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AKWLGASLARGGSAATRAKDTDRQDACQILDSALSDGQLSMEEHRQRVATATQAVTLGDLQQLVADLQSE SAPAEVPALKSRGQRNSLGLLAAALGVSILLGVAIGWGLYGNTRSPLDFTTDPGAKPDGVAAVVLTPPKQ LHSLGGLTGLLEQTRKRFGDTMGYRMVIYPEYAVLDRKDPADERRILSYTYRGGWGDPTGSARSGADTAL VDLGKFDVKTAVGIMRGAAETLGMKPKDVTNMYLSINPASDPTTPGAISLQLYVSSDYGSGYIAFAGDST IKQVNYPS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0066 | - | - | 100% (289) | hypothetical protein MUL_0066 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0049c | - | 1e-131 | 77.51% (289) | hypothetical protein Mb0049c |
| M. gilvum PYR-GCK | Mflv_0869 | - | 8e-79 | 53.48% (273) | hypothetical protein Mflv_0869 |
| M. tuberculosis H37Rv | Rv0048c | - | 1e-131 | 77.51% (289) | hypothetical protein Rv0048c |
| M. leprae Br4923 | MLBr_00169 | - | 5e-05 | 37.93% (58) | hypothetical protein MLBr_00169 |
| M. abscessus ATCC 19977 | MAB_4905 | - | 9e-43 | 39.05% (274) | hypothetical protein MAB_4905 |
| M. marinum M | MMAR_0067 | - | 1e-163 | 99.31% (289) | hypothetical protein MMAR_0067 |
| M. avium 104 | MAV_0069 | - | 1e-112 | 67.69% (294) | hypothetical protein MAV_0069 |
| M. smegmatis MC2 155 | MSMEG_6902 | - | 2e-77 | 50.18% (279) | hypothetical protein MSMEG_6902 |
| M. thermoresistible (build 8) | TH_1268 | - | 3e-06 | 38.33% (60) | conserved hypothetical protein |
| M. vanbaalenii PYR-1 | Mvan_6038 | - | 3e-81 | 54.35% (276) | hypothetical protein Mvan_6038 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0869|M.gilvum_PYR-GCK MASGGSGRRTSSG--RRTAWTRAKDSDRNETCQILDTALADGQLSMTEHG
Mvan_6038|M.vanbaalenii_PYR-1 MASGSSGRRTSS--------TRAKDSDRNETCQLLDAALAEGQLSMTEHG
MSMEG_6902|M.smegmatis_MC2_155 MAT----RQTSM--------TRAKDSDRNDTCKVLDSAMAEGQLSMEEHR
MUL_0066|M.ulcerans_Agy99 MAKWLGASLAR----GGSAATRAKDTDRQDACQILDSALSDGQLSMEEHR
MMAR_0067|M.marinum_M MAKWLGASLAR----GGSAATRAKDTDRQDACQILDSALSDGQLSMEEHR
Mb0049c|M.bovis_AF2122/97 MAKWLGAPLAR----GVSTATRAKDSDRQDACRILDDALRDGELSMEEHR
Rv0048c|M.tuberculosis_H37Rv MAKWLGAPLAR----GVSTATRAKDSDRQDACRILDDALRDGELSMEEHR
MAV_0069|M.avium_104 MAKWLGTPPAGTAPPSGRASTRAKDSDRQSTCTILDNALNDGELSAEEHR
MAB_4905|M.abscessus_ATCC_1997 MATRPPSQ------------TRAKDSDRDATCQALDIALGDGQLSMEEHR
MLBr_00169|M.leprae_Br4923 MSNSAQRDAKGAR----DEPLRAADTDRIQIAQLLAYAAEQGRLELKDYE
TH_1268|M.thermoresistible__bu MDSGHHDAH-----------LRASDADRAAVRQLLERAVGEGMLTLDEYT
* . ** *:** * * :* * ::
Mflv_0869|M.gilvum_PYR-GCK ERVKSATTASTLGQLQDLVSDLQTAKTI-AEPTVITRVINRQVA--RPGW
Mvan_6038|M.vanbaalenii_PYR-1 ERVKAATTAATLGQLQDLVSDLQTARSLNVDVPVITKVINRRIPGVQAGW
MSMEG_6902|M.smegmatis_MC2_155 DRLSAAMKATTLGELADLVADLQNEAAPVRLPTLKPPRIPRPSSG-SPGW
MUL_0066|M.ulcerans_Agy99 QRVATATQAVTLGDLQQLVADLQSESAPAEVPALKSR-------GQRNSL
MMAR_0067|M.marinum_M QRVATATQAVTLGDLQHLVADLQSESAPAEVPALKSR-------GQRNSL
Mb0049c|M.bovis_AF2122/97 ERVSAATKAVTLGDLQRLVADLQVESAPAQMPALKSR-------AKRTEL
Rv0048c|M.tuberculosis_H37Rv ERVSAATKAVTLGDLQRLVADLQVESAPAQMPALKSR-------AKRTEL
MAV_0069|M.avium_104 ERVSAATRAVTLGDLQTLVCDLQTGPQPPALDPSPPS-------GRVRGW
MAB_4905|M.abscessus_ATCC_1997 ERVTAATSAKTLGDLSALVTDLQLDAPPVALPREHKP----SAWRQRTPF
MLBr_00169|M.leprae_Br4923 DRLAKAYAATTYQELEQLRDDLPGSQVSARRGGNPNP-------------
TH_1268|M.thermoresistible__bu ERVDVALAARTRGELDKVLADLPMARRPDLAQS-----------------
:*: * * * :* : **
Mflv_0869|M.gilvum_PYR-GCK GVKAAIAAVLVVLGIAIGWGLYGNSS------SPLSFQTDPGAKDDGIPA
Mvan_6038|M.vanbaalenii_PYR-1 GIKAAIAGVLVVLGIAIGWGLYGNTP------SPLNFTSDPGAKADGIPA
MSMEG_6902|M.smegmatis_MC2_155 GFKIASAVVLVLLGIGIGWGMYGSSP------TPFHVASDPGAQADGIAP
MUL_0066|M.ulcerans_Agy99 GLLAAALGVSILLGVAIGWGLYGNTR------SPLDFTTDPGAKPDGVAA
MMAR_0067|M.marinum_M GLLAAALGVSILLGVAIGWGLYGNTR------SPLDFTTDPGAKPDGVAA
Mb0049c|M.bovis_AF2122/97 GLLAAAFVASVLLGVGIGWGVYGNTR------SPLDFTSDPGAKPDGIAP
Rv0048c|M.tuberculosis_H37Rv GLLAAAFVASVLLGVGIGWGVYGNTR------SPLDFTSDPGAKPDGIAP
MAV_0069|M.avium_104 GTLAAAFVVSVLLGIGIGWGLYGNTS------SPLDFTSDPGAKPDGVNA
MAB_4905|M.abscessus_ATCC_1997 LVIAAFSAAVIALGVGLLVRESGTAERPGSAGAPGAVGRGAGPIDDGVAP
MLBr_00169|M.leprae_Br4923 ------APSTLLLALMSGFERRGRWN---------------------VP-
TH_1268|M.thermoresistible__bu ------TQPLLLRGRFSTLSRKGEWS---------------------VPA
: . * :
Mflv_0869|M.gilvum_PYR-GCK RVLTPP----RQLQSLGGFTGLFEQMRQKFGSTMGYELDIHSDMAYLDRP
Mvan_6038|M.vanbaalenii_PYR-1 TVLTAP----KQLQSLGGFNGLFEQMRKKFGSTMGYELDIHSDMAFLDRP
MSMEG_6902|M.smegmatis_MC2_155 EVLAAP----RQLQSLNGFNGLFDQMRKKFGNTMGYELDIHSDMAFLDRP
MUL_0066|M.ulcerans_Agy99 VVLTPP----KQLHSLGGLTGLLEQTRKRFGDTMGYRMVIYPEYAVLDRK
MMAR_0067|M.marinum_M VVLTPP----KQLHSLGGLTGLLEQTRKRFGDTMGYRMVIYPEYAVLDRK
Mb0049c|M.bovis_AF2122/97 VVLTPP----RQLHSLGGLTGLLEQTRKRFGDTMGYRLVIYPEYASLDRV
Rv0048c|M.tuberculosis_H37Rv VVLTPP----RQLHSLGGLTGLLEQTRKRFGDTMGYRLVIYPEYASLDRV
MAV_0069|M.avium_104 VVLTPP----TQLHSVGGLTGLLEQMRKRFGSTLGYRLVIYPTYAALDRP
MAB_4905|M.abscessus_ATCC_1997 TVIPRPAPAKKNIFTAPGLSTLIDRIHQKFGDSTGYELDLYPEYAIIERA
MLBr_00169|M.leprae_Br4923 ----------RKLTTFSLWGSGVLDLRYADFTSTEVELHAYSVMGVQTIL
TH_1268|M.thermoresistible__bu RVVVDT----RMCDTTLDFTVAMLRS-----PVVHVDIDDYLSTTTLILP
: . : :
Mflv_0869|M.gilvum_PYR-GCK DPQDNRRSLTYYYRGG-WGEPSGSPTAVSADERLVDLAKFDFEKILGVVR
Mvan_6038|M.vanbaalenii_PYR-1 DPQDNRRSLSYHYRGG-WGEPTGSPSTVDADARLVDLAKFDYEKTLGILR
MSMEG_6902|M.smegmatis_MC2_155 DPSDNRREMSYTYRGG-WGDPSGSPSAVDSDARLVDLSKFDYEKTLAIMR
MUL_0066|M.ulcerans_Agy99 DPADERRILSYTYRGG-WGDPTGSARSGAD-TALVDLGKFDVKTAVGIMR
MMAR_0067|M.marinum_M DPADERRILSYTYRGG-WGDPTGSARSGAD-TALVDLGKFDVKTAVGIMR
Mb0049c|M.bovis_AF2122/97 DPADDRRVLAYTYRGG-WGDATSSAKSIAD-VSVVDLSKFDAKTAVSIMR
Rv0048c|M.tuberculosis_H37Rv DPADDRRVLAYTYRGG-WGDATSSAKSIAD-VSVVDLSKFDAKTAVGIMR
MAV_0069|M.avium_104 DPSDDRRVLAYTYRGG-WGDPTSSAKSSSDGPVLVDLSKFDVTAAVGIMR
MAB_4905|M.abscessus_ATCC_1997 DPDEPKGLISYLYREGTFDDPDRRPRSFDN---LGDVGAFDQAAILGIIR
MLBr_00169|M.leprae_Br4923 LPPEVNVEISGHGVMGSFDRQVRGQGTPGA--PTVKIRGFSLWGGVGIKR
TH_1268|M.thermoresistible__bu DGATGDVNAVETFASTVNGRVPAAPPSQRLHLVIRGRVRLATVTVRYSFG
. : :
Mflv_0869|M.gilvum_PYR-GCK GAPETVGISRADLKETWLRISPSEDPATPDAVIVEIVVN-SDFGNGRIEL
Mvan_6038|M.vanbaalenii_PYR-1 GAPETVGIARADVTDSWLRISPSEDPATPDAVIIEIIVN-SDFGTGRIEL
MSMEG_6902|M.smegmatis_MC2_155 GAPDTVGIKRADVKDTWLRIGPSEDPATPEAVNVEIFVN-SEFGNGRIEL
MUL_0066|M.ulcerans_Agy99 GAAETLGMKPKDVTNMYLSINPASDPTTPGAISLQLYVS-SDYGSGYIAF
MMAR_0067|M.marinum_M GAAETLGMKPKDVTNMYLSINPASDPTTPGAISLQLYVS-SDYGSGYIAF
Mb0049c|M.bovis_AF2122/97 GAPETLGLKQSDVKSMYLIVEPAKDPTTPAALSLSLYVS-SDYGGGYLVF
Rv0048c|M.tuberculosis_H37Rv GAPETLGLKQSDVKSMYLIVEPVKDPTTPAALSLSLYVS-SDYGGGYLVF
MAV_0069|M.avium_104 GAPETLRMKPSDVKTSYLIVEPATDPTTPGALSLSVYVS-SDYGGGYIAF
MAB_4905|M.abscessus_ATCC_1997 GAAQTLGIDRG--EPSHVIIRPN----AEGGLQINIYASRGNYESGYISV
MLBr_00169|M.leprae_Br4923 KARRPRR-------------------------------------------
TH_1268|M.thermoresistible__bu AAWRRFTGRSEP--------------------------------------
*
Mflv_0869|M.gilvum_PYR-GCK YPDGTPLAIWPANR
Mvan_6038|M.vanbaalenii_PYR-1 YPDGSTLAIWPANR
MSMEG_6902|M.smegmatis_MC2_155 YPDGTTKAIWPAGR
MUL_0066|M.ulcerans_Agy99 AGDSTIKQVNYPS-
MMAR_0067|M.marinum_M AGDGTIKQVNYPS-
Mb0049c|M.bovis_AF2122/97 AGDGTIKHVSYPS-
Rv0048c|M.tuberculosis_H37Rv AGDGTIKHVSYPS-
MAV_0069|M.avium_104 TGDGTVKQMNLPT-
MAB_4905|M.abscessus_ATCC_1997 DAQGLNPKLYPPS-
MLBr_00169|M.leprae_Br4923 --------------
TH_1268|M.thermoresistible__bu --------------