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MKKRTLAALVPAAAAAGIAVQDLLQKEHALRRNFPLVARARYLLESIGPELRQYIITSNDAERPFSRDQR RWVYTSAKKENNYFAFGTDNDVENAAYPIIKQATFSDVVPASPIHLRDIEVPGAKVLGAPRGRRHAFRPA SVVNVSAMSFGSLSPQAIEAINKGAKIADFLHNVGEGGLSDHHRQGGELIYQIGTGYFGCRDEHGDFDLA RLVDVVGAAPVRAIEIKLSQGAKPGLGGHLPGAKVNAEIARVRGVERGKDVVSPSRHTAFRNVDEMLDVV ERIADATGLPVGIKSAVGEMGFWQELADRMADGQRGVDFIAIDGGEGGTGAAPLVFADHVSFPFRIGFTR VYGLFAQAGLTDRVTWIGSGKLGLPANAIVAFALGVDLLNVAREAMLAIGCIQAQKCHTDHCPTGVATQN PWLARGLDPEQKSHRLANYVQTLRRDLLKVSEAAGVRHPAMLGPTDVEILDGDRGHRTLAAVYGYQPGWG VPGPEIVAEIDTYMSRYDDRPGTDTVVEHEPLKLATDPNQATE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0988 | - | - | 100% (533) | ferredoxin-dependent glutamate synthase |
| M. gilvum PYR-GCK | Mflv_3593 | - | 2e-33 | 31.17% (324) | glutamate synthase (ferredoxin) |
| M. gilvum PYR-GCK | Mflv_1297 | - | 4e-32 | 29.23% (366) | ferredoxin-dependent glutamate synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3889c | gltB | 2e-29 | 30.41% (296) | putative ferredoxin-dependent glutamate synthase |
| M. tuberculosis H37Rv | Rv3859c | gltB | 2e-29 | 30.41% (296) | ferredoxin-dependent glutamate synthase |
| M. leprae Br4923 | MLBr_00061 | gltB | 7e-30 | 30.77% (299) | putative ferredoxin-dependent glutamate synthase |
| M. abscessus ATCC 19977 | MAB_0091 | - | 5e-29 | 31.10% (299) | putative ferredoxin-dependent glutamate synthase |
| M. marinum M | MMAR_1226 | gltB_1 | 1e-167 | 57.84% (510) | glutamate synthase, GltB_1 |
| M. avium 104 | MAV_0166 | - | 5e-30 | 31.08% (296) | ferredoxin-dependent glutamate synthase 1 |
| M. smegmatis MC2 155 | MSMEG_5594 | - | 1e-44 | 31.15% (427) | ferredoxin-dependent glutamate synthase |
| M. thermoresistible (build 8) | TH_2993 | - | 0.0 | 63.26% (509) | PUTATIVE ferredoxin-dependent glutamate synthase |
| M. ulcerans Agy99 | MUL_2666 | gltB_1 | 1e-166 | 57.65% (510) | glutamate synthase, GltB_1 |
| M. vanbaalenii PYR-1 | Mvan_5847 | - | 0.0 | 88.58% (534) | ferredoxin-dependent glutamate synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3889c|M.bovis_AF2122/97 --MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLNLEHR
Rv3859c|M.tuberculosis_H37Rv --MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLNLEHR
MAV_0166|M.avium_104 MHMTPKRAGLYNPAFEHDACGVAMVVDMHGRRSRDIVDKAITALLNLEHR
MLBr_00061|M.leprae_Br4923 --MTAKRVGLYNPAFEHDSCGVAMVVDMYGRRTRDIVDKAITALLNLEHR
MAB_0091|M.abscessus_ATCC_1997 --MPHPATGLYNPAYEHDSCGVAMVVDMHGRRSRDIVDKAITALLNLEHR
Mflv_0988|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 GAQGAEPRSGDGAGILIQVPDEFLREAVD----FELPAPGSYATGIAFLP
Rv3859c|M.tuberculosis_H37Rv GAQGAEPRSGDGAGILIQVPDEFLREAVD----FELPAPGSYATGIAFLP
MAV_0166|M.avium_104 GAQGAEPRSGDGAGILIQVPDAFLREVVD----FELPPEGSYATGIAFLP
MLBr_00061|M.leprae_Br4923 GAQGAEPRSGDGAGILIQVPDAFLRAVVD----FELPAASSYATGIAFLP
MAB_0091|M.abscessus_ATCC_1997 GAAGAEPNSGDGAGIMLQIPDKFFRAVLAEQGSFELPAEGSYASGIAFLP
Mflv_0988|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 QSSKDAAAACAAVQKIAEAEGLQVLGWRSVPTDDSSLGALSRDAMPTFRQ
Rv3859c|M.tuberculosis_H37Rv QSSKDAAAACAAVQKIAEAEGLQVLGWRSVPTDDSSLGALSRDAMPTFRQ
MAV_0166|M.avium_104 QSSKDAATACAAVEKIAEAEGLTVLGWRNVPTDDSSLGALSRDAMPTFRQ
MLBr_00061|M.leprae_Br4923 QSSKDAAAACAAVEKIAVAEGLHVLGWRNVPTDASSLGALSRDAMPTFRQ
MAB_0091|M.abscessus_ATCC_1997 QGSKDAATACEAVEKIVEAEGLTVLGWREVPHDDSSLGALARDAMPTFRQ
Mflv_0988|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 VFLAGASGMALERRCYVVRKRAEHELGTKGPGQDGPGRETVYFPSLSGQT
Rv3859c|M.tuberculosis_H37Rv VFLAGASGMALERRCYVVRKRAEHELGTKGPGQDGPGRETVYFPSLSGQT
MAV_0166|M.avium_104 VFMAGASGMTLERRAYLVRKRAEHELGTKGPGQDGPGRETVYFPSLSGQT
MLBr_00061|M.leprae_Br4923 VFMAGATGLTLERRAYVIRKRAEHELGTKGPGQDGPGRETIYFPSLSSQT
MAB_0091|M.abscessus_ATCC_1997 LFIAGASGIDLERRVYVVRKRIEHELGNQGSGRGSLGEETVYFPSLSGRT
Mflv_0988|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 LVYKGMLTTPQLKAFYLDLQDERLTSALGIVHSRFSTNTFPSWPLAHPFR
Rv3859c|M.tuberculosis_H37Rv LVYKGMLTTPQLKAFYLDLQDERLTSALGIVHSRFSTNTFPSWPLAHPFR
MAV_0166|M.avium_104 FVYKGMLTTPQLKAFYLDLQDDRLTSALGIVHSRFSTNTFPSWPLAHPFR
MLBr_00061|M.leprae_Br4923 FVYKGMLTTPQLKAFYRDLQDERLTSALGIVHSRFSTNTFPSWPLAHPFR
MAB_0091|M.abscessus_ATCC_1997 FVYKGMLTTPQLRAFYLDLQDERVESALGIVHSRFSTNTFPSWPLAHPYR
Mflv_0988|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 ---------MTLESTARDVQLASLADLPDNTPFAANVAGVDLVLIRRGGD
Mb3889c|M.bovis_AF2122/97 RIAHNGEINTVTGNENWMRAREALIKTDIFGSAADVEKLFPICTPGASDT
Rv3859c|M.tuberculosis_H37Rv RIAHNGEINTVTGNENWMRAREALIKTDIFGSAADVEKLFPICTPGASDT
MAV_0166|M.avium_104 RIAHNGEINTVTGNENWMRAREALIKTDVFGTEADVEKLFPICTPGASDT
MLBr_00061|M.leprae_Br4923 RIAHNGEINTVTGNENWMRAREALMKTDIFGSKADMEKLFPICTPGASDT
MAB_0091|M.abscessus_ATCC_1997 RVAHNGEINTVAGNENWMRAREALIKTDVFGDPAQLEKIFPICTRGASDT
Mflv_0988|M.gilvum_PYR-GCK ------MKKRTLAALVPAAAAAGIAVQDLLQKEHALRRNFPLVAR-----
Mvan_5847|M.vanbaalenii_PYR-1 ------MKKRTLAALAPVAALAGVALQDLLQKEHALRHNFPVIAR-----
TH_2993|M.thermoresistible__bu -----MSSLFRTAAATAASALAAVAVHDVFQRRRAILRNFPVIGH-----
MMAR_1226|M.marinum_M -------MKPRSVAAVLGGGMAGVAGWDLWQRRHAILRNFPIIGH-----
MUL_2666|M.ulcerans_Agy99 -------MKPRSVAAVLGGGMAGVAGWDLWQRRHAILRNFPIIGH-----
MSMEG_5594|M.smegmatis_MC2_155 VKALYGRCAHRGVLLADGHIDGDTVVCDVHGWRYNVETGISPVNP-----
*: : :.
Mb3889c|M.bovis_AF2122/97 ARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPARRAFYQYHASLM
Rv3859c|M.tuberculosis_H37Rv ARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPARRAFYQYHASLM
MAV_0166|M.avium_104 ARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPARRAFYQYHASLM
MLBr_00061|M.leprae_Br4923 ARFDEALELLHLGGRSLVHAVLMMIPEAWERHESMDPARRAFYQYHASLM
MAB_0091|M.abscessus_ATCC_1997 ARFDEALELLHLGGRPLHHAVLMMIPEAWERHENMSAELRSFYEFHASLM
Mflv_0988|M.gilvum_PYR-GCK ---------------------------ARYLLESIGPELRQYIITSNDAE
Mvan_5847|M.vanbaalenii_PYR-1 ---------------------------ARYLLESIGPELRQYIITSNDSE
TH_2993|M.thermoresistible__bu ---------------------------ARYLLESIGPELRQYIVAGDDEE
MMAR_1226|M.marinum_M ---------------------------LRFLLEAVGPELRQYIVTDNNEE
MUL_2666|M.ulcerans_Agy99 ---------------------------LRFLLEAVGPELRQYIVTDNNEE
MSMEG_5594|M.smegmatis_MC2_155 -------------------AVALATFPVQIRDGAVYVDVSAISEFANANP
:
Mb3889c|M.bovis_AF2122/97 EPWDGPASMTFTDGTVVGAVLDRNGLRPSRIWVTDDGLVVMASEAGVLDL
Rv3859c|M.tuberculosis_H37Rv EPWDGPASMTFTDGTVVGAVLDRNGLRPSRIWVTDDGLVVMASEAGVLDL
MAV_0166|M.avium_104 EPWDGPASMTFTDGTVIGAVLDRNGLRPSRIWVTEDGLVVMASEAGVLDL
MLBr_00061|M.leprae_Br4923 EPWDGPASMTFTDGVVVGAVLDRNGLRPSRIWITDAGLVVMASEAGVLDL
MAB_0091|M.abscessus_ATCC_1997 EPWDGPASVCFTDGTIVGAVLDRNGLRPSRVWVTNDGLVVMASEAGVLDL
Mflv_0988|M.gilvum_PYR-GCK RPFS----------------------RDQRRWVYTS--------------
Mvan_5847|M.vanbaalenii_PYR-1 RPFS----------------------RDQRRWVYTS--------------
TH_2993|M.thermoresistible__bu RPFT----------------------RDQRRWVYAS--------------
MMAR_1226|M.marinum_M RPFS----------------------RDQRRWVYTS--------------
MUL_2666|M.ulcerans_Agy99 RPFS----------------------RDQRRWVYTS--------------
MSMEG_5594|M.smegmatis_MC2_155 QPYGDD--------------------GYQGRWATPAN-------------
.*: . *
Mb3889c|M.bovis_AF2122/97 HPSTVVRRMRLQPGRMFLVDTAQGRIVSDEEIKADLAAEHPYQEWLDNGL
Rv3859c|M.tuberculosis_H37Rv HPSTVVRRMRLQPGRMFLVDTAQGRIVSDEEIKADLAAEHPYQEWLDNGL
MAV_0166|M.avium_104 DPATVVRRMRLQPGRMFLVDTAQGRIVSDEEIKAELAAEHPYQEWLDRNL
MLBr_00061|M.leprae_Br4923 DPSIVVRRMRLQPGRMFLVDTAQGRIVSDEEIKAKLAAEHPYQEWLDKGL
MAB_0091|M.abscessus_ATCC_1997 DPSTVVQRTRLQPGRMFLVDTTQGRIVSDEEVKAELAAAEPYQRWLEEGL
Mflv_0988|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 VPLDELPEGKDVRMPHHRIVMRQLAFGYTYEELNLLVAPMARLGAEPIGS
Rv3859c|M.tuberculosis_H37Rv VPLDELPEGKDVRMPHHRIVMRQLAFGYTYEELNLLVAPMARLGAEPIGS
MAV_0166|M.avium_104 VPLDDLPQGDYKRMPHDRLVKRQQTFGYTYEELNLLVAPMVRTGAEPIGS
MLBr_00061|M.leprae_Br4923 VPIDELPAGKYVRMPHHRLVMRQLAFGYTYEELNLLVAPMVRAGSEPIGS
MAB_0091|M.abscessus_ATCC_1997 VRLEQLPDRPHQHMPHNRIVLRQQVFGYTYEEINLLVAPMARTGAEALGS
Mflv_0988|M.gilvum_PYR-GCK -----------------------------------------AKKENNYFA
Mvan_5847|M.vanbaalenii_PYR-1 -----------------------------------------AKKENNYFS
TH_2993|M.thermoresistible__bu -----------------------------------------AKQENNYFS
MMAR_1226|M.marinum_M -----------------------------------------SKLTNRYFG
MUL_2666|M.ulcerans_Agy99 -----------------------------------------SKLTNRYFG
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------TAEEPFNTDIHE
Mb3889c|M.bovis_AF2122/97 MGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPPLDAIREEVVTSLQGTTGG
Rv3859c|M.tuberculosis_H37Rv MGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPPLDAIREEVVTSLQGTTGG
MAV_0166|M.avium_104 MGTDTPVAVLSQRPRMLYDYFQQLFAQVTNPPLDAIREEVVTSLQGTTGG
MLBr_00061|M.leprae_Br4923 MGADTPIAVLSRRPRMLYDYFHQLFAQVTNPPLDAIREEVVTSLQGTTGG
MAB_0091|M.abscessus_ATCC_1997 MGTDTPIAVLSNRSRMLFDYFQQLFAQVTNPPLDAIREEVVTSLGGVIGP
Mflv_0988|M.gilvum_PYR-GCK FGTDNDVEN-AAYPIIKQATFSDVVPAS-PIHLR-DIEVPGAKVLGAPRG
Mvan_5847|M.vanbaalenii_PYR-1 FGTDNDTEN-AAYPIIKQATFSDVVAAS-PIHGR-DIEVPGAKMLGGPRG
TH_2993|M.thermoresistible__bu FGTDNDIEYTSGYPVIRHRTFGRSIPASAPRAAL-DVELPAAKVIGAARN
MMAR_1226|M.marinum_M FGTDNDLERAHNYPIIKHAAFPVSAPDGEPAHPDPAVALPAAKVLGGARG
MUL_2666|M.ulcerans_Agy99 FGTDNDLERAHNYPIIKHAAFPVSAPDGEPAHPDPAVALPAAKVLGGARG
MSMEG_5594|M.smegmatis_MC2_155 LATHGLSRVGKHGPSAAMGVSRTELPSWDSIQLVTAQLARLPLLDQEPVS
:.:. . . . :
Mb3889c|M.bovis_AF2122/97 ERDLLNPDENSCHQIVLPQPILRNHELAKLVSLDPNDKVNGRPHGLRSKV
Rv3859c|M.tuberculosis_H37Rv ERDLLNPDQNSCHQIVLPQPILRNHELAKLVSLDPNDKVNGRPHGLRSKV
MAV_0166|M.avium_104 ERDLLTPTELSCHQIVLSQPILRNRELAKLVNLNPDDEVNGRPHGMRSKV
MLBr_00061|M.leprae_Br4923 EYDLLSPDENSCHQIWLPQPILRNYELAKLVNLDPADEVNGRPHGMRSTV
MAB_0091|M.abscessus_ATCC_1997 EGDLLHPTAESCHQILLPQPVLHNDELDKLIHLDPADTVNGRAHGFSSRV
Mflv_0988|M.gilvum_PYR-GCK RRHAFRP-------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1 RRHAFRP-------------------------------------------
TH_2993|M.thermoresistible__bu RAQAFRP-------------------------------------------
MMAR_1226|M.marinum_M RAKAFRP-------------------------------------------
MUL_2666|M.ulcerans_Agy99 RAKAFRP-------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 TETVIGPG------------------------------------------
: *
Mb3889c|M.bovis_AF2122/97 IRCLYRVSEGGAGLAAALEEVRGAAAAAIADGARIIILSDRESDEEMAPI
Rv3859c|M.tuberculosis_H37Rv IRCLYRVSEGGAGLAAALEEVRGAAAAAIADGARIIILSDRESDEEMAPI
MAV_0166|M.avium_104 IRCLYPVAEGGAGLAAALEDVRAQASAAIADGARVIILSDRESDEKMAPI
MLBr_00061|M.leprae_Br4923 VSCLYPVADAGAGLAAALTEVRAQASAAIVGGARVIILSDRNSDEQMAPI
MAB_0091|M.abscessus_ATCC_1997 IRCLYPVAEGGAGLRTALESVRAEVSAAIAGGAQVIILSDRESDDLMAPI
Mflv_0988|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 PSLLAVAGVHHHLVRERTRTQVGLVVESGDAREVHHMAALVGFGAAAINP
Rv3859c|M.tuberculosis_H37Rv PSLLAVAGVHHHLVRERTRTQVGLVVESGDAREVHHMAALVGFGAAAINP
MAV_0166|M.avium_104 PSLLAVAGVHHHLVRDRTRTHVGLVVESGDAREVHHMAALVGFGAAAINP
MLBr_00061|M.leprae_Br4923 PSLLSVAAVHHHLVRDRTRTHVGLVVESGDAREVHHMAALIGFGAAAVNP
MAB_0091|M.abscessus_ATCC_1997 PSLLAVAAVHHHLVRERSRTKVGLVVEAGDAREVHHVAALVGFGAAAVNP
Mflv_0988|M.gilvum_PYR-GCK -------------------------------------ASVVNVSAMSFG-
Mvan_5847|M.vanbaalenii_PYR-1 -------------------------------------ASVVNVSAMSFG-
TH_2993|M.thermoresistible__bu -------------------------------------QSVVNIGAMSFG-
MMAR_1226|M.marinum_M -------------------------------------SSLVNISGMSYG-
MUL_2666|M.ulcerans_Agy99 -------------------------------------SSLVNISGMSYG-
MSMEG_5594|M.smegmatis_MC2_155 ------------------------------AKRPLVLDIPLFVSDMSFG-
: .. : .
Mb3889c|M.bovis_AF2122/97 YLVFESIEDMLDRGVIEGIDRTAALNNYIKAAGKGVLKVMSKMGISTLAS
Rv3859c|M.tuberculosis_H37Rv YLVFESIEDMLDRGVIEGIDRTAALNNYIKAAGKGVLKVMSKMGISTLAS
MAV_0166|M.avium_104 YMVFESIEDMLDRGVIEGIDRNTALNNYVKAAGKGVLKVMSKMGISTLAS
MLBr_00061|M.leprae_Br4923 YLVFESIEEMLDRGVIDGIDRKTALNNYIKATGQGVLKIMSKMGISTLAS
MAB_0091|M.abscessus_ATCC_1997 YMAFESIEDLIDRGVITGVDRDKAIRNYIKAAGKGVLKVMSKMGISTLAS
Mflv_0988|M.gilvum_PYR-GCK ---------SLSPQAIEAINKGAKIADFLHNVGEGGLSDHHRQ-------
Mvan_5847|M.vanbaalenii_PYR-1 ---------SLSPQAIEAINKGAKIADFWHNTGEGGLSDHHRQ-------
TH_2993|M.thermoresistible__bu ---------SLSGKAIEALNRGAALAGCLHNTGEGGISRYHRH-------
MMAR_1226|M.marinum_M ---------ALGGAAISALNQGAAIAGALHTTGEGAVSPYHLN-------
MUL_2666|M.ulcerans_Agy99 ---------ALGGAAISALNQGAGIAGALHTTGEGAVSPYHLN-------
MSMEG_5594|M.smegmatis_MC2_155 ---------ALSEEAKTALAAGAELAGTGICSGEGGMLPEEQQ-------
:. . .: : . *:* :
Mb3889c|M.bovis_AF2122/97 YTGAQLFQAVGISEQVLDEYFTGLTCPTGGITLDDIAADVAARHRLAYLD
Rv3859c|M.tuberculosis_H37Rv YTGAQLFQAVGISEQVLDEYFTGLTCPTGGITLDDIAADVAARHRLAYLD
MAV_0166|M.avium_104 YTGAQLFQAVGISEDVLDEYFTGLSCPIGGITLDDIAADVAARHALAYLD
MLBr_00061|M.leprae_Br4923 YVGAQLFQAVGISEDVLDEYFSGLSCPTGGITLDDIAAEVAVRHRVAYLD
MAB_0091|M.abscessus_ATCC_1997 YTGAQLFQAIGLSQELLDEYFTGLACPTGGIGLDEIAADVASRHNLAFLD
Mflv_0988|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 RPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHSTRTGQYKIFKEY
Rv3859c|M.tuberculosis_H37Rv RPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHSTRTGQYKIFKEY
MAV_0166|M.avium_104 RPNERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHATRTGQYKIFKDY
MLBr_00061|M.leprae_Br4923 RPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHATRSGQYKIFKEY
MAB_0091|M.abscessus_ATCC_1997 RPEEWAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHSTRTGQYSVFKEY
Mflv_0988|M.gilvum_PYR-GCK ------------GGELIYQ-------------------------------
Mvan_5847|M.vanbaalenii_PYR-1 ------------GGDLVYQ-------------------------------
TH_2993|M.thermoresistible__bu ------------GGELIFQ-------------------------------
MMAR_1226|M.marinum_M ------------GGDLVWQ-------------------------------
MUL_2666|M.ulcerans_Agy99 ------------GGDLVWQ-------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 TRLVDDQSERMASLRGLLKFRTGVRPPVPLDEVEPASEIVKRFSTGAMSY
Rv3859c|M.tuberculosis_H37Rv TRLVDDQSERMASLRGLLKFRTGVRPPVPLDEVEPASEIVKRFSTGAMSY
MAV_0166|M.avium_104 TRLVDDQSERMASLRGLLKFRAGVRPPVPLEEVEPASEIVKRFSTGAMSY
MLBr_00061|M.leprae_Br4923 TRLVDDQSERMASLRGLLKFRSGVRTPVPLDEVEPASEIVKRFSTGAMSY
MAB_0091|M.abscessus_ATCC_1997 TQLVDDQSERMASLRGLLKFKTGVRPPVPLDEVEPASEIVKRFSTGAMSF
Mflv_0988|M.gilvum_PYR-GCK --------------------------------------------IGTGYF
Mvan_5847|M.vanbaalenii_PYR-1 --------------------------------------------IGTGYF
TH_2993|M.thermoresistible__bu --------------------------------------------IGTAYF
MMAR_1226|M.marinum_M --------------------------------------------IGTGYF
MUL_2666|M.ulcerans_Agy99 --------------------------------------------IGTGYF
MSMEG_5594|M.smegmatis_MC2_155 -------------------------------------------ENSRYFY
. :
Mb3889c|M.bovis_AF2122/97 GSISAEAHETLAIAMNRLGARSNCGEGGEDVKRFDRDPNGDWRRSAIKQV
Rv3859c|M.tuberculosis_H37Rv GSISAEAHETLAIAMNRLGARSNCGEGGEDVKRFDRDPNGDWRRSAIKQV
MAV_0166|M.avium_104 GSISAEAHETLAIAMNRLGGRSNSGEGGEDVKRFDRDPDGSWRRSAIKQV
MLBr_00061|M.leprae_Br4923 GSISAEAHETLAIAMNRLGGRSNSGEGGEDVNRFEPDPNGDWRRSAIKQV
MAB_0091|M.abscessus_ATCC_1997 GSISAEAHETLAIAMNRLGGRSNSGEGGEDPRRFTPDENGDWRRSAIKQV
Mflv_0988|M.gilvum_PYR-GCK GCRDEHGDFDLARLVDVVGAAP----------------------------
Mvan_5847|M.vanbaalenii_PYR-1 GCRDEHGNFDLDRLVDVVGSGP----------------------------
TH_2993|M.thermoresistible__bu GCRDAEGRFDLARLKDLVAGAP----------------------------
MMAR_1226|M.marinum_M GCRNDDGTFSLSRLIDRVAATPS---------------------------
MUL_2666|M.ulcerans_Agy99 GCRNDDGTFSLSRLIDRVAATTS---------------------------
MSMEG_5594|M.smegmatis_MC2_155 ELASGRFGWSFEHLHK----------------------------------
. : .
Mb3889c|M.bovis_AF2122/97 ASARFGVTSHYLTNCTDLQIKMAQGAKPGEGGQLPGHKVYPWVAEVRHST
Rv3859c|M.tuberculosis_H37Rv ASARFGVTSHYLTNCTDLQIKMAQGAKPGEGGQLPGHKVYPWVAEVRHST
MAV_0166|M.avium_104 ASGRFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGHKVYPWVAEVRHST
MLBr_00061|M.leprae_Br4923 ASARFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGRKVYPWIAQVRNST
MAB_0091|M.abscessus_ATCC_1997 ASGRFGVTSHYLSNCTDIQIKMAQGAKPGEGGQLPAHKVYPWVAEVRHST
Mflv_0988|M.gilvum_PYR-GCK --------------VRAIEIKLSQGAKPGLGGHLPGAKVNAEIARVRGVE
Mvan_5847|M.vanbaalenii_PYR-1 --------------VRAIEIKLSQGAKPGLGGHLPGAKVNAEIARIRGVE
TH_2993|M.thermoresistible__bu --------------VRALEIKLSQGAKPTLGGVLPAAKVSAEIAATRGIP
MMAR_1226|M.marinum_M --------------IRAIEIKLSQGAKPGLGGMLPGAKVTADIAAIRGIP
MUL_2666|M.ulcerans_Agy99 --------------IRAIEIKLSQGAKPGLGGMLPGAKVTADIAAIRGIP
MSMEG_5594|M.smegmatis_MC2_155 --------------VQAFHFKGGQGAKTGTGGHLPGSKVVGKIADVRGLP
:.:* .****. ** **. ** :* *
Mb3889c|M.bovis_AF2122/97 PGVGLISPPPHHDIYSIEDLAQLIHDLKNANP-SARVHVKLVSE----NG
Rv3859c|M.tuberculosis_H37Rv PGVGLISPPPHHDIYSIEDLAQLIHDLKNANP-SARVHVKLVSE----NG
MAV_0166|M.avium_104 PGVGLISPPPHHDIYSIEDLAQLIHDLKNANP-AARVHVKLVSE----NG
MLBr_00061|M.leprae_Br4923 PGVGLISPPPHHDIYSIEDLAQLIHDLKNANP-SARVHVKLVSE----NG
MAB_0091|M.abscessus_ATCC_1997 PGVGLISPPPHHDIYSIEDLAQLIHDLKNSNP-QARIHVKLVSE----NG
Mflv_0988|M.gilvum_PYR-GCK RGKDVVSPSRHTAFRNVDEMLDVVERIADATG-LPVGIKSAVGEMGFWQE
Mvan_5847|M.vanbaalenii_PYR-1 QGKDVASPSRHTAFRDVDEMLDLVERIADATG-LPVGIKSAVGELDFWQT
TH_2993|M.thermoresistible__bu EGRDCVSPSRHAEFTDADSMLDWVEMLAAETG-LPVGIKSAVGDLDFWEQ
MMAR_1226|M.marinum_M VGVDCKSPAGHSAFADIDGMLELVETIADATG-LPVGIKSAVGEGLFWPQ
MUL_2666|M.ulcerans_Agy99 VGVDCKSPAGHSAFADIDGMLELVETIADATG-LPVGIKSAVGEGLFWPQ
MSMEG_5594|M.smegmatis_MC2_155 PGTSAISPARFPDWTSLAEYRDFAAQVRDISGGIPVGYKLSAQH------
* . **. . . : : . . . .
Mb3889c|M.bovis_AF2122/97 VGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGLAETQQT
Rv3859c|M.tuberculosis_H37Rv VGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGLAETQQT
MAV_0166|M.avium_104 VGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGLAETQQT
MLBr_00061|M.leprae_Br4923 VGTVAAGVSKAHADVVLVSGHDGGTGATPLTSMKHSGAPWELGLAETQQT
MAB_0091|M.abscessus_ATCC_1997 VGTVATGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGLAETQQT
Mflv_0988|M.gilvum_PYR-GCK LADRMAD-GQRGVDFIAIDGGEGGTGAAPLVFADHVSFPFRIGFTRVYGL
Mvan_5847|M.vanbaalenii_PYR-1 LADRMDDDGQRGVDFITIDGGEGGTGAAPLVFADHVSFPFRMGFARVYGL
TH_2993|M.thermoresistible__bu LTDLMRD-TGRGVDFVSIDGGEGGTGAAPLIFTDTVSLPFQLGFAEVYRI
MMAR_1226|M.marinum_M LAARMAR-TGRGVDFVTVDGGEGGTGAAPLVFSDHVALPFKWAFPRVFRA
MUL_2666|M.ulcerans_Agy99 LAARMAR-TGRGVDFVTVDGGEGGTGAAPLVFSDHVALPFKWAFPRVFRA
MSMEG_5594|M.smegmatis_MC2_155 IERDLDAALEIGVDYVILDGRGGGTGSAPTIFPRHISVPTIPALARARRH
: .* : :.* ****::* . * .:...
Mb3889c|M.bovis_AF2122/97 LLLNGLRDRIVVQVDGQLKTGRDVMIATLLGAEEFGFATAPLVVAGCIMM
Rv3859c|M.tuberculosis_H37Rv LLLNGLRDRIVVQVDGQLKTGRDVMIATLLGAEEFGFATAPLVVAGCIMM
MAV_0166|M.avium_104 LLLNGLRDRIVVQVDGQLKTGRDVMIAALLGAEEFGFATAPLVVSGCIMM
MLBr_00061|M.leprae_Br4923 LLLNGLRDRIVVQVDGQLKTGRDVMIAALLGAEEFGFATAPLVVAGCIMM
MAB_0091|M.abscessus_ATCC_1997 LLLNGLRDRIVVQVDGQLKTGRDVMIAMLLGGEEFGFATAPLVVSGCIMM
Mflv_0988|M.gilvum_PYR-GCK FAQAGLTDRVTWIGSGKLGLPANAIVAFALGVDLLNVAREAMLAIGCIQA
Mvan_5847|M.vanbaalenii_PYR-1 FAERGLTDRVTWIGSAKLGLPANAIVAFALGVDLINVAREAMFAIGCIQA
TH_2993|M.thermoresistible__bu FAERGLHEQVTFIGSGKLGLPDNAVVAFALGCDMVYAARESMLALGCIQA
MMAR_1226|M.marinum_M FAEEDLHHDVVFIGSAKLGIPENALLALTMGVDMINVGRTAMFAIGCIQA
MUL_2666|M.ulcerans_Agy99 FAEEDLHHDVVFIGSAKLGIPENALLALAMGADMINVGRTAMFAIGCIQA
MSMEG_5594|M.smegmatis_MC2_155 LDRS--ESRITLAVTGGIRTPADMVKALALGADAIGVANSAIQAIGCVGM
: :. . : : : * :* : . . .: . **:
Mb3889c|M.bovis_AF2122/97 RVCHLDTCPVGVATQNPLLRERFTGKPEFVENFFMFIAEEVREYLAQLGF
Rv3859c|M.tuberculosis_H37Rv RVCHLDTCPVGVATQNPLLRERFTGKPEFVENFFMFIAEEVREYLAQLGF
MAV_0166|M.avium_104 RVCHLDTCPVGVATQNPVLRERFTGKPEFVENFFMFIAEEVREYMAQLGF
MLBr_00061|M.leprae_Br4923 RVCHLDTCPVGVATQNPLLRKRFNGKPEFVENFFMFIAEEVREYMAQLGF
MAB_0091|M.abscessus_ATCC_1997 RVCHLDTCPVGVATQNPVLRQRFNGKPEFVENFFLFIAEEVRELMAELGF
Mflv_0988|M.gilvum_PYR-GCK QKCHTDHCPTGVATQNPWLARGLDPEQ---------KSHRLANYVQTLRR
Mvan_5847|M.vanbaalenii_PYR-1 QKCHTDRCPTGVATQNAWLARGLDPEQ---------KSHRLANYVMTLRR
TH_2993|M.thermoresistible__bu KKCHTDTCPTGVATQNAWLTRGLVPDD---------KAPRVANYIRTLRR
MMAR_1226|M.marinum_M QRCHTGRCPSGVATQSAWLQHGLDPAL---------KAVRCANYLATLRF
MUL_2666|M.ulcerans_Agy99 QRCHTGRCPSGVATQSAWLQHGLDPAL---------KAVRCANYLATLRF
MSMEG_5594|M.smegmatis_MC2_155 RACHTNACPAGIATQDPHLRARLPVRQ---------AAERLNRYLRSAVD
: ** . ** *:***.. * : : . . :
Mb3889c|M.bovis_AF2122/97 RTVNEAVGQAGALDTTLARAHWKAHKLDLAPVLHEPESAFMNQDLYCSSR
Rv3859c|M.tuberculosis_H37Rv RTVNEAVGQAGALDTTLARAHWKAHKLDLAPVLHEPESAFMNQDLYCSSR
MAV_0166|M.avium_104 RTLNEAVGQVKSLDTTLARAHWKAHRLDLGPVLHEPESAFMNQDLYCSSR
MLBr_00061|M.leprae_Br4923 RTFNEAVGQVGALDTTPVREHWKAHSIDLTPVLHEPESAFMNQDLYCSSR
MAB_0091|M.abscessus_ATCC_1997 RTVNEAVGQVGALDIERAVAHWKASKIDLTPVLTEPESAFMNQDLYCSGS
Mflv_0988|M.gilvum_PYR-GCK DLLKVSEAAGVRHPAMLGPTDVEILDGDRGHRTLAAVYGYQPGWGVPGPE
Mvan_5847|M.vanbaalenii_PYR-1 DLLKVSEAAGVRHPAMLSPKHVEILDGDRGHRPLADVYGYQEWWGTPGPE
TH_2993|M.thermoresistible__bu DLVKVAEACGVEHPGLISGDLIDILDGHTSARSLYEVYGYQPGMGLPSAE
MMAR_1226|M.marinum_M ELLSLARACGYVHPALVPLQAIELLDVDLQTVQVDDLFGYQPGWGIPSPA
MUL_2666|M.ulcerans_Agy99 ELLSLARACGYVHPALVPLQAIELLDVDLQTVQVDDLFGYQPGWGIPSPA
MSMEG_5594|M.smegmatis_MC2_155 LMVVLARACGHHRLAEFTLDDLTTFDRDFAYLSGVPYGGVTPL-------
. : . . .
Mb3889c|M.bovis_AF2122/97 QDHGLDKALDQQLIVMSREALDSGKPVRFSTTIGNVNRTVGTMLGHELTK
Rv3859c|M.tuberculosis_H37Rv QDHGLDKALDQQLIVMSREALDSGKPVRFSTTIGNVNRTVGTMLGHELTK
MAV_0166|M.avium_104 QDHGLDKALDQQLIVMSREALDSGKPVRFSTTISNVNRTVGTMLGHEVTK
MLBr_00061|M.leprae_Br4923 QDHGLDKVLDQQLIAVSRDALDFGKPVRFSTTIGNVNRTVGTMLGHELTK
MAB_0091|M.abscessus_ATCC_1997 QDHGLEKALDQQLIVMSREALDHGTPVKFETLITNVNRTVGTMLGHEVTK
Mflv_0988|M.gilvum_PYR-GCK IVAEIDTYMSRYDDRPGTDTVVEHEPLKLATDPNQATE------------
Mvan_5847|M.vanbaalenii_PYR-1 IVDEIDAYMRRYDDLPGTHEVVEHEPLKVAAEPNQATE------------
TH_2993|M.thermoresistible__bu DRAEILRLMADRATRGGSAPPSHSAPAR----------------------
MMAR_1226|M.marinum_M DVAAITALMTKAS------------PPR----------------------
MUL_2666|M.ulcerans_Agy99 DVAAITALMTKAS------------PPR----------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 AYGGQGLPDGTIDITFDGSAGNSFGAFVPKGITLRVYGDANDYVGKGLSG
Rv3859c|M.tuberculosis_H37Rv AYGGQGLPDGTIDITFDGSAGNSFGAFVPKGITLRVYGDANDYVGKGLSG
MAV_0166|M.avium_104 AYGGQGLPDGTIDITFDGSAGNSFGAFVPRGITLRVYGDANDYVGKGLSG
MLBr_00061|M.leprae_Br4923 AYGAQGLPDGTIDITFEGSAGNSFGAFVPKGITLRVYGDANDYVGKGLSG
MAB_0091|M.abscessus_ATCC_1997 AYGGEGLPDDTIDITFTGSAGNSFGAFVPRGITLRLFGDANDYVGKGLSG
Mflv_0988|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 GRIVVRPSDDAPQDYVAEDNIIGGNVILFGATSGEVYLRGVVGERFAVRN
Rv3859c|M.tuberculosis_H37Rv GRIVVRPSDDAPQDYVAEDNIIGGNVILFGATSGEVYLRGVVGERFAVRN
MAV_0166|M.avium_104 GRIVVRPSDNAPADYVAEDNIIGGNVILFGATSGEAYLRGVVGERFAVRN
MLBr_00061|M.leprae_Br4923 GRIVVRPSDSVPLNYVAEDNIIGGNVILFGATSGEVYLRGVVGERFAVRN
MAB_0091|M.abscessus_ATCC_1997 GHIVVRPSREAPEGFVAEKNIIGGNVILFGATSGEAFLNGVVGERFAVRN
Mflv_0988|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 SGAHAVVEGVGDHGCEYMTGGRVVILGRTGRNFAAGMSGGVAYVYDPDGE
Rv3859c|M.tuberculosis_H37Rv SGAHAVVEGVGDHGCEYMTGGRVVILGRTGRNFAAGMSGGVAYVYDPDGE
MAV_0166|M.avium_104 SGAHAVVEGVGDHGCEYMTGGKVVVLGRTGRNFAAGMSGGVAYIYDPPGE
MLBr_00061|M.leprae_Br4923 SGAHAVVEGVGDHGCEYMTGGKVVILGRTGRNFAAGMSGGEAYVYDSDGE
MAB_0091|M.abscessus_ATCC_1997 SGAAAVVEGVGDHGCEYMTGGTVVVLGPTGRNFAAGMSGGVAYVYDPDKR
Mflv_0988|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 LPANLNSEMVELETLDEDDADWLHGTIQVHVDATDSAVGQRILSDWSGQQ
Rv3859c|M.tuberculosis_H37Rv LPANLNSEMVELETLDEDDADWLHGTIQVHVDATDSAVGQRILSDWSGQQ
MAV_0166|M.avium_104 FPQHLNAEMVELESLDDDDIEWLHGMIQAHVDATDSAVGQRILGDWAQQQ
MLBr_00061|M.leprae_Br4923 LPANLNFEMVELEPLDFDDAAWLYATIQAHVDATDSAVGQRILAGWSEQQ
MAB_0091|M.abscessus_ATCC_1997 LMDNLNDEMVDLDALDPDDQQVLRSLIEKHVAATDSAVGQRILADWSGHS
Mflv_0988|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 RHFVKVMPRDYKRVLQAIALAERDGVDVDKAIMAAAHG
Rv3859c|M.tuberculosis_H37Rv RHFVKVMPRDYKRVLQAIALAERDGVDVDKAIMAAAHG
MAV_0166|M.avium_104 RHFVKVMPRDYKRVLQAIAEAERDGGDVDKAIMAAAHG
MLBr_00061|M.leprae_Br4923 RYFVKVMPKDYKRVLQAIALAERNGVDVNKVIMEPAHG
MAB_0091|M.abscessus_ATCC_1997 DSFVKVMPRDYRRVLEAIADAELTGGDVNEAIMAAARG
Mflv_0988|M.gilvum_PYR-GCK --------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1 --------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------
MMAR_1226|M.marinum_M --------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------