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ASGGSGRRTSSGRRTAWTRAKDSDRNETCQILDTALADGQLSMTEHGERVKSATTASTLGQLQDLVSDLQ TAKTIAEPTVITRVINRQVARPGWGVKAAIAAVLVVLGIAIGWGLYGNSSSPLSFQTDPGAKDDGIPARV LTPPRQLQSLGGFTGLFEQMRQKFGSTMGYELDIHSDMAYLDRPDPQDNRRSLTYYYRGGWGEPSGSPTA VSADERLVDLAKFDFEKILGVVRGAPETVGISRADLKETWLRISPSEDPATPDAVIVEIVVNSDFGNGRI ELYPDGTPLAIWPANR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0869 | - | - | 100% (297) | hypothetical protein Mflv_0869 |
| M. gilvum PYR-GCK | Mflv_1879 | - | 2e-05 | 39.34% (61) | hypothetical protein Mflv_1879 |
| M. gilvum PYR-GCK | Mflv_0159 | - | 2e-05 | 28.67% (143) | hypothetical protein Mflv_0159 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0049c | - | 4e-75 | 51.06% (282) | hypothetical protein Mb0049c |
| M. tuberculosis H37Rv | Rv0048c | - | 2e-75 | 51.42% (282) | hypothetical protein Rv0048c |
| M. leprae Br4923 | MLBr_00169 | - | 3e-05 | 31.94% (72) | hypothetical protein MLBr_00169 |
| M. abscessus ATCC 19977 | MAB_4904 | - | 3e-42 | 40.50% (279) | hypothetical protein MAB_4904 |
| M. marinum M | MMAR_0067 | - | 3e-79 | 53.85% (273) | hypothetical protein MMAR_0067 |
| M. avium 104 | MAV_0069 | - | 8e-79 | 54.42% (283) | hypothetical protein MAV_0069 |
| M. smegmatis MC2 155 | MSMEG_6902 | - | 1e-110 | 66.43% (286) | hypothetical protein MSMEG_6902 |
| M. thermoresistible (build 8) | TH_1268 | - | 3e-07 | 34.74% (95) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0066 | - | 7e-79 | 53.48% (273) | hypothetical protein MUL_0066 |
| M. vanbaalenii PYR-1 | Mvan_6038 | - | 1e-136 | 79.00% (300) | hypothetical protein Mvan_6038 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0869|M.gilvum_PYR-GCK MASGGSGRRTSSG--RRTAWTRAKDSDRNETCQILDTALADGQLSMTEHG
Mvan_6038|M.vanbaalenii_PYR-1 MASGSSGRRTSS--------TRAKDSDRNETCQLLDAALAEGQLSMTEHG
MSMEG_6902|M.smegmatis_MC2_155 MAT----RQTSM--------TRAKDSDRNDTCKVLDSAMAEGQLSMEEHR
Mb0049c|M.bovis_AF2122/97 MAKWLGAPLAR----GVSTATRAKDSDRQDACRILDDALRDGELSMEEHR
Rv0048c|M.tuberculosis_H37Rv MAKWLGAPLAR----GVSTATRAKDSDRQDACRILDDALRDGELSMEEHR
MMAR_0067|M.marinum_M MAKWLGASLAR----GGSAATRAKDTDRQDACQILDSALSDGQLSMEEHR
MUL_0066|M.ulcerans_Agy99 MAKWLGASLAR----GGSAATRAKDTDRQDACQILDSALSDGQLSMEEHR
MAV_0069|M.avium_104 MAKWLGTPPAGTAPPSGRASTRAKDSDRQSTCTILDNALNDGELSAEEHR
MAB_4904|M.abscessus_ATCC_1997 ------------------MATRAKDSDREATCKALDTAFGDGQISTEEHR
MLBr_00169|M.leprae_Br4923 MSNSAQRDAKGAR----DEPLRAADTDRIQIAQLLAYAAEQGRLELKDYE
TH_1268|M.thermoresistible__bu MDSG-----------HHDAHLRASDADRAAVRQLLERAVGEGMLTLDEYT
** *:** * * :* : ::
Mflv_0869|M.gilvum_PYR-GCK ERVKSATTASTLGQLQDLVSDLQTAKTI-AEPTVITRVINRQVA--RPGW
Mvan_6038|M.vanbaalenii_PYR-1 ERVKAATTAATLGQLQDLVSDLQTARSLNVDVPVITKVINRRIPGVQAGW
MSMEG_6902|M.smegmatis_MC2_155 DRLSAAMKATTLGELADLVADLQNEAAPVRLPTLKPPRIPRPSSG-SPGW
Mb0049c|M.bovis_AF2122/97 ERVSAATKAVTLGDLQRLVADLQVESAPAQMPALKSR-------AKRTEL
Rv0048c|M.tuberculosis_H37Rv ERVSAATKAVTLGDLQRLVADLQVESAPAQMPALKSR-------AKRTEL
MMAR_0067|M.marinum_M QRVATATQAVTLGDLQHLVADLQSESAPAEVPALKSR-------GQRNSL
MUL_0066|M.ulcerans_Agy99 QRVATATQAVTLGDLQQLVADLQSESAPAEVPALKSR-------GQRNSL
MAV_0069|M.avium_104 ERVSAATRAVTLGDLQTLVCDLQTGPQPPALDPSPPS-------GRVRGW
MAB_4904|M.abscessus_ATCC_1997 QRIALATRAQTLGELKGVVADLQITAHAAETPTAPPP---------RRRW
MLBr_00169|M.leprae_Br4923 DRLAKAYAATTYQELEQLRDDLPGSQVSARRGGNPNP-------------
TH_1268|M.thermoresistible__bu ERVDVALAARTRGELDKVLADLPMARRPDLAQS-----------------
:*: * * * :* : **
Mflv_0869|M.gilvum_PYR-GCK GVKAAIAAVLVVLGIAIGWGLYGNSSSPLSFQTDPGAKDDGIPARVLTPP
Mvan_6038|M.vanbaalenii_PYR-1 GIKAAIAGVLVVLGIAIGWGLYGNTPSPLNFTSDPGAKADGIPATVLTAP
MSMEG_6902|M.smegmatis_MC2_155 GFKIASAVVLVLLGIGIGWGMYGSSPTPFHVASDPGAQADGIAPEVLAAP
Mb0049c|M.bovis_AF2122/97 GLLAAAFVASVLLGVGIGWGVYGNTRSPLDFTSDPGAKPDGIAPVVLTPP
Rv0048c|M.tuberculosis_H37Rv GLLAAAFVASVLLGVGIGWGVYGNTRSPLDFTSDPGAKPDGIAPVVLTPP
MMAR_0067|M.marinum_M GLLAAALGVSILLGVAIGWGLYGNTRSPLDFTTDPGAKPDGVAAVVLTPP
MUL_0066|M.ulcerans_Agy99 GLLAAALGVSILLGVAIGWGLYGNTRSPLDFTTDPGAKPDGVAAVVLTPP
MAV_0069|M.avium_104 GTLAAAFVVSVLLGIGIGWGLYGNTSSPLDFTSDPGAKPDGVNAVVLTPP
MAB_4904|M.abscessus_ATCC_1997 PALAATAVVAAAIGAGA--GIYATRPS----APDPGAVSDGIAPVVIAPA
MLBr_00169|M.leprae_Br4923 ------APSTLLLALMSGFERRG----------------------RWNVP
TH_1268|M.thermoresistible__bu ------TQPLLLRGRFSTLSRKG----------------------EWSVP
. . .
Mflv_0869|M.gilvum_PYR-GCK RQLQSLGGFTGLFEQMRQKFGSTMGYELDIHSDMAYLDRPDPQDNRRSLT
Mvan_6038|M.vanbaalenii_PYR-1 KQLQSLGGFNGLFEQMRKKFGSTMGYELDIHSDMAFLDRPDPQDNRRSLS
MSMEG_6902|M.smegmatis_MC2_155 RQLQSLNGFNGLFDQMRKKFGNTMGYELDIHSDMAFLDRPDPSDNRREMS
Mb0049c|M.bovis_AF2122/97 RQLHSLGGLTGLLEQTRKRFGDTMGYRLVIYPEYASLDRVDPADDRRVLA
Rv0048c|M.tuberculosis_H37Rv RQLHSLGGLTGLLEQTRKRFGDTMGYRLVIYPEYASLDRVDPADDRRVLA
MMAR_0067|M.marinum_M KQLHSLGGLTGLLEQTRKRFGDTMGYRMVIYPEYAVLDRKDPADERRILS
MUL_0066|M.ulcerans_Agy99 KQLHSLGGLTGLLEQTRKRFGDTMGYRMVIYPEYAVLDRKDPADERRILS
MAV_0069|M.avium_104 TQLHSVGGLTGLLEQMRKRFGSTLGYRLVIYPTYAALDRPDPSDDRRVLA
MAB_4904|M.abscessus_ATCC_1997 K-LFSVPGLTGLLAQMRAKFGDTVGIELTIRATNASLVRIEASDPDLPIT
MLBr_00169|M.leprae_Br4923 RKLTTFSLWGSGVLDLRYADFTSTEVELHAYSVMGVQTILLPPEVNVEIS
TH_1268|M.thermoresistible__bu ARVVVDTRMCDTTLDFTVAMLRSPVVHVDIDDYLSTTTLILPDGATGDVN
: . : : .: . . :
Mflv_0869|M.gilvum_PYR-GCK YYYRGGWGEPSGSPTAVSADERLVDLAKFDFEKILGVVRGAPETVGISRA
Mvan_6038|M.vanbaalenii_PYR-1 YHYRGGWGEPTGSPSTVDADARLVDLAKFDYEKTLGILRGAPETVGIARA
MSMEG_6902|M.smegmatis_MC2_155 YTYRGGWGDPSGSPSAVDSDARLVDLSKFDYEKTLAIMRGAPDTVGIKRA
Mb0049c|M.bovis_AF2122/97 YTYRGGWGDATSSAKSIAD-VSVVDLSKFDAKTAVSIMRGAPETLGLKQS
Rv0048c|M.tuberculosis_H37Rv YTYRGGWGDATSSAKSIAD-VSVVDLSKFDAKTAVGIMRGAPETLGLKQS
MMAR_0067|M.marinum_M YTYRGGWGDPTGSARSGAD-TALVDLGKFDVKTAVGIMRGAAETLGMKPK
MUL_0066|M.ulcerans_Agy99 YTYRGGWGDPTGSARSGAD-TALVDLGKFDVKTAVGIMRGAAETLGMKPK
MAV_0069|M.avium_104 YTYRGGWGDPTSSAKSSSDGPVLVDLSKFDVTAAVGIMRGAPETLRMKPS
MAB_4904|M.abscessus_ATCC_1997 YPYQGGFRDGGAMPGTWRN-VKIGDLSRFDPTKIVGVLRGAPETLNVPTA
MLBr_00169|M.leprae_Br4923 GHGVMGSFDRQVRGQGTPG-APTVKIRGFSLWGGVGIKRKARRPRR----
TH_1268|M.thermoresistible__bu AVETFASTVNGRVPAAPPSQRLHLVIRGRVRLATVTVRYSFGAAWRRFTG
. : : : .
Mflv_0869|M.gilvum_PYR-GCK DLKETWLRISPSEDPATPDAVIVEIVVNSDFGNGRIELYPDGTPLAIWPA
Mvan_6038|M.vanbaalenii_PYR-1 DVTDSWLRISPSEDPATPDAVIIEIIVNSDFGTGRIELYPDGSTLAIWPA
MSMEG_6902|M.smegmatis_MC2_155 DVKDTWLRIGPSEDPATPEAVNVEIFVNSEFGNGRIELYPDGTTKAIWPA
Mb0049c|M.bovis_AF2122/97 DVKSMYLIVEPAKDPTTPAALSLSLYVSSDYGGGYLVFAGDGTIKHVSYP
Rv0048c|M.tuberculosis_H37Rv DVKSMYLIVEPVKDPTTPAALSLSLYVSSDYGGGYLVFAGDGTIKHVSYP
MMAR_0067|M.marinum_M DVTNMYLSINPASDPTTPGAISLQLYVSSDYGSGYIAFAGDGTIKQVNYP
MUL_0066|M.ulcerans_Agy99 DVTNMYLSINPASDPTTPGAISLQLYVSSDYGSGYIAFAGDSTIKQVNYP
MAV_0069|M.avium_104 DVKTSYLIVEPATDPTTPGALSLSVYVSSDYGGGYIAFTGDGTVKQMNLP
MAB_4904|M.abscessus_ATCC_1997 GDGGTVMVIKPSDD-----GVDITITVSDKDRTGRMLVAGNGEPKEVTPA
MLBr_00169|M.leprae_Br4923 --------------------------------------------------
TH_1268|M.thermoresistible__bu RSEP----------------------------------------------
Mflv_0869|M.gilvum_PYR-GCK NR
Mvan_6038|M.vanbaalenii_PYR-1 NR
MSMEG_6902|M.smegmatis_MC2_155 GR
Mb0049c|M.bovis_AF2122/97 S-
Rv0048c|M.tuberculosis_H37Rv S-
MMAR_0067|M.marinum_M S-
MUL_0066|M.ulcerans_Agy99 S-
MAV_0069|M.avium_104 T-
MAB_4904|M.abscessus_ATCC_1997 S-
MLBr_00169|M.leprae_Br4923 --
TH_1268|M.thermoresistible__bu --