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MTDEDLRDDLAEVLRRRALTQDDARPDAVERRRASGARTARQNIADLVDDGSFVEYGRFAIAAQRQRRSL DDLIARTPADGLVAGTARVDGQPCAVLSYDYTVLAGTQGALGHLKKDRLFDLIERMRLPTVFFAEGGGGR PGDTDIPTVSSLDVRAFKLWAALSGLVPRIAVVRGRCFAGNAVIAGAADLIVATEDASIGMGGPAMIAGG GLGEVAPEDVGPISVQAPNGVVDIVVADEPEAVAVTKTLLGYFGGPVDAGPERDQTPLRTMVPERARRAY PVGPVIETLADEGSVTYLREKFAPEMVTAFARMAGRPVGILANNTMVMAGAITATASDKAARFLQLCDAF GIPVVSLVDCPGYMVGPAAEAEALVRRGSRLLVAGAALTVPLIAVILRRGYGLGAQAMCGGSLHEPLLTV AWPGAHLGPMGLEGAVRLGMRKELEAIENEGAREEAVRAATKAAEEHAKALNSASMFEIDDVIDPAETRS VIISTLVAAAHHEHANRPRFVDTW
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_6577 | - | - | 100% (514) | methylmalonyl-CoA carboxyltransferase 12S subunit |
M. smegmatis MC2 155 | MSMEG_6391 | - | 4e-59 | 31.79% (519) | propionyl-CoA carboxylase beta chain |
M. smegmatis MC2 155 | MSMEG_4329 | - | 3e-54 | 32.89% (450) | propionyl-CoA carboxylase beta chain |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3829c | accD4 | 3e-55 | 32.09% (508) | propionyl-CoA carboxylase beta chain |
M. gilvum PYR-GCK | Mflv_0781 | - | 0.0 | 77.63% (514) | propionyl-CoA carboxylase |
M. tuberculosis H37Rv | Rv3799c | accD4 | 4e-55 | 32.09% (508) | propionyl-CoA carboxylase beta chain |
M. leprae Br4923 | MLBr_00731 | accD5 | 5e-54 | 30.51% (508) | acetyl/propionyl CoA carboxylase beta subunit |
M. abscessus ATCC 19977 | MAB_4676 | - | 0.0 | 78.12% (521) | putative carboxyl transferase/pyruvate carboxylase |
M. marinum M | MMAR_1951 | accA3_1 | 1e-148 | 55.98% (493) | bifunctional protein acetyl-/propionyl-coenzyme A |
M. avium 104 | MAV_3657 | - | 1e-151 | 56.71% (499) | carbamoyl-phosphate synthase/carboxyl transferase |
M. thermoresistible (build 8) | TH_2343 | - | 0.0 | 79.02% (510) | methylmalonyl-CoA carboxyltransferase 12S subunit |
M. ulcerans Agy99 | MUL_4982 | accD4_1 | 2e-56 | 30.66% (512) | propionyl-CoA carboxylase beta chain 4 AccD4_1 |
M. vanbaalenii PYR-1 | Mvan_0066 | - | 0.0 | 77.56% (517) | propionyl-CoA carboxylase |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_6577|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4676|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_0781|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0066|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_2343|M.thermoresistible__bu -------------------------------------------------- MMAR_1951|M.marinum_M --MTLLIANRGEIALRIIRTANELGIATVAVYAEDDAETPHVHAADEAIG MAV_3657|M.avium_104 MTASLLVANRGEIALRIIRTATELGMRTVAVYAADDAHSPHVHAADEAMP Mb3829c|M.bovis_AF2122/97 -------------------------------------------------- Rv3799c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_4982|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00731|M.leprae_Br4923 -------------------------------------------------- MSMEG_6577|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4676|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_0781|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0066|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_2343|M.thermoresistible__bu -------------------------------------------------- MMAR_1951|M.marinum_M LPGKGASAYLDRAAILAAAAKAGARLIHPGYGFLSENSEFVWACTAAGYT MAV_3657|M.avium_104 LPGSGPPAYLNQAALLAVAENTGATLIHPGYGFLSENAEFAEACAAARRT Mb3829c|M.bovis_AF2122/97 -------------------------------------------------- Rv3799c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_4982|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00731|M.leprae_Br4923 -------------------------------------------------- MSMEG_6577|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4676|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_0781|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0066|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_2343|M.thermoresistible__bu -------------------------------------------------- MMAR_1951|M.marinum_M FVGPDADVLDLVGNKASARGVATAAGVPVLAATEGPSSVEDVRAFFADQD MAV_3657|M.avium_104 FVGPDARVLELLGNKTAARRAAIAAEVPTLAATDGPSGVEDIEAFFAAHP Mb3829c|M.bovis_AF2122/97 -------------------------------------------------- Rv3799c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_4982|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00731|M.leprae_Br4923 -------------------------------------------------- MSMEG_6577|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4676|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_0781|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0066|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_2343|M.thermoresistible__bu -------------------------------------------------- MMAR_1951|M.marinum_M GGIMIKALAGGGGRGMRKVECGDQIDNAYRQCAAEAQLGFGNPALFAEAL MAV_3657|M.avium_104 GGIMIKALAGGGGRGMRKVHNAAQIAGAYQRCAAEARLGFGDPALFAEAL Mb3829c|M.bovis_AF2122/97 -------------------------------------------------- Rv3799c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_4982|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00731|M.leprae_Br4923 -------------------------------------------------- MSMEG_6577|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4676|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_0781|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0066|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_2343|M.thermoresistible__bu -------------------------------------------------- MMAR_1951|M.marinum_M LHNARHIEVQVVAAPVGHQTRALALGDRDCSIQRRYQKLVEIAPAQQLSD MAV_3657|M.avium_104 LGDARHIEVQVVAAPAGHQTHALAVGDRDCSIQRRYQKLIEIAPAQGLSE Mb3829c|M.bovis_AF2122/97 -------------------------------------------------- Rv3799c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_4982|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00731|M.leprae_Br4923 -------------------------------------------------- MSMEG_6577|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4676|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_0781|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0066|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_2343|M.thermoresistible__bu -------------------------------------------------- MMAR_1951|M.marinum_M LLRRQLHQAAARLCARVGLRGVATVEFLVAGDKFVFLEINPRIQVEHTIT MAV_3657|M.avium_104 ELRRALHQAAVRLCARVGLRGLATVEFLVSGERFVFLEVNPRIQVEHTVT Mb3829c|M.bovis_AF2122/97 -------------------------------------------------- Rv3799c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_4982|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00731|M.leprae_Br4923 -------------------------------------------------- MSMEG_6577|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4676|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_0781|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0066|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_2343|M.thermoresistible__bu -------------------------------------------------- MMAR_1951|M.marinum_M EEVTGVDLVAAQLAIAGGASYYELGHQLGLPAGIASDGSEVIGEPAVRRG MAV_3657|M.avium_104 EQTTGLDLVAVQLAIAGGESYYRLG----LPAGIASDGTEVIGEPAAQRG Mb3829c|M.bovis_AF2122/97 -------------------------------------------------- Rv3799c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_4982|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00731|M.leprae_Br4923 -------------------------------------------------- MSMEG_6577|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4676|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_0781|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0066|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_2343|M.thermoresistible__bu -------------------------------------------------- MMAR_1951|M.marinum_M IAIQTRINMETLAADGSVSPATGTLNVFSPPSGPGVRVDTYGRPGLVPSP MAV_3657|M.avium_104 IAIQLRVNAETFGADFSVLPSAGTLTAFCPPSGRGVRVDTYGRPGLVVSP Mb3829c|M.bovis_AF2122/97 -------------------------------------------------- Rv3799c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_4982|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00731|M.leprae_Br4923 -------------------------------------------------- MSMEG_6577|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4676|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_0781|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0066|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_2343|M.thermoresistible__bu -------------------------------------------------- MMAR_1951|M.marinum_M LYDSLLAKVITHVHGSSFPAALRKARTVLSDFSIEGIATNAGLLREVLSD MAV_3657|M.avium_104 QYDSLLAKVIVAVHGSSWRAAMRKADTALSEFGVEGVATNIGFLRRLLAE Mb3829c|M.bovis_AF2122/97 -------------------------------------------------- Rv3799c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_4982|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00731|M.leprae_Br4923 -------------------------------------------------- MSMEG_6577|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4676|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_0781|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0066|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_2343|M.thermoresistible__bu -------------------------------------------------- MMAR_1951|M.marinum_M ERLVSGVVPTTFLDEILPALVEAAQSQQREVRVVALELYPGEQALRAQMA MAV_3657|M.avium_104 QRLETGWVNTDFVDDKLPELAAAALTHQPGPQPGAVELYPGEDALRAQLA Mb3829c|M.bovis_AF2122/97 -------------------------------------------------- Rv3799c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_4982|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00731|M.leprae_Br4923 -------------------------------------------------- MSMEG_6577|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4676|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_0781|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0066|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_2343|M.thermoresistible__bu -------------------------------------------------- MMAR_1951|M.marinum_M GTVVEVPPEGVDIGAGDQLVVLEAMKMQHVLAAPHRLHTVRILVTPGQVV MAV_3657|M.avium_104 GTVVEVAPEGADYPAGAQLVVLEAMKMQHVLAAPDALRTVRVLVTPGQVV Mb3829c|M.bovis_AF2122/97 -------------------------------------------------- Rv3799c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_4982|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00731|M.leprae_Br4923 -------------------------------------------------- MSMEG_6577|M.smegmatis_MC2_155 ------------------------MTDEDLRDDLAEVLRRRALTQDDARP MAB_4676|M.abscessus_ATCC_1997 ------------------------MADEQLREDHVELLARRALTEDAARP Mflv_0781|M.gilvum_PYR-GCK -----------------------MPEPEPVRDDLTELQRRRALTEDAARP Mvan_0066|M.vanbaalenii_PYR-1 -------------------------MPDPIRDDLAELWRRRALTEDAARP TH_2343|M.thermoresistible__bu -----------------------------MRPELAELLGRRRLTTDAARP MMAR_1951|M.marinum_M ATGDPLVVFCRTDAGEDVESSLAAVDLDRSRADLEEVRARHRLTLDEGRE MAV_3657|M.avium_104 GTGDPLLVFTRTTGGDDGESETAATDLDLTRADLDEVIERHARTLDEGRP Mb3829c|M.bovis_AF2122/97 ------MTVTEP-------------VLHTTAEKLAELRERLELAKEPGGE Rv3799c|M.tuberculosis_H37Rv ------MTVTEP-------------VLHTTAEKLAELRERLELAKEPGGE MUL_4982|M.ulcerans_Agy99 -------------------------MVHSTAEKLAELRERLELAKEPGGE MLBr_00731|M.leprae_Br4923 -----MTSVTDHSAHSMERAAEHTINIHTTAGKLAELHKRTEEALHPVGA . *: * : . MSMEG_6577|M.smegmatis_MC2_155 DAVERRRASGARTARQNIADLVDDGSFVEYGRFAIAAQRQRRSLDDLIAR MAB_4676|M.abscessus_ATCC_1997 DAVARRHAAGGRTARENISDLVDAGSFVEYGRFAIAAQRRRRELADLIAR Mflv_0781|M.gilvum_PYR-GCK DAVQRRHDAGGRTARENVADLVDPGSFVEYGRFAVAPQRMRRDVEDLIAR Mvan_0066|M.vanbaalenii_PYR-1 DAVERRHAAGGRTARENVADLVDTGSFVEYGRFAIAPQRMRRDVEDLITR TH_2343|M.thermoresistible__bu EAVQRRHGAGGRTARENIEDLVDPGSFVEYGRFVVAAQRQRRDLADLIAR MMAR_1951|M.marinum_M LAVGKRHKQGRRTARENIADLVDAGSFVEYGALAIAAQRSRRSEEDLIVS MAV_3657|M.avium_104 DAVAKRHRQGRRTARENIDDLVDPGSFVEYGALAIAAQRSRRSEEDLIAN Mb3829c|M.bovis_AF2122/97 KAAAKRDKKGIPSARARIYELVDPGSFMEIGALCRTPGD--------PNA Rv3799c|M.tuberculosis_H37Rv KAAAKRDKKGIPSARARIYELVDPGSFMEIGALCRTPGD--------PNA MUL_4982|M.ulcerans_Agy99 KAAAKRDKKGIPSARARVHALVDPGTFFETGALCKTPGD--------PGA MLBr_00731|M.leprae_Br4923 AAFEKVHAKGKFTARERIYALLDDDSFVELDALARHRSTN---FGLGENR * : * :** .: *:* .:*.* . : MSMEG_6577|M.smegmatis_MC2_155 TPADGLVAGTARVDG-------QPCAVLSYDYTVLAGTQGALGHLKKDRL MAB_4676|M.abscessus_ATCC_1997 TPADGLVAGTARVNGNLFGADRSACAVLSYDYTVLAGTQGALGHHKKDRL Mflv_0781|M.gilvum_PYR-GCK TPADGLIAGTARING-------DACAVLSYDYTVLAGTQGGLGHRKKDRL Mvan_0066|M.vanbaalenii_PYR-1 TPADGLVAGTARVDG-------HPCAVLSYDYTVLAGTQGALGHRKKDRL TH_2343|M.thermoresistible__bu TPADGLVAGTARING-------RPAAVLSYDYTVLAGTQGVFGHFKKDRL MMAR_1951|M.marinum_M TPADGLVAGLATIGADRFGNNAAEAVVVSYDYTVLAGTQGMRNHAKTDRV MAV_3657|M.avium_104 TPADGLVAGLATVGADRFGRAAAQAVVASYDYTVLAGTQGMRNHAKTDRV Mb3829c|M.bovis_AF2122/97 LYGDGVVTGHGLING-------RPVGVFSHDQTVFGGTVGEMFGRKVARL Rv3799c|M.tuberculosis_H37Rv LYGDGVVTGHGLING-------RPVGVFSHDQTVFGGTVGEMFGRKVARL MUL_4982|M.ulcerans_Agy99 LYGDGVVTGHAMIDG-------RPVGVFSHDQTVFQGSVGEMFGRKVARL MLBr_00731|M.leprae_Br4923 PVGDGVVTGYGTIDG-------RDVCIFSQDVTVFGGSLGEVYGEKIVKV .**:::* . :.. : * * **: *: * * :: MSMEG_6577|M.smegmatis_MC2_155 FDLIERMRLPTVFFAEGGGGRPGDTDIPTVSSLDVRAFKLWAALSGLVPR MAB_4676|M.abscessus_ATCC_1997 FDLIERMKLPTVFFAEGGGGRPGDTDYPVVSMLDVRAFKLWAALSGVVPR Mflv_0781|M.gilvum_PYR-GCK FELIERMALPTVFFAEGGGGRPVDTDYPVVSALDTRAFALWAKLSGQVPR Mvan_0066|M.vanbaalenii_PYR-1 FELIERMQLPTVFFAEGGGGRPGDTDYPVVSALDTRAFALWARLSGVVPR TH_2343|M.thermoresistible__bu FDLIERMRLPTVFFAEGGGGRPGDTDHPTVSSLQVRAFKLWAGLSGLVPR MMAR_1951|M.marinum_M FGLAARKRIPVVLFAEGGGGRPGDTDLGNISGLDVPTFRMLAGLSGRVPL MAV_3657|M.avium_104 FDLAARKRLPVVLFAEGGGGRPGDTDVGGAAGLDVPTFRMLAGLRGRVPL Mb3829c|M.bovis_AF2122/97 MEWCAMVGCPIVGINDSGGAR--IQDAVTSLAWYAELGRRHELLSGLVPQ Rv3799c|M.tuberculosis_H37Rv MEWCAMVGCPIVGINDSGGAR--IQDAVTSLAWYAELGRRHELLSGLVPQ MUL_4982|M.ulcerans_Agy99 MEWCSMVGCPIIGINDSAGAR--IQDTATSLAWYAELGRRHEILSGQVPQ MLBr_00731|M.leprae_Br4923 QELAIKTGRPLIGINDGAGAR--IQEGVVSLGLYSRIFRNNILASGVIPQ * : : :..*.* : * :* MSMEG_6577|M.smegmatis_MC2_155 IAVVRGRCFAGNAVIAGAADLIVATEDAS-IGMGGPAMIAGGGLGEVAPE MAB_4676|M.abscessus_ATCC_1997 ISVVNGRCFAGNAVIAGCSDLIVATKDTS-IGMGGPAMIAGGGLGEVHPD Mflv_0781|M.gilvum_PYR-GCK IAVVKGRCFAGNAVIAGASDLIVATRDAS-LGMGGPAMIAGGGLGAVAPD Mvan_0066|M.vanbaalenii_PYR-1 IAIVKGRCFAGNAVIAGASDLIVATRDAS-LGMGGPAMIAGGGLGDVPPD TH_2343|M.thermoresistible__bu IAVVKGRCFAGNAVIAGAADLIVATADTS-IGMGGPAMIAGGGLGDVHPD MMAR_1951|M.marinum_M VSIVSGRCFAGNAALAGVCDVIIATPDAN-IGMGGPAMIEGGGLGVYPPE MAV_3657|M.avium_104 VSVVSGRCFAGNAALAGVCDVIIATPDAN-IGMGGPAMIEGGGLGVYPPE Mb3829c|M.bovis_AF2122/97 ISIILGKCAGGAVYSPIQTDLVVAVRDQGYMFVTGPDVIKDVTGEDVSLD Rv3799c|M.tuberculosis_H37Rv ISIILGKCAGGAVYSPIQTDLVVAVRDQGYMFVTGPDVIKDVTGEDVSLD MUL_4982|M.ulcerans_Agy99 ISIILGKCAGGAVYSPIQTDLVVAVRDQGYMFVTGPDVIKDVTGEDVSLD MLBr_00731|M.leprae_Br4923 ISLIMGAAAGGHVYSPALTDFVVMVDQTSQMFITGPDVIKTVTGEDVTME :::: * . .* . . *.:: . : . : : ** :* : MSMEG_6577|M.smegmatis_MC2_155 DVGPIS-VQAPNGVVDIVVADEPEAVAVTKTLLGYFGG------------ MAB_4676|M.abscessus_ATCC_1997 EVGPIA-VQSTNGVVDVVVDDEEQAVTVAKRLISYFQG------------ Mflv_0781|M.gilvum_PYR-GCK DVGPMS-VQEPNGNVDVVVDDEAAAVAVAKRLIGYFQG------------ Mvan_0066|M.vanbaalenii_PYR-1 EVGPMT-TQEPNGNVDVVVDDEAEAVAVTKTLLGYFQG------------ TH_2343|M.thermoresistible__bu EVGPIS-VQEPNGVVDLVVADETEAVAAARRLLGYFQG------------ MMAR_1951|M.marinum_M AIGPID-VQRRNGVVSLVARDEAHAVSLAKRYLGYFQG------------ MAV_3657|M.avium_104 AIGPIA-VQRRNGVVGLVARDEAHAVSLAKQYLSYFQG------------ Mb3829c|M.bovis_AF2122/97 ELGGAD-HQASYGNIHQVVESEAAAYQYVRDFLSFLPSNCFDKPP----- Rv3799c|M.tuberculosis_H37Rv ELGGAD-HQASYGNIHQVVESEAAAYQYVRDFLSFLPSNCFDKPP----- MUL_4982|M.ulcerans_Agy99 ELGGAD-SQARYGNIHQVVEDEAAAFQYVRDFLSFLPSDCFGDPP----- MLBr_00731|M.leprae_Br4923 ELGGAHTHMAKSGTAHYVASGEQDAFDWVRDVLSYLPSNNFTDAPRYSKP :* * *. .* * .: :.:: . MSMEG_6577|M.smegmatis_MC2_155 ----PVDAGPERDQTPLRTMVPERARRAYPVGPVIETLADEGSVTYLREK MAB_4676|M.abscessus_ATCC_1997 ----AVAPGDGADQTALRTMIPERARRAYPIRPIIETLADTGSVTFLREK Mflv_0781|M.gilvum_PYR-GCK ----CVSQWSAPDQTPLRTAVPERARRAYDVAPVIETLADEDSVTFLRPR Mvan_0066|M.vanbaalenii_PYR-1 ----PADSWSAPDQTVLRTAVPDRARRAYDVAPVIETIADEDSVTFLRPR TH_2343|M.thermoresistible__bu ----STAPGEVADQTVLRTMVPERARRAYDVTPVIETLADADSVTVLRPR MMAR_1951|M.marinum_M ----KVEGWQAPDPRLARQVVPENRLRAYDVHRAIESIVDVGSVLELRAD MAV_3657|M.avium_104 ----RLDRWQAPDPRVARHVVPQNRLRAYDVHRAIEAIVDVGSVLELRPD Mb3829c|M.bovis_AF2122/97 VVNPGLEPEITGHDLELDSIVPDSDNMAYDMHEVLLRIFDDGDFLDVAAQ Rv3799c|M.tuberculosis_H37Rv VVNPGLEPEITGHDLELDSIVPDSDNMAYDMHEVLLRIFDDGDFLDVAAQ MUL_4982|M.ulcerans_Agy99 VVNPGLEPEITPSDLELDSIVPDSDNTAYDMHEILLRIFDDGDFLDVAAQ MLBr_00731|M.leprae_Br4923 VPHGSIEDNLTAKDLELDTLIPDSPNQPYDMHEVVTRLLDEEEFLEVQAG :*: .* : : : * .. : MSMEG_6577|M.smegmatis_MC2_155 FAPEMVTAFARMAGRPVGILANNTMVMAGAITATASDKAARFLQLCDAFG MAB_4676|M.abscessus_ATCC_1997 FAPEMATALARIEGRPIGVLANNSMVMAGAITAAASDKAARFLQLCDAFG Mflv_0781|M.gilvum_PYR-GCK FAREMVTALARIEGRPVGVIANDTRFTAGAITAAASDKAARFLQLCDAFG Mvan_0066|M.vanbaalenii_PYR-1 FAREMVTALARVEGRPVGVIANDTRFTAGAITAAASDKAARFLQLCDAFG TH_2343|M.thermoresistible__bu FAREMVTALARIDGRPVGVLANDTRYMAGAITAAASDKAARFLQLCDVFG MMAR_1951|M.marinum_M YGVGIVTALVRIEGFAYGLIANSSHHLGGAIDAEASDKVTDFLMLCESFR MAV_3657|M.avium_104 YGVGIVTALVRVEGVPCGLIANSTHHLGGAIDAEAADKAGDFLALCESFG Mb3829c|M.bovis_AF2122/97 AGQAIITGYARVDGRTVGVVANQPMHMSGAIDNEASDKAARFIRFSDAFD Rv3799c|M.tuberculosis_H37Rv AGQAIITGYARVDGRTVGVVANQPMHMSGAIDNEASDKAARFIRFSDAFD MUL_4982|M.ulcerans_Agy99 ASQAIITGYARVDGRPVGVVANQPMHMSGAIDNEASDKAARFVRFCDAFK MLBr_00731|M.leprae_Br4923 YATNIVVGLGRIDDRPVGIVANQPIQFAGCLDINASEKAARFVRVCDCFN . : .. *: . . *::**.. .*.: *::*. *: ..: * MSMEG_6577|M.smegmatis_MC2_155 IPVVSLVDCPGYMVGPAAEAEALVRRGSRLLVAGAALTVPLIAVILRRGY MAB_4676|M.abscessus_ATCC_1997 LPVLSLVDCPGYMVGPAAEAEALVRRASRMLVAGAALRVPLVSVILRRGY Mflv_0781|M.gilvum_PYR-GCK LPVVSLIDCPGYMVGPAAEAESLVRRASRMLVAGAALRVPLIAVILRRGY Mvan_0066|M.vanbaalenii_PYR-1 FPVVSLIDCPGYMVGPAAEAESLVRRASRMLVAGAALCVPMVAVILRRGY TH_2343|M.thermoresistible__bu LPVISLIDCPGYMVGPAAEAEALVRRGSRLLVAGAALRVPLIAVVLRRGY MMAR_1951|M.marinum_M LPVISLCDTPGFMVGPDAETQASVRRFGRMFLAGARLTVPLGMIILRKGY MAV_3657|M.avium_104 LPVISLCDTPGFMVGPDAETQAAVRRFGRMFVLGARLTVPLGMIILRKGY Mb3829c|M.bovis_AF2122/97 IPLVFVVDTPGFLPGVEQEKNGIIKRGGRFLYAVVEADVPKVTITIRKSY Rv3799c|M.tuberculosis_H37Rv IPLVFVVDTPGFLPGVEQEKNGIIKRGGRFLYAVVEADVPKVTITIRKSY MUL_4982|M.ulcerans_Agy99 IPLVFVVDTPGFLPGAEQEKNGIIKRGGRFLYAVVEADVPKVTITIRKSY MLBr_00731|M.leprae_Br4923 IPIVMLVDVPGFLPGTEQEYDGIIRRGAKLLFAYGEATVPKITVITRKAY :*:: : * **:: * * :. ::* .::: ** : *:.* MSMEG_6577|M.smegmatis_MC2_155 GLGAQAMCGGSLHEPLLTVAWPGAHLGPMGLEGAVRLGMRKELEAIENEG MAB_4676|M.abscessus_ATCC_1997 GLGAQAMTGGSLHEPLLTVAWPNAHLGPMGLEGAVRLGLRKELEAIADES Mflv_0781|M.gilvum_PYR-GCK GLGAQAMAGGSLHEPLLTVAWPGAHLGPMGLEGAVRLGMRKELEAIADEA Mvan_0066|M.vanbaalenii_PYR-1 GLGAQAMAGGSLHEPVLTVAWPGAHLGPMGLEGAVRLGMRKELDAIEDEQ TH_2343|M.thermoresistible__bu GLGAQAMAGGGLHEPVLTVAWPGAHLGPMGLEGAVRLGMRKELEAIADEA MMAR_1951|M.marinum_M GLGAMAMAGGSFHAPEFTIAWPTGEIGGMGLEGAVRLGFSKELAAAADDI MAV_3657|M.avium_104 GLGAMAMAGGSFRAPQFTVAWPTGEIGGMGLEGAVRLGYRKELAAVTDPA Mb3829c|M.bovis_AF2122/97 G-GAYAVMGSKQLTADLNFAWPTARIAVIGADGAAQLLMKRFPDPNAP-- Rv3799c|M.tuberculosis_H37Rv G-GAYAVMGSKQLTADLNFAWPTARIAVIGADGAAQLLMKRFPDPNAP-- MUL_4982|M.ulcerans_Agy99 G-GAYAVMGSKQLTADFNFAWPTARIAVIGADGAAQLLMKRFPDPTTP-- MLBr_00731|M.leprae_Br4923 G-GAYCVMGSKNMGCDVNLAWPTAQIAVMGASGAVGFVYRKELAQAAKNG * ** .: *. ...*** ..:. :* .**. : : MSMEG_6577|M.smegmatis_MC2_155 AREEAVRAATKAAEEH--AKALNSASMFEIDDVIDPAETRSVIISTLVAA MAB_4676|M.abscessus_ATCC_1997 AREEAVRQATAAAQEN--AKAINAAQIFEIDDVIDPAETRSLVASTFAAA Mflv_0781|M.gilvum_PYR-GCK EREARVVAATAAAQEY--AKALNAAMLFEIDDVIDPAETRAVIAATLVAA Mvan_0066|M.vanbaalenii_PYR-1 EREERVRLATAAAQEN--AKALNAAMLFEIDDVIDPAETRAVIAATFAAA TH_2343|M.thermoresistible__bu EREERVRQATAAAQRH--AAALNAAMHFEIDDVVDPAETRGLIAATLAAA MMAR_1951|M.marinum_M ERQELFDRLVQAAYQH--GKALRSATTFELDDVIDPAESRAWITRLPGR- MAV_3657|M.avium_104 ERQNLFDRLVAAAYQH--GKALRAATTFELDDVIDPAASRAWITRLSEG- Mb3829c|M.bovis_AF2122/97 -EAQAIRKSFVENYNLNMAIPWIAAERGFIDAVIDPHETRLLLRKSMHLL Rv3799c|M.tuberculosis_H37Rv -EAQAIRKSFVENYNLNMAIPWIAAERGFIDAVIDPHETRLLLRKSMHLL MUL_4982|M.ulcerans_Agy99 -EAQKIKRDFIEGYNLNMAIPWIAAERGYIDAVVDPHQTRLLLRKSMHLL MLBr_00731|M.leprae_Br4923 ANVDELRLQLQQEYEDTLVNPYIAAERGYVDAVIPPSHTRGYIATALHLL . . . . :* :* *: * :* : MSMEG_6577|M.smegmatis_MC2_155 AHHEHANRPR------FVDTW MAB_4676|M.abscessus_ATCC_1997 MREPLPLRRS------VVDTW Mflv_0781|M.gilvum_PYR-GCK DSGTKKPAPDRS---RFIDTW Mvan_0066|M.vanbaalenii_PYR-1 DTDTRKPAPGGSRFGRFVDTW TH_2343|M.thermoresistible__bu TAAPRDRPPR-----RFVDTW MMAR_1951|M.marinum_M --------------------- MAV_3657|M.avium_104 --------------------- Mb3829c|M.bovis_AF2122/97 RDKQLWWRVGRKHGLIPV--- Rv3799c|M.tuberculosis_H37Rv RDKQLWWRVGRKHGLIPV--- MUL_4982|M.ulcerans_Agy99 RDKQLWWRVGRKHGLIPV--- MLBr_00731|M.leprae_Br4923 ERKIAHLPP-KKHGNIPL---