For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSWTRTEMAARAARELRDGDYVNLGIGLPTLIPDHLPEGSDVTLHAENGILGVGPFPYDDEVDPDLVNAG KQTVSVVAGASFFDSATSFAMIRGGHVDVAVLGGMQVAVNGDLANWMVPGSMVKGMGGAMDLVNGAAKVI VLMDHVSKNGAAKLVSSCDLPLTGKAVVQRVITDLGVFDVTGTEFGVVELSPGVDLDEVAAKTGAPVSDH RHRLSAASSERDRMPSLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1350 | - | - | 100% (228) | 3-oxoacid CoA-transferase, B subunit |
| M. gilvum PYR-GCK | Mflv_0525 | - | 5e-47 | 52.46% (183) | 3-oxoacid CoA-transferase, B subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2531c | scoB | 1e-75 | 62.44% (205) | succinyl-CoA:3-ketoacid-coenzyme A transferase subunit beta |
| M. tuberculosis H37Rv | Rv2503c | scoB | 1e-75 | 62.44% (205) | succinyl-CoA:3-ketoacid-coenzyme A transferase subunit beta |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3850 | scoB | 1e-74 | 61.35% (207) | succinyl-CoA:3-ketoacid-coenzyme A transferase (beta |
| M. avium 104 | MAV_4786 | - | 3e-70 | 62.19% (201) | succinyl-CoA:3-ketoacid-coenzyme A transferase 1 |
| M. smegmatis MC2 155 | MSMEG_1899 | - | 1e-101 | 85.78% (211) | succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B |
| M. thermoresistible (build 8) | TH_1757 | - | 0.0001 | 39.34% (61) | POSSIBLE COA-TRANSFERASE (BETA SUBUNIT) |
| M. ulcerans Agy99 | MUL_3781 | scoB | 1e-73 | 60.87% (207) | succinyl-CoA:3-ketoacid-coenzyme a transferase (beta |
| M. vanbaalenii PYR-1 | Mvan_4892 | - | 1e-74 | 65.70% (207) | 3-oxoacid CoA-transferase, B subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1350|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1899|M.smegmatis_MC2_155 --------------------------------------------------
Mb2531c|M.bovis_AF2122/97 --------------------------------------------------
Rv2503c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3850|M.marinum_M --------------------------------------------------
MUL_3781|M.ulcerans_Agy99 --------------------------------------------------
Mvan_4892|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4786|M.avium_104 MSKVHPDAESALHGLLKDGITVAAGGFGLCGIPEKLIQALVDSGIKDLTI
TH_1757|M.thermoresistible__bu --------------------------------------------------
Mflv_1350|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1899|M.smegmatis_MC2_155 --------------------------------------------------
Mb2531c|M.bovis_AF2122/97 --------------------------------------------------
Rv2503c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3850|M.marinum_M --------------------------------------------------
MUL_3781|M.ulcerans_Agy99 --------------------------------------------------
Mvan_4892|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4786|M.avium_104 VGNNAGVDDFGMGLLLKGRQVKKVIASYVGENKEFERQVLSGELDLVLTP
TH_1757|M.thermoresistible__bu --------------------------------------------------
Mflv_1350|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1899|M.smegmatis_MC2_155 --------------------------------------------------
Mb2531c|M.bovis_AF2122/97 --------------------------------------------------
Rv2503c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3850|M.marinum_M --------------------------------------------------
MUL_3781|M.ulcerans_Agy99 --------------------------------------------------
Mvan_4892|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4786|M.avium_104 QGTLAEKLRAGGAGIPGFYTRTGYGTTLAEGKDTRVFDGVEYVLEEGIRA
TH_1757|M.thermoresistible__bu --------------------------------------------------
Mflv_1350|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1899|M.smegmatis_MC2_155 --------------------------------------------------
Mb2531c|M.bovis_AF2122/97 --------------------------------------------------
Rv2503c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3850|M.marinum_M --------------------------------------------------
MUL_3781|M.ulcerans_Agy99 --------------------------------------------------
Mvan_4892|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4786|M.avium_104 DLAIVKAWKGDKAGNLVYRKTARNFNPMIATCAAVTVAEVEELVEVGDLD
TH_1757|M.thermoresistible__bu --------------------------------------------------
Mflv_1350|M.gilvum_PYR-GCK -------------------------------MS------WTRTEMAARAA
MSMEG_1899|M.smegmatis_MC2_155 -------------------------------MS------WNRDDMAARAA
Mb2531c|M.bovis_AF2122/97 -------------------------------MSA---PGWSRDEMAARVA
Rv2503c|M.tuberculosis_H37Rv -------------------------------MSA---PGWSRDEMAARVA
MMAR_3850|M.marinum_M -------------------------------MS------WSRDGMAARVA
MUL_3781|M.ulcerans_Agy99 -------------------------------MS------WSRDGMAARVA
Mvan_4892|M.vanbaalenii_PYR-1 -------------------------------MTATFTTGWTRNQIAARAA
MAV_4786|M.avium_104 PDLIHTPGIYVDRIIQGIGYEKRIEFRTTSGGAALKNDSPIRERMAQRAA
TH_1757|M.thermoresistible__bu -------------------------------VSS-----VSRAEVCAVAC
: * :. ..
Mflv_1350|M.gilvum_PYR-GCK RELRDGD---YVNLGIGLPTLIP--DHLPEGSDVTLHAENGILGVGPFPY
MSMEG_1899|M.smegmatis_MC2_155 TELHDGD---YVNLGIGLPTLIP--DHLPAGSQVTLHSENGILGVGPFPY
Mb2531c|M.bovis_AF2122/97 AEFEDGQ---YVNLGIGMPTLIP--NHIPDGVHVVLHSENGILGVGPYPR
Rv2503c|M.tuberculosis_H37Rv AEFEDGQ---YVNLGIGMPTLIP--NHIPDGVHVVLHSENGILGVGPYPR
MMAR_3850|M.marinum_M TEFEDGQ---YINLGIGMPTLIP--NHIPEGVTVVLHSENGILGVGPYPI
MUL_3781|M.ulcerans_Agy99 TEFEDGQ---YINLGIGMSTLIP--NHIPEGVTVVLHSENGILGVGPYPI
Mvan_4892|M.vanbaalenii_PYR-1 AEMIDGQ---YVDLGIGLPTLIP--GHLSPGVRVILHSENGILGTGGYPD
MAV_4786|M.avium_104 KELRDGY---YVNLGIGIPTLVA--NFIPDDIQVTLQSENGLLGIGAYPS
TH_1757|M.thermoresistible__bu AELFRDAGEIMVSPMTPMASIGARLARLTFAPDILLTDGEAQLLADTPPL
*: . :. :.:: . :. : * :. * . *
Mflv_1350|M.gilvum_PYR-GCK DDEVDPDLVNAGKQTVSVVAGASFFDSATSFAMIRGGHVDVAVLGGMQVA
MSMEG_1899|M.smegmatis_MC2_155 DDEVDPDLVNAGKQTVSVVAGASYFDSATSFAMIRGGHVDVAVLGGMQVA
Mb2531c|M.bovis_AF2122/97 REDVDADLINAGKETVTTLPGAAFFSSSTSFGIIRGGHLDVAVLGAMQVS
Rv2503c|M.tuberculosis_H37Rv REDVDADLINAGKETVTTLPGAAFFSSSTSFGIIRGGHLDVAVLGAMQVS
MMAR_3850|M.marinum_M REELDADLINAGKETVTTLPGAAFFGSSTSFGIIRGGHLDVAVLGAMQVS
MUL_3781|M.ulcerans_Agy99 REEFDADLINAGKETVTTLPGAAFFGSSTSFGIIRGGHLDVAVLGAMQVS
Mvan_4892|M.vanbaalenii_PYR-1 EDSVDADLINAGKETVTVNRGAAFFDSATSFGMIRGGHIDAAVLGAMQVS
MAV_4786|M.avium_104 EDTVDPDLINAGKQTITSLPGSSFFSSADSFAMIRGGHIDLSILGALEVA
TH_1757|M.thermoresistible__bu GQTGPVEGWMPFGRVFETLAWGRRHVVMGANQIDRYGNQNLSALGPLQKP
: : . ... . . : : * *: : : ** :: .
Mflv_1350|M.gilvum_PYR-GCK VNGDLANWMVPGSMVKGMGGAMDLVNGAAKVIVLMDHVSKNGAAKLVSSC
MSMEG_1899|M.smegmatis_MC2_155 ANGDLANWMVPGSMVKGMGGAMDLVSGARRVIVLMDHVAKSGAAKLVSSC
Mb2531c|M.bovis_AF2122/97 VTGDLANWMIPGKMVKGMGGAMDLVHGARKVIVMMEHTAKDGSPKILERC
Rv2503c|M.tuberculosis_H37Rv VTGDLANWMIPGKMVKGMGGAMDLVHGARKVIVMMEHTAKDGSPKILERC
MMAR_3850|M.marinum_M VSGDLANWMIPGKMVKGMGGAMDLVHGARKVIVMMEHAAKDGSPKILERC
MUL_3781|M.ulcerans_Agy99 VSGDLANWMIPGKMVKGMGGAMDLVHGARKVIVMMEHAAKDGSPKILDRC
Mvan_4892|M.vanbaalenii_PYR-1 RNGDLANWMVPGKMVKGMGGAMDLVHGAARVIVVMEHTDRSGAPKIVDAC
MAV_4786|M.avium_104 SNGDLANWMVPGKMVKGPGGAMDLVSGVKRVIVLMDHTAKDGSPKVLEQC
TH_1757|M.thermoresistible__bu TRQMFGVRGAPGNTINHATSYWVGNHSTRVFGESVDVVSGIGWDKVDP--
:. **. :: . .. . :: . * *:
Mflv_1350|M.gilvum_PYR-GCK DLPLTGKAVVQRVITDLGVFDVTGTE--FGVVELSPGVDLDEVAAKTGAP
MSMEG_1899|M.smegmatis_MC2_155 TLPLTGKAVVSRVITDLGVFDVTGDG--FRVVELAPGVEFDHVAANTDAT
Mb2531c|M.bovis_AF2122/97 TLPLTGVGCVDRIVTELAVIDVCADG--LHLVQTAPGVSVDEVVAKTQPP
Rv2503c|M.tuberculosis_H37Rv TLPLTGVGCVDRIVTELAVIDVCADG--LHLVQTAPGVSVDEVVAKTQPP
MMAR_3850|M.marinum_M TLPLTGVGCVNRIVTELAVIDVCHDG--LHLIETAPDVSAEEVVAKTQPP
MUL_3781|M.ulcerans_Agy99 TLPLTGVGCVNRIVTELAVIDVCHDG--LHLIETAPDVSAEEVVAKTQPP
Mvan_4892|M.vanbaalenii_PYR-1 TLPLTGQGVVDRIITNLCVIDVPGDGT-LVLRELAPGVTVDDVVAATGAE
MAV_4786|M.avium_104 TLPLTGKGVVDMIITNLCVFDVEPGRG-LLLTELHPGVTVEEVRAKTGCD
TH_1757|M.thermoresistible__bu DNPAFRFVNIHRVVTNLGVFDFSGPNRQMRAVSLHPGITPDEVAENTGFE
* : ::*:* *:*. : . *.: :.* *
Mflv_1350|M.gilvum_PYR-GCK VSDHRHRLSAASSERDRMPSLA---------------
MSMEG_1899|M.smegmatis_MC2_155 LVDG------------RVGSLV---------------
Mb2531c|M.bovis_AF2122/97 LVLR------------DLATQ----------------
Rv2503c|M.tuberculosis_H37Rv LVLR------------DLATQ----------------
MMAR_3850|M.marinum_M LVLD------------DLVAR----------------
MUL_3781|M.ulcerans_Agy99 LVLD------------DLVAR----------------
Mvan_4892|M.vanbaalenii_PYR-1 LTVA------------L--------------------
MAV_4786|M.avium_104 FTVAL--------------------------------
TH_1757|M.thermoresistible__bu IHDLDKAEPTRLPSDEELRLLREVIDPKSVRDREIRR
.