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TRTVDASTRACVEHLDRGPLDRREIAAMIARDIPAGSYVNLGIGQPTMVADFLDPAAGVVLHTENGMLGM GGEAIGDAIDPDLTNAGKIPVTETPGASYFHHADSFAMMRGGHLDVCVLGAFQVSERGDLANWHTGAPDA IPAVGGAMDLAIGAKSVLVMMTLFAKDGTAKLVPSCSYPLTGLRCVNRVYTDYAVFDIDHTGGGQLRVLH TFGLSIAALEERMRMALSCDGRVADLRQC*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0525 | - | - | 100% (240) | 3-oxoacid CoA-transferase, B subunit |
| M. gilvum PYR-GCK | Mflv_1350 | - | 5e-47 | 52.46% (183) | 3-oxoacid CoA-transferase, B subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2531c | scoB | 2e-45 | 50.28% (177) | succinyl-CoA:3-ketoacid-coenzyme A transferase subunit beta |
| M. tuberculosis H37Rv | Rv2503c | scoB | 2e-45 | 50.28% (177) | succinyl-CoA:3-ketoacid-coenzyme A transferase subunit beta |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3850 | scoB | 8e-47 | 50.28% (181) | succinyl-CoA:3-ketoacid-coenzyme A transferase (beta |
| M. avium 104 | MAV_4786 | - | 4e-46 | 45.07% (213) | succinyl-CoA:3-ketoacid-coenzyme A transferase 1 |
| M. smegmatis MC2 155 | MSMEG_1899 | - | 3e-47 | 52.72% (184) | succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3781 | scoB | 7e-46 | 49.72% (181) | succinyl-CoA:3-ketoacid-coenzyme a transferase (beta |
| M. vanbaalenii PYR-1 | Mvan_0565 | - | 1e-138 | 99.17% (240) | 3-oxoacid CoA-transferase, B subunit |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3850|M.marinum_M --------------------------------------------------
MUL_3781|M.ulcerans_Agy99 --------------------------------------------------
Mb2531c|M.bovis_AF2122/97 --------------------------------------------------
Rv2503c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4786|M.avium_104 MSKVHPDAESALHGLLKDGITVAAGGFGLCGIPEKLIQALVDSGIKDLTI
MSMEG_1899|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0525|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0565|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3850|M.marinum_M --------------------------------------------------
MUL_3781|M.ulcerans_Agy99 --------------------------------------------------
Mb2531c|M.bovis_AF2122/97 --------------------------------------------------
Rv2503c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4786|M.avium_104 VGNNAGVDDFGMGLLLKGRQVKKVIASYVGENKEFERQVLSGELDLVLTP
MSMEG_1899|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0525|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0565|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3850|M.marinum_M --------------------------------------------------
MUL_3781|M.ulcerans_Agy99 --------------------------------------------------
Mb2531c|M.bovis_AF2122/97 --------------------------------------------------
Rv2503c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4786|M.avium_104 QGTLAEKLRAGGAGIPGFYTRTGYGTTLAEGKDTRVFDGVEYVLEEGIRA
MSMEG_1899|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0525|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0565|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3850|M.marinum_M --------------------------------------------------
MUL_3781|M.ulcerans_Agy99 --------------------------------------------------
Mb2531c|M.bovis_AF2122/97 --------------------------------------------------
Rv2503c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4786|M.avium_104 DLAIVKAWKGDKAGNLVYRKTARNFNPMIATCAAVTVAEVEELVEVGDLD
MSMEG_1899|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0525|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0565|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3850|M.marinum_M ----------------------------------MS---WSRDGMAARVA
MUL_3781|M.ulcerans_Agy99 ----------------------------------MS---WSRDGMAARVA
Mb2531c|M.bovis_AF2122/97 ----------------------------------MSAPGWSRDEMAARVA
Rv2503c|M.tuberculosis_H37Rv ----------------------------------MSAPGWSRDEMAARVA
MAV_4786|M.avium_104 PDLIHTPGIYVDRIIQGIGYEKRIEFRTTSGGAALKNDSPIRERMAQRAA
MSMEG_1899|M.smegmatis_MC2_155 ----------------------------------MS---WNRDDMAARAA
Mflv_0525|M.gilvum_PYR-GCK -------------------MTRTVDASTRACVEHLDRGPLDRREIAAMIA
Mvan_0565|M.vanbaalenii_PYR-1 -------------------MTRTVDASTRACVEHLDRGPLDRREIAAMIA
:. * :* *
MMAR_3850|M.marinum_M TEFEDGQYINLGIGMPTLIPNHIPEGVTVVLHSENGILGVGPYPIREELD
MUL_3781|M.ulcerans_Agy99 TEFEDGQYINLGIGMSTLIPNHIPEGVTVVLHSENGILGVGPYPIREEFD
Mb2531c|M.bovis_AF2122/97 AEFEDGQYVNLGIGMPTLIPNHIPDGVHVVLHSENGILGVGPYPRREDVD
Rv2503c|M.tuberculosis_H37Rv AEFEDGQYVNLGIGMPTLIPNHIPDGVHVVLHSENGILGVGPYPRREDVD
MAV_4786|M.avium_104 KELRDGYYVNLGIGIPTLVANFIPDDIQVTLQSENGLLGIGAYPSEDTVD
MSMEG_1899|M.smegmatis_MC2_155 TELHDGDYVNLGIGLPTLIPDHLPAGSQVTLHSENGILGVGPFPYDDEVD
Mflv_0525|M.gilvum_PYR-GCK RDIPAGSYVNLGIGQPTMVADFLDPAAGVVLHTENGMLGMGGEAIGDAID
Mvan_0565|M.vanbaalenii_PYR-1 RDIPAGSYVNLGIGQPTMVADFLDPAAGVVLHTENGMLGMGGEAIGDAID
:: * *:***** .*::.:.: *.*::***:**:* . : .*
MMAR_3850|M.marinum_M ADLINAGKETVTTLPGAAFFGSSTSFGIIRGGHLDVAVLGAMQVSVSGDL
MUL_3781|M.ulcerans_Agy99 ADLINAGKETVTTLPGAAFFGSSTSFGIIRGGHLDVAVLGAMQVSVSGDL
Mb2531c|M.bovis_AF2122/97 ADLINAGKETVTTLPGAAFFSSSTSFGIIRGGHLDVAVLGAMQVSVTGDL
Rv2503c|M.tuberculosis_H37Rv ADLINAGKETVTTLPGAAFFSSSTSFGIIRGGHLDVAVLGAMQVSVTGDL
MAV_4786|M.avium_104 PDLINAGKQTITSLPGSSFFSSADSFAMIRGGHIDLSILGALEVASNGDL
MSMEG_1899|M.smegmatis_MC2_155 PDLVNAGKQTVSVVAGASYFDSATSFAMIRGGHVDVAVLGGMQVAANGDL
Mflv_0525|M.gilvum_PYR-GCK PDLTNAGKIPVTETPGASYFHHADSFAMMRGGHLDVCVLGAFQVSERGDL
Mvan_0565|M.vanbaalenii_PYR-1 PDLTNAGKIPVTETPGASYFHHADSFAMVRGGHLDVCVLGAFQVSERGDL
.** **** .:: .*:::* : **.::****:*:.:**.::*: ***
MMAR_3850|M.marinum_M ANWMIPG-KMVKGMGGAMDLVHGARKVIVMMEHAAKDGSPKILERCTLPL
MUL_3781|M.ulcerans_Agy99 ANWMIPG-KMVKGMGGAMDLVHGARKVIVMMEHAAKDGSPKILDRCTLPL
Mb2531c|M.bovis_AF2122/97 ANWMIPG-KMVKGMGGAMDLVHGARKVIVMMEHTAKDGSPKILERCTLPL
Rv2503c|M.tuberculosis_H37Rv ANWMIPG-KMVKGMGGAMDLVHGARKVIVMMEHTAKDGSPKILERCTLPL
MAV_4786|M.avium_104 ANWMVPG-KMVKGPGGAMDLVSGVKRVIVLMDHTAKDGSPKVLEQCTLPL
MSMEG_1899|M.smegmatis_MC2_155 ANWMVPG-SMVKGMGGAMDLVSGARRVIVLMDHVAKSGAAKLVSSCTLPL
Mflv_0525|M.gilvum_PYR-GCK ANWHTGAPDAIPAVGGAMDLAIGAKSVLVMMTLFAKDGTAKLVPSCSYPL
Mvan_0565|M.vanbaalenii_PYR-1 ANWHTGAPDAIPAVGGAMDLAIGAKSVLVMMTLFAKDGTAKLVPSCSYPL
*** . . : . ******. *.: *:*:* **.*:.*:: *: **
MMAR_3850|M.marinum_M TGVGCVNRIVTELAVIDVCHD-GLHLIETAP-DVSAEEVVAKTQPPLVLD
MUL_3781|M.ulcerans_Agy99 TGVGCVNRIVTELAVIDVCHD-GLHLIETAP-DVSAEEVVAKTQPPLVLD
Mb2531c|M.bovis_AF2122/97 TGVGCVDRIVTELAVIDVCAD-GLHLVQTAP-GVSVDEVVAKTQPPLVLR
Rv2503c|M.tuberculosis_H37Rv TGVGCVDRIVTELAVIDVCAD-GLHLVQTAP-GVSVDEVVAKTQPPLVLR
MAV_4786|M.avium_104 TGKGVVDMIITNLCVFDVEPGRGLLLTELHP-GVTVEEVRAKTGCDFTVA
MSMEG_1899|M.smegmatis_MC2_155 TGKAVVSRVITDLGVFDVTGD-GFRVVELAP-GVEFDHVAANTDATLVDG
Mflv_0525|M.gilvum_PYR-GCK TGLRCVNRVYTDYAVFDIDHTGGGQLRVLHTFGLSIAALEERMRMALSCD
Mvan_0565|M.vanbaalenii_PYR-1 TGLRCVNRVYTDYAVFDIDHTGGGQLRVLHTFGLSIAALEERLRMALSCD
** *. : *: *:*: * : . .: : . :
MMAR_3850|M.marinum_M DLVAR----
MUL_3781|M.ulcerans_Agy99 DLVAR----
Mb2531c|M.bovis_AF2122/97 DLATQ----
Rv2503c|M.tuberculosis_H37Rv DLATQ----
MAV_4786|M.avium_104 L--------
MSMEG_1899|M.smegmatis_MC2_155 RVGSLV---
Mflv_0525|M.gilvum_PYR-GCK GRVADLRQC
Mvan_0565|M.vanbaalenii_PYR-1 GRVADLRQC