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AKWLGAPLARGVSTATRAKDSDRQDACRILDDALRDGELSMEEHRERVSAATKAVTLGDLQRLVADLQVE SAPAQMPALKSRAKRTELGLLAAAFVASVLLGVGIGWGVYGNTRSPLDFTSDPGAKPDGIAPVVLTPPRQ LHSLGGLTGLLEQTRKRFGDTMGYRLVIYPEYASLDRVDPADDRRVLAYTYRGGWGDATSSAKSIADVSV VDLSKFDAKTAVGIMRGAPETLGLKQSDVKSMYLIVEPVKDPTTPAALSLSLYVSSDYGGGYLVFAGDGT IKHVSYPS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0048c | - | - | 100% (289) | POSSIBLE MEMBRANE PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0049c | - | 1e-162 | 99.31% (289) | hypothetical protein Mb0049c |
| M. gilvum PYR-GCK | Mflv_0869 | - | 2e-75 | 51.42% (282) | hypothetical protein Mflv_0869 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4904 | - | 4e-48 | 40.22% (271) | hypothetical protein MAB_4904 |
| M. marinum M | MMAR_0067 | - | 1e-131 | 77.85% (289) | hypothetical protein MMAR_0067 |
| M. avium 104 | MAV_0069 | - | 1e-115 | 71.43% (294) | hypothetical protein MAV_0069 |
| M. smegmatis MC2 155 | MSMEG_6902 | - | 2e-80 | 52.33% (279) | hypothetical protein MSMEG_6902 |
| M. thermoresistible (build 8) | TH_1268 | - | 4e-06 | 38.60% (57) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0066 | - | 1e-131 | 77.51% (289) | hypothetical protein MUL_0066 |
| M. vanbaalenii PYR-1 | Mvan_6038 | - | 5e-75 | 51.81% (276) | hypothetical protein Mvan_6038 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0048c|M.tuberculosis_H37Rv MAKWLGAPLAR----GVSTATRAKDSDRQDACRILDDALRDGELSMEEHR
Mb0049c|M.bovis_AF2122/97 MAKWLGAPLAR----GVSTATRAKDSDRQDACRILDDALRDGELSMEEHR
MMAR_0067|M.marinum_M MAKWLGASLAR----GGSAATRAKDTDRQDACQILDSALSDGQLSMEEHR
MUL_0066|M.ulcerans_Agy99 MAKWLGASLAR----GGSAATRAKDTDRQDACQILDSALSDGQLSMEEHR
MAV_0069|M.avium_104 MAKWLGTPPAGTAPPSGRASTRAKDSDRQSTCTILDNALNDGELSAEEHR
Mflv_0869|M.gilvum_PYR-GCK MASGGSGRRTSSG--RRTAWTRAKDSDRNETCQILDTALADGQLSMTEHG
Mvan_6038|M.vanbaalenii_PYR-1 MASGSSGRRTSS--------TRAKDSDRNETCQLLDAALAEGQLSMTEHG
MSMEG_6902|M.smegmatis_MC2_155 MAT----RQTSM--------TRAKDSDRNDTCKVLDSAMAEGQLSMEEHR
MAB_4904|M.abscessus_ATCC_1997 ------------------MATRAKDSDREATCKALDTAFGDGQISTEEHR
TH_1268|M.thermoresistible__bu --------MDSG---HHDAHLRASDADRAAVRQLLERAVGEGMLTLDEYT
**.*:** . *: *. :* :: *:
Rv0048c|M.tuberculosis_H37Rv ERVSAATKAVTLGDLQRLVADLQVESAPAQMPALKSR-------AKRTEL
Mb0049c|M.bovis_AF2122/97 ERVSAATKAVTLGDLQRLVADLQVESAPAQMPALKSR-------AKRTEL
MMAR_0067|M.marinum_M QRVATATQAVTLGDLQHLVADLQSESAPAEVPALKSR-------GQRNSL
MUL_0066|M.ulcerans_Agy99 QRVATATQAVTLGDLQQLVADLQSESAPAEVPALKSR-------GQRNSL
MAV_0069|M.avium_104 ERVSAATRAVTLGDLQTLVCDLQTGPQPPALDPSPPS-------GRVRGW
Mflv_0869|M.gilvum_PYR-GCK ERVKSATTASTLGQLQDLVSDLQTAKTI-AEPTVITRVINRQVA--RPGW
Mvan_6038|M.vanbaalenii_PYR-1 ERVKAATTAATLGQLQDLVSDLQTARSLNVDVPVITKVINRRIPGVQAGW
MSMEG_6902|M.smegmatis_MC2_155 DRLSAAMKATTLGELADLVADLQNEAAPVRLPTLKPPRIPRPSSG-SPGW
MAB_4904|M.abscessus_ATCC_1997 QRIALATRAQTLGELKGVVADLQITAHAAETPTAPPP---------RRRW
TH_1268|M.thermoresistible__bu ERVDVALAARTRGELDKVLADLPMARRPDLAQSTQPL-------------
:*: * * * *:* ::.** . .
Rv0048c|M.tuberculosis_H37Rv GLLAAAFVASVLLGVGIGWGVYGNTRSPLDFTSDPGAKPDGIAPVVLTPP
Mb0049c|M.bovis_AF2122/97 GLLAAAFVASVLLGVGIGWGVYGNTRSPLDFTSDPGAKPDGIAPVVLTPP
MMAR_0067|M.marinum_M GLLAAALGVSILLGVAIGWGLYGNTRSPLDFTTDPGAKPDGVAAVVLTPP
MUL_0066|M.ulcerans_Agy99 GLLAAALGVSILLGVAIGWGLYGNTRSPLDFTTDPGAKPDGVAAVVLTPP
MAV_0069|M.avium_104 GTLAAAFVVSVLLGIGIGWGLYGNTSSPLDFTSDPGAKPDGVNAVVLTPP
Mflv_0869|M.gilvum_PYR-GCK GVKAAIAAVLVVLGIAIGWGLYGNSSSPLSFQTDPGAKDDGIPARVLTPP
Mvan_6038|M.vanbaalenii_PYR-1 GIKAAIAGVLVVLGIAIGWGLYGNTPSPLNFTSDPGAKADGIPATVLTAP
MSMEG_6902|M.smegmatis_MC2_155 GFKIASAVVLVLLGIGIGWGMYGSSPTPFHVASDPGAQADGIAPEVLAAP
MAB_4904|M.abscessus_ATCC_1997 PALAATAVVAAAIGAGA--GIYATRPS----APDPGAVSDGIAPVVIAPA
TH_1268|M.thermoresistible__bu -------------------LLRG------RFSTLSRKGEWSVPARVVVDT
: . . . .: . *:. .
Rv0048c|M.tuberculosis_H37Rv RQLHSLGGLTGLLEQTRKRFGDTMGYRLVIYPEYASLDRVDPADDRRVLA
Mb0049c|M.bovis_AF2122/97 RQLHSLGGLTGLLEQTRKRFGDTMGYRLVIYPEYASLDRVDPADDRRVLA
MMAR_0067|M.marinum_M KQLHSLGGLTGLLEQTRKRFGDTMGYRMVIYPEYAVLDRKDPADERRILS
MUL_0066|M.ulcerans_Agy99 KQLHSLGGLTGLLEQTRKRFGDTMGYRMVIYPEYAVLDRKDPADERRILS
MAV_0069|M.avium_104 TQLHSVGGLTGLLEQMRKRFGSTLGYRLVIYPTYAALDRPDPSDDRRVLA
Mflv_0869|M.gilvum_PYR-GCK RQLQSLGGFTGLFEQMRQKFGSTMGYELDIHSDMAYLDRPDPQDNRRSLT
Mvan_6038|M.vanbaalenii_PYR-1 KQLQSLGGFNGLFEQMRKKFGSTMGYELDIHSDMAFLDRPDPQDNRRSLS
MSMEG_6902|M.smegmatis_MC2_155 RQLQSLNGFNGLFDQMRKKFGNTMGYELDIHSDMAFLDRPDPSDNRREMS
MAB_4904|M.abscessus_ATCC_1997 K-LFSVPGLTGLLAQMRAKFGDTVGIELTIRATNASLVRIEASDPDLPIT
TH_1268|M.thermoresistible__bu RMCDTTLDFT--VAMLRS---PVVHVDIDDYLSTTTLILPDGATGDVNAV
: .:. . * .: : : * :
Rv0048c|M.tuberculosis_H37Rv YTYRGGWGDATSSAKSIAD-VSVVDLSKFDAKTAVGIMRGAPETLGLKQS
Mb0049c|M.bovis_AF2122/97 YTYRGGWGDATSSAKSIAD-VSVVDLSKFDAKTAVSIMRGAPETLGLKQS
MMAR_0067|M.marinum_M YTYRGGWGDPTGSARSGAD-TALVDLGKFDVKTAVGIMRGAAETLGMKPK
MUL_0066|M.ulcerans_Agy99 YTYRGGWGDPTGSARSGAD-TALVDLGKFDVKTAVGIMRGAAETLGMKPK
MAV_0069|M.avium_104 YTYRGGWGDPTSSAKSSSDGPVLVDLSKFDVTAAVGIMRGAPETLRMKPS
Mflv_0869|M.gilvum_PYR-GCK YYYRGGWGEPSGSPTAVSADERLVDLAKFDFEKILGVVRGAPETVGISRA
Mvan_6038|M.vanbaalenii_PYR-1 YHYRGGWGEPTGSPSTVDADARLVDLAKFDYEKTLGILRGAPETVGIARA
MSMEG_6902|M.smegmatis_MC2_155 YTYRGGWGDPSGSPSAVDSDARLVDLSKFDYEKTLAIMRGAPDTVGIKRA
MAB_4904|M.abscessus_ATCC_1997 YPYQGGFRDGGAMPGTWRN-VKIGDLSRFDPTKIVGVLRGAPETLNVPTA
TH_1268|M.thermoresistible__bu ETFAS---------------------------TVNGRVPAAPPSQRLHLV
: . . : .*. : :
Rv0048c|M.tuberculosis_H37Rv DVKSMYLIVEPVKDPTTPAALSLSLYVSSDYGGGYLVFAGDGTIKHVSYP
Mb0049c|M.bovis_AF2122/97 DVKSMYLIVEPAKDPTTPAALSLSLYVSSDYGGGYLVFAGDGTIKHVSYP
MMAR_0067|M.marinum_M DVTNMYLSINPASDPTTPGAISLQLYVSSDYGSGYIAFAGDGTIKQVNYP
MUL_0066|M.ulcerans_Agy99 DVTNMYLSINPASDPTTPGAISLQLYVSSDYGSGYIAFAGDSTIKQVNYP
MAV_0069|M.avium_104 DVKTSYLIVEPATDPTTPGALSLSVYVSSDYGGGYIAFTGDGTVKQMNLP
Mflv_0869|M.gilvum_PYR-GCK DLKETWLRISPSEDPATPDAVIVEIVVNSDFGNGRIELYPDGTPLAIWPA
Mvan_6038|M.vanbaalenii_PYR-1 DVTDSWLRISPSEDPATPDAVIIEIIVNSDFGTGRIELYPDGSTLAIWPA
MSMEG_6902|M.smegmatis_MC2_155 DVKDTWLRIGPSEDPATPEAVNVEIFVNSEFGNGRIELYPDGTTKAIWPA
MAB_4904|M.abscessus_ATCC_1997 GDGGTVMVIKPSDD-----GVDITITVSDKDRTGRMLVAGNGEPKEVTPA
TH_1268|M.thermoresistible__bu IRGRVRLAT---------------VTVRYSFGAAWRRFTGRSEP------
: : * . . . .
Rv0048c|M.tuberculosis_H37Rv S-
Mb0049c|M.bovis_AF2122/97 S-
MMAR_0067|M.marinum_M S-
MUL_0066|M.ulcerans_Agy99 S-
MAV_0069|M.avium_104 T-
Mflv_0869|M.gilvum_PYR-GCK NR
Mvan_6038|M.vanbaalenii_PYR-1 NR
MSMEG_6902|M.smegmatis_MC2_155 GR
MAB_4904|M.abscessus_ATCC_1997 S-
TH_1268|M.thermoresistible__bu --