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TASLLVANRGEIALRIIRTATELGMRTVAVYAADDAHSPHVHAADEAMPLPGSGPPAYLNQAALLAVAEN TGATLIHPGYGFLSENAEFAEACAAARRTFVGPDARVLELLGNKTAARRAAIAAEVPTLAATDGPSGVED IEAFFAAHPGGIMIKALAGGGGRGMRKVHNAAQIAGAYQRCAAEARLGFGDPALFAEALLGDARHIEVQV VAAPAGHQTHALAVGDRDCSIQRRYQKLIEIAPAQGLSEELRRALHQAAVRLCARVGLRGLATVEFLVSG ERFVFLEVNPRIQVEHTVTEQTTGLDLVAVQLAIAGGESYYRLGLPAGIASDGTEVIGEPAAQRGIAIQL RVNAETFGADFSVLPSAGTLTAFCPPSGRGVRVDTYGRPGLVVSPQYDSLLAKVIVAVHGSSWRAAMRKA DTALSEFGVEGVATNIGFLRRLLAEQRLETGWVNTDFVDDKLPELAAAALTHQPGPQPGAVELYPGEDAL RAQLAGTVVEVAPEGADYPAGAQLVVLEAMKMQHVLAAPDALRTVRVLVTPGQVVGTGDPLLVFTRTTGG DDGESETAATDLDLTRADLDEVIERHARTLDEGRPDAVAKRHRQGRRTARENIDDLVDPGSFVEYGALAI AAQRSRRSEEDLIANTPADGLVAGLATVGADRFGRAAAQAVVASYDYTVLAGTQGMRNHAKTDRVFDLAA RKRLPVVLFAEGGGGRPGDTDVGGAAGLDVPTFRMLAGLRGRVPLVSVVSGRCFAGNAALAGVCDVIIAT PDANIGMGGPAMIEGGGLGVYPPEAIGPIAVQRRNGVVGLVARDEAHAVSLAKQYLSYFQGRLDRWQAPD PRVARHVVPQNRLRAYDVHRAIEAIVDVGSVLELRPDYGVGIVTALVRVEGVPCGLIANSTHHLGGAIDA EAADKAGDFLALCESFGLPVISLCDTPGFMVGPDAETQAAVRRFGRMFVLGARLTVPLGMIILRKGYGLG AMAMAGGSFRAPQFTVAWPTGEIGGMGLEGAVRLGYRKELAAVTDPAERQNLFDRLVAAAYQHGKALRAA TTFELDDVIDPAASRAWITRLSEG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3657 | - | - | 100% (1075) | carbamoyl-phosphate synthase/carboxyl transferase |
| M. avium 104 | MAV_4255 | - | 2e-90 | 38.66% (582) | acetyl-/propionyl-coenzyme A carboxylase alpha chain |
| M. avium 104 | MAV_1671 | - | 4e-90 | 43.53% (487) | acetyl-/propionyl-coenzyme A carboxylase alpha chain |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3313 | accA3 | 5e-96 | 38.45% (606) | bifunctional acetyl-/propionyl-coenzyme A carboxylase |
| M. gilvum PYR-GCK | Mflv_0781 | - | 1e-152 | 57.40% (493) | propionyl-CoA carboxylase |
| M. tuberculosis H37Rv | Rv3285 | accA3 | 5e-96 | 38.45% (606) | bifunctional acetyl-/propionyl-coenzyme A carboxylase |
| M. leprae Br4923 | MLBr_00726 | bccA | 2e-94 | 39.38% (584) | acetyl/propionyl CoA carboxylase alpha subunit |
| M. abscessus ATCC 19977 | MAB_4676 | - | 1e-153 | 56.80% (493) | putative carboxyl transferase/pyruvate carboxylase |
| M. marinum M | MMAR_1951 | accA3_1 | 0.0 | 78.94% (1073) | bifunctional protein acetyl-/propionyl-coenzyme A |
| M. smegmatis MC2 155 | MSMEG_6577 | - | 1e-150 | 56.71% (499) | methylmalonyl-CoA carboxyltransferase 12S subunit |
| M. thermoresistible (build 8) | TH_2343 | - | 1e-153 | 57.40% (493) | methylmalonyl-CoA carboxyltransferase 12S subunit |
| M. ulcerans Agy99 | MUL_2637 | accA3 | 4e-95 | 39.62% (583) | bifunctional protein acetyl-/propionyl-coenzyme a |
| M. vanbaalenii PYR-1 | Mvan_0066 | - | 1e-151 | 57.46% (496) | propionyl-CoA carboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M --MTLLIANRGEIALRIIRTANELGIATVAVYAEDDAETPHVHAADEAIG
MAV_3657|M.avium_104 MTASLLVANRGEIALRIIRTATELGMRTVAVYAADDAHSPHVHAADEAMP
Mb3313|M.bovis_AF2122/97 --------------------------------------------------
Rv3285|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2637|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00726|M.leprae_Br4923 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M LPGKGASAYLDRAAILAAAAKAGARLIHPGYGFLSENSEFVWACTAAGYT
MAV_3657|M.avium_104 LPGSGPPAYLNQAALLAVAENTGATLIHPGYGFLSENAEFAEACAAARRT
Mb3313|M.bovis_AF2122/97 --------------------------------------------------
Rv3285|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2637|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00726|M.leprae_Br4923 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M FVGPDADVLDLVGNKASARGVATAAGVPVLAATEGPSSVEDVRAFFADQD
MAV_3657|M.avium_104 FVGPDARVLELLGNKTAARRAAIAAEVPTLAATDGPSGVEDIEAFFAAHP
Mb3313|M.bovis_AF2122/97 --------------------------------------------------
Rv3285|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2637|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00726|M.leprae_Br4923 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M GGIMIKALAGGGGRGMRKVECGDQIDNAYRQCAAEAQLGFGNPALFAEAL
MAV_3657|M.avium_104 GGIMIKALAGGGGRGMRKVHNAAQIAGAYQRCAAEARLGFGDPALFAEAL
Mb3313|M.bovis_AF2122/97 --------------------------------------------------
Rv3285|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2637|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00726|M.leprae_Br4923 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M LHNARHIEVQVVAAPVGHQTRALALGDRDCSIQRRYQKLVEIAPAQQLSD
MAV_3657|M.avium_104 LGDARHIEVQVVAAPAGHQTHALAVGDRDCSIQRRYQKLIEIAPAQGLSE
Mb3313|M.bovis_AF2122/97 --------------------------------------------------
Rv3285|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2637|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00726|M.leprae_Br4923 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M LLRRQLHQAAARLCARVGLRGVATVEFLVAGDKFVFLEINPRIQVEHTIT
MAV_3657|M.avium_104 ELRRALHQAAVRLCARVGLRGLATVEFLVSGERFVFLEVNPRIQVEHTVT
Mb3313|M.bovis_AF2122/97 --------------------------------------------------
Rv3285|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2637|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00726|M.leprae_Br4923 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M EEVTGVDLVAAQLAIAGGASYYELGHQLGLPAGIASDGSEVIGEPAVRRG
MAV_3657|M.avium_104 EQTTGLDLVAVQLAIAGGESYYRLG----LPAGIASDGTEVIGEPAAQRG
Mb3313|M.bovis_AF2122/97 --------------------------------------------------
Rv3285|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2637|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00726|M.leprae_Br4923 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M IAIQTRINMETLAADGSVSPATGTLNVFSPPSGPGVRVDTYGRPGLVPSP
MAV_3657|M.avium_104 IAIQLRVNAETFGADFSVLPSAGTLTAFCPPSGRGVRVDTYGRPGLVVSP
Mb3313|M.bovis_AF2122/97 --------------------------------------------------
Rv3285|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2637|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00726|M.leprae_Br4923 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M LYDSLLAKVITHVHGSSFPAALRKARTVLSDFSIEGIATNAGLLREVLSD
MAV_3657|M.avium_104 QYDSLLAKVIVAVHGSSWRAAMRKADTALSEFGVEGVATNIGFLRRLLAE
Mb3313|M.bovis_AF2122/97 --------------------------------------------------
Rv3285|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2637|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00726|M.leprae_Br4923 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M ERLVSGVVPTTFLDEILPALVEAAQSQQREVRVVALELYPGEQALRAQMA
MAV_3657|M.avium_104 QRLETGWVNTDFVDDKLPELAAAALTHQPGPQPGAVELYPGEDALRAQLA
Mb3313|M.bovis_AF2122/97 --------------------------------------------------
Rv3285|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2637|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00726|M.leprae_Br4923 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0066|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2343|M.thermoresistible__bu --------------------------------------------------
MAB_4676|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6577|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1951|M.marinum_M GTVVEVPPEGVDIGAGDQLVVLEAMKMQHVLAAPHRLHTVRILVTPGQVV
MAV_3657|M.avium_104 GTVVEVAPEGADYPAGAQLVVLEAMKMQHVLAAPDALRTVRVLVTPGQVV
Mb3313|M.bovis_AF2122/97 --------------------------------------------------
Rv3285|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2637|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00726|M.leprae_Br4923 --------------------------------------------------
Mflv_0781|M.gilvum_PYR-GCK -----------------------MPEPEPVRDDLTELQRRRALTEDAARP
Mvan_0066|M.vanbaalenii_PYR-1 -------------------------MPDPIRDDLAELWRRRALTEDAARP
TH_2343|M.thermoresistible__bu -----------------------------MRPELAELLGRRRLTTDAARP
MAB_4676|M.abscessus_ATCC_1997 ------------------------MADEQLREDHVELLARRALTEDAARP
MSMEG_6577|M.smegmatis_MC2_155 ------------------------MTDEDLRDDLAEVLRRRALTQDDARP
MMAR_1951|M.marinum_M ATGDPLVVFCRTDAGEDVESSLAAVDLDRSRADLEEVRARHRLTLDEGRE
MAV_3657|M.avium_104 GTGDPLLVFTRTTGGDDGESETAATDLDLTRADLDEVIERHARTLDEGRP
Mb3313|M.bovis_AF2122/97 -------MASHAGSRIARISKVLVANRGEIAVRVIRAARDAGLPSVAVYA
Rv3285|M.tuberculosis_H37Rv -------MASHAGSRIARISKVLVANRGEIAVRVIRAARDAGLPSVAVYA
MUL_2637|M.ulcerans_Agy99 -------MASHASS---RISKVLVANRGEIAVRVIRAARDAGLASVAVYA
MLBr_00726|M.leprae_Br4923 -------MASHASS---RIAKVLVANRGEIAVRVIRAARDARLPSVAVYA
. .
Mflv_0781|M.gilvum_PYR-GCK DAVQRRHDAGGRTARENVADLVDPGSFVEYGRFAVAPQRMRRDVEDLIAR
Mvan_0066|M.vanbaalenii_PYR-1 DAVERRHAAGGRTARENVADLVDTGSFVEYGRFAIAPQRMRRDVEDLITR
TH_2343|M.thermoresistible__bu EAVQRRHGAGGRTARENIEDLVDPGSFVEYGRFVVAAQRQRRDLADLIAR
MAB_4676|M.abscessus_ATCC_1997 DAVARRHAAGGRTARENISDLVDAGSFVEYGRFAIAAQRRRRELADLIAR
MSMEG_6577|M.smegmatis_MC2_155 DAVERRRASGARTARQNIADLVDDGSFVEYGRFAIAAQRQRRSLDDLIAR
MMAR_1951|M.marinum_M LAVGKRHKQGRRTARENIADLVDAGSFVEYGALAIAAQRSRRSEEDLIVS
MAV_3657|M.avium_104 DAVAKRHRQGRRTARENIDDLVDPGSFVEYGALAIAAQRSRRSEEDLIAN
Mb3313|M.bovis_AF2122/97 EPDAESPHVRLADEAFALGGQTSAESYLDFAKILDAAAKSGANAIHPGYG
Rv3285|M.tuberculosis_H37Rv EPDAESPHVRLADEAFALGGQTSAESYLDFAKILDAAAKSGANAIHPGYG
MUL_2637|M.ulcerans_Agy99 EPDAEAPHVSLADEAFALGGQTSAESYLDFEKLLDAATKSGANAIHPGYG
MLBr_00726|M.leprae_Br4923 EPDAEAPHVRLADEAFALGGHTSAESYLDFGKILDAAAKSGANAIHPGYG
. . : . .. *:::: : *. : . .
Mflv_0781|M.gilvum_PYR-GCK TPADGLIAGTARING-------DACAVLSYDYTVLAGTQGGLGHR-----
Mvan_0066|M.vanbaalenii_PYR-1 TPADGLVAGTARVDG-------HPCAVLSYDYTVLAGTQGALGHR-----
TH_2343|M.thermoresistible__bu TPADGLVAGTARING-------RPAAVLSYDYTVLAGTQGVFGHF-----
MAB_4676|M.abscessus_ATCC_1997 TPADGLVAGTARVNGNLFGADRSACAVLSYDYTVLAGTQGALGHH-----
MSMEG_6577|M.smegmatis_MC2_155 TPADGLVAGTARVDG-------QPCAVLSYDYTVLAGTQGALGHL-----
MMAR_1951|M.marinum_M TPADGLVAGLATIGADRFGNNAAEAVVVSYDYTVLAGTQGMRNHA-----
MAV_3657|M.avium_104 TPADGLVAGLATVGADRFGRAAAQAVVASYDYTVLAGTQGMRNHA-----
Mb3313|M.bovis_AF2122/97 FLAENADFAQAVIDAGLIWIGPSPQSIRDLGDKVTARHIAARAQAPLVPG
Rv3285|M.tuberculosis_H37Rv FLAENADFAQAVIDAGLIWIGPSPQSIRDLGDKVTARHIAARAQAPLVPG
MUL_2637|M.ulcerans_Agy99 FLSENADFAQAVIDAGLIWIGPSPQSIRDLGDKVTARHIAARAKAPLVPG
MLBr_00726|M.leprae_Br4923 FLAENADFAQAVIDAGLIWIGPSPQSIRDLGDKVTARHIAARAQAPLVPG
::. . * :.. : . . .* * . :
Mflv_0781|M.gilvum_PYR-GCK ------KKDRLFELIERMALPTVFFAEGGGGRPVDTDYPVVSALDTRAFA
Mvan_0066|M.vanbaalenii_PYR-1 ------KKDRLFELIERMQLPTVFFAEGGGGRPGDTDYPVVSALDTRAFA
TH_2343|M.thermoresistible__bu ------KKDRLFDLIERMRLPTVFFAEGGGGRPGDTDHPTVSSLQVRAFK
MAB_4676|M.abscessus_ATCC_1997 ------KKDRLFDLIERMKLPTVFFAEGGGGRPGDTDYPVVSMLDVRAFK
MSMEG_6577|M.smegmatis_MC2_155 ------KKDRLFDLIERMRLPTVFFAEGGGGRPGDTDIPTVSSLDVRAFK
MMAR_1951|M.marinum_M ------KTDRVFGLAARKRIPVVLFAEGGGGRPGDTDLGNISGLDVPTFR
MAV_3657|M.avium_104 ------KTDRVFDLAARKRLPVVLFAEGGGGRPGDTDVGGAAGLDVPTFR
Mb3313|M.bovis_AF2122/97 TPDPVKGADEVVAFAEEYGLPIAIKAAHGGGGKGMKVARTIDEIPELYES
Rv3285|M.tuberculosis_H37Rv TPDPVKGADEVVAFAEEYGLPIAIKAAHGGGGKGMKVARTIDEIPELYES
MUL_2637|M.ulcerans_Agy99 TPDPVKNAEEVVAFAQEYGLPIAIKAAFGGGGRGMKVARTVEEIPELYES
MLBr_00726|M.leprae_Br4923 TPDPVKNADEVVAFAKEHGVPIAIKAAFGGGGKGMKVARTLEEISELYES
:.:. : . :* .: * *** . :
Mflv_0781|M.gilvum_PYR-GCK LWAKLSGQVPRIAVVKGRCFA--------------GNAVIAGASDLIVAT
Mvan_0066|M.vanbaalenii_PYR-1 LWARLSGVVPRIAIVKGRCFA--------------GNAVIAGASDLIVAT
TH_2343|M.thermoresistible__bu LWAGLSGLVPRIAVVKGRCFA--------------GNAVIAGAADLIVAT
MAB_4676|M.abscessus_ATCC_1997 LWAALSGVVPRISVVNGRCFA--------------GNAVIAGCSDLIVAT
MSMEG_6577|M.smegmatis_MC2_155 LWAALSGLVPRIAVVRGRCFA--------------GNAVIAGAADLIVAT
MMAR_1951|M.marinum_M MLAGLSGRVPLVSIVSGRCFA--------------GNAALAGVCDVIIAT
MAV_3657|M.avium_104 MLAGLRGRVPLVSVVSGRCFA--------------GNAALAGVCDVIIAT
Mb3313|M.bovis_AF2122/97 AVREATAAFGRGECYVERYLDKPRHVEAQVIADQHGNVVVAGTRDCSLQR
Rv3285|M.tuberculosis_H37Rv AVREATAAFGRGECYVERYLDKPRHVEAQVIADQHGNVVVAGTRDCSLQR
MUL_2637|M.ulcerans_Agy99 AVREATAAFGRGECFVERYLDRPRHVEAQVIADQHGNVVVAGTRDCSLQR
MLBr_00726|M.leprae_Br4923 AVREATVAFGRGECFVERYLDKPRHVEAQVIADQHGNIVVAGTRDCSLQR
. * : ** .:** * :
Mflv_0781|M.gilvum_PYR-GCK RDASLGMGGPAMIA----------------------GGGLGAVAPDDVGP
Mvan_0066|M.vanbaalenii_PYR-1 RDASLGMGGPAMIA----------------------GGGLGDVPPDEVGP
TH_2343|M.thermoresistible__bu ADTSIGMGGPAMIA----------------------GGGLGDVHPDEVGP
MAB_4676|M.abscessus_ATCC_1997 KDTSIGMGGPAMIA----------------------GGGLGEVHPDEVGP
MSMEG_6577|M.smegmatis_MC2_155 EDASIGMGGPAMIA----------------------GGGLGEVAPEDVGP
MMAR_1951|M.marinum_M PDANIGMGGPAMIE----------------------GGGLGVYPPEAIGP
MAV_3657|M.avium_104 PDANIGMGGPAMIE----------------------GGGLGVYPPEAIGP
Mb3313|M.bovis_AF2122/97 RYQKLVEEAPAPFLTDFQRKEIHDSAKRICKEAHYHGAGTVEYLVGQDGL
Rv3285|M.tuberculosis_H37Rv RYQKLVEEAPAPFLTDFQRKEIHDSAKRICKEAHYHGAGTVEYLVGQDGL
MUL_2637|M.ulcerans_Agy99 RYQKLVEEAPAPFLSDAQRKEIHESAKRICKEAHYYGAGTVEYLVGQDGL
MLBr_00726|M.leprae_Br4923 RFQKLVEEAPAPFLTDAQRKEIHESAKRICKEAHYYGAGTVEYLVGQDGL
.: .** : *.* *
Mflv_0781|M.gilvum_PYR-GCK MSVQEPNGNVDVVVDDEAAAVAVAKRLIGYFQGCVSQWSAPDQTPLRTAV
Mvan_0066|M.vanbaalenii_PYR-1 MTTQEPNGNVDVVVDDEAEAVAVTKTLLGYFQGPADSWSAPDQTVLRTAV
TH_2343|M.thermoresistible__bu ISVQEPNGVVDLVVADETEAVAAARRLLGYFQGSTAPGEVADQTVLRTMV
MAB_4676|M.abscessus_ATCC_1997 IAVQSTNGVVDVVVDDEEQAVTVAKRLISYFQGAVAPGDGADQTALRTMI
MSMEG_6577|M.smegmatis_MC2_155 ISVQAPNGVVDIVVADEPEAVAVTKTLLGYFGGPVDAGPERDQTPLRTMV
MMAR_1951|M.marinum_M IDVQRRNGVVSLVARDEAHAVSLAKRYLGYFQGKVEGWQAPDPRLARQVV
MAV_3657|M.avium_104 IAVQRRNGVVGLVARDEAHAVSLAKQYLSYFQGRLDRWQAPDPRVARHVV
Mb3313|M.bovis_AF2122/97 ISFLEVNTRLQVEHPVTEETAGIDLVLQQFRIANGEKLDITEDPTPRGHA
Rv3285|M.tuberculosis_H37Rv ISFLEVNTRLQVEHPVTEETAGIDLVLQQFRIANGEKLDITEDPTPRGHA
MUL_2637|M.ulcerans_Agy99 ISFLEVNTRLQVEHPVTEETAGIDLVREQFRIANGEKLDLTEDPTPRGHA
MLBr_00726|M.leprae_Br4923 ISFLEVNTRLQVEHPVTEETTGIDLVLQQFKIANGEKLELIKDPIPCGHA
: * : : :. : . .
Mflv_0781|M.gilvum_PYR-GCK PERARRAYDVAPVIETLADEDSVTFLRPRFAREMVTALARIEGRPVGVIA
Mvan_0066|M.vanbaalenii_PYR-1 PDRARRAYDVAPVIETIADEDSVTFLRPRFAREMVTALARVEGRPVGVIA
TH_2343|M.thermoresistible__bu PERARRAYDVTPVIETLADADSVTVLRPRFAREMVTALARIDGRPVGVLA
MAB_4676|M.abscessus_ATCC_1997 PERARRAYPIRPIIETLADTGSVTFLREKFAPEMATALARIEGRPIGVLA
MSMEG_6577|M.smegmatis_MC2_155 PERARRAYPVGPVIETLADEGSVTYLREKFAPEMVTAFARMAGRPVGILA
MMAR_1951|M.marinum_M PENRLRAYDVHRAIESIVDVGSVLELRADYGVGIVTALVRIEGFAYGLIA
MAV_3657|M.avium_104 PQNRLRAYDVHRAIEAIVDVGSVLELRPDYGVGIVTALVRVEGVPCGLIA
Mb3313|M.bovis_AF2122/97 IEFRINGEDAG--RNFLPAPGPVTKFHPPSGPGVRVDSGVETGSVIGGQF
Rv3285|M.tuberculosis_H37Rv IEFRINGEDAG--RNFLPAPGPVTKFHPPSGPGVRVDSGVETGSVIGGQF
MUL_2637|M.ulcerans_Agy99 IEFRINGEDAG--RGFLPAPGPVTKFHPPAGPGVRMDSGVETGSVIGGQF
MLBr_00726|M.leprae_Br4923 IEFRINGEDAG--RNFLPSPGPVSKFHPPTGPGVRLDSGVETGSVIGGQF
: .. : ..* :: . : * *
Mflv_0781|M.gilvum_PYR-GCK N---DTRFTAGAITAAASDKAARFLQLCDAFGLPVVS-----LIDCPGYM
Mvan_0066|M.vanbaalenii_PYR-1 N---DTRFTAGAITAAASDKAARFLQLCDAFGFPVVS-----LIDCPGYM
TH_2343|M.thermoresistible__bu N---DTRYMAGAITAAASDKAARFLQLCDVFGLPVIS-----LIDCPGYM
MAB_4676|M.abscessus_ATCC_1997 N---NSMVMAGAITAAASDKAARFLQLCDAFGLPVLS-----LVDCPGYM
MSMEG_6577|M.smegmatis_MC2_155 N---NTMVMAGAITATASDKAARFLQLCDAFGIPVVS-----LVDCPGYM
MMAR_1951|M.marinum_M N---SSHHLGGAIDAEASDKVTDFLMLCESFRLPVIS-----LCDTPGFM
MAV_3657|M.avium_104 N---STHHLGGAIDAEAADKAGDFLALCESFGLPVIS-----LCDTPGFM
Mb3313|M.bovis_AF2122/97 DSMLAKLIVHGADRAEALARARRALNEFGVEGLATVIPFHRAVVSDPAFI
Rv3285|M.tuberculosis_H37Rv DSMLAKLIVHGADRAEALARARRALNEFGVEGLATVIPFHRAVVSDPAFI
MUL_2637|M.ulcerans_Agy99 DSMLAKLIVYGANRTEALERARRALAEFQVEGLATVIPFHRAVVSDPAFI
MLBr_00726|M.leprae_Br4923 DSMLAKLIVHGATRQEALARARRALDEFEVEGLATVIPFHRAVVSDPALI
: . ** * :. * :..: : . *. :
Mflv_0781|M.gilvum_PYR-GCK VGPAAEAESLVRRASRMLVAGAALRVPLIAVILRRGYGLGAQAMAGGSLH
Mvan_0066|M.vanbaalenii_PYR-1 VGPAAEAESLVRRASRMLVAGAALCVPMVAVILRRGYGLGAQAMAGGSLH
TH_2343|M.thermoresistible__bu VGPAAEAEALVRRGSRLLVAGAALRVPLIAVVLRRGYGLGAQAMAGGGLH
MAB_4676|M.abscessus_ATCC_1997 VGPAAEAEALVRRASRMLVAGAALRVPLVSVILRRGYGLGAQAMTGGSLH
MSMEG_6577|M.smegmatis_MC2_155 VGPAAEAEALVRRGSRLLVAGAALTVPLIAVILRRGYGLGAQAMCGGSLH
MMAR_1951|M.marinum_M VGPDAETQASVRRFGRMFLAGARLTVPLGMIILRKGYGLGAMAMAGGSFH
MAV_3657|M.avium_104 VGPDAETQAAVRRFGRMFVLGARLTVPLGMIILRKGYGLGAMAMAGGSFR
Mb3313|M.bovis_AF2122/97 GDANGFSVHTRWIETEWNNTIEPFTDGEPLD-EDARPRQKVVVEIDGRRV
Rv3285|M.tuberculosis_H37Rv GDANGFSVHTRWIETEWNNTIEPFTDGEPLD-EDARPRQKVVVEIDGRRV
MUL_2637|M.ulcerans_Agy99 GDEHGFSVHTRWIETEWNNTIEPFTAGEPLDDEDFRPRQTVVVEIDGRRV
MLBr_00726|M.leprae_Br4923 GDNNSFSVHTRWIETEWNNTIEPFIDNQPLDEEDTRPQQTVIVEVDGRRL
. . : . : . . .*
Mflv_0781|M.gilvum_PYR-GCK EPLLTVAWPGAHLGPMGLEGAVRLGMRKELEAIADEAEREARVVAATAAA
Mvan_0066|M.vanbaalenii_PYR-1 EPVLTVAWPGAHLGPMGLEGAVRLGMRKELDAIEDEQEREERVRLATAAA
TH_2343|M.thermoresistible__bu EPVLTVAWPGAHLGPMGLEGAVRLGMRKELEAIADEAEREERVRQATAAA
MAB_4676|M.abscessus_ATCC_1997 EPLLTVAWPNAHLGPMGLEGAVRLGLRKELEAIADESAREEAVRQATAAA
MSMEG_6577|M.smegmatis_MC2_155 EPLLTVAWPGAHLGPMGLEGAVRLGMRKELEAIENEGAREEAVRAATKAA
MMAR_1951|M.marinum_M APEFTIAWPTGEIGGMGLEGAVRLGFSKELAAAADDIERQELFDRLVQAA
MAV_3657|M.avium_104 APQFTVAWPTGEIGGMGLEGAVRLGYRKELAAVTDPAERQNLFDRLVAAA
Mb3313|M.bovis_AF2122/97 EVSLPADLALSNGGGCDPVGVIRRKPKPRKRGAHTGAAASGDAVTAPMQG
Rv3285|M.tuberculosis_H37Rv EVSLPADLALSNGGGCDPVGVIRRKPKPRKRGAHTGAAASGDAVTAPMQG
MUL_2637|M.ulcerans_Agy99 EVSLPADLAMSNGSGAD-AGVIRRKPKPRKRGAHTGAAASGDAVTAPMQG
MLBr_00726|M.leprae_Br4923 EVSLPADLALANPAGCNPAGVIRKKPKPRKRGGHTGAATSGDAVTAPMQG
:. . .. . . *.:* . . . .
Mflv_0781|M.gilvum_PYR-GCK QEYAKALNAAMLFEIDDVIDPAETRAVIAATLVAADSGTKKPAPDRS---
Mvan_0066|M.vanbaalenii_PYR-1 QENAKALNAAMLFEIDDVIDPAETRAVIAATFAAADTDTRKPAPGGSRFG
TH_2343|M.thermoresistible__bu QRHAAALNAAMHFEIDDVVDPAETRGLIAATLAAATAAPRDRPPR-----
MAB_4676|M.abscessus_ATCC_1997 QENAKAINAAQIFEIDDVIDPAETRSLVASTFAAAMREPLPLRRS-----
MSMEG_6577|M.smegmatis_MC2_155 EEHAKALNSASMFEIDDVIDPAETRSVIISTLVAAAHHEHANRPR-----
MMAR_1951|M.marinum_M YQHGKALRSATTFELDDVIDPAESRAWITRLPGR----------------
MAV_3657|M.avium_104 YQHGKALRAATTFELDDVIDPAASRAWITRLSEG----------------
Mb3313|M.bovis_AF2122/97 TVVKFAVEEGQEVVAGDLVVVLEAMKMENPVTAHKDGTITGLAVEAGAAI
Rv3285|M.tuberculosis_H37Rv TVVKFAVEEGQEVVAGDLVVVLEAMKMENPVTAHKDGTITGLAVEAGAAI
MUL_2637|M.ulcerans_Agy99 TVVKVAVEEGQEVVVGELVVVLEAMKMENPVTAHKDGVITGLAVEAGAAI
MLBr_00726|M.leprae_Br4923 TVVKVAVAEGQTVMTGDLVVVLEAMKMENPVTAHKDGIITGLAVEAGTAI
*: . . .::: :
Mflv_0781|M.gilvum_PYR-GCK RFIDTW----
Mvan_0066|M.vanbaalenii_PYR-1 RFVDTW----
TH_2343|M.thermoresistible__bu RFVDTW----
MAB_4676|M.abscessus_ATCC_1997 -VVDTW----
MSMEG_6577|M.smegmatis_MC2_155 -FVDTW----
MMAR_1951|M.marinum_M ----------
MAV_3657|M.avium_104 ----------
Mb3313|M.bovis_AF2122/97 TQGTVLAEIK
Rv3285|M.tuberculosis_H37Rv TQGTVLAEIK
MUL_2637|M.ulcerans_Agy99 TQGTVLAEIK
MLBr_00726|M.leprae_Br4923 TQGTVLAEIK