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PEPEPVRDDLTELQRRRALTEDAARPDAVQRRHDAGGRTARENVADLVDPGSFVEYGRFAVAPQRMRRDV EDLIARTPADGLIAGTARINGDACAVLSYDYTVLAGTQGGLGHRKKDRLFELIERMALPTVFFAEGGGGR PVDTDYPVVSALDTRAFALWAKLSGQVPRIAVVKGRCFAGNAVIAGASDLIVATRDASLGMGGPAMIAGG GLGAVAPDDVGPMSVQEPNGNVDVVVDDEAAAVAVAKRLIGYFQGCVSQWSAPDQTPLRTAVPERARRAY DVAPVIETLADEDSVTFLRPRFAREMVTALARIEGRPVGVIANDTRFTAGAITAAASDKAARFLQLCDAF GLPVVSLIDCPGYMVGPAAEAESLVRRASRMLVAGAALRVPLIAVILRRGYGLGAQAMAGGSLHEPLLTV AWPGAHLGPMGLEGAVRLGMRKELEAIADEAEREARVVAATAAAQEYAKALNAAMLFEIDDVIDPAETRA VIAATLVAADSGTKKPAPDRSRFIDTW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0781 | - | - | 100% (518) | propionyl-CoA carboxylase |
| M. gilvum PYR-GCK | Mflv_4327 | - | 1e-58 | 31.96% (510) | propionyl-CoA carboxylase |
| M. gilvum PYR-GCK | Mflv_1170 | - | 6e-57 | 31.16% (507) | carboxyl transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3829c | accD4 | 8e-57 | 31.61% (503) | propionyl-CoA carboxylase beta chain |
| M. tuberculosis H37Rv | Rv3799c | accD4 | 8e-57 | 31.61% (503) | propionyl-CoA carboxylase beta chain |
| M. leprae Br4923 | MLBr_00102 | accD4 | 2e-54 | 30.91% (508) | putative acyl CoA carboxylase beta subunit |
| M. abscessus ATCC 19977 | MAB_4676 | - | 0.0 | 77.16% (521) | putative carboxyl transferase/pyruvate carboxylase |
| M. marinum M | MMAR_1951 | accA3_1 | 1e-149 | 56.80% (493) | bifunctional protein acetyl-/propionyl-coenzyme A |
| M. avium 104 | MAV_3657 | - | 1e-153 | 57.40% (493) | carbamoyl-phosphate synthase/carboxyl transferase |
| M. smegmatis MC2 155 | MSMEG_6577 | - | 0.0 | 77.63% (514) | methylmalonyl-CoA carboxyltransferase 12S subunit |
| M. thermoresistible (build 8) | TH_2343 | - | 0.0 | 80.66% (512) | methylmalonyl-CoA carboxyltransferase 12S subunit |
| M. ulcerans Agy99 | MUL_3864 | accD4_2 | 2e-60 | 31.94% (501) | propionyl-CoA carboxylase beta chain 4 AccD4_2 |
| M. vanbaalenii PYR-1 | Mvan_0066 | - | 0.0 | 88.42% (518) | propionyl-CoA carboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M --MTLLIANRGEIALRIIRTANELGIATVAVYAEDDAETPHVHAADEAIG
MAV_3657|M.avium_104 MTASLLVANRGEIALRIIRTATELGMRTVAVYAADDAHSPHVHAADEAMP
Mb3829c|M.bovis_AF2122/97 --------------------------------------------------
Rv3799c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00102|M.leprae_Br4923 --------------------------------------------------
MUL_3864|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M LPGKGASAYLDRAAILAAAAKAGARLIHPGYGFLSENSEFVWACTAAGYT
MAV_3657|M.avium_104 LPGSGPPAYLNQAALLAVAENTGATLIHPGYGFLSENAEFAEACAAARRT
Mb3829c|M.bovis_AF2122/97 --------------------------------------------------
Rv3799c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00102|M.leprae_Br4923 --------------------------------------------------
MUL_3864|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M FVGPDADVLDLVGNKASARGVATAAGVPVLAATEGPSSVEDVRAFFADQD
MAV_3657|M.avium_104 FVGPDARVLELLGNKTAARRAAIAAEVPTLAATDGPSGVEDIEAFFAAHP
Mb3829c|M.bovis_AF2122/97 --------------------------------------------------
Rv3799c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00102|M.leprae_Br4923 --------------------------------------------------
MUL_3864|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M GGIMIKALAGGGGRGMRKVECGDQIDNAYRQCAAEAQLGFGNPALFAEAL
MAV_3657|M.avium_104 GGIMIKALAGGGGRGMRKVHNAAQIAGAYQRCAAEARLGFGDPALFAEAL
Mb3829c|M.bovis_AF2122/97 --------------------------------------------------
Rv3799c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00102|M.leprae_Br4923 --------------------------------------------------
MUL_3864|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M LHNARHIEVQVVAAPVGHQTRALALGDRDCSIQRRYQKLVEIAPAQQLSD
MAV_3657|M.avium_104 LGDARHIEVQVVAAPAGHQTHALAVGDRDCSIQRRYQKLIEIAPAQGLSE
Mb3829c|M.bovis_AF2122/97 --------------------------------------------------
Rv3799c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00102|M.leprae_Br4923 --------------------------------------------------
MUL_3864|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M LLRRQLHQAAARLCARVGLRGVATVEFLVAGDKFVFLEINPRIQVEHTIT
MAV_3657|M.avium_104 ELRRALHQAAVRLCARVGLRGLATVEFLVSGERFVFLEVNPRIQVEHTVT
Mb3829c|M.bovis_AF2122/97 --------------------------------------------------
Rv3799c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00102|M.leprae_Br4923 --------------------------------------------------
MUL_3864|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M EEVTGVDLVAAQLAIAGGASYYELGHQLGLPAGIASDGSEVIGEPAVRRG
MAV_3657|M.avium_104 EQTTGLDLVAVQLAIAGGESYYRLG----LPAGIASDGTEVIGEPAAQRG
Mb3829c|M.bovis_AF2122/97 --------------------------------------------------
Rv3799c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00102|M.leprae_Br4923 --------------------------------------------------
MUL_3864|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M IAIQTRINMETLAADGSVSPATGTLNVFSPPSGPGVRVDTYGRPGLVPSP
MAV_3657|M.avium_104 IAIQLRVNAETFGADFSVLPSAGTLTAFCPPSGRGVRVDTYGRPGLVVSP
Mb3829c|M.bovis_AF2122/97 --------------------------------------------------
Rv3799c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00102|M.leprae_Br4923 --------------------------------------------------
MUL_3864|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M LYDSLLAKVITHVHGSSFPAALRKARTVLSDFSIEGIATNAGLLREVLSD
MAV_3657|M.avium_104 QYDSLLAKVIVAVHGSSWRAAMRKADTALSEFGVEGVATNIGFLRRLLAE
Mb3829c|M.bovis_AF2122/97 --------------------------------------------------
Rv3799c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00102|M.leprae_Br4923 --------------------------------------------------
MUL_3864|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M ERLVSGVVPTTFLDEILPALVEAAQSQQREVRVVALELYPGEQALRAQMA
MAV_3657|M.avium_104 QRLETGWVNTDFVDDKLPELAAAALTHQPGPQPGAVELYPGEDALRAQLA
Mb3829c|M.bovis_AF2122/97 --------------------------------------------------
Rv3799c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00102|M.leprae_Br4923 --------------------------------------------------
MUL_3864|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M GTVVEVPPEGVDIGAGDQLVVLEAMKMQHVLAAPHRLHTVRILVTPGQVV
MAV_3657|M.avium_104 GTVVEVAPEGADYPAGAQLVVLEAMKMQHVLAAPDALRTVRVLVTPGQVV
Mb3829c|M.bovis_AF2122/97 --------------------------------------------------
Rv3799c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00102|M.leprae_Br4923 --------------------------------------------------
MUL_3864|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK -----------------------MPEPEPVRDDLTELQRRRALTEDAARP
Mvan_0066|M.vanbaalenii_PYR-1 -------------------------MPDPIRDDLAELWRRRALTEDAARP
TH_2343|M.thermoresistible__bu -----------------------------MRPELAELLGRRRLTTDAARP
MAB_4676|M.abscessus_ATCC_1997 ------------------------MADEQLREDHVELLARRALTEDAARP
MSMEG_6577|M.smegmatis_MC2_155 ------------------------MTDEDLRDDLAEVLRRRALTQDDARP
MMAR_1951|M.marinum_M ATGDPLVVFCRTDAGEDVESSLAAVDLDRSRADLEEVRARHRLTLDEGRE
MAV_3657|M.avium_104 GTGDPLLVFTRTTGGDDGESETAATDLDLTRADLDEVIERHARTLDEGRP
Mb3829c|M.bovis_AF2122/97 -------------------MTVTEPVLHTTAEKLAELRERLELAKEPGGE
Rv3799c|M.tuberculosis_H37Rv -------------------MTVTEPVLHTTAEKLAELRERLELAKEPGGE
MLBr_00102|M.leprae_Br4923 ------------------------MIMKSTAEKLAELRVRLELANEPGGE
MUL_3864|M.ulcerans_Agy99 -----------------------MTKAQDWDETLDDLDRRRGRARSMGGP
:: * : . .
Mflv_0781|M.gilvum_PYR-GCK DAVQRRHDAGGRTARENVADLVDPGSFVEYGRFAVAPQRMRRDVEDLIAR
Mvan_0066|M.vanbaalenii_PYR-1 DAVERRHAAGGRTARENVADLVDTGSFVEYGRFAIAPQRMRRDVEDLITR
TH_2343|M.thermoresistible__bu EAVQRRHGAGGRTARENIEDLVDPGSFVEYGRFVVAAQRQRRDLADLIAR
MAB_4676|M.abscessus_ATCC_1997 DAVARRHAAGGRTARENISDLVDAGSFVEYGRFAIAAQRRRRELADLIAR
MSMEG_6577|M.smegmatis_MC2_155 DAVERRRASGARTARQNIADLVDDGSFVEYGRFAIAAQRQRRSLDDLIAR
MMAR_1951|M.marinum_M LAVGKRHKQGRRTARENIADLVDAGSFVEYGALAIAAQRSRRSEEDLIVS
MAV_3657|M.avium_104 DAVAKRHRQGRRTARENIDDLVDPGSFVEYGALAIAAQRSRRSEEDLIAN
Mb3829c|M.bovis_AF2122/97 KAAAKRDKKGIPSARARIYELVDPGSFMEIGALCRTPGDPN--------A
Rv3799c|M.tuberculosis_H37Rv KAAAKRDKKGIPSARARIYELVDPGSFMEIGALCRTPGDPN--------A
MLBr_00102|M.leprae_Br4923 KAAAKRDKKNIPSARARIYALVDPGTFLEIGALTRTPGDPN--------A
MUL_3864|M.ulcerans_Agy99 ERLDRHHGQGKLDARARVQRLLDPGTFRELGTLVGG-------------E
:: . ** .: *:* *:* * * :
Mflv_0781|M.gilvum_PYR-GCK TPADGLIAGTARING-------DACAVLSYDYTVLAGTQGGLGHRKKDRL
Mvan_0066|M.vanbaalenii_PYR-1 TPADGLVAGTARVDG-------HPCAVLSYDYTVLAGTQGALGHRKKDRL
TH_2343|M.thermoresistible__bu TPADGLVAGTARING-------RPAAVLSYDYTVLAGTQGVFGHFKKDRL
MAB_4676|M.abscessus_ATCC_1997 TPADGLVAGTARVNGNLFGADRSACAVLSYDYTVLAGTQGALGHHKKDRL
MSMEG_6577|M.smegmatis_MC2_155 TPADGLVAGTARVDG-------QPCAVLSYDYTVLAGTQGALGHLKKDRL
MMAR_1951|M.marinum_M TPADGLVAGLATIGADRFGNNAAEAVVVSYDYTVLAGTQGMRNHAKTDRV
MAV_3657|M.avium_104 TPADGLVAGLATVGADRFGRAAAQAVVASYDYTVLAGTQGMRNHAKTDRV
Mb3829c|M.bovis_AF2122/97 LYGDGVVTGHGLING-------RPVGVFSHDQTVFGGTVGEMFGRKVARL
Rv3799c|M.tuberculosis_H37Rv LYGDGVVTGHGLING-------RPVGVFSHDQTVFGGTVGEMFGRKVARL
MLBr_00102|M.leprae_Br4923 LYGDGVVTGHGLING-------RQVGVFSHDQTVFGGTVGEMFGRKVARL
MUL_3864|M.ulcerans_Agy99 IAADAIITGAGQING-------VPVLVGAEDFTTLAGTIAPGSNSKRYRI
.*.:::* . :.. * : * *.:.** . * *:
Mflv_0781|M.gilvum_PYR-GCK FELIERMALPTVFFAEGGGGRPVDTDYPVVSALDTRAFALWAKLSGQVPR
Mvan_0066|M.vanbaalenii_PYR-1 FELIERMQLPTVFFAEGGGGRPGDTDYPVVSALDTRAFALWARLSGVVPR
TH_2343|M.thermoresistible__bu FDLIERMRLPTVFFAEGGGGRPGDTDHPTVSSLQVRAFKLWAGLSGLVPR
MAB_4676|M.abscessus_ATCC_1997 FDLIERMKLPTVFFAEGGGGRPGDTDYPVVSMLDVRAFKLWAALSGVVPR
MSMEG_6577|M.smegmatis_MC2_155 FDLIERMRLPTVFFAEGGGGRPGDTDIPTVSSLDVRAFKLWAALSGLVPR
MMAR_1951|M.marinum_M FGLAARKRIPVVLFAEGGGGRPGDTDLGNISGLDVPTFRMLAGLSGRVPL
MAV_3657|M.avium_104 FDLAARKRLPVVLFAEGGGGRPGDTDVGGAAGLDVPTFRMLAGLRGRVPL
Mb3829c|M.bovis_AF2122/97 MEWCAMVGCPIVGINDSGGARIQDAVTS--LAWYAELGRRHELLSGLVPQ
Rv3799c|M.tuberculosis_H37Rv MEWCAMVGCPIVGINDSGGARIQDAVTS--LAWYAELGRRHELLSGLVPQ
MLBr_00102|M.leprae_Br4923 MEWCAMAGCPIVGINDSGGARIQDAVTS--LAWYAELGRRHELLSGIVPQ
MUL_3864|M.ulcerans_Agy99 AELAVRDKIPLVMLLEGAGFRPTGVHYG--RTPTDLLAQ--ARCSGRVPT
* * : :..* * .. * **
Mflv_0781|M.gilvum_PYR-GCK IAVVKGRCFAGNAVIAGASDLIVATRDASLGMG-GPAMIAGGGLGAVAPD
Mvan_0066|M.vanbaalenii_PYR-1 IAIVKGRCFAGNAVIAGASDLIVATRDASLGMG-GPAMIAGGGLGDVPPD
TH_2343|M.thermoresistible__bu IAVVKGRCFAGNAVIAGAADLIVATADTSIGMG-GPAMIAGGGLGDVHPD
MAB_4676|M.abscessus_ATCC_1997 ISVVNGRCFAGNAVIAGCSDLIVATKDTSIGMG-GPAMIAGGGLGEVHPD
MSMEG_6577|M.smegmatis_MC2_155 IAVVRGRCFAGNAVIAGAADLIVATEDASIGMG-GPAMIAGGGLGEVAPE
MMAR_1951|M.marinum_M VSIVSGRCFAGNAALAGVCDVIIATPDANIGMG-GPAMIEGGGLGVYPPE
MAV_3657|M.avium_104 VSVVSGRCFAGNAALAGVCDVIIATPDANIGMG-GPAMIEGGGLGVYPPE
Mb3829c|M.bovis_AF2122/97 ISIILGKCAGGAVYSPIQTDLVVAVRDQGYMFVTGPDVIKDVTGEDVSLD
Rv3799c|M.tuberculosis_H37Rv ISIILGKCAGGAVYSPIQTDLVVAVRDQGYMFVTGPDVIKDVTGEDVSLD
MLBr_00102|M.leprae_Br4923 ISIVLGKCAGGAVYSPIQTDLVVAVRGQGYMFVTGPDVIKDVTGEEVSLD
MUL_3864|M.ulcerans_Agy99 ITAVLGPSAGHGAPVAPMCDFTVMTR-QGAIFTAGPPVVKESTGEDISKE
:: : * . . . . *. : . . : ** :: :
Mflv_0781|M.gilvum_PYR-GCK DVGPMSVQEPNGNVDVVVDDEAAAVAVAKRLIGYFQG-----------CV
Mvan_0066|M.vanbaalenii_PYR-1 EVGPMTTQEPNGNVDVVVDDEAEAVAVTKTLLGYFQG-----------PA
TH_2343|M.thermoresistible__bu EVGPISVQEPNGVVDLVVADETEAVAAARRLLGYFQG-----------ST
MAB_4676|M.abscessus_ATCC_1997 EVGPIAVQSTNGVVDVVVDDEEQAVTVAKRLISYFQG-----------AV
MSMEG_6577|M.smegmatis_MC2_155 DVGPISVQAPNGVVDIVVADEPEAVAVTKTLLGYFGG-----------PV
MMAR_1951|M.marinum_M AIGPIDVQRRNGVVSLVARDEAHAVSLAKRYLGYFQG-----------KV
MAV_3657|M.avium_104 AIGPIAVQRRNGVVGLVARDEAHAVSLAKQYLSYFQG-----------RL
Mb3829c|M.bovis_AF2122/97 ELGGADHQASYGNIHQVVESEAAAYQYVRDFLSFLPSNCFDKPPVVNPGL
Rv3799c|M.tuberculosis_H37Rv ELGGADHQASYGNIHQVVESEAAAYQYVRDFLSFLPSNCFDKPPVVNPGL
MLBr_00102|M.leprae_Br4923 ELGGVDSQAKYGNIHQVVESEAAAFGYVRDFLSFLPPNCFDKAPIVNPGL
MUL_3864|M.ulcerans_Agy99 DLGGPDIALASGVIHNVADDDAAALDMIRRSLSYFPPSAWSYPPSL-PAS
:* * : *. .: * : :.::
Mflv_0781|M.gilvum_PYR-GCK SQWSAPDQTPLRTAVPERARRAYDVAPVIETLADEDSVTFLRPRFAREMV
Mvan_0066|M.vanbaalenii_PYR-1 DSWSAPDQTVLRTAVPDRARRAYDVAPVIETIADEDSVTFLRPRFAREMV
TH_2343|M.thermoresistible__bu APGEVADQTVLRTMVPERARRAYDVTPVIETLADADSVTVLRPRFAREMV
MAB_4676|M.abscessus_ATCC_1997 APGDGADQTALRTMIPERARRAYPIRPIIETLADTGSVTFLREKFAPEMA
MSMEG_6577|M.smegmatis_MC2_155 DAGPERDQTPLRTMVPERARRAYPVGPVIETLADEGSVTYLREKFAPEMV
MMAR_1951|M.marinum_M EGWQAPDPRLARQVVPENRLRAYDVHRAIESIVDVGSVLELRADYGVGIV
MAV_3657|M.avium_104 DRWQAPDPRVARHVVPQNRLRAYDVHRAIEAIVDVGSVLELRPDYGVGIV
Mb3829c|M.bovis_AF2122/97 EPEITGHDLELDSIVPDSDNMAYDMHEVLLRIFDDGDFLDVAAQAGQAII
Rv3799c|M.tuberculosis_H37Rv EPEITGHDLELDSIVPDSDNMAYDMHEVLLRIFDDGDFLDVAAQAGQAII
MLBr_00102|M.leprae_Br4923 EPEIMAHDLELDSIVPDSDNTAYDMREVLLRIFDDGHFLDVAAQAGQAII
MUL_3864|M.ulcerans_Agy99 GTTARRSTPELLDIVSRDNRRVYDMRAVLDVVFDSTEWFEVQPQFGKAII
:. .* : : : * : . :
Mflv_0781|M.gilvum_PYR-GCK TALARIEGRPVGVIANDTRFTAGAITAAASDKAARFLQLCDAFGLPVVSL
Mvan_0066|M.vanbaalenii_PYR-1 TALARVEGRPVGVIANDTRFTAGAITAAASDKAARFLQLCDAFGFPVVSL
TH_2343|M.thermoresistible__bu TALARIDGRPVGVLANDTRYMAGAITAAASDKAARFLQLCDVFGLPVISL
MAB_4676|M.abscessus_ATCC_1997 TALARIEGRPIGVLANNSMVMAGAITAAASDKAARFLQLCDAFGLPVLSL
MSMEG_6577|M.smegmatis_MC2_155 TAFARMAGRPVGILANNTMVMAGAITATASDKAARFLQLCDAFGIPVVSL
MMAR_1951|M.marinum_M TALVRIEGFAYGLIANSSHHLGGAIDAEASDKVTDFLMLCESFRLPVISL
MAV_3657|M.avium_104 TALVRVEGVPCGLIANSTHHLGGAIDAEAADKAGDFLALCESFGLPVISL
Mb3829c|M.bovis_AF2122/97 TGYARVDGRTVGVVANQPMHMSGAIDNEASDKAARFIRFSDAFDIPLVFV
Rv3799c|M.tuberculosis_H37Rv TGYARVDGRTVGVVANQPMHMSGAIDNEASDKAARFIRFSDAFDIPLVFV
MLBr_00102|M.leprae_Br4923 TGYARVDGRTVGVVANQPMHLSGAIDNEASDKAARFIRFCDAFNIPLVFV
MUL_3864|M.ulcerans_Agy99 CALAHLGGHPVAVVANQPRVLAGSIDADAADKAAHFIMVADSFHLPIVFL
. .:: * . .::**.. .*:* *:**. *: ..: * :*:: :
Mflv_0781|M.gilvum_PYR-GCK IDCPGYMVGPAAEAESLVRRASRMLVAGAALRVPLIAVILRRGYGLGAQA
Mvan_0066|M.vanbaalenii_PYR-1 IDCPGYMVGPAAEAESLVRRASRMLVAGAALCVPMVAVILRRGYGLGAQA
TH_2343|M.thermoresistible__bu IDCPGYMVGPAAEAEALVRRGSRLLVAGAALRVPLIAVVLRRGYGLGAQA
MAB_4676|M.abscessus_ATCC_1997 VDCPGYMVGPAAEAEALVRRASRMLVAGAALRVPLVSVILRRGYGLGAQA
MSMEG_6577|M.smegmatis_MC2_155 VDCPGYMVGPAAEAEALVRRGSRLLVAGAALTVPLIAVILRRGYGLGAQA
MMAR_1951|M.marinum_M CDTPGFMVGPDAETQASVRRFGRMFLAGARLTVPLGMIILRKGYGLGAMA
MAV_3657|M.avium_104 CDTPGFMVGPDAETQAAVRRFGRMFVLGARLTVPLGMIILRKGYGLGAMA
Mb3829c|M.bovis_AF2122/97 VDTPGFLPGVEQEKNGIIKRGGRFLYAVVEADVPKVTITIRKSYGG-AYA
Rv3799c|M.tuberculosis_H37Rv VDTPGFLPGVEQEKNGIIKRGGRFLYAVVEADVPKVTITIRKSYGG-AYA
MLBr_00102|M.leprae_Br4923 VDTPGFLPGVEQEKNGIIKRGGRFLYAVVEADVPKVTITIRKSYGG-AYA
MUL_3864|M.ulcerans_Agy99 ADNPGMLPGSRSERAGVLRSGARMFAAQTAATTLKLHVTLRKAYGF-GSM
* ** : * * . :: .*:: . . : :*:.** .
Mflv_0781|M.gilvum_PYR-GCK MAGGSLHEPLLTVAWPGAHLGPMGLEGAVRLGMRKELEAIADEAEREARV
Mvan_0066|M.vanbaalenii_PYR-1 MAGGSLHEPVLTVAWPGAHLGPMGLEGAVRLGMRKELDAIEDEQEREERV
TH_2343|M.thermoresistible__bu MAGGGLHEPVLTVAWPGAHLGPMGLEGAVRLGMRKELEAIADEAEREERV
MAB_4676|M.abscessus_ATCC_1997 MTGGSLHEPLLTVAWPNAHLGPMGLEGAVRLGLRKELEAIADESAREEAV
MSMEG_6577|M.smegmatis_MC2_155 MCGGSLHEPLLTVAWPGAHLGPMGLEGAVRLGMRKELEAIENEGAREEAV
MMAR_1951|M.marinum_M MAGGSFHAPEFTIAWPTGEIGGMGLEGAVRLGFSKELAAAADDIERQELF
MAV_3657|M.avium_104 MAGGSFRAPQFTVAWPTGEIGGMGLEGAVRLGYRKELAAVTDPAERQNLF
Mb3829c|M.bovis_AF2122/97 VMGSKQLTADLNFAWPTARIAVIGADGAAQLLMKRFPDPNAPEA-QAIRK
Rv3799c|M.tuberculosis_H37Rv VMGSKQLTADLNFAWPTARIAVIGADGAAQLLMKRFPDPNAPEA-QAIRK
MLBr_00102|M.leprae_Br4923 VMGSKQLAADLNFAWPTARIAVIGADGAAQLLMKRFPDPSSPDV-QAIRK
MUL_3864|M.ulcerans_Agy99 VMG--LISFDGQVATFAYPGATMGPMGAAALSRASHADEDLS--------
: * .* . :* **. *
Mflv_0781|M.gilvum_PYR-GCK VAATAAAQEYAKALNAAMLFEIDDVIDPAETRAVIAATLVAADSGTKKPA
Mvan_0066|M.vanbaalenii_PYR-1 RLATAAAQENAKALNAAMLFEIDDVIDPAETRAVIAATFAAADTDTRKPA
TH_2343|M.thermoresistible__bu RQATAAAQRHAAALNAAMHFEIDDVVDPAETRGLIAATLAAATAAPRDRP
MAB_4676|M.abscessus_ATCC_1997 RQATAAAQENAKAINAAQIFEIDDVIDPAETRSLVASTFAAAMREPLPLR
MSMEG_6577|M.smegmatis_MC2_155 RAATKAAEEHAKALNSASMFEIDDVIDPAETRSVIISTLVAAAHHEHANR
MMAR_1951|M.marinum_M DRLVQAAYQHGKALRSATTFELDDVIDPAESRAWITRLPGR---------
MAV_3657|M.avium_104 DRLVAAAYQHGKALRAATTFELDDVIDPAASRAWITRLSEG---------
Mb3829c|M.bovis_AF2122/97 SFVENYNLNMAIPWIAAERGFIDAVIDPHETRLLLRKSMHLLRDKQLWWR
Rv3799c|M.tuberculosis_H37Rv SFVENYNLNMAIPWIAAERGFIDAVIDPHETRLLLRKSMHLLRDKQLWWR
MLBr_00102|M.leprae_Br4923 TFVDNYNLNMAIPWIAAERGFIDAVVEPHQTRLLLRKSLHLLRDKQQWWR
MUL_3864|M.ulcerans_Agy99 --AKLRNAELQASYRSAEQMGFDELIDPRETRDALLAALQRGIYHRQAAA
. . :* :* :::* :* :
Mflv_0781|M.gilvum_PYR-GCK PDRS---RFIDTW
Mvan_0066|M.vanbaalenii_PYR-1 PGGSRFGRFVDTW
TH_2343|M.thermoresistible__bu PR-----RFVDTW
MAB_4676|M.abscessus_ATCC_1997 RS------VVDTW
MSMEG_6577|M.smegmatis_MC2_155 PR------FVDTW
MMAR_1951|M.marinum_M -------------
MAV_3657|M.avium_104 -------------
Mb3829c|M.bovis_AF2122/97 VGRKHGLIPV---
Rv3799c|M.tuberculosis_H37Rv VGRKHGLIPV---
MLBr_00102|M.leprae_Br4923 VGRKHGLIPL---
MUL_3864|M.ulcerans_Agy99 EPVSRTLIMP---