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TYTDDDRARLGLRESATFDRTTIAAIQRAADTGIYDIRGWGAKRPLPHFDDLLFLGASMSRYPLEGYRER CATDVVLGDRHAKHPLHLEIPVTIAGMSFGALSGPAKEALGRGASEVGTSTTTGDGGMTPEERGQSKYLV YQYLPSRYGMNPDDLRKADAIEVVLGQGAKPGGGGMLLGQKISERVAGMRTLPEGIDQRSACRHPDWTGP DDLTIKINELREITDWEKPIYVKVGATRTYYDVKLAVHAGADVVVVDGMQGGTAATQEVFIEHVGIPTLA AIPQAVQALQELGVHRTGASGATGVDGVQLIVSGGIRNGADVAKALALGADAVAIGTAALIALGDNHPRY ASEYEKLGSAAGFYDDYQDGRDPAGISTQDPELAARFDPIAGGHRLANYLRVLTMEAQTIARACGKSHVC HLEPDDLVAVSIEAAAMARVPLAGTDWIPGQRT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1297 | - | - | 100% (454) | ferredoxin-dependent glutamate synthase |
| M. gilvum PYR-GCK | Mflv_0988 | - | 4e-32 | 29.23% (366) | ferredoxin-dependent glutamate synthase |
| M. gilvum PYR-GCK | Mflv_3593 | - | 2e-23 | 28.81% (295) | glutamate synthase (ferredoxin) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3889c | gltB | 4e-21 | 27.52% (298) | putative ferredoxin-dependent glutamate synthase |
| M. tuberculosis H37Rv | Rv3859c | gltB | 4e-21 | 27.52% (298) | ferredoxin-dependent glutamate synthase |
| M. leprae Br4923 | MLBr_00061 | gltB | 6e-23 | 28.43% (299) | putative ferredoxin-dependent glutamate synthase |
| M. abscessus ATCC 19977 | MAB_0091 | - | 2e-23 | 29.10% (299) | putative ferredoxin-dependent glutamate synthase |
| M. marinum M | MMAR_1226 | gltB_1 | 3e-35 | 31.79% (346) | glutamate synthase, GltB_1 |
| M. avium 104 | MAV_0166 | - | 3e-21 | 27.85% (298) | ferredoxin-dependent glutamate synthase 1 |
| M. smegmatis MC2 155 | MSMEG_6263 | - | 0.0 | 93.36% (452) | glutamate synthase family protein |
| M. thermoresistible (build 8) | TH_2993 | - | 2e-29 | 28.65% (363) | PUTATIVE ferredoxin-dependent glutamate synthase |
| M. ulcerans Agy99 | MUL_2666 | gltB_1 | 3e-36 | 31.79% (346) | glutamate synthase, GltB_1 |
| M. vanbaalenii PYR-1 | Mvan_5512 | - | 0.0 | 94.47% (452) | ferredoxin-dependent glutamate synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 --MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLNLEHR
Rv3859c|M.tuberculosis_H37Rv --MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLNLEHR
MAV_0166|M.avium_104 MHMTPKRAGLYNPAFEHDACGVAMVVDMHGRRSRDIVDKAITALLNLEHR
MLBr_00061|M.leprae_Br4923 --MTAKRVGLYNPAFEHDSCGVAMVVDMYGRRTRDIVDKAITALLNLEHR
MAB_0091|M.abscessus_ATCC_1997 --MPHPATGLYNPAYEHDSCGVAMVVDMHGRRSRDIVDKAITALLNLEHR
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 GAQGAEPRSGDGAGILIQVPDEFLREAVD----FELPAPGSYATGIAFLP
Rv3859c|M.tuberculosis_H37Rv GAQGAEPRSGDGAGILIQVPDEFLREAVD----FELPAPGSYATGIAFLP
MAV_0166|M.avium_104 GAQGAEPRSGDGAGILIQVPDAFLREVVD----FELPPEGSYATGIAFLP
MLBr_00061|M.leprae_Br4923 GAQGAEPRSGDGAGILIQVPDAFLRAVVD----FELPAASSYATGIAFLP
MAB_0091|M.abscessus_ATCC_1997 GAAGAEPNSGDGAGIMLQIPDKFFRAVLAEQGSFELPAEGSYASGIAFLP
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 QSSKDAAAACAAVQKIAEAEGLQVLGWRSVPTDDSSLGALSRDAMPTFRQ
Rv3859c|M.tuberculosis_H37Rv QSSKDAAAACAAVQKIAEAEGLQVLGWRSVPTDDSSLGALSRDAMPTFRQ
MAV_0166|M.avium_104 QSSKDAATACAAVEKIAEAEGLTVLGWRNVPTDDSSLGALSRDAMPTFRQ
MLBr_00061|M.leprae_Br4923 QSSKDAAAACAAVEKIAVAEGLHVLGWRNVPTDASSLGALSRDAMPTFRQ
MAB_0091|M.abscessus_ATCC_1997 QGSKDAATACEAVEKIVEAEGLTVLGWREVPHDDSSLGALARDAMPTFRQ
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 VFLAGASGMALERRCYVVRKRAEHELGTKGPGQDGPGRETVYFPSLSGQT
Rv3859c|M.tuberculosis_H37Rv VFLAGASGMALERRCYVVRKRAEHELGTKGPGQDGPGRETVYFPSLSGQT
MAV_0166|M.avium_104 VFMAGASGMTLERRAYLVRKRAEHELGTKGPGQDGPGRETVYFPSLSGQT
MLBr_00061|M.leprae_Br4923 VFMAGATGLTLERRAYVIRKRAEHELGTKGPGQDGPGRETIYFPSLSSQT
MAB_0091|M.abscessus_ATCC_1997 LFIAGASGIDLERRVYVVRKRIEHELGNQGSGRGSLGEETVYFPSLSGRT
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 LVYKGMLTTPQLKAFYLDLQDERLTSALGIVHSRFSTNTFPSWPLAHPFR
Rv3859c|M.tuberculosis_H37Rv LVYKGMLTTPQLKAFYLDLQDERLTSALGIVHSRFSTNTFPSWPLAHPFR
MAV_0166|M.avium_104 FVYKGMLTTPQLKAFYLDLQDDRLTSALGIVHSRFSTNTFPSWPLAHPFR
MLBr_00061|M.leprae_Br4923 FVYKGMLTTPQLKAFYRDLQDERLTSALGIVHSRFSTNTFPSWPLAHPFR
MAB_0091|M.abscessus_ATCC_1997 FVYKGMLTTPQLRAFYLDLQDERVESALGIVHSRFSTNTFPSWPLAHPYR
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 RIAHNGEINTVTGNENWMRAREALIKTDIFGSAADVEKLFPICTPGASDT
Rv3859c|M.tuberculosis_H37Rv RIAHNGEINTVTGNENWMRAREALIKTDIFGSAADVEKLFPICTPGASDT
MAV_0166|M.avium_104 RIAHNGEINTVTGNENWMRAREALIKTDVFGTEADVEKLFPICTPGASDT
MLBr_00061|M.leprae_Br4923 RIAHNGEINTVTGNENWMRAREALMKTDIFGSKADMEKLFPICTPGASDT
MAB_0091|M.abscessus_ATCC_1997 RVAHNGEINTVAGNENWMRAREALIKTDVFGDPAQLEKIFPICTRGASDT
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 ARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPARRAFYQYHASLM
Rv3859c|M.tuberculosis_H37Rv ARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPARRAFYQYHASLM
MAV_0166|M.avium_104 ARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPARRAFYQYHASLM
MLBr_00061|M.leprae_Br4923 ARFDEALELLHLGGRSLVHAVLMMIPEAWERHESMDPARRAFYQYHASLM
MAB_0091|M.abscessus_ATCC_1997 ARFDEALELLHLGGRPLHHAVLMMIPEAWERHENMSAELRSFYEFHASLM
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 EPWDGPASMTFTDGTVVGAVLDRNGLRPSRIWVTDDGLVVMASEAGVLDL
Rv3859c|M.tuberculosis_H37Rv EPWDGPASMTFTDGTVVGAVLDRNGLRPSRIWVTDDGLVVMASEAGVLDL
MAV_0166|M.avium_104 EPWDGPASMTFTDGTVIGAVLDRNGLRPSRIWVTEDGLVVMASEAGVLDL
MLBr_00061|M.leprae_Br4923 EPWDGPASMTFTDGVVVGAVLDRNGLRPSRIWITDAGLVVMASEAGVLDL
MAB_0091|M.abscessus_ATCC_1997 EPWDGPASVCFTDGTIVGAVLDRNGLRPSRVWVTNDGLVVMASEAGVLDL
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 HPSTVVRRMRLQPGRMFLVDTAQGRIVSDEEIKADLAAEHPYQEWLDNGL
Rv3859c|M.tuberculosis_H37Rv HPSTVVRRMRLQPGRMFLVDTAQGRIVSDEEIKADLAAEHPYQEWLDNGL
MAV_0166|M.avium_104 DPATVVRRMRLQPGRMFLVDTAQGRIVSDEEIKAELAAEHPYQEWLDRNL
MLBr_00061|M.leprae_Br4923 DPSIVVRRMRLQPGRMFLVDTAQGRIVSDEEIKAKLAAEHPYQEWLDKGL
MAB_0091|M.abscessus_ATCC_1997 DPSTVVQRTRLQPGRMFLVDTTQGRIVSDEEVKAELAAAEPYQRWLEEGL
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 VPLDELPEGKDVRMPHHRIVMRQLAFGYTYEELNLLVAPMARLGAEPIGS
Rv3859c|M.tuberculosis_H37Rv VPLDELPEGKDVRMPHHRIVMRQLAFGYTYEELNLLVAPMARLGAEPIGS
MAV_0166|M.avium_104 VPLDDLPQGDYKRMPHDRLVKRQQTFGYTYEELNLLVAPMVRTGAEPIGS
MLBr_00061|M.leprae_Br4923 VPIDELPAGKYVRMPHHRLVMRQLAFGYTYEELNLLVAPMVRAGSEPIGS
MAB_0091|M.abscessus_ATCC_1997 VRLEQLPDRPHQHMPHNRIVLRQQVFGYTYEEINLLVAPMARTGAEALGS
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 MGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPPLDAIREEVVTSLQGTTGG
Rv3859c|M.tuberculosis_H37Rv MGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPPLDAIREEVVTSLQGTTGG
MAV_0166|M.avium_104 MGTDTPVAVLSQRPRMLYDYFQQLFAQVTNPPLDAIREEVVTSLQGTTGG
MLBr_00061|M.leprae_Br4923 MGADTPIAVLSRRPRMLYDYFHQLFAQVTNPPLDAIREEVVTSLQGTTGG
MAB_0091|M.abscessus_ATCC_1997 MGTDTPIAVLSNRSRMLFDYFQQLFAQVTNPPLDAIREEVVTSLGGVIGP
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 ERDLLNPDENSCHQIVLPQPILRNHELAKLVSLDPNDKVNGRPHGLRSKV
Rv3859c|M.tuberculosis_H37Rv ERDLLNPDQNSCHQIVLPQPILRNHELAKLVSLDPNDKVNGRPHGLRSKV
MAV_0166|M.avium_104 ERDLLTPTELSCHQIVLSQPILRNRELAKLVNLNPDDEVNGRPHGMRSKV
MLBr_00061|M.leprae_Br4923 EYDLLSPDENSCHQIWLPQPILRNYELAKLVNLDPADEVNGRPHGMRSTV
MAB_0091|M.abscessus_ATCC_1997 EGDLLHPTAESCHQILLPQPVLHNDELDKLIHLDPADTVNGRAHGFSSRV
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 IRCLYRVSEGGAGLAAALEEVRGAAAAAIADGARIIILSDRESDEEMAPI
Rv3859c|M.tuberculosis_H37Rv IRCLYRVSEGGAGLAAALEEVRGAAAAAIADGARIIILSDRESDEEMAPI
MAV_0166|M.avium_104 IRCLYPVAEGGAGLAAALEDVRAQASAAIADGARVIILSDRESDEKMAPI
MLBr_00061|M.leprae_Br4923 VSCLYPVADAGAGLAAALTEVRAQASAAIVGGARVIILSDRNSDEQMAPI
MAB_0091|M.abscessus_ATCC_1997 IRCLYPVAEGGAGLRTALESVRAEVSAAIAGGAQVIILSDRESDDLMAPI
MMAR_1226|M.marinum_M ------------------MKP--RSVAAVLGGGMAGVAGWDLWQRRHAIL
MUL_2666|M.ulcerans_Agy99 ------------------MKP--RSVAAVLGGGMAGVAGWDLWQRRHAIL
TH_2993|M.thermoresistible__bu ------------------MSSLFRTAAATAASALAAVAVHDVFQRRRAIL
Mflv_1297|M.gilvum_PYR-GCK -----------MTYTDDDRARLGLRESAT---------------------
MSMEG_6263|M.smegmatis_MC2_155 -----------MSYTTDDRARLGLRESAT---------------------
Mvan_5512|M.vanbaalenii_PYR-1 -----------MSYSSDDRARLGLRESAT---------------------
Mb3889c|M.bovis_AF2122/97 PSLLAVAGVHHHLVRERTRTQVGLVVESGDAREVHHMAALVGFGAAAINP
Rv3859c|M.tuberculosis_H37Rv PSLLAVAGVHHHLVRERTRTQVGLVVESGDAREVHHMAALVGFGAAAINP
MAV_0166|M.avium_104 PSLLAVAGVHHHLVRDRTRTHVGLVVESGDAREVHHMAALVGFGAAAINP
MLBr_00061|M.leprae_Br4923 PSLLSVAAVHHHLVRDRTRTHVGLVVESGDAREVHHMAALIGFGAAAVNP
MAB_0091|M.abscessus_ATCC_1997 PSLLAVAAVHHHLVRERSRTKVGLVVEAGDAREVHHVAALVGFGAAAVNP
MMAR_1226|M.marinum_M RNFPIIGHLRFLLEAVGPELRQYIVTDNNE--------------------
MUL_2666|M.ulcerans_Agy99 RNFPIIGHLRFLLEAVGPELRQYIVTDNNE--------------------
TH_2993|M.thermoresistible__bu RNFPVIGHARYLLESIGPELRQYIVAGDDE--------------------
. : :
Mflv_1297|M.gilvum_PYR-GCK ----------FDRTTIAAIQR---------AADTGIYDIRG-WGAKRPLP
MSMEG_6263|M.smegmatis_MC2_155 ----------FDRTTIAAIQR---------AADTGIYDIRG-WGAKRPLP
Mvan_5512|M.vanbaalenii_PYR-1 ----------FDRATIAAIQR---------AADTGIYDIRG-WGAKRPLP
Mb3889c|M.bovis_AF2122/97 YLVFESIEDMLDRGVIEGIDRTAALNNYIKAAGKGVLKVMSKMGISTLAS
Rv3859c|M.tuberculosis_H37Rv YLVFESIEDMLDRGVIEGIDRTAALNNYIKAAGKGVLKVMSKMGISTLAS
MAV_0166|M.avium_104 YMVFESIEDMLDRGVIEGIDRNTALNNYVKAAGKGVLKVMSKMGISTLAS
MLBr_00061|M.leprae_Br4923 YLVFESIEEMLDRGVIDGIDRKTALNNYIKATGQGVLKIMSKMGISTLAS
MAB_0091|M.abscessus_ATCC_1997 YMAFESIEDLIDRGVITGVDRDKAIRNYIKAAGKGVLKVMSKMGISTLAS
MMAR_1226|M.marinum_M -----------ERPFSRDQRR------WVYTSSKLTNRYFGFGTDNDLER
MUL_2666|M.ulcerans_Agy99 -----------ERPFSRDQRR------WVYTSSKLTNRYFGFGTDNDLER
TH_2993|M.thermoresistible__bu -----------ERPFTRDQRR------WVYASAKQENNYFSFGTDNDIEY
:* * :: . .
Mflv_1297|M.gilvum_PYR-GCK HFDDLLFLGASMSRYPLEGYR-----------------------------
MSMEG_6263|M.smegmatis_MC2_155 HFDDLLFLGASMSRYPLEGYR-----------------------------
Mvan_5512|M.vanbaalenii_PYR-1 HFDDLLFLGASMSRYPLEGYR-----------------------------
Mb3889c|M.bovis_AF2122/97 YTGAQLFQAVGISEQVLDEYFTGLTCPTGGITLDDIAADVAARHRLAYLD
Rv3859c|M.tuberculosis_H37Rv YTGAQLFQAVGISEQVLDEYFTGLTCPTGGITLDDIAADVAARHRLAYLD
MAV_0166|M.avium_104 YTGAQLFQAVGISEDVLDEYFTGLSCPIGGITLDDIAADVAARHALAYLD
MLBr_00061|M.leprae_Br4923 YVGAQLFQAVGISEDVLDEYFSGLSCPTGGITLDDIAAEVAVRHRVAYLD
MAB_0091|M.abscessus_ATCC_1997 YTGAQLFQAIGLSQELLDEYFTGLACPTGGIGLDEIAADVASRHNLAFLD
MMAR_1226|M.marinum_M AHNYPIIKHAAFPVSAPDGEPAH--------------------------P
MUL_2666|M.ulcerans_Agy99 AHNYPIIKHAAFPVSAPDGEPAH--------------------------P
TH_2993|M.thermoresistible__bu TSGYPVIRHRTFGRSIPASAPR---------------------------A
. :: :
Mflv_1297|M.gilvum_PYR-GCK ---ERCATDVVLG-------------------------DRHAKHPLHLEI
MSMEG_6263|M.smegmatis_MC2_155 ---ERCGTDVVLG-------------------------DRHAKHPLHLDI
Mvan_5512|M.vanbaalenii_PYR-1 ---ERCATDVVLG-------------------------DRFAKHPLHLDI
Mb3889c|M.bovis_AF2122/97 RPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHSTRTGQYKIFKEY
Rv3859c|M.tuberculosis_H37Rv RPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHSTRTGQYKIFKEY
MAV_0166|M.avium_104 RPNERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHATRTGQYKIFKDY
MLBr_00061|M.leprae_Br4923 RPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHATRSGQYKIFKEY
MAB_0091|M.abscessus_ATCC_1997 RPEEWAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHSTRTGQYSVFKEY
MMAR_1226|M.marinum_M DPAVALPAAKVLG-------------------------GARGRAKAFRPS
MUL_2666|M.ulcerans_Agy99 DPAVALPAAKVLG-------------------------GARGRAKAFRPS
TH_2993|M.thermoresistible__bu ALDVELPAAKVIG-------------------------AARNRAQAFRPQ
:* : .
Mflv_1297|M.gilvum_PYR-GCK P-----------------------------------------VTIAGMSF
MSMEG_6263|M.smegmatis_MC2_155 P-----------------------------------------VTIAGMSF
Mvan_5512|M.vanbaalenii_PYR-1 P-----------------------------------------VTIAGMSF
Mb3889c|M.bovis_AF2122/97 TRLVDDQSERMASLRGLLKFRTGVRPPVPLDEVEPASEIVKRFSTGAMSY
Rv3859c|M.tuberculosis_H37Rv TRLVDDQSERMASLRGLLKFRTGVRPPVPLDEVEPASEIVKRFSTGAMSY
MAV_0166|M.avium_104 TRLVDDQSERMASLRGLLKFRAGVRPPVPLEEVEPASEIVKRFSTGAMSY
MLBr_00061|M.leprae_Br4923 TRLVDDQSERMASLRGLLKFRSGVRTPVPLDEVEPASEIVKRFSTGAMSY
MAB_0091|M.abscessus_ATCC_1997 TQLVDDQSERMASLRGLLKFKTGVRPPVPLDEVEPASEIVKRFSTGAMSF
MMAR_1226|M.marinum_M S----------------------------------------LVNISGMSY
MUL_2666|M.ulcerans_Agy99 S----------------------------------------LVNISGMSY
TH_2993|M.thermoresistible__bu S----------------------------------------VVNIGAMSF
. .. ..**:
Mflv_1297|M.gilvum_PYR-GCK GALSGPAKEALGRGASEVGTSTTTGDGG-----MTPEERGQSK-YLVYQY
MSMEG_6263|M.smegmatis_MC2_155 GALSAGAKEALGRGASEVGTSTTTGDGG-----MTPEERGQSK-HLVYQY
Mvan_5512|M.vanbaalenii_PYR-1 GALSGPAKEALGRGASEVGTSTTTGDGG-----MTPEERGQSK-YLVYQY
Mb3889c|M.bovis_AF2122/97 GSISAEAHETLAIAMNRLGARSNCGEGGEDVKRFDRDPNGDWRRSAIKQV
Rv3859c|M.tuberculosis_H37Rv GSISAEAHETLAIAMNRLGARSNCGEGGEDVKRFDRDPNGDWRRSAIKQV
MAV_0166|M.avium_104 GSISAEAHETLAIAMNRLGGRSNSGEGGEDVKRFDRDPDGSWRRSAIKQV
MLBr_00061|M.leprae_Br4923 GSISAEAHETLAIAMNRLGGRSNSGEGGEDVNRFEPDPNGDWRRSAIKQV
MAB_0091|M.abscessus_ATCC_1997 GSISAEAHETLAIAMNRLGGRSNSGEGGEDPRRFTPDENGDWRRSAIKQV
MMAR_1226|M.marinum_M GALGGAAISALNQGAAIAGALHTTGEGAVSPYHLNGGDLVWQIGTGYFGC
MUL_2666|M.ulcerans_Agy99 GALGGAAISALNQGAGIAGALHTTGEGAVSPYHLNGGDLVWQIGTGYFGC
TH_2993|M.thermoresistible__bu GSLSGKAIEALNRGAALAGCLHNTGEGGISRYHRHGGELIFQIGTAYFGC
*::.. * .:* . * . *:*.
Mflv_1297|M.gilvum_PYR-GCK LPSRYGMNPDDLRK-------ADAIEVVLGQGAKPGGGGMLLGQKISERV
MSMEG_6263|M.smegmatis_MC2_155 LPSRYGMNPDDLRK-------ADAIEVVLGQGAKPGGGGMLLGQKISERV
Mvan_5512|M.vanbaalenii_PYR-1 LPSRYGMNPEDLRK-------ADAIEIVLGQGAKPGGGGMLLGQKISERV
Mb3889c|M.bovis_AF2122/97 ASARFGVTSHYLTN-------CTDLQIKMAQGAKPGEGGQLPGHKVYPWV
Rv3859c|M.tuberculosis_H37Rv ASARFGVTSHYLTN-------CTDLQIKMAQGAKPGEGGQLPGHKVYPWV
MAV_0166|M.avium_104 ASGRFGVTSHYLTN-------CTDIQIKMAQGAKPGEGGQLPGHKVYPWV
MLBr_00061|M.leprae_Br4923 ASARFGVTSHYLTN-------CTDIQIKMAQGAKPGEGGQLPGRKVYPWI
MAB_0091|M.abscessus_ATCC_1997 ASGRFGVTSHYLSN-------CTDIQIKMAQGAKPGEGGQLPAHKVYPWV
MMAR_1226|M.marinum_M RNDDGTFSLSRLIDRVAATPSIRAIEIKLSQGAKPGLGGMLPGAKVTADI
MUL_2666|M.ulcerans_Agy99 RNDDGTFSLSRLIDRVAATTSIRAIEIKLSQGAKPGLGGMLPGAKVTADI
TH_2993|M.thermoresistible__bu RDAEGRFDLARLKDLVAGAP-VRALEIKLSQGAKPTLGGVLPAAKVSAEI
. * . ::: :.***** ** * . *: :
Mflv_1297|M.gilvum_PYR-GCK AGMRTLPEGIDQRSACRHPDWTGPDDLTIKINELREITDWEKPIYVKVGA
MSMEG_6263|M.smegmatis_MC2_155 AGMRTLPQGIDQRSACRHPDWTGPDDLTIKINELREITDWEKPIYVKVGA
Mvan_5512|M.vanbaalenii_PYR-1 AGMRTLPEGIDQRSACRHPDWTGPDDLTIKINELREITDWEKPIYVKVGA
Mb3889c|M.bovis_AF2122/97 AEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVKLVSE
Rv3859c|M.tuberculosis_H37Rv AEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVKLVSE
MAV_0166|M.avium_104 AEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPAARVHVKLVSE
MLBr_00061|M.leprae_Br4923 AQVRNSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVKLVSE
MAB_0091|M.abscessus_ATCC_1997 AEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNSNPQARIHVKLVSE
MMAR_1226|M.marinum_M AAIRGIPVGVDCKSPAGHSAFADIDGMLELVETIADATGLPVGIKSAVGE
MUL_2666|M.ulcerans_Agy99 AAIRGIPVGVDCKSPAGHSAFADIDGMLELVETIADATGLPVGIKSAVGE
TH_2993|M.thermoresistible__bu AATRGIPEGRDCVSPSRHAEFTDADSMLDWVEMLAAETGLPVGIKSAVGD
* * . * . *. * . :.: :. : . *.
Mflv_1297|M.gilvum_PYR-GCK TRTYYDVKLAVHAG---ADVVVVDGMQGGTAATQEVFIEHVGIPTLAAIP
MSMEG_6263|M.smegmatis_MC2_155 TRTYYDVKLAVHSG---ADVVVVDGMQGGTAATQEVFIEHVGIPTLAAIP
Mvan_5512|M.vanbaalenii_PYR-1 SRTYYDVKLAVHAG---ADVVVVDGMQGGTAATQEVFIEHVGIPTLAAIP
Mb3889c|M.bovis_AF2122/97 NGVGTVAAGVSKAH---ADVVLISGHDGGTGATPLTSMKHAGAPWELGLA
Rv3859c|M.tuberculosis_H37Rv NGVGTVAAGVSKAH---ADVVLISGHDGGTGATPLTSMKHAGAPWELGLA
MAV_0166|M.avium_104 NGVGTVAAGVSKAH---ADVVLISGHDGGTGATPLTSMKHAGAPWELGLA
MLBr_00061|M.leprae_Br4923 NGVGTVAAGVSKAH---ADVVLVSGHDGGTGATPLTSMKHSGAPWELGLA
MAB_0091|M.abscessus_ATCC_1997 NGVGTVATGVSKAH---ADVVLISGHDGGTGATPLTSMKHAGAPWELGLA
MMAR_1226|M.marinum_M GLFWPQLAARMARTGRGVDFVTVDGGEGGTGAAPLVFSDHVALPFKWAFP
MUL_2666|M.ulcerans_Agy99 GLFWPQLAARMARTGRGVDFVTVDGGEGGTGAAPLVFSDHVALPFKWAFP
TH_2993|M.thermoresistible__bu LDFWEQLTDLMRDTGRGVDFVSIDGGEGGTGAAPLIFTDTVSLPFQLGFA
.*.* :.* :***.*: . . * .:.
Mflv_1297|M.gilvum_PYR-GCK QAVQALQELGVHRTGASGATGVDGVQLIVSGGIRNGADVAKALALGADAV
MSMEG_6263|M.smegmatis_MC2_155 QAVQALQELGVHRK----------VQLIVSGGIRNGADVAKALALGADAV
Mvan_5512|M.vanbaalenii_PYR-1 QAVQALQELGVHRK----------VQLIVSGGIRNGADVAKALALGADAV
Mb3889c|M.bovis_AF2122/97 ETQQTLLLNGLRDR----------IVVQVDGQLKTGRDVMIATLLGAEEF
Rv3859c|M.tuberculosis_H37Rv ETQQTLLLNGLRDR----------IVVQVDGQLKTGRDVMIATLLGAEEF
MAV_0166|M.avium_104 ETQQTLLLNGLRDR----------IVVQVDGQLKTGRDVMIAALLGAEEF
MLBr_00061|M.leprae_Br4923 ETQQTLLLNGLRDR----------IVVQVDGQLKTGRDVMIAALLGAEEF
MAB_0091|M.abscessus_ATCC_1997 ETQQTLLLNGLRDR----------IVVQVDGQLKTGRDVMIAMLLGGEEF
MMAR_1226|M.marinum_M RVFRAFAEEDLHHD----------VVFIGSAKLGIPENALLALTMGVDMI
MUL_2666|M.ulcerans_Agy99 RVFRAFAEEDLHHD----------VVFIGSAKLGIPENALLALAMGADMI
TH_2993|M.thermoresistible__bu EVYRIFAERGLHEQ----------VTFIGSGKLGLPDNAVVAFALGCDMV
.. : : .:: : . .. : :. * :* : .
Mflv_1297|M.gilvum_PYR-GCK AIGTAALIALG---------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 AIGTAALIALG---------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 AIGTAALIALG---------------------------------------
Mb3889c|M.bovis_AF2122/97 GFATAPLVVAGCIMMRVCHLDTCPVGVATQNPLLRERFTGKPEFVENFFM
Rv3859c|M.tuberculosis_H37Rv GFATAPLVVAGCIMMRVCHLDTCPVGVATQNPLLRERFTGKPEFVENFFM
MAV_0166|M.avium_104 GFATAPLVVSGCIMMRVCHLDTCPVGVATQNPVLRERFTGKPEFVENFFM
MLBr_00061|M.leprae_Br4923 GFATAPLVVAGCIMMRVCHLDTCPVGVATQNPLLRKRFNGKPEFVENFFM
MAB_0091|M.abscessus_ATCC_1997 GFATAPLVVSGCIMMRVCHLDTCPVGVATQNPVLRQRFNGKPEFVENFFL
MMAR_1226|M.marinum_M NVGRTAMFAIG---------------------------------------
MUL_2666|M.ulcerans_Agy99 NVGRTAMFAIG---------------------------------------
TH_2993|M.thermoresistible__bu YAARESMLALG---------------------------------------
. .:.. *
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 FIAEEVREYLAQLGFRTVNEAVGQAGALDTTLARAHWKAHKLDLAPVLHE
Rv3859c|M.tuberculosis_H37Rv FIAEEVREYLAQLGFRTVNEAVGQAGALDTTLARAHWKAHKLDLAPVLHE
MAV_0166|M.avium_104 FIAEEVREYMAQLGFRTLNEAVGQVKSLDTTLARAHWKAHRLDLGPVLHE
MLBr_00061|M.leprae_Br4923 FIAEEVREYMAQLGFRTFNEAVGQVGALDTTPVREHWKAHSIDLTPVLHE
MAB_0091|M.abscessus_ATCC_1997 FIAEEVRELMAELGFRTVNEAVGQVGALDIERAVAHWKASKIDLTPVLTE
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------DNHPRYASEYEK
MSMEG_6263|M.smegmatis_MC2_155 --------------------------------------DNHPRYAAEYEK
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------DNHPRYAAEYEK
Mb3889c|M.bovis_AF2122/97 PESAFMNQDLYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTIGN
Rv3859c|M.tuberculosis_H37Rv PESAFMNQDLYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTIGN
MAV_0166|M.avium_104 PESAFMNQDLYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTISN
MLBr_00061|M.leprae_Br4923 PESAFMNQDLYCSSRQDHGLDKVLDQQLIAVSRDALDFGKPVRFSTTIGN
MAB_0091|M.abscessus_ATCC_1997 PESAFMNQDLYCSGSQDHGLEKALDQQLIVMSREALDHGTPVKFETLITN
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mflv_1297|M.gilvum_PYR-GCK LGSAAGFYDDYQDGRDPAGISTQDPELAARFDPIAG--------------
MSMEG_6263|M.smegmatis_MC2_155 IGSAAGFYDDFQDGRDPAGISTQDAELAARFDPIEG--------------
Mvan_5512|M.vanbaalenii_PYR-1 LGSAAGFFDDFQDGRDPAGISTQDPELAARFDPIAG--------------
Mb3889c|M.bovis_AF2122/97 VNRTVGTMLGHELTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPKGITLR
Rv3859c|M.tuberculosis_H37Rv VNRTVGTMLGHELTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPKGITLR
MAV_0166|M.avium_104 VNRTVGTMLGHEVTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPRGITLR
MLBr_00061|M.leprae_Br4923 VNRTVGTMLGHELTKAYGAQGLPDGTIDITFEGSAGNSFGAFVPKGITLR
MAB_0091|M.abscessus_ATCC_1997 VNRTVGTMLGHEVTKAYGGEGLPDDTIDITFTGSAGNSFGAFVPRGITLR
MMAR_1226|M.marinum_M ----CIQAQRCHTGRCPSGVATQSAWLQHGLDPALK--------------
MUL_2666|M.ulcerans_Agy99 ----CIQAQRCHTGRCPSGVATQSAWLQHGLDPALK--------------
TH_2993|M.thermoresistible__bu ----CIQAKKCHTDTCPTGVATQNAWLTRGLVPDDK--------------
. . . . : :
Mflv_1297|M.gilvum_PYR-GCK ---------GHRLAN-----------------------------------
MSMEG_6263|M.smegmatis_MC2_155 ---------GRRLAN-----------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 ---------GHRLAN-----------------------------------
Mb3889c|M.bovis_AF2122/97 VYGDANDYVGKGLSGGRIVVRPSDDAPQDYVAEDNIIGGNVILFGATSGE
Rv3859c|M.tuberculosis_H37Rv VYGDANDYVGKGLSGGRIVVRPSDDAPQDYVAEDNIIGGNVILFGATSGE
MAV_0166|M.avium_104 VYGDANDYVGKGLSGGRIVVRPSDNAPADYVAEDNIIGGNVILFGATSGE
MLBr_00061|M.leprae_Br4923 VYGDANDYVGKGLSGGRIVVRPSDSVPLNYVAEDNIIGGNVILFGATSGE
MAB_0091|M.abscessus_ATCC_1997 LFGDANDYVGKGLSGGHIVVRPSREAPEGFVAEKNIIGGNVILFGATSGE
MMAR_1226|M.marinum_M ---------AVRCAN-----------------------------------
MUL_2666|M.ulcerans_Agy99 ---------AVRCAN-----------------------------------
TH_2993|M.thermoresistible__bu ---------APRVAN-----------------------------------
. :.
Mflv_1297|M.gilvum_PYR-GCK -YLR--------VLTMEAQTIARACGKSHVCHLEPDDLVAVSIEAAAMAR
MSMEG_6263|M.smegmatis_MC2_155 -YLR--------VLTMEAQTIARACGKAHVCHLEPEDLVAVTIEAAAMAR
Mvan_5512|M.vanbaalenii_PYR-1 -YLR--------VLTMEAQTIARACGKSHVCHLEPDDLVAVSIEAAAMAR
Mb3889c|M.bovis_AF2122/97 VYLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGRTGRNFAA
Rv3859c|M.tuberculosis_H37Rv VYLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGRTGRNFAA
MAV_0166|M.avium_104 AYLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGKVVVLGRTGRNFAA
MLBr_00061|M.leprae_Br4923 VYLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGKVVILGRTGRNFAA
MAB_0091|M.abscessus_ATCC_1997 AFLNGVVGERFAVRNSGAAAVVEGVGDHGCEYMTGGTVVVLGPTGRNFAA
MMAR_1226|M.marinum_M -YLA--------TLRFELLSLARACGYVHPALVPLQAIELLDVDLQTVQV
MUL_2666|M.ulcerans_Agy99 -YLA--------TLRFELLSLARACGYVHPALVPLQAIELLDVDLQTVQV
TH_2993|M.thermoresistible__bu -YIR--------TLRRDLVKVAEACGVEHPGLISGDLIDILDGHTSARSL
:: . :... * : : :
Mflv_1297|M.gilvum_PYR-GCK VPLAGTDWIPGQRT------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 VPLAGTDWIPGRGAAL----------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 IPLAGTDWIPGRNGGAW---------------------------------
Mb3889c|M.bovis_AF2122/97 GMSGGVAYVYDPDGELPANLNSEMVELETLDEDDADWLHGTIQVHVDATD
Rv3859c|M.tuberculosis_H37Rv GMSGGVAYVYDPDGELPANLNSEMVELETLDEDDADWLHGTIQVHVDATD
MAV_0166|M.avium_104 GMSGGVAYIYDPPGEFPQHLNAEMVELESLDDDDIEWLHGMIQAHVDATD
MLBr_00061|M.leprae_Br4923 GMSGGEAYVYDSDGELPANLNFEMVELEPLDFDDAAWLYATIQAHVDATD
MAB_0091|M.abscessus_ATCC_1997 GMSGGVAYVYDPDKRLMDNLNDEMVDLDALDPDDQQVLRSLIEKHVAATD
MMAR_1226|M.marinum_M DDLFGYQPGWGIPSPADVAAITALMTK------ASPPR------------
MUL_2666|M.ulcerans_Agy99 DDLFGYQPGWGIPSPADVAAITALMTK------ASPPR------------
TH_2993|M.thermoresistible__bu YEVYGYQPGMGLPSAEDRAEILRLMADRATRGGSAPPSHSAPAR------
* .
Mflv_1297|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6263|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5512|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3889c|M.bovis_AF2122/97 SAVGQRILSDWSGQQRHFVKVMPRDYKRVLQAIALAERDGVDVDKAIMAA
Rv3859c|M.tuberculosis_H37Rv SAVGQRILSDWSGQQRHFVKVMPRDYKRVLQAIALAERDGVDVDKAIMAA
MAV_0166|M.avium_104 SAVGQRILGDWAQQQRHFVKVMPRDYKRVLQAIAEAERDGGDVDKAIMAA
MLBr_00061|M.leprae_Br4923 SAVGQRILAGWSEQQRYFVKVMPKDYKRVLQAIALAERNGVDVNKVIMEP
MAB_0091|M.abscessus_ATCC_1997 SAVGQRILADWSGHSDSFVKVMPRDYRRVLEAIADAELTGGDVNEAIMAA
MMAR_1226|M.marinum_M --------------------------------------------------
MUL_2666|M.ulcerans_Agy99 --------------------------------------------------
TH_2993|M.thermoresistible__bu --------------------------------------------------
Mflv_1297|M.gilvum_PYR-GCK ---
MSMEG_6263|M.smegmatis_MC2_155 ---
Mvan_5512|M.vanbaalenii_PYR-1 ---
Mb3889c|M.bovis_AF2122/97 AHG
Rv3859c|M.tuberculosis_H37Rv AHG
MAV_0166|M.avium_104 AHG
MLBr_00061|M.leprae_Br4923 AHG
MAB_0091|M.abscessus_ATCC_1997 ARG
MMAR_1226|M.marinum_M ---
MUL_2666|M.ulcerans_Agy99 ---
TH_2993|M.thermoresistible__bu ---