For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TLESTARDVQLASLADLPDNTPFAANVAGVDLVLIRRGGDVKALYGRCAHRGVLLADGHIDGDTVVCDVH GWRYNVETGISPVNPAVALATFPVQIRDGAVYVDVSAISEFANANPQPYGDDGYQGRWATPANTAEEPFN TDIHELATHGLSRVGKHGPSAAMGVSRTELPSWDSIQLVTAQLARLPLLDQEPVSTETVIGPGAKRPLVL DIPLFVSDMSFGALSEEAKTALAAGAELAGTGICSGEGGMLPEEQQENSRYFYELASGRFGWSFEHLHKV QAFHFKGGQGAKTGTGGHLPGSKVVGKIADVRGLPPGTSAISPARFPDWTSLAEYRDFAAQVRDISGGIP VGYKLSAQHIERDLDAALEIGVDYVILDGRGGGTGSAPTIFPRHISVPTIPALARARRHLDRSESRITLA VTGGIRTPADMVKALALGADAIGVANSAIQAIGCVGMRACHTNACPAGIATQDPHLRARLPVRQAAERLN RYLRSAVDLMVVLARACGHHRLAEFTLDDLTTFDRDFAYLSGVPYGGVTPL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5594 | - | - | 100% (542) | ferredoxin-dependent glutamate synthase |
| M. smegmatis MC2 155 | MSMEG_6263 | - | 3e-57 | 33.56% (432) | glutamate synthase family protein |
| M. smegmatis MC2 155 | MSMEG_3225 | - | 5e-36 | 33.66% (309) | ferredoxin-dependent glutamate synthase 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3889c | gltB | 3e-32 | 32.59% (270) | putative ferredoxin-dependent glutamate synthase |
| M. gilvum PYR-GCK | Mflv_1297 | - | 3e-56 | 34.74% (403) | ferredoxin-dependent glutamate synthase |
| M. tuberculosis H37Rv | Rv3859c | gltB | 3e-32 | 32.59% (270) | ferredoxin-dependent glutamate synthase |
| M. leprae Br4923 | MLBr_00061 | gltB | 5e-33 | 33.70% (270) | putative ferredoxin-dependent glutamate synthase |
| M. abscessus ATCC 19977 | MAB_0091 | - | 2e-33 | 33.94% (274) | putative ferredoxin-dependent glutamate synthase |
| M. marinum M | MMAR_1226 | gltB_1 | 2e-37 | 32.83% (332) | glutamate synthase, GltB_1 |
| M. avium 104 | MAV_0166 | - | 5e-33 | 33.58% (271) | ferredoxin-dependent glutamate synthase 1 |
| M. thermoresistible (build 8) | TH_2993 | - | 4e-37 | 32.91% (313) | PUTATIVE ferredoxin-dependent glutamate synthase |
| M. ulcerans Agy99 | MUL_2666 | gltB_1 | 2e-38 | 33.43% (332) | glutamate synthase, GltB_1 |
| M. vanbaalenii PYR-1 | Mvan_5512 | - | 1e-58 | 35.88% (393) | ferredoxin-dependent glutamate synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3889c|M.bovis_AF2122/97 --MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLNLEHR
Rv3859c|M.tuberculosis_H37Rv --MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLNLEHR
MAV_0166|M.avium_104 MHMTPKRAGLYNPAFEHDACGVAMVVDMHGRRSRDIVDKAITALLNLEHR
MLBr_00061|M.leprae_Br4923 --MTAKRVGLYNPAFEHDSCGVAMVVDMYGRRTRDIVDKAITALLNLEHR
MAB_0091|M.abscessus_ATCC_1997 --MPHPATGLYNPAYEHDSCGVAMVVDMHGRRSRDIVDKAITALLNLEHR
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 GAQGAEPRSGDGAGILIQVPDEFLREAVD----FELPAPGSYATGIAFLP
Rv3859c|M.tuberculosis_H37Rv GAQGAEPRSGDGAGILIQVPDEFLREAVD----FELPAPGSYATGIAFLP
MAV_0166|M.avium_104 GAQGAEPRSGDGAGILIQVPDAFLREVVD----FELPPEGSYATGIAFLP
MLBr_00061|M.leprae_Br4923 GAQGAEPRSGDGAGILIQVPDAFLRAVVD----FELPAASSYATGIAFLP
MAB_0091|M.abscessus_ATCC_1997 GAAGAEPNSGDGAGIMLQIPDKFFRAVLAEQGSFELPAEGSYASGIAFLP
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 QSSKDAAAACAAVQKIAEAEGLQVLGWRSVPTDDSSLGALSRDAMPTFRQ
Rv3859c|M.tuberculosis_H37Rv QSSKDAAAACAAVQKIAEAEGLQVLGWRSVPTDDSSLGALSRDAMPTFRQ
MAV_0166|M.avium_104 QSSKDAATACAAVEKIAEAEGLTVLGWRNVPTDDSSLGALSRDAMPTFRQ
MLBr_00061|M.leprae_Br4923 QSSKDAAAACAAVEKIAVAEGLHVLGWRNVPTDASSLGALSRDAMPTFRQ
MAB_0091|M.abscessus_ATCC_1997 QGSKDAATACEAVEKIVEAEGLTVLGWREVPHDDSSLGALARDAMPTFRQ
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 VFLAGASGMALERRCYVVRKRAEHELGTKGPGQDGPGRETVYFPSLSGQT
Rv3859c|M.tuberculosis_H37Rv VFLAGASGMALERRCYVVRKRAEHELGTKGPGQDGPGRETVYFPSLSGQT
MAV_0166|M.avium_104 VFMAGASGMTLERRAYLVRKRAEHELGTKGPGQDGPGRETVYFPSLSGQT
MLBr_00061|M.leprae_Br4923 VFMAGATGLTLERRAYVIRKRAEHELGTKGPGQDGPGRETIYFPSLSSQT
MAB_0091|M.abscessus_ATCC_1997 LFIAGASGIDLERRVYVVRKRIEHELGNQGSGRGSLGEETVYFPSLSGRT
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 LVYKGMLTTPQLKAFYLDLQDERLTSALGIVHSRFSTNTFPSWPLAHPFR
Rv3859c|M.tuberculosis_H37Rv LVYKGMLTTPQLKAFYLDLQDERLTSALGIVHSRFSTNTFPSWPLAHPFR
MAV_0166|M.avium_104 FVYKGMLTTPQLKAFYLDLQDDRLTSALGIVHSRFSTNTFPSWPLAHPFR
MLBr_00061|M.leprae_Br4923 FVYKGMLTTPQLKAFYRDLQDERLTSALGIVHSRFSTNTFPSWPLAHPFR
MAB_0091|M.abscessus_ATCC_1997 FVYKGMLTTPQLRAFYLDLQDERVESALGIVHSRFSTNTFPSWPLAHPYR
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 RIAHNGEINTVTGNENWMRAREALIKTDIFGSAADVEKLFPICTPGASDT
Rv3859c|M.tuberculosis_H37Rv RIAHNGEINTVTGNENWMRAREALIKTDIFGSAADVEKLFPICTPGASDT
MAV_0166|M.avium_104 RIAHNGEINTVTGNENWMRAREALIKTDVFGTEADVEKLFPICTPGASDT
MLBr_00061|M.leprae_Br4923 RIAHNGEINTVTGNENWMRAREALMKTDIFGSKADMEKLFPICTPGASDT
MAB_0091|M.abscessus_ATCC_1997 RVAHNGEINTVAGNENWMRAREALIKTDVFGDPAQLEKIFPICTRGASDT
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 ARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPARRAFYQYHASLM
Rv3859c|M.tuberculosis_H37Rv ARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPARRAFYQYHASLM
MAV_0166|M.avium_104 ARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPARRAFYQYHASLM
MLBr_00061|M.leprae_Br4923 ARFDEALELLHLGGRSLVHAVLMMIPEAWERHESMDPARRAFYQYHASLM
MAB_0091|M.abscessus_ATCC_1997 ARFDEALELLHLGGRPLHHAVLMMIPEAWERHENMSAELRSFYEFHASLM
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 EPWDGPASMTFTDGTVVGAVLDRNGLRPSRIWVTDDGLVVMASEAGVLDL
Rv3859c|M.tuberculosis_H37Rv EPWDGPASMTFTDGTVVGAVLDRNGLRPSRIWVTDDGLVVMASEAGVLDL
MAV_0166|M.avium_104 EPWDGPASMTFTDGTVIGAVLDRNGLRPSRIWVTEDGLVVMASEAGVLDL
MLBr_00061|M.leprae_Br4923 EPWDGPASMTFTDGVVVGAVLDRNGLRPSRIWITDAGLVVMASEAGVLDL
MAB_0091|M.abscessus_ATCC_1997 EPWDGPASVCFTDGTIVGAVLDRNGLRPSRVWVTNDGLVVMASEAGVLDL
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 HPSTVVRRMRLQPGRMFLVDTAQGRIVSDEEIKADLAAEHPYQEWLDNGL
Rv3859c|M.tuberculosis_H37Rv HPSTVVRRMRLQPGRMFLVDTAQGRIVSDEEIKADLAAEHPYQEWLDNGL
MAV_0166|M.avium_104 DPATVVRRMRLQPGRMFLVDTAQGRIVSDEEIKAELAAEHPYQEWLDRNL
MLBr_00061|M.leprae_Br4923 DPSIVVRRMRLQPGRMFLVDTAQGRIVSDEEIKAKLAAEHPYQEWLDKGL
MAB_0091|M.abscessus_ATCC_1997 DPSTVVQRTRLQPGRMFLVDTTQGRIVSDEEVKAELAAAEPYQRWLEEGL
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 VPLDELPEGKDVRMPHHRIVMRQLAFGYTYEELNLLVAPMARLGAEPIGS
Rv3859c|M.tuberculosis_H37Rv VPLDELPEGKDVRMPHHRIVMRQLAFGYTYEELNLLVAPMARLGAEPIGS
MAV_0166|M.avium_104 VPLDDLPQGDYKRMPHDRLVKRQQTFGYTYEELNLLVAPMVRTGAEPIGS
MLBr_00061|M.leprae_Br4923 VPIDELPAGKYVRMPHHRLVMRQLAFGYTYEELNLLVAPMVRAGSEPIGS
MAB_0091|M.abscessus_ATCC_1997 VRLEQLPDRPHQHMPHNRIVLRQQVFGYTYEEINLLVAPMARTGAEALGS
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 MGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPPLDAIREEVVTSLQGTTGG
Rv3859c|M.tuberculosis_H37Rv MGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPPLDAIREEVVTSLQGTTGG
MAV_0166|M.avium_104 MGTDTPVAVLSQRPRMLYDYFQQLFAQVTNPPLDAIREEVVTSLQGTTGG
MLBr_00061|M.leprae_Br4923 MGADTPIAVLSRRPRMLYDYFHQLFAQVTNPPLDAIREEVVTSLQGTTGG
MAB_0091|M.abscessus_ATCC_1997 MGTDTPIAVLSNRSRMLFDYFQQLFAQVTNPPLDAIREEVVTSLGGVIGP
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 ERDLLNPDENSCHQIVLPQPILRNHELAKLVSLDPNDKVNGRPHGLRSKV
Rv3859c|M.tuberculosis_H37Rv ERDLLNPDQNSCHQIVLPQPILRNHELAKLVSLDPNDKVNGRPHGLRSKV
MAV_0166|M.avium_104 ERDLLTPTELSCHQIVLSQPILRNRELAKLVNLNPDDEVNGRPHGMRSKV
MLBr_00061|M.leprae_Br4923 EYDLLSPDENSCHQIWLPQPILRNYELAKLVNLDPADEVNGRPHGMRSTV
MAB_0091|M.abscessus_ATCC_1997 EGDLLHPTAESCHQILLPQPVLHNDELDKLIHLDPADTVNGRAHGFSSRV
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 IRCLYRVSEGGAGLAAALEEVRGAAAAAIADGARIIILSDRESDEEMAPI
Rv3859c|M.tuberculosis_H37Rv IRCLYRVSEGGAGLAAALEEVRGAAAAAIADGARIIILSDRESDEEMAPI
MAV_0166|M.avium_104 IRCLYPVAEGGAGLAAALEDVRAQASAAIADGARVIILSDRESDEKMAPI
MLBr_00061|M.leprae_Br4923 VSCLYPVADAGAGLAAALTEVRAQASAAIVGGARVIILSDRNSDEQMAPI
MAB_0091|M.abscessus_ATCC_1997 IRCLYPVAEGGAGLRTALESVRAEVSAAIAGGAQVIILSDRESDDLMAPI
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------MTLESTARDVQLASLADLPDNTPFAANVAGVDLVLI
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 PSLLAVAGVHHHLVRERTRTQVGLVVESGDAREVHHMAALVGFGAAAINP
Rv3859c|M.tuberculosis_H37Rv PSLLAVAGVHHHLVRERTRTQVGLVVESGDAREVHHMAALVGFGAAAINP
MAV_0166|M.avium_104 PSLLAVAGVHHHLVRDRTRTHVGLVVESGDAREVHHMAALVGFGAAAINP
MLBr_00061|M.leprae_Br4923 PSLLSVAAVHHHLVRDRTRTHVGLVVESGDAREVHHMAALIGFGAAAVNP
MAB_0091|M.abscessus_ATCC_1997 PSLLAVAAVHHHLVRERSRTKVGLVVEAGDAREVHHVAALVGFGAAAVNP
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 RRGGDVKALYGRCAHRGVLLADGHIDGDTVVCDVHGWRYNVETGISPVNP
MMAR_1226|M.marinum_M ----------MKP--RSVAAVLGGGMAGVAGWDLWQRRH-----------
MUL_2666|M.ulcerans_Agy99 ----------MKP--RSVAAVLGGGMAGVAGWDLWQRRH-----------
TH_2993|M.thermoresistible__bu ----------MSSLFRTAAATAASALAAVAVHDVFQRRR-----------
Mb3889c|M.bovis_AF2122/97 YLVFESIEDMLDRGVIEGIDRTAALNNYIKAAGKGVLKVMSKMGISTLAS
Rv3859c|M.tuberculosis_H37Rv YLVFESIEDMLDRGVIEGIDRTAALNNYIKAAGKGVLKVMSKMGISTLAS
MAV_0166|M.avium_104 YMVFESIEDMLDRGVIEGIDRNTALNNYVKAAGKGVLKVMSKMGISTLAS
MLBr_00061|M.leprae_Br4923 YLVFESIEEMLDRGVIDGIDRKTALNNYIKATGQGVLKIMSKMGISTLAS
MAB_0091|M.abscessus_ATCC_1997 YMAFESIEDLIDRGVITGVDRDKAIRNYIKAAGKGVLKVMSKMGISTLAS
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 AVALATFPVQIRDGAVY-------------------------VDVSAISE
MMAR_1226|M.marinum_M -AILRNFPIIGHLRFLL-------------------------EAVG----
MUL_2666|M.ulcerans_Agy99 -AILRNFPIIGHLRFLL-------------------------EAVG----
TH_2993|M.thermoresistible__bu -AILRNFPVIGHARYLL-------------------------ESIG----
Mb3889c|M.bovis_AF2122/97 YTGAQLFQAVGISEQVLDEYFTGLTCPTGGITLDDIAADVAARHRLAYLD
Rv3859c|M.tuberculosis_H37Rv YTGAQLFQAVGISEQVLDEYFTGLTCPTGGITLDDIAADVAARHRLAYLD
MAV_0166|M.avium_104 YTGAQLFQAVGISEDVLDEYFTGLSCPIGGITLDDIAADVAARHALAYLD
MLBr_00061|M.leprae_Br4923 YVGAQLFQAVGISEDVLDEYFSGLSCPTGGITLDDIAAEVAVRHRVAYLD
MAB_0091|M.abscessus_ATCC_1997 YTGAQLFQAIGLSQELLDEYFTGLACPTGGIGLDEIAADVASRHNLAFLD
Mflv_1297|M.gilvum_PYR-GCK ------MTYT-----------------------DDDRARLGLRESATFDR
Mvan_5512|M.vanbaalenii_PYR-1 ------MSYS-----------------------SDDRARLGLRESATFDR
MSMEG_5594|M.smegmatis_MC2_155 FANANPQPYG-----------------------DDGYQGRWATPANTAEE
MMAR_1226|M.marinum_M -PELRQYIVT-----------------------DNNEERPFSRDQRRWVY
MUL_2666|M.ulcerans_Agy99 -PELRQYIVT-----------------------DNNEERPFSRDQRRWVY
TH_2993|M.thermoresistible__bu -PELRQYIVA-----------------------GDDEERPFTRDQRRWVY
.:
Mb3889c|M.bovis_AF2122/97 RPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHSTRTGQYKIFKEY
Rv3859c|M.tuberculosis_H37Rv RPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHSTRTGQYKIFKEY
MAV_0166|M.avium_104 RPNERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHATRTGQYKIFKDY
MLBr_00061|M.leprae_Br4923 RPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHATRSGQYKIFKEY
MAB_0091|M.abscessus_ATCC_1997 RPEEWAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHSTRTGQYSVFKEY
Mflv_1297|M.gilvum_PYR-GCK TTIAAIQRAADTG----IYDIRGWG-------AKRPLPHFDDLLFLGASM
Mvan_5512|M.vanbaalenii_PYR-1 ATIAAIQRAADTG----IYDIRGWG-------AKRPLPHFDDLLFLGASM
MSMEG_5594|M.smegmatis_MC2_155 PFNTDIHELATHG----LSRVGKHGPSAAMGVSRTELPSWDSIQLVTAQL
MMAR_1226|M.marinum_M TSSKLTNRYFGFG----TDNDLERA-------HNYPIIKHAAFPVSAPDG
MUL_2666|M.ulcerans_Agy99 TSSKLTNRYFGFG----TDNDLERA-------HNYPIIKHAAFPVSAPDG
TH_2993|M.thermoresistible__bu ASAKQENNYFSFG----TDNDIEYT-------SGYPVIRHRTFGRSIPAS
:. *
Mb3889c|M.bovis_AF2122/97 TRLVDDQSERMASLRGLLKFRTGVRPPVPLDEVEPASEIVKRFSTGAMSY
Rv3859c|M.tuberculosis_H37Rv TRLVDDQSERMASLRGLLKFRTGVRPPVPLDEVEPASEIVKRFSTGAMSY
MAV_0166|M.avium_104 TRLVDDQSERMASLRGLLKFRAGVRPPVPLEEVEPASEIVKRFSTGAMSY
MLBr_00061|M.leprae_Br4923 TRLVDDQSERMASLRGLLKFRSGVRTPVPLDEVEPASEIVKRFSTGAMSY
MAB_0091|M.abscessus_ATCC_1997 TQLVDDQSERMASLRGLLKFKTGVRPPVPLDEVEPASEIVKRFSTGAMSF
Mflv_1297|M.gilvum_PYR-GCK SRYPLEGYRERCATDVVLGDRHAKHPLHLEIPVT----------IAGMSF
Mvan_5512|M.vanbaalenii_PYR-1 SRYPLEGYRERCATDVVLGDRFAKHPLHLDIPVT----------IAGMSF
MSMEG_5594|M.smegmatis_MC2_155 ARLPLLDQ-EPVSTETVIGP-GAKRPLVLDIPLF----------VSDMSF
MMAR_1226|M.marinum_M EPAHPDPAVALPAAKVLGGARGRAKAFRPSSLVN----------ISGMSY
MUL_2666|M.ulcerans_Agy99 EPAHPDPAVALPAAKVLGGARGRAKAFRPSSLVN----------ISGMSY
TH_2993|M.thermoresistible__bu APR-AALDVELPAAKVIGAARNRAQAFRPQSVVN----------IGAMSF
: : :. : . **:
Mb3889c|M.bovis_AF2122/97 GSISAEAHETLAIAMNRLGARSNCGEGGEDVKRFDRDPNGDWRRSAIKQV
Rv3859c|M.tuberculosis_H37Rv GSISAEAHETLAIAMNRLGARSNCGEGGEDVKRFDRDPNGDWRRSAIKQV
MAV_0166|M.avium_104 GSISAEAHETLAIAMNRLGGRSNSGEGGEDVKRFDRDPDGSWRRSAIKQV
MLBr_00061|M.leprae_Br4923 GSISAEAHETLAIAMNRLGGRSNSGEGGEDVNRFEPDPNGDWRRSAIKQV
MAB_0091|M.abscessus_ATCC_1997 GSISAEAHETLAIAMNRLGGRSNSGEGGEDPRRFTPDENGDWRRSAIKQV
Mflv_1297|M.gilvum_PYR-GCK GALSGPAKEALGRGASEVGTSTTTGDGGMTPEERGQSKY------LVYQY
Mvan_5512|M.vanbaalenii_PYR-1 GALSGPAKEALGRGASEVGTSTTTGDGGMTPEERGQSKY------LVYQY
MSMEG_5594|M.smegmatis_MC2_155 GALSEEAKTALAAGAELAGTGICSGEGGMLPEEQQENSR------YFYEL
MMAR_1226|M.marinum_M GALGGAAISALNQGAAIAGALHTTGEGAVSPYHLNGGD-------LVWQI
MUL_2666|M.ulcerans_Agy99 GALGGAAISALNQGAGIAGALHTTGEGAVSPYHLNGGD-------LVWQI
TH_2993|M.thermoresistible__bu GSLSGKAIEALNRGAALAGCLHNTGEGGISRYHRHGGE-------LIFQI
*::. * :* . * *:*. . . . :
Mb3889c|M.bovis_AF2122/97 ASARFGVTSHY--------------LTNCTDLQIKMAQGAKPGEGGQLPG
Rv3859c|M.tuberculosis_H37Rv ASARFGVTSHY--------------LTNCTDLQIKMAQGAKPGEGGQLPG
MAV_0166|M.avium_104 ASGRFGVTSHY--------------LTNCTDIQIKMAQGAKPGEGGQLPG
MLBr_00061|M.leprae_Br4923 ASARFGVTSHY--------------LTNCTDIQIKMAQGAKPGEGGQLPG
MAB_0091|M.abscessus_ATCC_1997 ASGRFGVTSHY--------------LSNCTDIQIKMAQGAKPGEGGQLPA
Mflv_1297|M.gilvum_PYR-GCK LPSRYGMNPDD--------------LRKADAIEVVLGQGAKPGGGGMLLG
Mvan_5512|M.vanbaalenii_PYR-1 LPSRYGMNPED--------------LRKADAIEIVLGQGAKPGGGGMLLG
MSMEG_5594|M.smegmatis_MC2_155 ASGRFGWSFEH--------------LHKVQAFHFKGGQGAKTGTGGHLPG
MMAR_1226|M.marinum_M GTGYFGCRNDDGTFSLSRLIDRVAATPSIRAIEIKLSQGAKPGLGGMLPG
MUL_2666|M.ulcerans_Agy99 GTGYFGCRNDDGTFSLSRLIDRVAATTSIRAIEIKLSQGAKPGLGGMLPG
TH_2993|M.thermoresistible__bu GTAYFGCRDAEGRFDLARLKDLVAGAP-VRALEIKLSQGAKPTLGGVLPA
.. :* :.. .****. ** * .
Mb3889c|M.bovis_AF2122/97 HKVYPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARV
Rv3859c|M.tuberculosis_H37Rv HKVYPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARV
MAV_0166|M.avium_104 HKVYPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPAARV
MLBr_00061|M.leprae_Br4923 RKVYPWIAQVRNSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARV
MAB_0091|M.abscessus_ATCC_1997 HKVYPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNSNPQARI
Mflv_1297|M.gilvum_PYR-GCK QKISERVAGMRTLPEGIDQRSACRHPDWTGPDDLTIKINELREITDWEKP
Mvan_5512|M.vanbaalenii_PYR-1 QKISERVAGMRTLPEGIDQRSACRHPDWTGPDDLTIKINELREITDWEKP
MSMEG_5594|M.smegmatis_MC2_155 SKVVGKIADVRGLPPGTSAISPARFPDWTSLAEYRDFAAQVRDISG-GIP
MMAR_1226|M.marinum_M AKVTADIAAIRGIPVGVDCKSPAGHSAFADIDGMLELVETIADATGLPVG
MUL_2666|M.ulcerans_Agy99 AKVTADIAAIRGIPVGVDCKSPAGHSAFADIDGMLELVETIADATGLPVG
TH_2993|M.thermoresistible__bu AKVSAEIAATRGIPEGRDCVSPSRHAEFTDADSMLDWVEMLAAETGLPVG
*: :* * . * . *. . . : .
Mb3889c|M.bovis_AF2122/97 HVKLVSENGVGTVAAGVSK---AHADVVLISGHDGGTGATPLTSMKHAGA
Rv3859c|M.tuberculosis_H37Rv HVKLVSENGVGTVAAGVSK---AHADVVLISGHDGGTGATPLTSMKHAGA
MAV_0166|M.avium_104 HVKLVSENGVGTVAAGVSK---AHADVVLISGHDGGTGATPLTSMKHAGA
MLBr_00061|M.leprae_Br4923 HVKLVSENGVGTVAAGVSK---AHADVVLVSGHDGGTGATPLTSMKHSGA
MAB_0091|M.abscessus_ATCC_1997 HVKLVSENGVGTVATGVSK---AHADVVLISGHDGGTGATPLTSMKHAGA
Mflv_1297|M.gilvum_PYR-GCK IYVKVGATRTYYDVKLAVH---AGADVVVVDGMQGGTAATQEVFIEHVGI
Mvan_5512|M.vanbaalenii_PYR-1 IYVKVGASRTYYDVKLAVH---AGADVVVVDGMQGGTAATQEVFIEHVGI
MSMEG_5594|M.smegmatis_MC2_155 VGYKLSAQHIERDLDAALE---IGVDYVILDGRGGGTGSAPTIFPRHISV
MMAR_1226|M.marinum_M IKSAVGEGLFWPQLAARMARTGRGVDFVTVDGGEGGTGAAPLVFSDHVAL
MUL_2666|M.ulcerans_Agy99 IKSAVGEGLFWPQLAARMARTGRGVDFVTVDGGEGGTGAAPLVFSDHVAL
TH_2993|M.thermoresistible__bu IKSAVGDLDFWEQLTDLMRDTGRGVDFVSIDGGEGGTGAAPLIFTDTVSL
:. .* * :.* ***.:: .
Mb3889c|M.bovis_AF2122/97 PWELGLAETQQTLLLNGLRDR----------IVVQVDGQLKTGRDVMIAT
Rv3859c|M.tuberculosis_H37Rv PWELGLAETQQTLLLNGLRDR----------IVVQVDGQLKTGRDVMIAT
MAV_0166|M.avium_104 PWELGLAETQQTLLLNGLRDR----------IVVQVDGQLKTGRDVMIAA
MLBr_00061|M.leprae_Br4923 PWELGLAETQQTLLLNGLRDR----------IVVQVDGQLKTGRDVMIAA
MAB_0091|M.abscessus_ATCC_1997 PWELGLAETQQTLLLNGLRDR----------IVVQVDGQLKTGRDVMIAM
Mflv_1297|M.gilvum_PYR-GCK PTLAAIPQAVQALQELGVHRTGASGATGVDGVQLIVSGGIRNGADVAKAL
Mvan_5512|M.vanbaalenii_PYR-1 PTLAAIPQAVQALQELGVHRK----------VQLIVSGGIRNGADVAKAL
MSMEG_5594|M.smegmatis_MC2_155 PTIPALARARRHLDRSESRIT------------LAVTGGIRTPADMVKAL
MMAR_1226|M.marinum_M PFKWAFPRVFRAFAEEDLHHD----------VVFIGSAKLGIPENALLAL
MUL_2666|M.ulcerans_Agy99 PFKWAFPRVFRAFAEEDLHHD----------VVFIGSAKLGIPENALLAL
TH_2993|M.thermoresistible__bu PFQLGFAEVYRIFAERGLHEQ----------VTFIGSGKLGLPDNAVVAF
* .:... : : : . . : : *
Mb3889c|M.bovis_AF2122/97 LLGAEEFGFATAPLVVAGCIM----------------MRVCHLDTCPVGV
Rv3859c|M.tuberculosis_H37Rv LLGAEEFGFATAPLVVAGCIM----------------MRVCHLDTCPVGV
MAV_0166|M.avium_104 LLGAEEFGFATAPLVVSGCIM----------------MRVCHLDTCPVGV
MLBr_00061|M.leprae_Br4923 LLGAEEFGFATAPLVVAGCIM----------------MRVCHLDTCPVGV
MAB_0091|M.abscessus_ATCC_1997 LLGGEEFGFATAPLVVSGCIM----------------MRVCHLDTCPVGV
Mflv_1297|M.gilvum_PYR-GCK ALGADAVAIGTAALIALGDNHPRYASEYEKLGSAAGFYDDYQDGRDPAGI
Mvan_5512|M.vanbaalenii_PYR-1 ALGADAVAIGTAALIALGDNHPRYAAEYEKLGSAAGFFDDFQDGRDPAGI
MSMEG_5594|M.smegmatis_MC2_155 ALGADAIGVANSAIQAIGCVG----------------MRACHTNACPAGI
MMAR_1226|M.marinum_M TMGVDMINVGRTAMFAIGCIQ----------------AQRCHTGRCPSGV
MUL_2666|M.ulcerans_Agy99 AMGADMINVGRTAMFAIGCIQ----------------AQRCHTGRCPSGV
TH_2993|M.thermoresistible__bu ALGCDMVYAARESMLALGCIQ----------------AKKCHTDTCPTGV
:* : . . .: . * : . * *:
Mb3889c|M.bovis_AF2122/97 ATQNPLLRERFTGKPEFVENFFMFIAEEVREYLAQLGFRTVNEAVGQAGA
Rv3859c|M.tuberculosis_H37Rv ATQNPLLRERFTGKPEFVENFFMFIAEEVREYLAQLGFRTVNEAVGQAGA
MAV_0166|M.avium_104 ATQNPVLRERFTGKPEFVENFFMFIAEEVREYMAQLGFRTLNEAVGQVKS
MLBr_00061|M.leprae_Br4923 ATQNPLLRKRFNGKPEFVENFFMFIAEEVREYMAQLGFRTFNEAVGQVGA
MAB_0091|M.abscessus_ATCC_1997 ATQNPVLRQRFNGKPEFVENFFLFIAEEVRELMAELGFRTVNEAVGQVGA
Mflv_1297|M.gilvum_PYR-GCK STQDPELAARFDPIA---------GGHRLANYLRVLTMEAQTIARACGKS
Mvan_5512|M.vanbaalenii_PYR-1 STQDPELAARFDPIA---------GGHRLANYLRVLTMEAQTIARACGKS
MSMEG_5594|M.smegmatis_MC2_155 ATQDPHLRARLPVRQ---------AAERLNRYLRSAVDLMVVLARACGHH
MMAR_1226|M.marinum_M ATQSAWLQHGLDPAL---------KAVRCANYLATLRFELLSLARACGYV
MUL_2666|M.ulcerans_Agy99 ATQSAWLQHGLDPAL---------KAVRCANYLATLRFELLSLARACGYV
TH_2993|M.thermoresistible__bu ATQNAWLTRGLVPDD---------KAPRVANYIRTLRRDLVKVAEACGVE
:**.. * : . . . : * .
Mb3889c|M.bovis_AF2122/97 LDTTLARAHWKAHKLDLAPVLHEPESAFMNQDLYCSSRQDHGLDKALDQQ
Rv3859c|M.tuberculosis_H37Rv LDTTLARAHWKAHKLDLAPVLHEPESAFMNQDLYCSSRQDHGLDKALDQQ
MAV_0166|M.avium_104 LDTTLARAHWKAHRLDLGPVLHEPESAFMNQDLYCSSRQDHGLDKALDQQ
MLBr_00061|M.leprae_Br4923 LDTTPVREHWKAHSIDLTPVLHEPESAFMNQDLYCSSRQDHGLDKVLDQQ
MAB_0091|M.abscessus_ATCC_1997 LDIERAVAHWKASKIDLTPVLTEPESAFMNQDLYCSGSQDHGLEKALDQQ
Mflv_1297|M.gilvum_PYR-GCK HVCHLEPDDLVAVSIEAAAMARVPLAGTDWIPGQRT--------------
Mvan_5512|M.vanbaalenii_PYR-1 HVCHLEPDDLVAVSIEAAAMARIPLAGTDWIPGRNGGAW-----------
MSMEG_5594|M.smegmatis_MC2_155 RLAEFTLDDLTTFDRDFAYLSGVPYGGVTPL-------------------
MMAR_1226|M.marinum_M HPALVPLQAIELLDVDLQTVQVDDLFGYQPGWGIPSPADVAAITALMTK-
MUL_2666|M.ulcerans_Agy99 HPALVPLQAIELLDVDLQTVQVDDLFGYQPGWGIPSPADVAAITALMTK-
TH_2993|M.thermoresistible__bu HPGLISGDLIDILDGHTSARSLYEVYGYQPGMGLPSAEDRAEILRLMADR
. .
Mb3889c|M.bovis_AF2122/97 LIVMSREALDSGKPVRFSTTIGNVNRTVGTMLGHELTKAYGGQGLPDGTI
Rv3859c|M.tuberculosis_H37Rv LIVMSREALDSGKPVRFSTTIGNVNRTVGTMLGHELTKAYGGQGLPDGTI
MAV_0166|M.avium_104 LIVMSREALDSGKPVRFSTTISNVNRTVGTMLGHEVTKAYGGQGLPDGTI
MLBr_00061|M.leprae_Br4923 LIAVSRDALDFGKPVRFSTTIGNVNRTVGTMLGHELTKAYGAQGLPDGTI
MAB_0091|M.abscessus_ATCC_1997 LIVMSREALDHGTPVKFETLITNVNRTVGTMLGHEVTKAYGGEGLPDDTI
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M -----ASPPR----------------------------------------
MUL_2666|M.ulcerans_Agy99 -----ASPPR----------------------------------------
TH_2993|M.thermoresistible__bu ATRGGSAPPSHSAPAR----------------------------------
Mb3889c|M.bovis_AF2122/97 DITFDGSAGNSFGAFVPKGITLRVYGDANDYVGKGLSGGRIVVRPSDDAP
Rv3859c|M.tuberculosis_H37Rv DITFDGSAGNSFGAFVPKGITLRVYGDANDYVGKGLSGGRIVVRPSDDAP
MAV_0166|M.avium_104 DITFDGSAGNSFGAFVPRGITLRVYGDANDYVGKGLSGGRIVVRPSDNAP
MLBr_00061|M.leprae_Br4923 DITFEGSAGNSFGAFVPKGITLRVYGDANDYVGKGLSGGRIVVRPSDSVP
MAB_0091|M.abscessus_ATCC_1997 DITFTGSAGNSFGAFVPRGITLRLFGDANDYVGKGLSGGHIVVRPSREAP
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 QDYVAEDNIIGGNVILFGATSGEVYLRGVVGERFAVRNSGAHAVVEGVGD
Rv3859c|M.tuberculosis_H37Rv QDYVAEDNIIGGNVILFGATSGEVYLRGVVGERFAVRNSGAHAVVEGVGD
MAV_0166|M.avium_104 ADYVAEDNIIGGNVILFGATSGEAYLRGVVGERFAVRNSGAHAVVEGVGD
MLBr_00061|M.leprae_Br4923 LNYVAEDNIIGGNVILFGATSGEVYLRGVVGERFAVRNSGAHAVVEGVGD
MAB_0091|M.abscessus_ATCC_1997 EGFVAEKNIIGGNVILFGATSGEAFLNGVVGERFAVRNSGAAAVVEGVGD
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 HGCEYMTGGRVVILGRTGRNFAAGMSGGVAYVYDPDGELPANLNSEMVEL
Rv3859c|M.tuberculosis_H37Rv HGCEYMTGGRVVILGRTGRNFAAGMSGGVAYVYDPDGELPANLNSEMVEL
MAV_0166|M.avium_104 HGCEYMTGGKVVVLGRTGRNFAAGMSGGVAYIYDPPGEFPQHLNAEMVEL
MLBr_00061|M.leprae_Br4923 HGCEYMTGGKVVILGRTGRNFAAGMSGGEAYVYDSDGELPANLNFEMVEL
MAB_0091|M.abscessus_ATCC_1997 HGCEYMTGGTVVVLGPTGRNFAAGMSGGVAYVYDPDKRLMDNLNDEMVDL
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 ETLDEDDADWLHGTIQVHVDATDSAVGQRILSDWSGQQRHFVKVMPRDYK
Rv3859c|M.tuberculosis_H37Rv ETLDEDDADWLHGTIQVHVDATDSAVGQRILSDWSGQQRHFVKVMPRDYK
MAV_0166|M.avium_104 ESLDDDDIEWLHGMIQAHVDATDSAVGQRILGDWAQQQRHFVKVMPRDYK
MLBr_00061|M.leprae_Br4923 EPLDFDDAAWLYATIQAHVDATDSAVGQRILAGWSEQQRYFVKVMPKDYK
MAB_0091|M.abscessus_ATCC_1997 DALDPDDQQVLRSLIEKHVAATDSAVGQRILADWSGHSDSFVKVMPRDYR
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 RVLQAIALAERDGVDVDKAIMAAAHG
Rv3859c|M.tuberculosis_H37Rv RVLQAIALAERDGVDVDKAIMAAAHG
MAV_0166|M.avium_104 RVLQAIAEAERDGGDVDKAIMAAAHG
MLBr_00061|M.leprae_Br4923 RVLQAIALAERNGVDVNKVIMEPAHG
MAB_0091|M.abscessus_ATCC_1997 RVLEAIADAELTGGDVNEAIMAAARG
Mflv_1297|M.gilvum_PYR-GCK --------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------
MSMEG_5594|M.smegmatis_MC2_155 --------------------------
MMAR_1226|M.marinum_M --------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------
TH_2993|M.thermoresistible__bu --------------------------