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M. marinum M MMAR_1226 (gltB_1)

annotation: glutamate synthase, GltB_1
coordinates: 1490297 - 1491841
length: 514

MKPRSVAAVLGGGMAGVAGWDLWQRRHAILRNFPIIGHLRFLLEAVGPELRQYIVTDNNEERPFSRDQRR
WVYTSSKLTNRYFGFGTDNDLERAHNYPIIKHAAFPVSAPDGEPAHPDPAVALPAAKVLGGARGRAKAFR
PSSLVNISGMSYGALGGAAISALNQGAAIAGALHTTGEGAVSPYHLNGGDLVWQIGTGYFGCRNDDGTFS
LSRLIDRVAATPSIRAIEIKLSQGAKPGLGGMLPGAKVTADIAAIRGIPVGVDCKSPAGHSAFADIDGML
ELVETIADATGLPVGIKSAVGEGLFWPQLAARMARTGRGVDFVTVDGGEGGTGAAPLVFSDHVALPFKWA
FPRVFRAFAEEDLHHDVVFIGSAKLGIPENALLALTMGVDMINVGRTAMFAIGCIQAQRCHTGRCPSGVA
TQSAWLQHGLDPALKAVRCANYLATLRFELLSLARACGYVHPALVPLQAIELLDVDLQTVQVDDLFGYQP
GWGIPSPADVAAITALMTKASPPR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_1226gltB_1-100% (514)glutamate synthase, GltB_1
M. marinum MMMAR_5413gltB2e-2030.20% (202) ferredoxin-dependent glutamate synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3889cgltB2e-2127.27% (286) putative ferredoxin-dependent glutamate synthase
M. gilvum PYR-GCKMflv_0988-1e-16757.84% (510) ferredoxin-dependent glutamate synthase
M. tuberculosis H37RvRv3859cgltB3e-2127.27% (286) ferredoxin-dependent glutamate synthase
M. leprae Br4923MLBr_00061gltB6e-2227.97% (286) putative ferredoxin-dependent glutamate synthase
M. abscessus ATCC 19977MAB_2486c-2e-2729.58% (311) glutamate synthase, large subunit
M. avium 104MAV_0166-2e-2127.62% (286) ferredoxin-dependent glutamate synthase 1
M. smegmatis MC2 155MSMEG_6263-1e-3732.74% (336) glutamate synthase family protein
M. thermoresistible (build 8)TH_2993-1e-17158.73% (504) PUTATIVE ferredoxin-dependent glutamate synthase
M. ulcerans Agy99MUL_2666gltB_10.099.22% (514) glutamate synthase, GltB_1
M. vanbaalenii PYR-1Mvan_5847-1e-16859.69% (511) ferredoxin-dependent glutamate synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3889c|M.bovis_AF2122/97           --MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLNLEHR
Rv3859c|M.tuberculosis_H37Rv        --MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLNLEHR
MAV_0166|M.avium_104                MHMTPKRAGLYNPAFEHDACGVAMVVDMHGRRSRDIVDKAITALLNLEHR
MLBr_00061|M.leprae_Br4923          --MTAKRVGLYNPAFEHDSCGVAMVVDMYGRRTRDIVDKAITALLNLEHR
MAB_2486c|M.abscessus_ATCC_199      --------------------------------------------------
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           GAQGAEPRSGDGAGILIQVPDEFLREAVDFELPAPGSYATGIAFLPQSSK
Rv3859c|M.tuberculosis_H37Rv        GAQGAEPRSGDGAGILIQVPDEFLREAVDFELPAPGSYATGIAFLPQSSK
MAV_0166|M.avium_104                GAQGAEPRSGDGAGILIQVPDAFLREVVDFELPPEGSYATGIAFLPQSSK
MLBr_00061|M.leprae_Br4923          GAQGAEPRSGDGAGILIQVPDAFLRAVVDFELPAASSYATGIAFLPQSSK
MAB_2486c|M.abscessus_ATCC_199      ---MSSEGVGDGAGVNLDLSLRFFSELTGVSDLRHGQFGVGNFFLPNDPA
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           DAAAACAAVQKIAEAEGLQVLGWRSVPTDDSSLGALSRDAMPTFRQVFLA
Rv3859c|M.tuberculosis_H37Rv        DAAAACAAVQKIAEAEGLQVLGWRSVPTDDSSLGALSRDAMPTFRQVFLA
MAV_0166|M.avium_104                DAATACAAVEKIAEAEGLTVLGWRNVPTDDSSLGALSRDAMPTFRQVFMA
MLBr_00061|M.leprae_Br4923          DAAAACAAVEKIAVAEGLHVLGWRNVPTDASSLGALSRDAMPTFRQVFMA
MAB_2486c|M.abscessus_ATCC_199      SHAEAEQVIEQALRAQGFTILLSRDVPVNNDAIRPAAIKYQLPIRQWVFR
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           GASGMALERRCYVVRKRAEHELGTKGPGQDGPGRETVYFPSLSGQTLVYK
Rv3859c|M.tuberculosis_H37Rv        GASGMALERRCYVVRKRAEHELGTKGPGQDGPGRETVYFPSLSGQTLVYK
MAV_0166|M.avium_104                GASGMTLERRAYLVRKRAEHELGTKGPGQDGPGRETVYFPSLSGQTFVYK
MLBr_00061|M.leprae_Br4923          GATGLTLERRAYVIRKRAEHELGTKGPGQDGPGRETIYFPSLSSQTFVYK
MAB_2486c|M.abscessus_ATCC_199      SDS----------ERKTHEALMAIESVAYTRPELLGLYPLSLSTRTQVLK
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           GMLTTPQLKAFYLDLQDERLTSALGIVHSRFSTNTFPSWPLAHPFRRIAH
Rv3859c|M.tuberculosis_H37Rv        GMLTTPQLKAFYLDLQDERLTSALGIVHSRFSTNTFPSWPLAHPFRRIAH
MAV_0166|M.avium_104                GMLTTPQLKAFYLDLQDDRLTSALGIVHSRFSTNTFPSWPLAHPFRRIAH
MLBr_00061|M.leprae_Br4923          GMLTTPQLKAFYRDLQDERLTSALGIVHSRFSTNTFPSWPLAHPFRRIAH
MAB_2486c|M.abscessus_ATCC_199      GRLNSNEVVPYFSDLSDPRMEVHSMFFHTRFSTNTAPNATMAQPFRLMAH
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           NGEINTVTGNENWMRAREALIKTDIFGSAADVEKLFPICTPGASDTARFD
Rv3859c|M.tuberculosis_H37Rv        NGEINTVTGNENWMRAREALIKTDIFGSAADVEKLFPICTPGASDTARFD
MAV_0166|M.avium_104                NGEINTVTGNENWMRAREALIKTDVFGTEADVEKLFPICTPGASDTARFD
MLBr_00061|M.leprae_Br4923          NGEINTVTGNENWMRAREALMKTDIFGSKADMEKLFPICTPGASDTARFD
MAB_2486c|M.abscessus_ATCC_199      NGELNTDKKNRLSENAIARARNRAIIR------------PVGQSDSCRLD
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           EVLELLHLGG-RSLAHAVLMMIPEAWERHESMDPARRAFYQYHASLMEPW
Rv3859c|M.tuberculosis_H37Rv        EVLELLHLGG-RSLAHAVLMMIPEAWERHESMDPARRAFYQYHASLMEPW
MAV_0166|M.avium_104                EVLELLHLGG-RSLAHAVLMMIPEAWERHESMDPARRAFYQYHASLMEPW
MLBr_00061|M.leprae_Br4923          EALELLHLGG-RSLVHAVLMMIPEAWERHESMDPARRAFYQYHASLMEPW
MAB_2486c|M.abscessus_ATCC_199      QTLQSRVLEDDLDLVTAVVAMMPPAWENDTTLSPRVTAMLEYFSLYEEKN
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           DGPASMTFTDGTVVGAVLDRNGLRPSRIWVTDDGLVVMASEAGVLDLHPS
Rv3859c|M.tuberculosis_H37Rv        DGPASMTFTDGTVVGAVLDRNGLRPSRIWVTDDGLVVMASEAGVLDLHPS
MAV_0166|M.avium_104                DGPASMTFTDGTVIGAVLDRNGLRPSRIWVTEDGLVVMASEAGVLDLDPA
MLBr_00061|M.leprae_Br4923          DGPASMTFTDGVVVGAVLDRNGLRPSRIWITDAGLVVMASEAGVLDLDPS
MAB_2486c|M.abscessus_ATCC_199      DGPAALIFGDGNIIGARLDRLGLRPLRTVETAEYLGVMS-EAGQIYFEPD
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           TVVRRMRLQPGRMFLVDTAQGRIVSDEEIKADLAAEHPYQEWLDNGLVPL
Rv3859c|M.tuberculosis_H37Rv        TVVRRMRLQPGRMFLVDTAQGRIVSDEEIKADLAAEHPYQEWLDNGLVPL
MAV_0166|M.avium_104                TVVRRMRLQPGRMFLVDTAQGRIVSDEEIKAELAAEHPYQEWLDRNLVPL
MLBr_00061|M.leprae_Br4923          IVVRRMRLQPGRMFLVDTAQGRIVSDEEIKAKLAAEHPYQEWLDKGLVPI
MAB_2486c|M.abscessus_ATCC_199      SVLERGRIEAGGMRYYDHSEGRSYNTVEALEMLAARHDYPAMLAQARVNI
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           DELPEGKDVRMPHHRIVM-------RQLAFGYTYEELNLLVAPMARLGAE
Rv3859c|M.tuberculosis_H37Rv        DELPEGKDVRMPHHRIVM-------RQLAFGYTYEELNLLVAPMARLGAE
MAV_0166|M.avium_104                DDLPQGDYKRMPHDRLVK-------RQQTFGYTYEELNLLVAPMVRTGAE
MLBr_00061|M.leprae_Br4923          DELPAGKYVRMPHHRLVM-------RQLAFGYTYEELNLLVAPMVRAGSE
MAB_2486c|M.abscessus_ATCC_199      ADLPHVPPAGQGSPARYDGDLDRHQRYVAYSLNQESFKFLMDPMLATGQE
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           PIGSMGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPPLDAIREEVVTSLQG
Rv3859c|M.tuberculosis_H37Rv        PIGSMGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPPLDAIREEVVTSLQG
MAV_0166|M.avium_104                PIGSMGTDTPVAVLSQRPRMLYDYFQQLFAQVTNPPLDAIREEVVTSLQG
MLBr_00061|M.leprae_Br4923          PIGSMGADTPIAVLSRRPRMLYDYFHQLFAQVTNPPLDAIREEVVTSLQG
MAB_2486c|M.abscessus_ATCC_199      KISAMGYGAAINALSNQEGGVAKYFSQRFAQVTNPPLDSIREADGMTLRV
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           TTGGERDLLNPDENSCHQIVLPQPILRNHELAKLVSLDPNDKVNGRPHGL
Rv3859c|M.tuberculosis_H37Rv        TTGGERDLLNPDQNSCHQIVLPQPILRNHELAKLVSLDPNDKVNGRPHGL
MAV_0166|M.avium_104                TTGGERDLLTPTELSCHQIVLSQPILRNRELAKLVNLNPDDEVNGRPHGM
MLBr_00061|M.leprae_Br4923          TTGGEYDLLSPDENSCHQIWLPQPILRNYELAKLVNLDPADEVNGRPHGM
MAB_2486c|M.abscessus_ATCC_199      ALGAKP---NSGAQPAPQIVVPSPILTHLDMLKIR---EQGRTPVRRFGM
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           RSKVIRCLYRVSEGGAGLAAALEEVRGAAAAAIADGARIIILSDRESDEE
Rv3859c|M.tuberculosis_H37Rv        RSKVIRCLYRVSEGGAGLAAALEEVRGAAAAAIADGARIIILSDRESDEE
MAV_0166|M.avium_104                RSKVIRCLYPVAEGGAGLAAALEDVRAQASAAIADGARVIILSDRESDEK
MLBr_00061|M.leprae_Br4923          RSTVVSCLYPVADAGAGLAAALTEVRAQASAAIVGGARVIILSDRNSDEQ
MAB_2486c|M.abscessus_ATCC_199      RYRVD--LTDAVSNAERIVRAIDDLCDAVEEFARETGGIAVISDRHVSSE
MMAR_1226|M.marinum_M               ------------------------MKPRSVAAVLGGGMAGVAGWDLWQRR
MUL_2666|M.ulcerans_Agy99           ------------------------MKPRSVAAVLGGGMAGVAGWDLWQRR
Mflv_0988|M.gilvum_PYR-GCK          -----------------------MKKRTLAALVPAAAAAGIAVQDLLQKE
Mvan_5847|M.vanbaalenii_PYR-1       -----------------------MKKRTLAALAPVAALAGVALQDLLQKE
TH_2993|M.thermoresistible__bu      ----------------------MSSLFRTAAATAASALAAVAVHDVFQRR
MSMEG_6263|M.smegmatis_MC2_155      -----------------------------------------MSYTTDDRA
                                                                                   .  

Mb3889c|M.bovis_AF2122/97           MAPIPSLLAVAGVHHHLVRERTRTQVGLVVESGDAREVHHMAALVGFGAA
Rv3859c|M.tuberculosis_H37Rv        MAPIPSLLAVAGVHHHLVRERTRTQVGLVVESGDAREVHHMAALVGFGAA
MAV_0166|M.avium_104                MAPIPSLLAVAGVHHHLVRDRTRTHVGLVVESGDAREVHHMAALVGFGAA
MLBr_00061|M.leprae_Br4923          MAPIPSLLSVAAVHHHLVRDRTRTHVGLVVESGDAREVHHMAALIGFGAA
MAB_2486c|M.abscessus_ATCC_199      RAAMPLIIVISAINQRLIEEGLRLRVSLIAESGQLCSSHHVAAVLGFGAS
MMAR_1226|M.marinum_M               HAILRNFPIIGHLRFLLEAVGPELRQYIVTDNNEERPFSRDQRRWVYTSS
MUL_2666|M.ulcerans_Agy99           HAILRNFPIIGHLRFLLEAVGPELRQYIVTDNNEERPFSRDQRRWVYTSS
Mflv_0988|M.gilvum_PYR-GCK          HALRRNFPLVARARYLLESIGPELRQYIITSNDAERPFSRDQRRWVYTSA
Mvan_5847|M.vanbaalenii_PYR-1       HALRHNFPVIARARYLLESIGPELRQYIITSNDSERPFSRDQRRWVYTSA
TH_2993|M.thermoresistible__bu      RAILRNFPVIGHARYLLESIGPELRQYIVAGDDEERPFTRDQRRWVYASA
MSMEG_6263|M.smegmatis_MC2_155      RLGLRESATFDRTTIAAIQRAADTGIYDIRGWGAKRPLPHFDDLLFLGAS
                                             .                  :   .      :        ::

Mb3889c|M.bovis_AF2122/97           AINPYLVFESIEDMLDRGVIEGIDRTAALNNYIKAAGKGVLKVMSKMGIS
Rv3859c|M.tuberculosis_H37Rv        AINPYLVFESIEDMLDRGVIEGIDRTAALNNYIKAAGKGVLKVMSKMGIS
MAV_0166|M.avium_104                AINPYMVFESIEDMLDRGVIEGIDRNTALNNYVKAAGKGVLKVMSKMGIS
MLBr_00061|M.leprae_Br4923          AVNPYLVFESIEEMLDRGVIDGIDRKTALNNYIKATGQGVLKIMSKMGIS
MAB_2486c|M.abscessus_ATCC_199      AVYPLAVQMRAEEKYGPDVDDAVN---AFKHFAKAAEKSLMKTMGRVGLC
MMAR_1226|M.marinum_M               KL--------TNRYFGFGTDNDLERAHNYPIIKHAAFPVSAPDGEPAHPD
MUL_2666|M.ulcerans_Agy99           KL--------TNRYFGFGTDNDLERAHNYPIIKHAAFPVSAPDGEPAHPD
Mflv_0988|M.gilvum_PYR-GCK          KK--------ENNYFAFGTDNDVEN-AAYPIIKQATFSDVVPAS-PIHLR
Mvan_5847|M.vanbaalenii_PYR-1       KK--------ENNYFSFGTDNDTEN-AAYPIIKQATFSDVVAAS-PIHGR
TH_2993|M.thermoresistible__bu      KQ--------ENNYFSFGTDNDIEYTSGYPVIRHRTFGRSIPASAPRAAL
MSMEG_6263|M.smegmatis_MC2_155      MS-------------------------------------------RYPLE
                                                                                      

Mb3889c|M.bovis_AF2122/97           TLASYTGAQLFQA--VGISEQVLDEYFTGLTCPTGGITLDDIAADVAARH
Rv3859c|M.tuberculosis_H37Rv        TLASYTGAQLFQA--VGISEQVLDEYFTGLTCPTGGITLDDIAADVAARH
MAV_0166|M.avium_104                TLASYTGAQLFQA--VGISEDVLDEYFTGLSCPIGGITLDDIAADVAARH
MLBr_00061|M.leprae_Br4923          TLASYVGAQLFQA--VGISEDVLDEYFSGLSCPTGGITLDDIAAEVAVRH
MAB_2486c|M.abscessus_ATCC_199      TVESYIGGEFFEPNYLDTSDPVLRKYFPNVVSPVAGVGFSTLAAAVADWH
MMAR_1226|M.marinum_M               PAVALPAAKVLGG-----ARGRAKAFRPSSLVNISGMSYGALGGAAISAL
MUL_2666|M.ulcerans_Agy99           PAVALPAAKVLGG-----ARGRAKAFRPSSLVNISGMSYGALGGAAISAL
Mflv_0988|M.gilvum_PYR-GCK          -DIEVPGAKVLGA-----PRGRRHAFRPASVVNVSAMSFGSLSPQAIEAI
Mvan_5847|M.vanbaalenii_PYR-1       -DIEVPGAKMLGG-----PRGRRHAFRPASVVNVSAMSFGSLSPQAIEAI
TH_2993|M.thermoresistible__bu      -DVELPAAKVIGA-----ARNRAQAFRPQSVVNIGAMSFGSLSGKAIEAL
MSMEG_6263|M.smegmatis_MC2_155      GYRERCGTDVVLG-----DRHAKHPLHLDIPVTIAGMSFGALSAGAKEAL
                                          . ...                       ..:  . :.  .    

Mb3889c|M.bovis_AF2122/97           R----------LAYLDRPDERAHRELEVGGEYQWR---------------
Rv3859c|M.tuberculosis_H37Rv        R----------LAYLDRPDERAHRELEVGGEYQWR---------------
MAV_0166|M.avium_104                A----------LAYLDRPNERAHRELEVGGEYQWR---------------
MLBr_00061|M.leprae_Br4923          R----------VAYLDRPDERAHRELEVGGEYQWR---------------
MAB_2486c|M.abscessus_ATCC_199      ARALAVTGEKDVPLLGLFKERAEGAGHSYGTTAVRGFVDMTEESISFGDE
MMAR_1226|M.marinum_M               N----------------QGAAIAGALHTTGEGAVS---------------
MUL_2666|M.ulcerans_Agy99           N----------------QGAGIAGALHTTGEGAVS---------------
Mflv_0988|M.gilvum_PYR-GCK          N----------------KGAKIADFLHNVGEGGLS---------------
Mvan_5847|M.vanbaalenii_PYR-1       N----------------KGAKIADFWHNTGEGGLS---------------
TH_2993|M.thermoresistible__bu      N----------------RGAALAGCLHNTGEGGIS---------------
MSMEG_6263|M.smegmatis_MC2_155      G----------------RGASEVGTSTTTGDGGMTP--------------
                                                                 *                    

Mb3889c|M.bovis_AF2122/97           -REGEYHLFNPETVFKLQHSTRTGQYKIFKEYTR----------------
Rv3859c|M.tuberculosis_H37Rv        -REGEYHLFNPETVFKLQHSTRTGQYKIFKEYTR----------------
MAV_0166|M.avium_104                -REGEYHLFNPETVFKLQHATRTGQYKIFKDYTR----------------
MLBr_00061|M.leprae_Br4923          -REGEYHLFNPETVFKLQHATRSGQYKIFKEYTR----------------
MAB_2486c|M.abscessus_ATCC_199      ARPENPDMADPTYLRLLPLHQLEGAFGLDDEAYRNNSFDELPTRAIDSFD
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           --------------------------------------------------
Rv3859c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_0166|M.avium_104                --------------------------------------------------
MLBr_00061|M.leprae_Br4923          --------------------------------------------------
MAB_2486c|M.abscessus_ATCC_199      ITPGYRNFVRAMNSERTRRPAALRDVLALPADVNFVRTADEFRREMGQFA
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           -----------------------LVDDQSERMASLRGLLKFRTG------
Rv3859c|M.tuberculosis_H37Rv        -----------------------LVDDQSERMASLRGLLKFRTG------
MAV_0166|M.avium_104                -----------------------LVDDQSERMASLRGLLKFRAG------
MLBr_00061|M.leprae_Br4923          -----------------------LVDDQSERMASLRGLLKFRSG------
MAB_2486c|M.abscessus_ATCC_199      RLGNNDFQVRGLSCQQTDDVFVLRLAHSPERLAALASSLRTRFGREITHH
MMAR_1226|M.marinum_M               ------------------------------PYHLNGGDLVWQIG------
MUL_2666|M.ulcerans_Agy99           ------------------------------PYHLNGGDLVWQIG------
Mflv_0988|M.gilvum_PYR-GCK          ------------------------------DHHRQGGELIYQIG------
Mvan_5847|M.vanbaalenii_PYR-1       ------------------------------DHHRQGGDLVYQIG------
TH_2993|M.thermoresistible__bu      ------------------------------RYHRHGGELIFQIG------
MSMEG_6263|M.smegmatis_MC2_155      ------------------------------EERGQSKHLVYQYLP-----
                                                                          *  :        

Mb3889c|M.bovis_AF2122/97           ------------------------VRPPVPLDEVEPASEIVKRFSTGAMS
Rv3859c|M.tuberculosis_H37Rv        ------------------------VRPPVPLDEVEPASEIVKRFSTGAMS
MAV_0166|M.avium_104                ------------------------VRPPVPLEEVEPASEIVKRFSTGAMS
MLBr_00061|M.leprae_Br4923          ------------------------VRTPVPLDEVEPASEIVKRFSTGAMS
MAB_2486c|M.abscessus_ATCC_199      EIVGDELRITATGQAADYLAQIRTAPESIPLSSVQPASEITPTLTSGAMS
MMAR_1226|M.marinum_M               -----------------------------------------------TGY
MUL_2666|M.ulcerans_Agy99           -----------------------------------------------TGY
Mflv_0988|M.gilvum_PYR-GCK          -----------------------------------------------TGY
Mvan_5847|M.vanbaalenii_PYR-1       -----------------------------------------------TGY
TH_2993|M.thermoresistible__bu      -----------------------------------------------TAY
MSMEG_6263|M.smegmatis_MC2_155      ------------------------------------------------SR
                                                                                      

Mb3889c|M.bovis_AF2122/97           YGSISAEAHETLAIAMNRLGARSNCGEGGEDVKRFDRDPNGDWRRSAIKQ
Rv3859c|M.tuberculosis_H37Rv        YGSISAEAHETLAIAMNRLGARSNCGEGGEDVKRFDRDPNGDWRRSAIKQ
MAV_0166|M.avium_104                YGSISAEAHETLAIAMNRLGGRSNSGEGGEDVKRFDRDPDGSWRRSAIKQ
MLBr_00061|M.leprae_Br4923          YGSISAEAHETLAIAMNRLGGRSNSGEGGEDVNRFEPDPNGDWRRSAIKQ
MAB_2486c|M.abscessus_ATCC_199      HGALVAPAHEAVAHGTNLVGGLSNCGEGGEHISRYG-----TIRGSRIKQ
MMAR_1226|M.marinum_M               FGCRNDDGTFSLSRLIDRVAATPS--------------------------
MUL_2666|M.ulcerans_Agy99           FGCRNDDGTFSLSRLIDRVAATTS--------------------------
Mflv_0988|M.gilvum_PYR-GCK          FGCRDEHGDFDLARLVDVVGAAP---------------------------
Mvan_5847|M.vanbaalenii_PYR-1       FGCRDEHGNFDLDRLVDVVGSGP---------------------------
TH_2993|M.thermoresistible__bu      FGCRDAEGRFDLARLKDLVAGAP---------------------------
MSMEG_6263|M.smegmatis_MC2_155      YGMNPDDLRK----------------------------------------
                                    .*                                                

Mb3889c|M.bovis_AF2122/97           VASARFGVTSHYLTN--CTDLQIKMAQGAKPGEGGQLPGHKVYPWVAEVR
Rv3859c|M.tuberculosis_H37Rv        VASARFGVTSHYLTN--CTDLQIKMAQGAKPGEGGQLPGHKVYPWVAEVR
MAV_0166|M.avium_104                VASGRFGVTSHYLTN--CTDIQIKMAQGAKPGEGGQLPGHKVYPWVAEVR
MLBr_00061|M.leprae_Br4923          VASARFGVTSHYLTN--CTDIQIKMAQGAKPGEGGQLPGRKVYPWIAQVR
MAB_2486c|M.abscessus_ATCC_199      FASGRFGVWAGYLADPMLQELEIKIGQGAKPGEGGQLPAPKVTVQIAAAR
MMAR_1226|M.marinum_M               -----------------IRAIEIKLSQGAKPGLGGMLPGAKVTADIAAIR
MUL_2666|M.ulcerans_Agy99           -----------------IRAIEIKLSQGAKPGLGGMLPGAKVTADIAAIR
Mflv_0988|M.gilvum_PYR-GCK          -----------------VRAIEIKLSQGAKPGLGGHLPGAKVNAEIARVR
Mvan_5847|M.vanbaalenii_PYR-1       -----------------VRAIEIKLSQGAKPGLGGHLPGAKVNAEIARIR
TH_2993|M.thermoresistible__bu      -----------------VRALEIKLSQGAKPTLGGVLPAAKVSAEIAATR
MSMEG_6263|M.smegmatis_MC2_155      -----------------ADAIEVVLGQGAKPGGGGMLLGQKISERVAGMR
                                                        ::: :.*****  ** * . *:   :*  *

Mb3889c|M.bovis_AF2122/97           HSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVKLVSE----
Rv3859c|M.tuberculosis_H37Rv        HSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVKLVSE----
MAV_0166|M.avium_104                HSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPAARVHVKLVSE----
MLBr_00061|M.leprae_Br4923          NSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVKLVSE----
MAB_2486c|M.abscessus_ATCC_199      GGTPGVELVSPPPHHDTYSIEDLAQLIHDCKAAR--VRVIVKLVSS----
MMAR_1226|M.marinum_M               GIPVGVDCKSPAGHSAFADIDGMLELVETIADATGLPVGIKSAVGEGLFW
MUL_2666|M.ulcerans_Agy99           GIPVGVDCKSPAGHSAFADIDGMLELVETIADATGLPVGIKSAVGEGLFW
Mflv_0988|M.gilvum_PYR-GCK          GVERGKDVVSPSRHTAFRNVDEMLDVVERIADATGLPVGIKSAVGEMGFW
Mvan_5847|M.vanbaalenii_PYR-1       GVEQGKDVASPSRHTAFRDVDEMLDLVERIADATGLPVGIKSAVGELDFW
TH_2993|M.thermoresistible__bu      GIPEGRDCVSPSRHAEFTDADSMLDWVEMLAAETGLPVGIKSAVGDLDFW
MSMEG_6263|M.smegmatis_MC2_155      TLPQGIDQRSACRHPDWTGPDDLTIKINELREITDWEKPIYVKVGATRTY
                                        *    *.  *    . : :   :.               *.     

Mb3889c|M.bovis_AF2122/97           NGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGLAETQ
Rv3859c|M.tuberculosis_H37Rv        NGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGLAETQ
MAV_0166|M.avium_104                NGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGLAETQ
MLBr_00061|M.leprae_Br4923          NGVGTVAAGVSKAHADVVLVSGHDGGTGATPLTSMKHSGAPWELGLAETQ
MAB_2486c|M.abscessus_ATCC_199      EGIGTIAVGVAKAGADVINVAGNTGGTGAAAVTSLKYAGRSAEIGVAEVH
MMAR_1226|M.marinum_M               PQLAARMAR-TGRGVDFVTVDGGEGGTGAAPLVFSDHVALPFKWAFPRVF
MUL_2666|M.ulcerans_Agy99           PQLAARMAR-TGRGVDFVTVDGGEGGTGAAPLVFSDHVALPFKWAFPRVF
Mflv_0988|M.gilvum_PYR-GCK          QELADRMAD-GQRGVDFIAIDGGEGGTGAAPLVFADHVSFPFRIGFTRVY
Mvan_5847|M.vanbaalenii_PYR-1       QTLADRMDDDGQRGVDFITIDGGEGGTGAAPLVFADHVSFPFRMGFARVY
TH_2993|M.thermoresistible__bu      EQLTDLMRD-TGRGVDFVSIDGGEGGTGAAPLIFTDTVSLPFQLGFAEVY
MSMEG_6263|M.smegmatis_MC2_155      YDVKLAVHS----GADVVVVDGMQGGTAATQEVFIEHVGIPTLAAIPQAV
                                      :           .*.: : *  ***.*:     .  . .   ..... 

Mb3889c|M.bovis_AF2122/97           QTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGAEEFGFATAPLVVAG--
Rv3859c|M.tuberculosis_H37Rv        QTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGAEEFGFATAPLVVAG--
MAV_0166|M.avium_104                QTLLLNGLRDRIVVQVDGQLKTGRDVMIAALLGAEEFGFATAPLVVSG--
MLBr_00061|M.leprae_Br4923          QTLLLNGLRDRIVVQVDGQLKTGRDVMIAALLGAEEFGFATAPLVVAG--
MAB_2486c|M.abscessus_ATCC_199      QALCANGIRQKVVLRCSGAHQTASDVVKSALLGADSFEFGTTALMMLK--
MMAR_1226|M.marinum_M               RAFAEEDLHHDVVFIGSAKLGIPENALLALTMGVDMINVGRTAMFAIG--
MUL_2666|M.ulcerans_Agy99           RAFAEEDLHHDVVFIGSAKLGIPENALLALAMGADMINVGRTAMFAIG--
Mflv_0988|M.gilvum_PYR-GCK          GLFAQAGLTDRVTWIGSGKLGLPANAIVAFALGVDLLNVAREAMLAIG--
Mvan_5847|M.vanbaalenii_PYR-1       GLFAERGLTDRVTWIGSAKLGLPANAIVAFALGVDLINVAREAMFAIG--
TH_2993|M.thermoresistible__bu      RIFAERGLHEQVTFIGSGKLGLPDNAVVAFALGCDMVYAARESMLALG--
MSMEG_6263|M.smegmatis_MC2_155      QALQELGVHRKVQLIVSGGIRNGADVAKALALGADAVAIGTAALIALGDN
                                      :   .:   :    ..      :.  :  :* : .  .  .:.     

Mb3889c|M.bovis_AF2122/97           --------------CIMMRVCHLDTCPVGVATQNPLLRERFTGKPEFVEN
Rv3859c|M.tuberculosis_H37Rv        --------------CIMMRVCHLDTCPVGVATQNPLLRERFTGKPEFVEN
MAV_0166|M.avium_104                --------------CIMMRVCHLDTCPVGVATQNPVLRERFTGKPEFVEN
MLBr_00061|M.leprae_Br4923          --------------CIMMRVCHLDTCPVGVATQNPLLRKRFNGKPEFVEN
MAB_2486c|M.abscessus_ATCC_199      --------------CVMAKNCNIK-CPAGLTTN----AEVFEGDPRALAQ
MMAR_1226|M.marinum_M               --------------CIQAQRCHTGRCPSGVATQSAWLQHGLDPALKAVR-
MUL_2666|M.ulcerans_Agy99           --------------CIQAQRCHTGRCPSGVATQSAWLQHGLDPALKAVR-
Mflv_0988|M.gilvum_PYR-GCK          --------------CIQAQKCHTDHCPTGVATQNPWLARGLDPEQKSHR-
Mvan_5847|M.vanbaalenii_PYR-1       --------------CIQAQKCHTDRCPTGVATQNAWLARGLDPEQKSHR-
TH_2993|M.thermoresistible__bu      --------------CIQAKKCHTDTCPTGVATQNAWLTRGLVPDDKAPR-
MSMEG_6263|M.smegmatis_MC2_155      HPRYAAEYEKIGSAAGFYDDFQDGRDPAGISTQDAELAARFDPIEGGRR-
                                                  .      :    * *::*:       :         

Mb3889c|M.bovis_AF2122/97           FFMFIAEEVREYLAQLGFRTVNEAVGQAGALDTTLARAHWKAHKLDLAPV
Rv3859c|M.tuberculosis_H37Rv        FFMFIAEEVREYLAQLGFRTVNEAVGQAGALDTTLARAHWKAHKLDLAPV
MAV_0166|M.avium_104                FFMFIAEEVREYMAQLGFRTLNEAVGQVKSLDTTLARAHWKAHRLDLGPV
MLBr_00061|M.leprae_Br4923          FFMFIAEEVREYMAQLGFRTFNEAVGQVGALDTTPVREHWKAHSIDLTPV
MAB_2486c|M.abscessus_ATCC_199      YLLNIAHEVREILAALGMRTLREARGRSDLLHLLDHPSSIGTLDLRRMLA
MMAR_1226|M.marinum_M               --------CANYLATLRFELLSLARACGYVHPALVPLQAIELLDVDLQTV
MUL_2666|M.ulcerans_Agy99           --------CANYLATLRFELLSLARACGYVHPALVPLQAIELLDVDLQTV
Mflv_0988|M.gilvum_PYR-GCK          --------LANYVQTLRRDLLKVSEAAGVRHPAMLGPTDVEILDGDRGHR
Mvan_5847|M.vanbaalenii_PYR-1       --------LANYVMTLRRDLLKVSEAAGVRHPAMLSPKHVEILDGDRGHR
TH_2993|M.thermoresistible__bu      --------VANYIRTLRRDLVKVAEACGVEHPGLISGDLIDILDGHTSAR
MSMEG_6263|M.smegmatis_MC2_155      --------LANYLRVLTMEAQTIARACGKAHVCHLEPEDLVAVTIEAAAM
                                              : :  *       : .                        

Mb3889c|M.bovis_AF2122/97           LHEPESAFMNQDLYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTT
Rv3859c|M.tuberculosis_H37Rv        LHEPESAFMNQDLYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTT
MAV_0166|M.avium_104                LHEPESAFMNQDLYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTT
MLBr_00061|M.leprae_Br4923          LHEPESAFMNQDLYCSSRQDHGLDKVLDQQLIAVSRDALDFGKPVRFSTT
MAB_2486c|M.abscessus_ATCC_199      VAEEFVVENPVYMEKDYSVDDAFAAQFDARGAVLKPVTLTNQNKSVGGQL
MMAR_1226|M.marinum_M               QVDDLFGYQPGWGIPSPADVAAITALMTKAS------------PPR----
MUL_2666|M.ulcerans_Agy99           QVDDLFGYQPGWGIPSPADVAAITALMTKAS------------PPR----
Mflv_0988|M.gilvum_PYR-GCK          TLAAVYGYQPGWGVPGPEIVAEIDTYMSRYDDRPGTDTVVEHEPLKLATD
Mvan_5847|M.vanbaalenii_PYR-1       PLADVYGYQEWWGTPGPEIVDEIDAYMRRYDDLPGTHEVVEHEPLKVAAE
TH_2993|M.thermoresistible__bu      SLYEVYGYQPGMGLPSAEDRAEILRLMADRATRGGSAPPSHSAPAR----
MSMEG_6263|M.smegmatis_MC2_155      ARVPLAGTDWIPGRGAAL--------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           IGNVNRTVGTMLGHELTKAYGGQG---LPDGTIDITFDGSAGNSFGAFVP
Rv3859c|M.tuberculosis_H37Rv        IGNVNRTVGTMLGHELTKAYGGQG---LPDGTIDITFDGSAGNSFGAFVP
MAV_0166|M.avium_104                ISNVNRTVGTMLGHEVTKAYGGQG---LPDGTIDITFDGSAGNSFGAFVP
MLBr_00061|M.leprae_Br4923          IGNVNRTVGTMLGHELTKAYGAQG---LPDGTIDITFEGSAGNSFGAFVP
MAB_2486c|M.abscessus_ATCC_199      AIDIERSLNYQNIEGPAVATDERGRRYLLPESIAITTTGSAGQSYGVFCN
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          PNQATE--------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       PNQATE--------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           KGITLRVYGDANDYVGKGLSGGRIVVRPSDDAPQDYVAEDNIIGGNVILF
Rv3859c|M.tuberculosis_H37Rv        KGITLRVYGDANDYVGKGLSGGRIVVRPSDDAPQDYVAEDNIIGGNVILF
MAV_0166|M.avium_104                RGITLRVYGDANDYVGKGLSGGRIVVRPSDNAPADYVAEDNIIGGNVILF
MLBr_00061|M.leprae_Br4923          KGITLRVYGDANDYVGKGLSGGRIVVRPSDSVPLNYVAEDNIIGGNVILF
MAB_2486c|M.abscessus_ATCC_199      DGMVLTHTGTCNDGVGKSACGGTITVRSPGGGSSE--PGGNVLIGNFALF
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           GATSGEVYLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGRT
Rv3859c|M.tuberculosis_H37Rv        GATSGEVYLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGRT
MAV_0166|M.avium_104                GATSGEAYLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGKVVVLGRT
MLBr_00061|M.leprae_Br4923          GATSGEVYLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGKVVILGRT
MAB_2486c|M.abscessus_ATCC_199      GASGGRLFVQGQAGDRFAVRNSGATAVVEGTGEFLCEYMTNGAVLNIGDF
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           GRNFAAGMSGGVAYVYDPDGELPANLNSEMVELETLDED--DADWLHGTI
Rv3859c|M.tuberculosis_H37Rv        GRNFAAGMSGGVAYVYDPDGELPANLNSEMVELETLDED--DADWLHGTI
MAV_0166|M.avium_104                GRNFAAGMSGGVAYIYDPPGEFPQHLNAEMVELESLDDD--DIEWLHGMI
MLBr_00061|M.leprae_Br4923          GRNFAAGMSGGEAYVYDSDGELPANLNFEMVELEPLDFD--DAAWLYATI
MAB_2486c|M.abscessus_ATCC_199      GKGVANGMSGGFLYQYDPHGQLPSKVSHDSVLVLPITDAPFHEAAAHILL
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           QVHVDATDSAVGQRILSDWSGQQRHFVKVMPRDYKRVLQAIALAE-RDGV
Rv3859c|M.tuberculosis_H37Rv        QVHVDATDSAVGQRILSDWSGQQRHFVKVMPRDYKRVLQAIALAE-RDGV
MAV_0166|M.avium_104                QAHVDATDSAVGQRILGDWAQQQRHFVKVMPRDYKRVLQAIAEAE-RDGG
MLBr_00061|M.leprae_Br4923          QAHVDATDSAVGQRILAGWSEQQRYFVKVMPKDYKRVLQAIALAE-RNGV
MAB_2486c|M.abscessus_ATCC_199      QWHVAATGSTKGQALLDDWQSARDHMVYTMSRALLQYQDSDAILQGKTRK
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           DVDKAIMAAAHG--------------------------------------
Rv3859c|M.tuberculosis_H37Rv        DVDKAIMAAAHG--------------------------------------
MAV_0166|M.avium_104                DVDKAIMAAAHG--------------------------------------
MLBr_00061|M.leprae_Br4923          DVNKVIMEPAHG--------------------------------------
MAB_2486c|M.abscessus_ATCC_199      ELLDELTAALAGYQVHKFKLSYRDRRDVVGGTVPAYGDTDTEGMYALLNT
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           --------------------------------------------------
Rv3859c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_0166|M.avium_104                --------------------------------------------------
MLBr_00061|M.leprae_Br4923          --------------------------------------------------
MAB_2486c|M.abscessus_ATCC_199      YTVLNMAQQLALSRMPNVTDVTDPRIGKAVRNLVLTEDFFLIQKLQKYAR
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           --------------------------------------------------
Rv3859c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_0166|M.avium_104                --------------------------------------------------
MLBr_00061|M.leprae_Br4923          --------------------------------------------------
MAB_2486c|M.abscessus_ATCC_199      EAIDGYSDEDLAVLIADKRLTDYKDALSQRNVLSMDSPGTYGWILHQSAK
MMAR_1226|M.marinum_M               --------------------------------------------------
MUL_2666|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0988|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2993|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb3889c|M.bovis_AF2122/97           ---------------------------------
Rv3859c|M.tuberculosis_H37Rv        ---------------------------------
MAV_0166|M.avium_104                ---------------------------------
MLBr_00061|M.leprae_Br4923          ---------------------------------
MAB_2486c|M.abscessus_ATCC_199      NIDKIGRLPSFEELFAHRALPAVALSGPSLQTT
MMAR_1226|M.marinum_M               ---------------------------------
MUL_2666|M.ulcerans_Agy99           ---------------------------------
Mflv_0988|M.gilvum_PYR-GCK          ---------------------------------
Mvan_5847|M.vanbaalenii_PYR-1       ---------------------------------
TH_2993|M.thermoresistible__bu      ---------------------------------
MSMEG_6263|M.smegmatis_MC2_155      ---------------------------------