans_Agy99 ---------------------------MGRQVFDDKLLAVISGNSIGVLA
MAB_2595|M.abscessus_ATCC_1997 ---------------------------MASDRFDP--HALITESRLGILA
MSMEG_6848|M.smegmatis_MC2_155 VHGPAFDAALADRLYDQTTVLLGSLASAAMGVSPARLRQVLDAPVFGTVA
Mflv_1362|M.gilvum_PYR-GCK ----------------------------MSSTLTDDAKTMLSKPNPAVIA
Mvan_2494|M.vanbaalenii_PYR-1 ------------------------------MRLNDAARDLIGNGADATLV
MAV_3840|M.avium_104 ---------------------MGTNQRASIVMSDDEIADFVVKSRTGTLA
TH_4219|M.thermoresistible__bu -----------------------------MELTDDVIAFLSEGTRTGKLG
. . :
Mb1186|M.bovis_AF2122/97 TIKHDGRPQLSNVQYHFD--PRKLLIQVSIAEPRAKTRNLRRDPRASILV
Rv1155|M.tuberculosis_H37Rv TIKHDGRPQLSNVQYHFD--PRKLLIQVSIAEPRAKTRNLRRDPRASILV
MMAR_4298|M.marinum_M TIKHDGRPQLSNVQYYFD--ARKLVVQVSITEPRAKTRNLRRDPRASILV
MUL_0996|M.ulcerans_Agy99 TIKHDGRPQLSNVQYYFD--ARKLVVQVSITEPRAKTRNLRRDPRASILV
MAB_2595|M.abscessus_ATCC_1997 TIKSSGLPQLSPVTPYYD--RDNGIIYVSMTDGRAKTANLRRDPRAALEC
MSMEG_6848|M.smegmatis_MC2_155 TIDPDGAPQQSVVWVGRD--GDD--VLFAVATGSRKERNLRRDPRVSILL
Mflv_1362|M.gilvum_PYR-GCK TVRSDGHPVSAATWYLLR--DDG--LLVNMDVARKRLQHLRNDPRVSLTV
Mvan_2494|M.vanbaalenii_PYR-1 TLNPDGSPQVSLVWVALQSTADGDELVSAHLADYKKLRNVRRDPRVAVTI
MAV_3840|M.avium_104 TIGRDGQPHLTAMWYAVV----DGEIWLETKAKSQKAINLKRDPRVSFLI
TH_4219|M.thermoresistible__bu YVAADGRPLVVPVWFIVD----GQTLVFNTDQNTAKARAMRRDPRVTLCV
: .* * : : ::.***.:.
Mb1186|M.bovis_AF2122/97 DA---DDGWSYAVAEGTAQLTPPAAAPDDDTVEALIALYRNIAG-EHPDW
Rv1155|M.tuberculosis_H37Rv DA---DDGWSYAVAEGTAQLTPPAAAPDDDTVEALIALYRNIAG-EHSDW
MMAR_4298|M.marinum_M DA---DDGWSYAVAEGTAELTPPAAAPDDETVEALIALYRNIAG-EHPDW
MUL_0996|M.ulcerans_Agy99 DA---DDGRSYAVAEGTAELTPPAAAPDDETVEALIALYRNIAG-EHPDW
MAB_2595|M.abscessus_ATCC_1997 TS---SDGRAWATAEGHVTLTGPGADPDGPEVQALVDYYRGAAG-EHPDW
MSMEG_6848|M.smegmatis_MC2_155 SPP--DEPYTYAVIHGKATLHTEGGHQLRDALAVKYTGKTYAEG-NADAA
Mflv_1362|M.gilvum_PYR-GCK LDS--DDWYTHVTVIGHVTEIYD-----DDGLTDIDALSRHYQGTQYPDR
Mvan_2494|M.vanbaalenii_PYR-1 VS----TGGVTGVMRPYLSITGTARVVEGGAPELLADLARTLAAPGTPFP
MAV_3840|M.avium_104 EDGDTYDTLRGVSFEGVAELVDDPDVAHRVGVSVFERYTGPYTDEMKPFV
TH_4219|M.thermoresistible__bu DDE--QPPYSFVQVQGTTSISEDPADLLDIATRIGGRYMGADRAEEFGRR
Mb1186|M.bovis_AF2122/97 DDYRQAMVTDRRVLLTLPISHVYGLPPGMR---------------
Rv1155|M.tuberculosis_H37Rv DDYRQAMVTDRRVLLTLPISHVYGLPPGMR---------------
MMAR_4298|M.marinum_M DEYREAMVTDRRVLLTLPISHVYGLPPGKR---------------
MUL_0996|M.ulcerans_Agy99 DEYREAMVIDRRVLLTLPISHVYGLPPGKR---------------
MAB_2595|M.abscessus_ATCC_1997 DEYRSVMVSDRRVLMALRVERVYGQKLG-----------------
MSMEG_6848|M.smegmatis_MC2_155 ARYGDVAMTVVRVTPERTVGRL-----------------------
Mflv_1362|M.gilvum_PYR-GCK ERPRVSALIAIDRVHGWGAQKNNDQPDGRPQ--------------
Mvan_2494|M.vanbaalenii_PYR-1 PADAPPGFLTRIRIDKVGGVGPWAP--------------------
MAV_3840|M.avium_104 EQMMNKRVCVRIVARRARSWDHRKLGLPPMPVGGSTAPAVLGTDR
TH_4219|M.thermoresistible__bu NGVPGELIVRITPRKVITAFNVAD---------------------
.